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gsk-3

gsk-3

GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.

Found 112 products of "gsk-3"

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  • GSK-3 inhibitor 3
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    GSK-3 inhibitor 3

    CAS:
    <p>GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively</p>
    Formula:C23H15FN6O
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:410.4

    Ref: TM-T77342

  • Kinase Inhibitor Library
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    Kinase Inhibitor Library

    <p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>
    Color and Shape:Odour Solid

    Ref: TM-L1600

  • 2B-(SP)
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    2B-(SP)

    CAS:
    <p>Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3)</p>
    Formula:C71H123N26O29P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1835.87

    Ref: TM-TP2211

  • MeBIO
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    MeBIO

    CAS:
    <p>MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.</p>
    Formula:C17H12BrN3O2
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:370.2

    Ref: TM-T21966

  • CymitQuimica logo
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    GSK-3β inhibitor 21

    <p>GSK-3β Inhibitor21 (compound 44) is an ATP-competitive inhibitor of GSK-3β with an IC50 value of 6.06 µM, characterized by its ability to inhibit tau phosphorylation and prevent amyloid protein aggregation. This compound is utilized in the research of Alzheimer's disease.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200736

  • FRATide
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    FRATide

    CAS:
    <p>FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.</p>
    Formula:C55H102N2O2
    Color and Shape:Solid
    Molecular weight:823.433

    Ref: TM-T35550

  • Phospho-Glycogen Synthase Peptide-2(substrate)
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    Phospho-Glycogen Synthase Peptide-2(substrate)

    CAS:
    <p>Phospho-Glycogen Synthase Peptide-2 is a GSK-3 substrate, useful for serine kinase affinity purification.</p>
    Formula:C123H191N40O48P
    Color and Shape:Solid
    Molecular weight:3029.087

    Ref: TM-T40945

  • CHIR-98023
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    CHIR-98023

    CAS:
    <p>CHIR-98023 is a bio-active chemical.</p>
    Formula:C20H16Cl2N8O2
    Color and Shape:Solid
    Molecular weight:471.30

    Ref: TM-T30884

  • GSK3a-IN-38
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    GSK3a-IN-38

    CAS:
    <p>GSK3a-IN-38 is a novel small molecule compound that has inhibitory effects on GSK-3a.</p>
    Formula:C18H20N4O
    Purity:99.75%
    Color and Shape:Soild
    Molecular weight:308.38

    Ref: TM-T77671

  • CymitQuimica logo
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    GSK3β/mTOR modulator 1

    <p>GSK3β/mTOR modulator 1 (derivative 2) is an agent that modulates the GSK3β/mTOR signaling pathway. It is applicable in research related to acute lung injury (ALI) and inflammation.</p>
    Formula:C19H28O5
    Color and Shape:Solid
    Molecular weight:336.19367

    Ref: TM-T207314

  • Ceftriaxone Sodium
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    Ceftriaxone Sodium

    CAS:
    <p>Ceftriaxone Sodium is a sporotaxin antibiotic that inhibits GSK3β and Aurora B. It is used in the study of sepsis and infective endocarditis.</p>
    Formula:C18H17N8NaO7S3
    Color and Shape:Solid
    Molecular weight:576.562

    Ref: TM-T66175

  • BIO-acetoxime
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    BIO-acetoxime

    CAS:
    <p>BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, &gt;240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.</p>
    Formula:C18H12BrN3O3
    Purity:97.15%
    Color and Shape:Solid
    Molecular weight:398.21

    Ref: TM-T6787

  • Bikinin
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    Bikinin

    CAS:
    <p>Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.</p>
    Formula:C9H9BrN2O3
    Purity:99.86% - >99.99%
    Color and Shape:Solid
    Molecular weight:273.08

    Ref: TM-T1965

  • SB 415286
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    SB 415286

    CAS:
    <p>SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.</p>
    Formula:C16H10ClN3O5
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:359.72

    Ref: TM-T6659

  • VP3.15 dihydrobromide
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    VP3.15 dihydrobromide

    CAS:
    <p>VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.</p>
    Formula:C20H24Br2N4OS
    Purity:99.67% - ≥95%
    Color and Shape:Solid
    Molecular weight:528.3

    Ref: TM-T5956

  • Indirubin-3′-oxime
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    Indirubin-3′-oxime

    CAS:
    <p>Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.</p>
    Formula:C16H11N3O2
    Purity:98.34%
    Color and Shape:Solid
    Molecular weight:277.28

    Ref: TM-T9138

  • TDZD-8
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    TDZD-8

    CAS:
    <p>TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.</p>
    Formula:C10H10N2O2S
    Purity:97.13% - 99.61%
    Color and Shape:White Solid
    Molecular weight:222.26

    Ref: TM-T6187

  • AZD1080
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    AZD1080

    CAS:
    <p>AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.</p>
    Formula:C19H18N4O2
    Purity:97.72% - 99.75%
    Color and Shape:Solid
    Molecular weight:334.37

    Ref: TM-T1741

  • GSK-3β inhibitor 10
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    GSK-3β inhibitor 10

    CAS:
    <p>GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.</p>
    Formula:C12H12N2O3S
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:264.3

    Ref: TM-T9725

  • CP21R7
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    CP21R7

    CAS:
    <p>CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.</p>
    Formula:C19H15N3O2
    Purity:96.14% - 99.16%
    Color and Shape:Solid
    Molecular weight:317.34

    Ref: TM-T3684