PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
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Rigosertib sodium
CAS:592542-60-4
Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over …
Formula:
C21H24NNaO8S
Purity:
98% - 99.37%
Color and Shape:
Solid
Molecular weight:
473.47
Ref: TM-T5818
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 135.00 € | ||
| 100mg | 217.00 € | ||
| 200mg | 322.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Buparlisib
CAS:944396-07-0
Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: …
Formula:
C18H21F3N6O2
Purity:
95.32% - 98.4%
Color and Shape:
Solid
Molecular weight:
410.39
Ref: TM-T1827
| 5mg | 62.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 142.00 € | ||
| 200mg | 231.00 € | ||
| 500mg | 417.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Quercetin
CAS:117-39-5
Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.
Formula:
C15H10O7
Purity:
96.29% - 98.05%
Color and Shape:
Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)
Molecular weight:
302.24
Ref: TM-T2174
| 1g | 54.00 € | ||
| 5g | 85.00 € | ||
| 10mg | 52.00 € | ||
| 500mg | 49.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
MOMIPP
CAS:1363421-46-8
MOMIPP: PIKfyve inhibitor, spurs macropinocytosis, crosses blood-brain barrier, curbs glioblastoma growth.
Formula:
C18H16N2O2
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
292.33
Ref: TM-T33467
| 1mg | 112.00 € | ||
| 5mg | 154.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 438.00 € | ||
| 50mg | 605.00 € | ||
| 100mg | 907.00 € | ||
| 1mL*10mM (DMSO) | 243.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
(+)-Nortrachelogenin
CAS:61521-74-2
(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.
Formula:
C20H22O7
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
374.38
Ref: TM-TN4673
| 1mg | 126.00 € | ||
| 5mg | 302.00 € | ||
| 10mg | 436.00 € | ||
| 25mg | 646.00 € | ||
| 50mg | 906.00 € | ||
| 1mL*10mM (DMSO) | 312.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Samotolisib
CAS:1386874-06-1
Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.
Formula:
C23H26N4O3
Purity:
98.41% - 99.69%
Color and Shape:
Solid
Molecular weight:
406.48
Ref: TM-T6883
| 5mg | 48.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 368.00 € | ||
| 200mg | 523.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Heterophyllin B
CAS:145459-19-4
Heterophyllin B hinders esophageal cancer cell adhesion/invasion via PI3K/AKT/β-catenin and gene regulation.
Formula:
C40H58N8O8
Purity:
99.12% - 99.55%
Color and Shape:
Solid
Molecular weight:
778.94
Ref: TM-T4S1796
| 1mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 342.00 € | ||
| 100mg | 504.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AMG319
CAS:1608125-21-8
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity …
Formula:
C21H16FN7
Purity:
98.57% - 98.9%
Color and Shape:
Crystalline Solid
Molecular weight:
385.4
Ref: TM-T6757
| 2mg | 49.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 225.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 554.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
P7C3-A20
CAS:1235481-90-9
P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity.
Formula:
C22H19Br2FN2O
Purity:
96.83% - ≥98%
Color and Shape:
Solid
Molecular weight:
506.21
Ref: TM-T2423
| 5mg | 34.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 62.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 149.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Voxtalisib
CAS:934493-76-2
Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 …
Formula:
C13H14N6O
Purity:
98.01% - 99.36%
Color and Shape:
Solid
Molecular weight:
270.29
Ref: TM-T7014
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 380.00 € | ||
| 100mg | 552.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Umbralisib
CAS:1532533-67-7
Umbralisib (TGR 1202) is a PI3Kδ inhibitor.
Formula:
C31H24F3N5O3
Purity:
99.56% - 99.83%
Color and Shape:
White Solid
Molecular weight:
571.55
Ref: TM-T4976
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 335.00 € | ||
| 50mg | 440.00 € | ||
| 100mg | 644.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AZD-8835
CAS:1620576-64-8
AZD-8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ …
Formula:
C22H31N9O3
Purity:
98.22% - 98.49%
Color and Shape:
Solid
Molecular weight:
469.54
Ref: TM-T6774
| 5mg | 50.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 166.00 € | ||
| 100mg | 293.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AS-604850
CAS:648449-76-7
AS-604850: ATP-competitive PI3Kγ inhibitor, IC50 250 nM, 18x >PI3Kα, 80x > PI3Kδ/β.
Formula:
C11H5F2NO4S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
285.22
Ref: TM-T6394
| 10mg | 50.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 203.00 € | ||
| 200mg | 301.00 € | ||
| 1mL*10mM (DMSO) | 37.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
PIK-93
CAS:593960-11-3
PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα …
Formula:
C14H16ClN3O4S2
Purity:
97.72%
Color and Shape:
Solid
Molecular weight:
389.88
Ref: TM-T2616
| 1mg | 44.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 515.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
CH5132799
CAS:1007207-67-1
CH5132799 has been used in trials studying the treatment of Solid Tumors.
Formula:
C15H19N7O3S
Purity:
98.81% - 99.87%
Color and Shape:
Solid
Molecular weight:
377.42
Ref: TM-T2619
| 1mg | 63.00 € | ||
| 2mg | 96.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 615.00 € | ||
| 100mg | 874.00 € | ||
| 500mg | 1,746.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Seletalisib
CAS:1362850-20-1
Seletalisib (UCB5857) (UCB5857) is a potent and specific PI3Kδ inhibitor (IC50: 12 nM).
Formula:
C23H14ClF3N6O
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
482.85
Ref: TM-TQ0044
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 468.00 € | ||
| 100mg | 656.00 € | ||
| 1mL*10mM (DMSO) | 125.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
α-Linolenic acid
CAS:463-40-1
α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and …
Formula:
C18H30O2
Purity:
98.19% - 99.81%
Color and Shape:
Physical Description Clear Colorless Liquid (Ntp 1992)
Molecular weight:
278.43
Ref: TM-T3P2904
| 50mg | 105.00 € | ||
| 100mg | 154.00 € | ||
| 500mg | 373.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
GSK2636771
CAS:1372540-25-4
GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid …
Formula:
C22H22F3N3O3
Purity:
98.58% - ≥95%
Color and Shape:
Solid
Molecular weight:
433.42
Ref: TM-T2073
| 1mg | 42.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 248.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 535.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Vps34-IN-1
CAS:1383716-33-3
Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.
Formula:
C21H24ClN7O
Purity:
97.04%
Color and Shape:
Solid
Molecular weight:
425.91
Ref: TM-T7015
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 493.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
SAR405
CAS:1523406-39-4
SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor …
Formula:
C19H21ClF3N5O2
Purity:
99.42% - 99.79%
Color and Shape:
Solid
Molecular weight:
443.85
Ref: TM-T12831L
| 1mg | 151.00 € | ||
| 2mg | 219.00 € | ||
| 5mg | 370.00 € | ||
| 10mg | 584.00 € | ||
| 25mg | 888.00 € | ||
| 50mg | 1,607.00 € | ||
| 1mL*10mM (DMSO) | 447.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
