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AMPK

AMPK

AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.

Found 158 products of "AMPK"

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  • Teneligliptin hydrobromide

    CAS:
    <p>Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.</p>
    Formula:C22H30N6OSBrH
    Purity:97.83% - 99.92%
    Color and Shape:Solid
    Molecular weight:628.86
  • Flurbiprofen Axetil

    CAS:
    <p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>
    Formula:C19H19FO4
    Purity:97.58% - 98%
    Color and Shape:Solid
    Molecular weight:330.35
  • STF-118804

    CAS:
    <p>STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 &lt;10 nM.</p>
    Formula:C25H23N3O4S
    Purity:98.66%
    Color and Shape:Solid
    Molecular weight:461.53
  • SBI-0206965

    CAS:
    <p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>
    Formula:C21H21BrN4O5
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:489.32
  • WZ4003

    CAS:
    <p>WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.</p>
    Formula:C25H29ClN6O3
    Purity:99.65% - >99.99%
    Color and Shape:Solid
    Molecular weight:496.99
  • GSK-690693

    CAS:
    <p>GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.</p>
    Formula:C21H27N7O3
    Purity:98.07% - 99.77%
    Color and Shape:Solid
    Molecular weight:425.48
  • RSVA405

    CAS:
    <p>RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor</p>
    Formula:C17H20N4O2
    Purity:99.30%
    Color and Shape:Solid
    Molecular weight:312.37
  • Nepodin

    CAS:
    <p>Nepodin exhibits antimalarial, anti-inflammatory, and antidiabetic effects by inhibiting COX and activating AMPK to stimulate GLUT4.</p>
    Formula:C13H12O3
    Purity:98.5% - 99.12%
    Color and Shape:Solid
    Molecular weight:216.23
  • PKC-iota inhibitor 1

    CAS:
    <p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>
    Formula:C21H22N6O
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:374.44
  • ON123300

    CAS:
    <p>ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).</p>
    Formula:C24H27N7O
    Purity:99.22% - 99.53%
    Color and Shape:Solid
    Molecular weight:429.52
  • [6]-Gingerol

    CAS:
    <p>[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.</p>
    Formula:C17H26O4
    Purity:98% - 99.66%
    Color and Shape:Light Yellow Oiliness
    Molecular weight:294.39
  • Palmitelaidic Acid

    CAS:
    <p>Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.</p>
    Formula:C16H30O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:254.41
  • YKL-06-061

    CAS:
    <p>YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.</p>
    Formula:C30H37N7O2
    Purity:99.52% - 99.79%
    Color and Shape:Solid
    Molecular weight:527.66
  • Tizoxanide

    CAS:
    <p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>
    Formula:C10H7N3O4S
    Purity:98.89% - 99.28%
    Color and Shape:Solid
    Molecular weight:265.25
  • Kudinoside D

    CAS:
    <p>Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.</p>
    Formula:C47H72O17
    Purity:99.66% - 99.88%
    Color and Shape:Solid
    Molecular weight:909.06
  • Annaosanchun

    CAS:
    <p>Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).</p>
    Formula:C19H32O3
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:308.46
  • ASP4132

    CAS:
    <p>ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.</p>
    Formula:C46H51F3N6O8S2
    Purity:98.34%
    Color and Shape:Solid
    Molecular weight:937.06
  • HTH-01-015

    CAS:
    <p>HTH-01-015 is a selective NUAK1 inhibitor (IC50=100 nM).</p>
    Formula:C26H28N8O
    Purity:98.38% - 99.70%
    Color and Shape:Solid
    Molecular weight:468.55
  • Buformin hydrochloride

    CAS:
    <p>Buformin hydrochloride, an oral biguanide antidiabetic, activates AMPK, enhances insulin sensitivity, and inhibits hepatic glucose production.</p>
    Formula:C6H16ClN5
    Purity:97.83%
    Color and Shape:Solid
    Molecular weight:193.68
  • PF-06409577

    CAS:
    <p>PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).</p>
    Formula:C19H16ClNO3
    Purity:95.17% - 98.21%
    Color and Shape:Solid
    Molecular weight:341.79