gsk-3
GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.
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GSK-3β inhibitor 11
CAS:536731-65-4
GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with …
Formula:
C20H15N3O4S
Purity:
97.33%
Color and Shape:
Liquid
Molecular weight:
393.42
Ref: TM-T61809
| 5mg | 74.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 549.00 € | ||
| 500mg | 1,171.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
3F8
CAS:159109-11-2
3F8 is a selective GSK-3β inhibitor that can be used as a new tool and …
Formula:
C15H14N2O4
Purity:
98.05% - 98.49%
Color and Shape:
Solid
Molecular weight:
286.28
Ref: TM-T22180
| 1mg | 111.00 € | ||
| 5mg | 266.00 € | ||
| 10mg | 427.00 € | ||
| 25mg | 689.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,268.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Aloisine B
CAS:496864-14-3
Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 …
Formula:
C15H14ClN3
Purity:
95.15%
Color and Shape:
Liquid
Molecular weight:
271.74
Ref: TM-T69188
| 1mg | 326.00 € | ||
| 5mg | 772.00 € | ||
| 10mg | 1,050.00 € | ||
| 25mg | 1,477.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,322.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
CHIR-99021 HCl
CAS:1797989-42-4
CHIR-99021 HCl is a selective GSK-3α/β inhibitor (IC50: 10/6.7 nM), 500x selective over other kinases, …
Formula:
C22H19Cl3N8
Purity:
98.07% - 98.44%
Color and Shape:
Solid
Molecular weight:
501.8
Ref: TM-T2310L
| 1mg | 36.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 241.00 € | ||
| 100mg | 466.00 € | ||
| 200mg | 676.00 € | ||
| 500mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
BIP-135
CAS:941575-71-9
BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor.
Formula:
C21H13BrN2O3
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
421.24
Ref: TM-T14613
| 1mg | 34.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 318.00 € | ||
| 100mg | 455.00 € | ||
| 200mg | 628.00 € | ||
| 1mL*10mM (DMSO) | 83.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
EHT 1610
CAS:1425945-60-3
EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 …
Formula:
C18H14FN5O2S
Purity:
98.27%
Color and Shape:
Solid
Molecular weight:
383.4
Ref: TM-T15204
| 1mg | 96.00 € | ||
| 5mg | 211.00 € | ||
| 10mg | 315.00 € | ||
| 25mg | 509.00 € | ||
| 50mg | 692.00 € | ||
| 100mg | 936.00 € | ||
| 200mg | 1,257.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
CCG 203769
CAS:410074-60-1
CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 …
Formula:
C8H14N2O2S
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
202.27
Ref: TM-T10705
| 1mg | 87.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 457.00 € | ||
| 50mg | 642.00 € | ||
| 100mg | 921.00 € | ||
| 500mg | 1,836.00 € | ||
| 1mL*10mM (DMSO) | 205.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
MBM-55
CAS:2083622-09-5
MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of …
Formula:
C28H27FN6O2
Purity:
99.98%
Color and Shape:
Solid
Molecular weight:
498.55
Ref: TM-T11960
| 1mg | 175.00 € | ||
| 5mg | 291.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 647.00 € | ||
| 50mg | 848.00 € | ||
| 100mg | 1,149.00 € | ||
| 500mg | 2,311.00 € | ||
| 1mL*10mM (DMSO) | 324.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
K 00546
CAS:443798-47-8
K00546 inhibits CDK1/cyclin B (IC50: 0.6 nM), CDK2/cyclin A (IC50: 0.5 nM), CLK1 (IC50: 8.9 …
Formula:
C15H13F2N7O2S2
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
425.44
Ref: TM-T21950
| 1mg | 95.00 € | ||
| 5mg | 242.00 € | ||
| 25mg | 839.00 € | ||
| 50mg | 1,076.00 € | ||
| 100mg | 1,660.00 € | ||
| 1mL*10mM (DMSO) | 292.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
PIMPC
CAS:2250244-44-9
PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of …
Formula:
C21H19N5O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
357.41
Ref: TM-T79693
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
ARN25068
CAS:2649882-80-2
ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.
Formula:
C19H18N6S
Purity:
99.71%
Color and Shape:
Liquid
Molecular weight:
362.45
Ref: TM-T61360
| 1mg | 111.00 € | ||
| 5mg | 266.00 € | ||
| 10mg | 430.00 € | ||
| 25mg | 867.00 € | ||
| 50mg | 1,161.00 € | ||
| 100mg | 1,561.00 € | ||
| 500mg | 3,139.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Laduviglusib trihydrochloride
CAS:1782235-14-6
Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.
Formula:
C22H20Cl5N8
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
573.71
Ref: TM-T22657
| 1mg | 42.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 263.00 € | ||
| 50mg | 498.00 € | ||
| 100mg | 667.00 € | ||
| 500mg | 1,392.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
GSK-3β inhibitor 12
CAS:784170-07-6
GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM …
Formula:
C14H13N3OS
Purity:
98.42%
Color and Shape:
Liquid
Molecular weight:
271.34
Ref: TM-T60472
| 1mg | 72.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 593.00 € | ||
| 100mg | 816.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Dehydroglyasperin D
CAS:517885-72-2
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation …
Formula:
C22H24O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
368.42
Ref: TM-TMA0291
| 25mg | 1,549.00 € | ||
| 50mg | 2,031.00 € | ||
| 100mg | 2,609.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
GSK-3β inhibitor 2
CAS:1702428-31-6
GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50
Formula:
C14H14N4O3S
Purity:
95.69%
Color and Shape:
Solid
Molecular weight:
318.35
Ref: TM-T11471
| 5mg | 54.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 103.00 € | ||
| 50mg | 183.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
MBM-55S
CAS:2083624-07-9
MBM-55S, a Nek2 inhibitor with 1 nM IC50, induces cell cycle arrest and apoptosis, suppressing …
Formula:
C36H39FN6O10
Purity:
98.38% - 98.73%
Color and Shape:
Solid
Molecular weight:
734.73
Ref: TM-T11961
| 1mg | 183.00 € | ||
| 2mg | 273.00 € | ||
| 5mg | 422.00 € | ||
| 10mg | 618.00 € | ||
| 25mg | 926.00 € | ||
| 50mg | 1,304.00 € | ||
| 100mg | 1,763.00 € | ||
| 500mg | 3,508.00 € | ||
| 1mL*10mM (DMSO) | 622.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
(Rac)-BRD0705
CAS:1597440-03-3
(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is an effective and selective inhibitor …
Formula:
C20H23N3O
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
321.42
Ref: TM-T12664
| 1mg | 95.00 € | ||
| 5mg | 208.00 € | ||
| 10mg | 311.00 € | ||
| 25mg | 501.00 € | ||
| 50mg | 682.00 € | ||
| 100mg | 923.00 € | ||
| 1mL*10mM (DMSO) | 154.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
5-Iodo-indirubin-3'-monoxime
CAS:331467-03-9
5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding …
Formula:
C16H10IN3O2
Color and Shape:
Solid
Molecular weight:
403.17
Ref: TM-T10172
| 5mg | 278.00 € | ||
| 25mg | 916.00 € | ||
| 50mg | 1,273.00 € | ||
| 100mg | 1,741.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
BRD5648
CAS:2056261-42-6
BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.
Formula:
C20H23N3O
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
321.42
Ref: TM-T10608
| 1mg | 68.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 200.00 € | ||
| 25mg | 334.00 € | ||
| 50mg | 463.00 € | ||
| 100mg | 645.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
GSK-3β inhibitor 8
CAS:1139875-74-3
GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an …
Formula:
C20H20ClN5OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
413.92
Ref: TM-T35556
| 1mg | 108.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
