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gsk-3

gsk-3

GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.

Found 112 products of "gsk-3"

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  • 4-Chloro-2'-bromoacetophenone
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    4-Chloro-2'-bromoacetophenone

    CAS:
    <p>4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).</p>
    Formula:C8H6BrClO
    Purity:98.34% - 99.41%
    Color and Shape:White To Beige Solid
    Molecular weight:233.49

    Ref: TM-T8908

  • KenPaullone
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    KenPaullone

    CAS:
    <p>KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation.</p>
    Formula:C16H11BrN2O
    Purity:97.14% - 98.99%
    Color and Shape:Tan Solid
    Molecular weight:327.18

    Ref: TM-T2247

  • VP3.15 dihydrobromide
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    VP3.15 dihydrobromide

    CAS:
    <p>VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.</p>
    Formula:C20H24Br2N4OS
    Purity:99.67% - ≥95%
    Color and Shape:Solid
    Molecular weight:528.3

    Ref: TM-T5956

  • CHIR-98014
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    CHIR-98014

    CAS:
    <p>CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.</p>
    Formula:C20H17Cl2N9O2
    Purity:97.25% - 99.59%
    Color and Shape:Solid
    Molecular weight:486.31

    Ref: TM-T2608

  • ALSTERPAULLONE
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    ALSTERPAULLONE

    CAS:
    <p>Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec</p>
    Formula:C16H11N3O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:293.28

    Ref: TM-T7426

  • AR-A014418
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    AR-A014418

    CAS:
    <p>AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.</p>
    Formula:C12H12N4O4S
    Purity:>99.99% - ≥95%
    Color and Shape:Solid
    Molecular weight:308.31

    Ref: TM-T1881

  • CHIR 98024
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    CHIR 98024

    CAS:
    <p>CHIR 98024: strong GSK-3α/β blocker, IC50 0.65/0.58 nM, selective over Cdc2/ERK2.</p>
    Formula:C20H17Cl2N9O2
    Purity:96.74%
    Color and Shape:Solid
    Molecular weight:486.31

    Ref: TM-T3074

  • 1-Azakenpaullone
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    1-Azakenpaullone

    CAS:
    <p>1-Azakenpaullone (azakenpaullone) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, &gt;100-fold selectivity over CDK1/cyclin B and CDK5/p25.</p>
    Formula:C15H10BrN3O
    Purity:99.73%
    Color and Shape:Tan Solid
    Molecular weight:328.16

    Ref: TM-T6358

  • BRD0209
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    BRD0209

    CAS:
    <p>BRD0209 is a highly selective and potent GSK3 inhibitor.</p>
    Formula:C22H25N3O
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:347.45

    Ref: TM-T26894

  • TC-G 24
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    TC-G 24

    CAS:
    <p>GSK-3β inhibitor</p>
    Formula:C15H11ClN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:330.73

    Ref: TM-T23436

  • Cazpaullone
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    Cazpaullone

    CAS:
    <p>Cazpaullone inhibits GSK-3 and briefly boosts Pax4 mRNA expression.</p>
    Formula:C16H10N4O
    Color and Shape:Solid
    Molecular weight:274.28

    Ref: TM-T26959

  • VP3.15
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    VP3.15

    CAS:
    <p>VP3.15 is an orally bioavailable and CNS-penetrant dual inhibitor of phosphodiesterase (PDE)7- GSK3 (IC50s: 1.59 μM and 0.88 μM for PDE7 and GSK-3).</p>
    Formula:C20H22N4OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:366.48

    Ref: TM-T13310

  • BRD1652
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    BRD1652

    CAS:
    <p>BRD1652 is a highly selective and potent GSK3 inhibitor.</p>
    Formula:C20H20F3N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:375.39

    Ref: TM-T26896

  • ZDWX-25
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    ZDWX-25

    CAS:
    <p>ZDWX-25, a strong GSK-3β &amp; DYRK1A inhibitor, kills SH-SY5Y/HL-7702 cells, may aid Alzheimer's research; IC50: 71 nM for GSK-3β.</p>
    Formula:C17H15N3O3
    Color and Shape:Solid
    Molecular weight:309.32

    Ref: TM-T60748

  • PfGSK3/PfPK6-IN-2
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    PfGSK3/PfPK6-IN-2

    CAS:
    <p>PfGSK3/PfPK6-IN-2 inhibits Plasmodium falciparum GSK3/PK6 (IC50: 172 nM/11 nM) for Malaria research.</p>
    Formula:C24H25Cl2N5OS
    Color and Shape:Solid
    Molecular weight:502.46

    Ref: TM-T72629

  • PIMPC
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    PIMPC

    CAS:
    <p>PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibits</p>
    Formula:C21H19N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:357.41

    Ref: TM-T79693

  • 3F8
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    3F8

    CAS:
    <p>3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used in</p>
    Formula:C15H14N2O4
    Purity:98.14% - 98.25%
    Color and Shape:Solid
    Molecular weight:286.28

    Ref: TM-T22180

  • TCS 2002
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    TCS 2002

    CAS:
    <p>GSK-3β inhibitor 9b: potent, selective, oral, IC50=35 nM, good pharmacokinetics, BBB-permeable, researched for Alzheimer's.</p>
    Formula:C18H14N2O3S
    Color and Shape:Solid
    Molecular weight:338.38

    Ref: TM-T22157

  • GSK-3β inhibitor 12
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    GSK-3β inhibitor 12

    CAS:
    <p>GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3β</p>
    Formula:C14H13N3OS
    Purity:98.58%
    Color and Shape:Solid
    Molecular weight:271.34

    Ref: TM-T60472

  • Aloisine B
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    Aloisine B

    CAS:
    <p>Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.</p>
    Formula:C15H14ClN3
    Purity:95.15%
    Color and Shape:Solid
    Molecular weight:271.74

    Ref: TM-T69188