mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Found 163 products of "mTOR"
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S6K1-IN-DG2
CAS:S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.Formula:C16H17BrN6OPurity:99.99%Color and Shape:SolidMolecular weight:389.25Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formula:C25H17F2N5O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:505.5Apitolisib
CAS:Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).Formula:C23H30N8O3SPurity:98.28% - 99.64%Color and Shape:SolidMolecular weight:498.6Torin 1
CAS:Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.Formula:C35H28F3N5O2Purity:98.3% - 99.33%Color and Shape:SolidMolecular weight:607.62NV-5138 hydrochloride
NV-5138 hydrochloride: a leucine analog, oral brain mTORC1 activator via Sestrin2, for antidepressant research.Formula:C7H14ClF2NO2Color and Shape:SolidMolecular weight:217.64mTOR inhibitor-1
CAS:C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formula:C16H15BrN2O3Purity:99.43%Color and Shape:SolidMolecular weight:363.21G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purity:97.3%Color and Shape:SolidMolecular weight:383.39Ref: TM-T8742
1mg35.00€5mg71.00€10mg96.00€25mg172.00€50mg248.00€100mg348.00€200mg470.00€1mL*10mM (DMSO)78.00€PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48Ref: TM-T6251
1mg34.00€2mg43.00€5mg63.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€1mL*10mM (DMSO)65.00€AZD-8055
CAS:AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.
Formula:C25H31N5O4Purity:98% - 99.69%Color and Shape:SolidMolecular weight:465.54Mito-LND
CAS:Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Formula:C43H45BrCl2N3OPPurity:97.25% - 98.34%Color and Shape:SolidMolecular weight:801.62Bimiralisib
CAS:Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity.Formula:C17H20F3N7O2Purity:97.58% - 98.92%Color and Shape:SolidMolecular weight:411.38Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formula:C22H28N2O4Purity:96.83% - 99.93%Color and Shape:SolidMolecular weight:384.47Salidroside
CAS:Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.Formula:C14H20O7Purity:97.81%Color and Shape:Red-Brown Fine PowderMolecular weight:300.30Ref: TM-T2717
2mg34.00€5mg50.00€10mg81.00€25mg130.00€50mg178.00€100mg268.00€200mg408.00€1mL*10mM (DMSO)55.00€OSI-027
CAS:OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Formula:C21H22N6O3Purity:97.42%Color and Shape:SolidMolecular weight:406.44Ref: TM-T6319
1mg39.00€2mg50.00€5mg81.00€10mg131.00€25mg235.00€50mg369.00€100mg537.00€1mL*10mM (DMSO)84.00€Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formula:C44H70O16Purity:98% - 99.5%Color and Shape:SolidMolecular weight:855.02Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48Lupiwighteone
CAS:Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Formula:C20H18O5Purity:98.92%Color and Shape:SolidMolecular weight:338.35L-Leucine
CAS:L-Leucine is an essential amino acid vital for protein synthesis, metabolism, muscle and bone repair, blood sugar control, and wound healing.Formula:C6H13NO2Purity:99.83%Color and Shape:White Solid CrystallineMolecular weight:131.17Palomid 529
CAS:Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Formula:C24H22O6Purity:98.40% - 98.59%Color and Shape:SolidMolecular weight:406.43GNE-477
CAS:GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.Formula:C21H28N8O3S2Purity:98.88% - 99.55%Color and Shape:SolidMolecular weight:504.63Ref: TM-T3692
1mg44.00€2mg57.00€5mg93.00€10mg138.00€25mg286.00€50mg447.00€100mg677.00€1mL*10mM (DMSO)92.00€
