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AMPK

AMPK

AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.

Found 168 products of "AMPK"

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  • WZ4003
    Targetmol
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    WZ4003

    CAS:
    <p>WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.</p>
    Formula:C25H29ClN6O3
    Purity:99.65% - >99.99%
    Color and Shape:Solid
    Molecular weight:496.99

    Ref: TM-T6291

  • Marein
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    Marein

    CAS:
    Marein prevents PC12 cell damage by protecting mitochondria and activating AMPK, potentially countering diabetic encephalopathy.
    Formula:C21H22O11
    Purity:99.12% - 99.84%
    Color and Shape:Solid
    Molecular weight:450.39

    Ref: TM-TN1911

  • Daphnetin
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    Daphnetin

    CAS:
    <p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>
    Formula:C9H6O4
    Purity:97.47% - 99.8%
    Color and Shape:Solid
    Molecular weight:178.14

    Ref: TM-T2851

  • Dorsomorphin
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    Dorsomorphin

    CAS:
    Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.
    Formula:C24H25N5O
    Purity:98% - 99.06%
    Color and Shape:Solid
    Molecular weight:399.49

    Ref: TM-T1977

  • Bempedoic acid
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    Bempedoic acid

    CAS:
    <p>Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.</p>
    Formula:C19H36O5
    Purity:99.85% - 99.94%
    Color and Shape:Solid
    Molecular weight:344.49

    Ref: TM-T3625

  • Mogroside I E1
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    Mogroside I E1

    CAS:
    Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.
    Formula:C36H62O9
    Purity:98.62% - 99.71%
    Color and Shape:Solid
    Molecular weight:638.87

    Ref: TM-T12090

  • Teneligliptin hydrobromide
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    Teneligliptin hydrobromide

    CAS:
    Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.
    Formula:C22H30N6OSBrH
    Purity:97.83% - 99.92%
    Color and Shape:Solid
    Molecular weight:628.86

    Ref: TM-T6999

  • Flurbiprofen Axetil
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    Flurbiprofen Axetil

    CAS:
    Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.
    Formula:C19H19FO4
    Purity:97.58% - 98%
    Color and Shape:Solid
    Molecular weight:330.35

    Ref: TM-T3500

  • STF-118804
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    STF-118804

    CAS:
    STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.
    Formula:C25H23N3O4S
    Purity:98.66%
    Color and Shape:Solid
    Molecular weight:461.53

    Ref: TM-T6682

  • SBI-0206965
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    SBI-0206965

    CAS:
    <p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>
    Formula:C21H21BrN4O5
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:489.32

    Ref: TM-T2128

  • Gomisin J
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    Gomisin J

    CAS:
    Gomisin J is a natural product and have vasodilatory activity.
    Formula:C22H28O6
    Purity:99.59% - 99.60%
    Color and Shape:Solid
    Molecular weight:388.45

    Ref: TM-T3904

  • GSK-690693
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    GSK-690693

    CAS:
    GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
    Formula:C21H27N7O3
    Purity:98.07% - 99.77%
    Color and Shape:Solid
    Molecular weight:425.48

    Ref: TM-T6285

  • RSVA405
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    RSVA405

    CAS:
    RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor
    Formula:C17H20N4O2
    Purity:99.30%
    Color and Shape:Solid
    Molecular weight:312.37

    Ref: TM-T8476

  • Nepodin
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    Nepodin

    CAS:
    Nepodin exhibits antimalarial, anti-inflammatory, and antidiabetic effects by inhibiting COX and activating AMPK to stimulate GLUT4.
    Formula:C13H12O3
    Purity:97.9% - 99.12%
    Color and Shape:Solid
    Molecular weight:216.23

    Ref: TM-TN1100

  • PKC-iota inhibitor 1
    Targetmol
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    PKC-iota inhibitor 1

    CAS:
    <p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>
    Formula:C21H22N6O
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:374.44

    Ref: TM-T8764

  • MRT67307 HCl (1190378-57-4(free base))
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    MRT67307 HCl (1190378-57-4(free base))

    MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).
    Formula:C26H37ClN6O2
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:501.07

    Ref: TM-T5162

  • ON123300
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    ON123300

    CAS:
    ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
    Formula:C24H27N7O
    Purity:99.53% - 99.7%
    Color and Shape:Solid
    Molecular weight:429.52

    Ref: TM-T6920

  • Metformin glycinate
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    Metformin glycinate

    CAS:
    Metformin glycinate activates AMPK, enhances insulin sensitivity, and reduces glucose absorption for better glycemic control.
    Formula:C6H16N6O2
    Color and Shape:Solid
    Molecular weight:204.23

    Ref: TM-T71222

  • [6]-Gingerol
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    [6]-Gingerol

    CAS:
    [6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.
    Formula:C17H26O4
    Purity:98% - 99.66%
    Color and Shape:Light Yellow Oiliness
    Molecular weight:294.39

    Ref: TM-T3405

  • Palmitelaidic Acid
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    Palmitelaidic Acid

    CAS:
    Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.
    Formula:C16H30O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:254.41

    Ref: TM-T19500