gsk-3
GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.
Found 110 products for "gsk-3".
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PIMPC
CAS:PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibitsFormula:C21H19N5OPurity:98%Color and Shape:SolidMolecular weight:357.41BRD0209
CAS:BRD0209 is a highly selective and potent GSK3 inhibitor.Formula:C22H25N3OPurity:99.92%Color and Shape:SolidMolecular weight:347.4534GSK-3β inhibitor 22
CAS:GSK-3β inhibitor22 (compound 20o) is a GSK-3β inhibitor with an IC50 of 3.1 nM, showing potential for Alzheimer's disease research.Formula:C18H12F3N3O2S2Color and Shape:SolidMolecular weight:423.43GSK-3β inhibitor 12
CAS:GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3βFormula:C14H13N3OSPurity:98.58%Color and Shape:Yellow SolidMolecular weight:271.338GSK-3β inhibitor 11
CAS:GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM.Formula:C20H15N3O4SPurity:97.4%Color and Shape:SolidMolecular weight:393.416GSK-3 Inhibitor XIII
CAS:GSK-3 InhibitorXIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.Formula:C18H15N5Purity:99.85% - 99.95%Color and Shape:SolidMolecular weight:301.3452BIP-135
CAS:BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor.Formula:C21H13BrN2O3Purity:99.93%Color and Shape:SolidMolecular weight:421.244GSK-3β inhibitor 2
CAS:GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50Formula:C14H14N4O3SPurity:99.08%Color and Shape:Yellow SolidMolecular weight:318.351PT-65
CAS:PT-65, a potent and selective GSK3 degrader, demonstrates the highest degradation capacity for GSK3α (DC50 = 28.3 nM) and GSK3β (DC50 = 34.2 nM) in SH-SY5Y cells, making it applicable for Alzheimer's disease research [1].Formula:C51H63N13O12SColor and Shape:SolidMolecular weight:1082.19SAR502250
CAS:SAR502250: potent, selective GSK3 inhibitor, IC50=12nM, oral, brain-penetrant, potential for AD research, antidepressant-like properties.Formula:C19H18FN5O2Color and Shape:SolidMolecular weight:367.3769TCS 21311
CAS:TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Formula:C27H25F3N4O4Purity:99.39% - ≥98%Color and Shape:SolidMolecular weight:526.515-Iodo-indirubin-3'-monoxime
CAS:5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50sFormula:C16H10IN3O2Color and Shape:SolidMolecular weight:403.174Antitrypanosomal agent 14
CAS:Antitrypanosomal agent 14 (Compound 1), a potent T.Formula:C14H23N3OSPurity:98%Color and Shape:SolidMolecular weight:281.42GSK-3β inhibitor 8
CAS:GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidineFormula:C20H20ClN5OSPurity:98.46%Color and Shape:SolidMolecular weight:413.92(Rac)-BRD0705
CAS:(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is an effective and selective inhibitor of GSK3α.Formula:C20H23N3OPurity:99.7%Color and Shape:SolidMolecular weight:321.4161A 1070722
CAS:A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, potential brain GSK-3 PET radiotracer.Formula:C17H13F3N4O2Purity:99.9%Color and Shape:White SolidMolecular weight:362.31BRD5648
CAS:BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.Formula:C20H23N3OPurity:99.89%Color and Shape:SolidMolecular weight:321.4161GSK-3 inhibitor 1
CAS:GSK-3 inhibitor 1 is a GSK-3 inhibitor.Formula:C22H17ClFN5O2Purity:98.42%Color and Shape:SolidMolecular weight:437.854IAB15
CAS:IAB15 is a selective GSK-3beta inhibitor; activates Wnt/beta-catenin signaling; neuroprotective and anti-proliferative; Parkinson's and cancer research.Formula:C15H14F3NO2Purity:99.25%Color and Shape:SolidMolecular weight:297.27GSK-3β inhibitor 7
GSK-3β inhibitor 7 is a GSK-3β inhibitor (IC50: 5.25 μM).Formula:C27H23BrN4O2SColor and Shape:SolidMolecular weight:547.47
