CymitQuimica logo
gsk-3

gsk-3

GSK-3 inhibitors are compounds that target Glycogen Synthase Kinase 3 (GSK-3), an enzyme involved in numerous cellular processes, including glycogen metabolism, gene transcription, and cell proliferation. GSK-3 is implicated in various diseases, such as diabetes, neurodegenerative disorders, and cancer. Inhibitors of GSK-3 are important tools for exploring these pathways and developing potential therapies. At CymitQuimica, we provide GSK-3 inhibitors to support your research in metabolic diseases, neurobiology, and oncology.

Found 112 products of "gsk-3"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • GSK3-IN-2
    Targetmol
    + Info

    GSK3-IN-2

    CAS:
    <p>GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.</p>
    Formula:C17H19N3OS
    Purity:98.8%
    Color and Shape:Solid
    Molecular weight:313.42

    Ref: TM-T73270

  • BRD3731
    Targetmol
    + Info

    BRD3731

    CAS:
    <p>BRD3731 selectively inhibits GSK3β with IC50 of 15 nM; it's promising for PTSD, psychiatric issues, diabetes, and neurodegeneration.</p>
    Formula:C24H31N3O
    Color and Shape:Solid
    Molecular weight:377.52

    Ref: TM-T61578

  • 18BIOder
    Targetmol
    + Info

    18BIOder

    CAS:
    <p>18BIOder is a neuroprotective inhibitor of GSK-3β, highly selectively inhibiting HIV-1. It is the second generation derivative of 6BIO.</p>
    Formula:C9H7ClN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:210.62

    Ref: TM-T24969

  • MRT80
    Targetmol
    + Info

    MRT80

    CAS:
    <p>MRT80 is an inhibitor of GSK-3 in vitro. MRT80 de-stabilizes MDM2 and stabilizes p53 protein and E2F-1.</p>
    Formula:C15H15N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.31

    Ref: TM-T28108

  • DIF-3
    Targetmol
    + Info

    DIF-3

    CAS:
    <p>DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.</p>
    Formula:C13H17ClO4
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:272.72

    Ref: TM-T60485

  • EHT 1610
    Targetmol
    + Info

    EHT 1610

    CAS:
    <p>EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.</p>
    Formula:C18H14FN5O2S
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T15204

  • ARN25068
    Targetmol
    + Info

    ARN25068

    CAS:
    <p>ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.</p>
    Formula:C19H18N6S
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:362.45

    Ref: TM-T61360

  • GSK-3β inhibitor 2
    Targetmol
    + Info

    GSK-3β inhibitor 2

    CAS:
    <p>GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50</p>
    Formula:C14H14N4O3S
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:318.35

    Ref: TM-T11471

  • BIP-135
    Targetmol
    + Info

    BIP-135

    CAS:
    <p>BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor.</p>
    Formula:C21H13BrN2O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:421.24

    Ref: TM-T14613

  • GSK-3 Inhibitor XIII
    Targetmol
    + Info

    GSK-3 Inhibitor XIII

    CAS:
    <p>GSK-3 InhibitorXIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.</p>
    Formula:C18H15N5
    Purity:99.85% - 99.86%
    Color and Shape:Solid
    Molecular weight:301.35

    Ref: TM-T78578

  • ABC1183
    Targetmol
    + Info

    ABC1183

    CAS:
    <p>ABC1183, an oral diaminothiazole, inhibits GSK3α/β, CDK9, hinders cancer cell growth, induces G2/M arrest, and modulates phosphorylation.</p>
    Formula:C18H14N4OS
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:334.39

    Ref: TM-T23601

  • GSK-3β inhibitor 11
    Targetmol
    + Info

    GSK-3β inhibitor 11

    CAS:
    <p>GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM.</p>
    Formula:C20H15N3O4S
    Purity:97.33%
    Color and Shape:Solid
    Molecular weight:393.42

    Ref: TM-T61809

  • BRD5648
    Targetmol
    + Info

    BRD5648

    CAS:
    <p>BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.</p>
    Formula:C20H23N3O
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:321.42

    Ref: TM-T10608

  • PT-65
    Targetmol
    + Info

    PT-65

    CAS:
    <p>PT-65, a potent and selective GSK3 degrader, demonstrates the highest degradation capacity for GSK3α (DC50 = 28.3 nM) and GSK3β (DC50 = 34.2 nM) in SH-SY5Y cells, making it applicable for Alzheimer's disease research [1].</p>
    Formula:C51H63N13O12S
    Color and Shape:Solid
    Molecular weight:1082.19

    Ref: TM-T84913

  • Antitrypanosomal agent 14
    Targetmol
    + Info

    Antitrypanosomal agent 14

    CAS:
    <p>Antitrypanosomal agent 14 (Compound 1), a potent T.</p>
    Formula:C14H23N3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.42

    Ref: TM-T79254

  • SAR502250
    Targetmol
    + Info

    SAR502250

    CAS:
    <p>SAR502250: potent, selective GSK3 inhibitor, IC50=12nM, oral, brain-penetrant, potential for AD research, antidepressant-like properties.</p>
    Formula:C19H18FN5O2
    Color and Shape:Solid
    Molecular weight:367.38

    Ref: TM-T35560

  • GSK-3β inhibitor 8
    Targetmol
    + Info

    GSK-3β inhibitor 8

    CAS:
    <p>GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine</p>
    Formula:C20H20ClN5OS
    Purity:98.46%
    Color and Shape:Solid
    Molecular weight:413.92

    Ref: TM-T35556

  • (Rac)-BRD0705
    Targetmol
    + Info

    (Rac)-BRD0705

    CAS:
    <p>(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is an effective and selective inhibitor of GSK3α.</p>
    Formula:C20H23N3O
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:321.42

    Ref: TM-T12664

  • A 1070722
    Targetmol
    + Info

    A 1070722

    CAS:
    <p>A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, potential brain GSK-3 PET radiotracer.</p>
    Formula:C17H13F3N4O2
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:362.31

    Ref: TM-T10202

  • TCS 21311
    Targetmol
    + Info

    TCS 21311

    CAS:
    <p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ &amp; GSK3β; &gt;100x selective over JAK1, JAK2, TYK2.</p>
    Formula:C27H25F3N4O4
    Purity:99.39% - ≥98%
    Color and Shape:Solid
    Molecular weight:526.51

    Ref: TM-T17019