PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 231 products of "PI3K"
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BGT226
CAS:BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Formula:C28H25F3N6O2Purity:95.74% - 99.78%Color and Shape:SolidMolecular weight:534.53Ref: TM-T6072L
1mg47.00€2mg62.00€5mg92.00€1mL*10mM (DMSO)107.00€10mg147.00€25mg295.00€50mg485.00€100mg737.00€NIH-12848
CAS:NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.Formula:C20H14F3N3SPurity:99.84% - 99.9%Color and Shape:SolidMolecular weight:385.41Ref: TM-T3556
2mg35.00€5mg51.00€1mL*10mM (DMSO)55.00€10mg75.00€25mg133.00€50mg225.00€100mg323.00€200mg447.00€GNE-493
CAS:GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM forFormula:C17H20N6O2SPurity:98%Color and Shape:SolidMolecular weight:372.44Rigosertib sodium
CAS:Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.Formula:C21H24NNaO8SPurity:98% - 99.37%Color and Shape:SolidMolecular weight:473.47SKI V
CAS:SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM),
Formula:C15H10O4Purity:98.78%Color and Shape:SolidMolecular weight:254.24Erucic acid
CAS:Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ).Formula:C22H42O2Purity:99.64%Color and Shape:Needles From Alcohol Liquid OthersolidMolecular weight:338.57PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formula:C19H16N4O3Purity:97.79% - 99.3%Color and Shape:SolidMolecular weight:348.36AS-252424
CAS:AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.Formula:C14H8FNO4SPurity:99.06% - 99.09%Color and Shape:SolidMolecular weight:305.28Ref: TM-T6208
1mg37.00€2mg52.00€5mg77.00€1mL*10mM (DMSO)84.00€10mg128.00€25mg205.00€50mg309.00€100mg447.00€500mg973.00€3-Methyladenine
CAS:3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).Formula:C6H7N5Purity:98% - 99.51%Color and Shape:SolidMolecular weight:149.15PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48Ref: TM-T6251
1mg34.00€2mg43.00€5mg63.00€1mL*10mM (DMSO)65.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€Deoxyelephantopin
CAS:Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.Formula:C19H20O6Purity:99.6% - 99.71%Color and Shape:SolidMolecular weight:344.36GDC0084
CAS:GDC0084 (RG7666) is a PI3K inhibitor with potential antineoplastic activity.
Formula:C18H22N8O2Purity:99.72% - 99.87%Color and Shape:SolidMolecular weight:382.42PIK-294
CAS:PIK-294 is a excellently specific p110δ inhibitor(IC50=10 nM).Formula:C28H23N7O2Purity:97.22% - >99.99%Color and Shape:SolidMolecular weight:489.53PF-4989216
CAS:PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Formula:C18H13FN6OSPurity:99.85%Color and Shape:SolidMolecular weight:380.4Ref: TM-T6938
2mg37.00€5mg62.00€1mL*10mM (DMSO)64.00€10mg96.00€25mg177.00€50mg311.00€100mg376.00€200mg535.00€Wortmannin
CAS:Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.Formula:C23H24O8Purity:95.84% - 99.77%Color and Shape:White SolidMolecular weight:428.43Ref: TM-T6283
1mg35.00€2mg50.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg113.00€25mg224.00€50mg385.00€100mg570.00€1-Deoxynojirimycin
CAS:1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.Formula:C6H13NO4Purity:99.65% - 99.98%Color and Shape:White-Beige Solid CrystallineMolecular weight:163.17Ref: TM-T3675
2mg43.00€1mL*10mM (DMSO)57.00€5mg58.00€10mg74.00€25mg140.00€50mg248.00€100mg321.00€500mg773.00€Eganelisib
CAS:Eganelisib (IPI-549) is an inhibitor of PI3Kγ (IC50 = 16, 3,200, 3,500, and >8,400 nM for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively)Formula:C30H24N8O2Purity:98.92% - 99.28%Color and Shape:SolidMolecular weight:528.56AMG 511
CAS:AMG 511: oral class I PI3K inhibitor (α, β, δ, γ Kis: 4, 6, 2, 1 nM), anti-tumor in mouse glioblastoma model, reduces p-Akt (Ser473).Formula:C22H28FN9O3SPurity:≥98%Color and Shape:SolidMolecular weight:517.58(E)-Akt inhibitor-IV
CAS:(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt.Formula:C31H29IN4SPurity:99.74% - 99.9%Color and Shape:SolidMolecular weight:616.56Ref: TM-T9393
1mg52.00€5mg110.00€1mL*10mM (DMSO)148.00€10mg170.00€25mg319.00€50mg444.00€100mg620.00€200mg875.00€iMDK
CAS:iMDK quarterhydrate, a PI3K inhibitor, blocks MDK growth factor and enhances NSCLC treatment with MEK inhibitors, sparing normal cells.Formula:C21H13FN2O2SPurity:99.99%Color and Shape:SolidMolecular weight:376.4
