gsk-3
GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.
Found 107 products for "gsk-3".
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GSK-3β inhibitor 14
CAS:GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) is a weak GSK-3β inhibitor, IC50﹥ 100μM.Formula:C17H17NOSPurity:99.97%Color and Shape:SolidMolecular weight:283.39GSK3β Inhibitor XI
CAS:GSK3β Inhibitor XI has GSK3β inhibitory effect.Formula:C18H15N5O3Color and Shape:SolidMolecular weight:349.35Phospho-Glycogen Synthase Peptide-2(substrate)
CAS:Phospho-Glycogen Synthase Peptide-2 is a GSK-3 substrate, useful for serine kinase affinity purification.Formula:C123H191N40O48PColor and Shape:SolidMolecular weight:3029.087MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Formula:C17H12BrN3O2Purity:99.64%Color and Shape:SolidMolecular weight:370.2Ref: TM-T21966
1mg37.00€5mg71.00€1mL*10mM (DMSO)81.00€10mg111.00€25mg208.00€50mg335.00€100mg492.00€500mg1,071.00€Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Color and Shape:Odour SolidRef: TM-L1600
1mgTo inquire10μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquireyGsy2p-IN-H23
CAS:yGsy2p-IN-H23 targets yeast GSY2 with IC50 of 875μM for hGYS1, for GSD research.Formula:C23H27N3O2Color and Shape:SolidMolecular weight:377.488VP3.15 dihydrobromide
CAS:VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.Formula:C20H24Br2N4OSPurity:99.67% - ≥95%Color and Shape:SolidMolecular weight:528.3IM-12
CAS:IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.Formula:C22H20FN3O2Purity:99.42% - >99.99%Color and Shape:Orange SolidMolecular weight:377.41Ref: TM-T2261
500mgTo inquire2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg82.00€25mg146.00€50mg222.00€100mg334.00€Indirubin-3′-oxime
CAS:Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.Formula:C16H11N3O2Purity:98.34%Color and Shape:SolidMolecular weight:277.28Ref: TM-T9138
1mg44.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg120.00€25mg236.00€50mg356.00€100mg532.00€200mg772.00€Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formula:C16H11N3O2Purity:99.55%Color and Shape:Red SolidMolecular weight:277.28GSK-3β inhibitor 10
CAS:GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.Formula:C12H12N2O3SPurity:98.06%Color and Shape:SolidMolecular weight:264.3CP21R7
CAS:CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formula:C19H15N3O2Purity:96.14% - 99.16%Color and Shape:SolidMolecular weight:317.34Ref: TM-T3684
1mg38.00€2mg50.00€1mL*10mM (DMSO)77.00€5mg84.00€10mg120.00€25mg236.00€50mg356.00€100mg537.00€CHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formula:C22H18Cl2N8Purity:97.94% - ≥95%Color and Shape:White SolidMolecular weight:465.34Ref: TM-T2310
2mg40.00€5mg60.00€1mL*10mM (DMSO)62.00€10mg92.00€25mg152.00€50mg240.00€100mg384.00€200mg572.00€500mg888.00€Tideglusib
CAS:Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities.Formula:C19H14N2O2SPurity:98.40% - 99.35%Color and Shape:SolidMolecular weight:334.39Ref: TM-T3067
1mL*10mM (DMSO)33.00€10mg44.00€25mg73.00€50mg107.00€100mg177.00€200mg268.00€500mg465.00€RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:95.67% - 99.91%Color and Shape:SolidMolecular weight:545.63SB 216763
CAS:SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formula:C19H12Cl2N2O2Purity:98.89% - 99.13%Color and Shape:SolidMolecular weight:371.22Ref: TM-T3077
2mg37.00€5mg50.00€1mL*10mM (DMSO)50.00€10mg74.00€25mg124.00€50mg187.00€100mg315.00€500mg762.00€BIO-acetoxime
CAS:BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.Formula:C18H12BrN3O3Purity:97.15%Color and Shape:SolidMolecular weight:398.21Ref: TM-T6787
1mg34.00€2mg46.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg99.00€25mg177.00€50mg281.00€100mg439.00€AZD2858
CAS:AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.Formula:C21H23N7O3SPurity:99.25% - 99.36%Color and Shape:SolidMolecular weight:453.52Bikinin
CAS:Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.Formula:C9H9BrN2O3Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:273.083Ref: TM-T1965
1mL*10mM (DMSO)33.00€10mg44.00€25mg73.00€50mg113.00€100mg177.00€200mg264.00€500mg447.00€LY2090314
CAS:LY2090314, a potent GSK-3α/β blocker (IC50: 1.5/0.9 nM), could boost platinum chemo. Tested in leukemia and advanced cancers.Formula:C28H25FN6O3Purity:99.21% - 99.91%Color and Shape:SolidMolecular weight:512.53Ref: TM-T1755
1mg34.00€2mg50.00€5mg90.00€1mL*10mM (DMSO)92.00€10mg131.00€25mg225.00€50mg369.00€100mg545.00€200mg777.00€
