PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 241 products of "PI3K"
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FD2056
CAS:<p>FD2056 is a potent, orally active PI3K inhibitor, with IC50 values of 0.30, 0.80, 1.10, and 0.42 nM against PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ, respectively.</p>Formula:C23H17ClN6O2SPurity:98%Color and Shape:SolidMolecular weight:476.94PI3K-IN-9
CAS:<p>PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM).</p>Formula:C19H23N7OPurity:98%Color and Shape:SolidMolecular weight:365.43PI4KIII β inhibitor 3
CAS:PI4KIII beta inhibitor 3 is a novel and high effective inhibitor of PI4KIIIβ (IC50 of 5.7 nM).Formula:C22H22N8OSPurity:98%Color and Shape:SolidMolecular weight:446.53Nemiralisib
CAS:<p>Nemiralisib (GSK-2269557) is an oral PI3Kδ inhibitor (pKi 9.9) for treating respiratory diseases like COPD.</p>Formula:C26H28N6OPurity:99.91%Color and Shape:SolidMolecular weight:440.54PI3Kγ inhibitor 1
CAS:<p>PI3Kγ inhibitor 1 is a inhibitor of PI3Kδ and PI3Kγ.</p>Formula:C32H26N8O2SPurity:98%Color and Shape:SolidMolecular weight:586.67PI3K/mTOR Inhibitor-2
CAS:<p>Potent PI3K/mTOR Inhibitor-2 targets PI3Kα/β/δ/γ & mTOR (IC50: 3.4, 34, 16,1, 4.7 nM); exhibits antitumor effects.</p>Formula:C20H13ClF2N4O4SPurity:96.16%Color and Shape:SolidMolecular weight:478.86PI3Kγ inhibitor 7
CAS:<p>PI3Kγ Inhibitor 7 (compound 2) is a potent, orally active agent that selectively inhibits PI3Kγ with an IC50 of 3.42 nM and demonstrates antitumor activity [1].</p>Formula:C31H25N9O2Purity:98%Color and Shape:SolidMolecular weight:555.59PI3Kα/mTOR-IN-1
CAS:<p>PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR.</p>Formula:C16H18N6OPurity:99.89%Color and Shape:SolidMolecular weight:310.35CAL-130
CAS:CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Formula:C23H22N8OPurity:98%Color and Shape:SolidMolecular weight:426.47CHMFL-PI3KD-317
CAS:<p>CHMFL-PI3KD-317: potent PI3Kδ inhibitor, IC50=6 nM, orally active, >10x selective vs. PI3K isoforms, anti-cancer.</p>Formula:C21H24ClN5O3S2Purity:99.16%Color and Shape:SolidMolecular weight:494.03NVP-BAG956
CAS:NVP-BAG956 is an ATP-competitive PI3K inhibitor (IC50s: 34/56/112/444 nM for PI3Kδ/PI3Kα/PI3Kγ/PI3Kβ).Formula:C28H21N5Purity:99.25% - 99.80%Color and Shape:SolidMolecular weight:427.5PQR514
CAS:<p>PQR514: more potent pan-PI3K inhibitor than predecessor PQR309, exhibits strong anticancer activity in vitro and in OVCAR-3 model.</p>Formula:C16H20F2N8O2Purity:98.77% - 99.19%Color and Shape:SolidMolecular weight:394.38GS-9901
CAS:GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.Formula:C22H17ClFN9OPurity:98.60% - 99.92%Color and Shape:SolidMolecular weight:477.88AZ044
CAS:<p>AZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).</p>Formula:C24H27N3O3SPurity:99.5%Color and Shape:SolidMolecular weight:437.55TGX-115
CAS:<p>TGX-115 inhibits PI 3-K p110β (IC50=0.13μM) & p110δ (IC50=0.63μM), treats various cardiovascular diseases.</p>Formula:C20H20N2O3Purity:99.48%Color and Shape:SolidMolecular weight:336.38SRX3207
CAS:<p>SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.</p>Formula:C29H29N7O3SPurity:99.85%Color and Shape:SolidMolecular weight:555.65LAS191954
CAS:<p>LAS191954 is a selective, potent and orally active PI3Kδ inhibitor for inflammatory diseases treatment(IC50 : 2.6 nM).</p>Formula:C20H15N9OPurity:98%Color and Shape:SolidMolecular weight:397.39PIK-inhibitors
CAS:<p>PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.</p>Formula:C19H17N5O2Purity:96.98%Color and Shape:SolidMolecular weight:347.37PI3Kδ-IN-17
CAS:<p>PI3Kδ-IN-17 (Compound S5) is a potent PI3K δ inhibitor, exhibiting an IC50 value of 2.82 nM and demonstrates significant efficacy in suppressing the</p>Formula:C23H24F3N7O2Purity:98%Color and Shape:SolidMolecular weight:487.48SAR-260301
CAS:<p>SAR-260301 is an orally available and selective inhibitor of PI3Kβ (IC50: 23 nM).</p>Formula:C19H22N4O3Purity:99.74%Color and Shape:SolidMolecular weight:354.4
