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PI3K

PI3K

PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.

Found 242 products of "PI3K"

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  • PI3K-IN-6
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    PI3K-IN-6

    CAS:
    <p>PI3K-IN-6 is an oral active and highly selective inhibitor of phosphoinositide 3-kinase (PI3K) β/δ(IC50 values of 7.8 nM/5.3 nM , respectively).</p>
    Formula:C17H14Cl2FN9O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:450.26

    Ref: TM-T12457

  • PI3Kα-IN-13
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    PI3Kα-IN-13

    CAS:
    <p>PI3Kα-IN-13 (Compound 18a), a PI3Kα inhibitor with an IC50 of 2.5 nM, effectively induces apoptosis and hampers the proliferation of various cancer cell lines,</p>
    Formula:C21H19N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:389.41

    Ref: TM-T79685

  • PI4KIII β inhibitor 3
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    PI4KIII β inhibitor 3

    CAS:
    <p>PI4KIII beta inhibitor 3 is a novel and high effective inhibitor of PI4KIIIβ (IC50 of 5.7 nM).</p>
    Formula:C22H22N8OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:446.53

    Ref: TM-T12467

  • CAL-130 Hydrochloride
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    CAL-130 Hydrochloride

    CAS:
    <p>CAL-130 Hydrochloride is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).</p>
    Formula:C23H23ClN8O
    Color and Shape:Solid
    Molecular weight:462.94

    Ref: TM-T10660L

  • AZD3458
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    AZD3458

    CAS:
    <p>AZD3458 is a potent and remarkably selective inhibitor of PI3Kγ (PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ with pIC50s of 9.1, 5.1, &lt;4.5, and 6.5 , respectively).</p>
    Formula:C20H23N3O4S2
    Color and Shape:Solid
    Molecular weight:433.54

    Ref: TM-T12466

  • PI3K-IN-10
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    PI3K-IN-10

    CAS:
    <p>PI3K-IN-10 is a potent inhibitor of pan-PI3K .</p>
    Formula:C23H19ClN6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.89

    Ref: TM-T12456

  • PI3Kα/mTOR-IN-1
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    PI3Kα/mTOR-IN-1

    CAS:
    <p>PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR.</p>
    Formula:C16H18N6O
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:310.35

    Ref: TM-T12589

  • PI3Kγ inhibitor 1
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    PI3Kγ inhibitor 1

    CAS:
    <p>PI3Kγ inhibitor 1 is a inhibitor of PI3Kδ and PI3Kγ.</p>
    Formula:C32H26N8O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:586.67

    Ref: TM-T12464

  • ON 146040
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    ON 146040

    CAS:
    <p>ON 146040 is an effective inhibitor of PI3K isoforms with IC50s of 14 and 20 nM for PI3Kα and PI3Kδ, respectively.</p>
    Formula:C24H23N7O3S
    Purity:97.39%
    Color and Shape:Solid
    Molecular weight:489.55

    Ref: TM-T12310

  • PI3K-IN-38
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    PI3K-IN-38

    CAS:
    <p>PI3K-IN-38: oral PI3K inhibitor, IC50 of 0.541 µM, anticancer, anti-inflammatory, halts tumors in vivo.</p>
    Formula:C20H24N6O2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:380.44

    Ref: TM-T61618

  • CHMFL-PI3KD-317
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    CHMFL-PI3KD-317

    CAS:
    <p>CHMFL-PI3KD-317: potent PI3Kδ inhibitor, IC50=6 nM, orally active, &gt;10x selective vs. PI3K isoforms, anti-cancer.</p>
    Formula:C21H24ClN5O3S2
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:494.03

    Ref: TM-T10804

  • AZ044
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    AZ044

    CAS:
    <p>AZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).</p>
    Formula:C24H27N3O3S
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:437.55

    Ref: TM-T26698

  • TGX-115
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    TGX-115

    CAS:
    <p>TGX-115 inhibits PI 3-K p110β (IC50=0.13μM) &amp; p110δ (IC50=0.63μM), treats various cardiovascular diseases.</p>
    Formula:C20H20N2O3
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:336.38

    Ref: TM-T24873

  • SRX3207
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    SRX3207

    CAS:
    <p>SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.</p>
    Formula:C29H29N7O3S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:555.65

    Ref: TM-T22430

  • PQR514
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    PQR514

    CAS:
    <p>PQR514: more potent pan-PI3K inhibitor than predecessor PQR309, exhibits strong anticancer activity in vitro and in OVCAR-3 model.</p>
    Formula:C16H20F2N8O2
    Purity:98.77% - 99.19%
    Color and Shape:Solid
    Molecular weight:394.38

    Ref: TM-T70058

  • GS-9901
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    GS-9901

    CAS:
    <p>GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.</p>
    Formula:C22H17ClFN9O
    Purity:98.60% - 99.92%
    Color and Shape:Solid
    Molecular weight:477.88

    Ref: TM-T15420

  • NVP-BAG956
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    NVP-BAG956

    CAS:
    <p>NVP-BAG956 is an ATP-competitive PI3K inhibitor (IC50s: 34/56/112/444 nM for PI3Kδ/PI3Kα/PI3Kγ/PI3Kβ).</p>
    Formula:C28H21N5
    Purity:99.25% - 99.80%
    Color and Shape:Solid
    Molecular weight:427.5

    Ref: TM-TQ0313

  • PI3Kγ inhibitor 2
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    PI3Kγ inhibitor 2

    CAS:
    <p>PI3Kγ inhibitor 2 is an orally bioavailable inhibitor of PI3Kγ(Ki of 4 nM).</p>
    Formula:C20H18F3N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.38

    Ref: TM-T12465

  • LAS191954
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    LAS191954

    CAS:
    <p>LAS191954 is a selective, potent and orally active PI3Kδ inhibitor for inflammatory diseases treatment(IC50 : 2.6 nM).</p>
    Formula:C20H15N9O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:397.39

    Ref: TM-T11818

  • Ginsenoside Rk1
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    Ginsenoside Rk1

    CAS:
    <p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>
    Formula:C42H70O12
    Purity:98.46% - 99.13%
    Color and Shape:Solid
    Molecular weight:767

    Ref: TM-T4S1499