gsk-3
GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.
Found 109 products of "gsk-3"
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Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formula:C25H24N4O2Purity:97.51% - 98.75%Color and Shape:Orange SolidMolecular weight:412.48SB 216763
CAS:SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formula:C19H12Cl2N2O2Purity:98.9% - 99.13%Color and Shape:SolidMolecular weight:371.22Ref: TM-T3077
2mg39.00€5mg52.00€10mg79.00€25mg131.00€50mg197.00€100mg334.00€500mg803.00€1mL*10mM (DMSO)52.00€CP21R7
CAS:CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formula:C19H15N3O2Purity:96.14% - 99.16%Color and Shape:SolidMolecular weight:317.34Ref: TM-T3684
1mg38.00€2mg50.00€5mg84.00€10mg120.00€25mg236.00€50mg356.00€100mg537.00€1mL*10mM (DMSO)77.00€GSK 3 Inhibitor IX
CAS:GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.Formula:C16H10BrN3O2Purity:98% - 99.72%Color and Shape:SolidMolecular weight:356.17Ref: TM-T1917
1mg42.00€2mg52.00€5mg78.00€10mg96.00€25mg216.00€50mg389.00€100mg577.00€500mg1,234.00€1mL*10mM (DMSO)86.00€Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formula:C16H11N3O2Purity:99.55%Color and Shape:Dark Red SolidMolecular weight:277.28PF-04802367
CAS:PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.Formula:C16H16ClN5O3Purity:98.76%Color and Shape:SolidMolecular weight:361.78Ref: TM-T9611
1mg49.00€5mg100.00€10mg152.00€25mg264.00€50mg399.00€100mg532.00€200mg705.00€1mL*10mM (DMSO)111.00€KY19382
CAS:KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may help in metabolic disease research.Formula:C17H11Cl2N3O2Purity:98.06%Color and Shape:SolidMolecular weight:360.19Ref: TM-T9025
1mg94.00€5mg187.00€10mg333.00€25mg560.00€50mg797.00€100mg1,071.00€500mg2,187.00€1mL*10mM (DMSO)230.00€IM-12
CAS:IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.
Formula:C22H20FN3O2Purity:99.42% - >99.99%Color and Shape:SolidMolecular weight:377.41Tideglusib
CAS:Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities.Formula:C19H14N2O2SPurity:98.40% - 99.35%Color and Shape:SolidMolecular weight:334.39Ref: TM-T3067
10mg47.00€25mg77.00€50mg113.00€100mg187.00€200mg283.00€500mg490.00€1mL*10mM (DMSO)50.00€LY2090314
CAS:LY2090314, a potent GSK-3α/β blocker (IC50: 1.5/0.9 nM), could boost platinum chemo. Tested in leukemia and advanced cancers.Formula:C28H25FN6O3Purity:99.21% - 99.91%Color and Shape:SolidMolecular weight:512.53Ref: TM-T1755
1mg37.00€2mg52.00€5mg95.00€10mg138.00€25mg238.00€50mg389.00€100mg575.00€200mg820.00€1mL*10mM (DMSO)97.00€GS87
CAS:GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.Formula:C16H11N5O2SPurity:98.86%Color and Shape:SolidMolecular weight:337.36Ref: TM-T8605
1mg84.00€5mg166.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€1mL*10mM (DMSO)170.00€AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Formula:C19H18N4O2Purity:97.72% - 99.75%Color and Shape:SolidMolecular weight:334.37Ref: TM-T1741
1mg43.00€2mg56.00€5mg85.00€10mg124.00€25mg219.00€50mg350.00€100mg429.00€1mL*10mM (DMSO)63.00€BIO-acetoxime
CAS:BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.
Formula:C18H12BrN3O3Purity:97.15%Color and Shape:SolidMolecular weight:398.21Bikinin
CAS:Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.
Formula:C9H9BrN2O3Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:273.08SB 415286
CAS:SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.Formula:C16H10ClN3O5Purity:99.55%Color and Shape:SolidMolecular weight:359.72GSK-3β inhibitor 10
CAS:GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.Formula:C12H12N2O3SPurity:98.06%Color and Shape:SolidMolecular weight:264.3RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:98% - 99.91%Color and Shape:SolidMolecular weight:545.63GNF4877
CAS:GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.Formula:C25H27FN6O4Purity:98.68% - 99.40%Color and Shape:SolidMolecular weight:494.52(E/Z)-GSK-3β inhibitor 1
CAS:(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.Formula:C14H10N2OPurity:98.60%Color and Shape:SolidMolecular weight:222.24Ref: TM-T9178
2mg35.00€5mg56.00€10mg94.00€25mg154.00€50mg222.00€100mg318.00€200mg432.00€1mL*10mM (DMSO)63.00€7BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17
