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mTOR

mTOR

mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.

Found 144 products of "mTOR"

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  • ETP-46464

    CAS:
    <p>ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).</p>
    Formula:C30H22N4O2
    Purity:97.76%
    Color and Shape:Solid
    Molecular weight:470.52
  • BGT226 maleate

    CAS:
    <p>BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .</p>
    Formula:C28H25F3N6O2·C4H4O4
    Purity:97.75% - 98.78%
    Color and Shape:Solid
    Molecular weight:650.6
  • NVP-BBD130

    CAS:
    <p>NVP-BBD130 is a stable, ATP-competitive, potent, orally active inhibitor of PI3K and mTOR.</p>
    Formula:C28H21N5O
    Color and Shape:Solid
    Molecular weight:443.5
  • PI3K/mTOR Inhibitor-13

    CAS:
    <p>PI3K/mTOR Inhibitor-13, an oral dual blocker of PI3K and mTOR, may treat sexual diseases, solid tumors, and IPF.</p>
    Formula:C20H13F2N5O3S
    Color and Shape:Solid
    Molecular weight:441.41
  • PI3Ka-IN-5

    CAS:
    <p>PI3Ka-IN-5 is a potent PI3Kα/mTOR inhibitor, with an IC 50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer .</p>
    Formula:C30H35N9O5
    Color and Shape:Solid
    Molecular weight:601.66
  • PKI-179

    CAS:
    <p>PKI-179: Dual PI3K/mTOR inhibitor, orally active, IC50s: 0.42-77 nM, targets E545K and H1047R, antitumor in vivo.</p>
    Formula:C25H28N8O3
    Color and Shape:Solid
    Molecular weight:488.54
  • PKI-179 hydrochloride

    CAS:
    <p>PKI-179: oral PI3K/mTOR inhibitor; IC50: PI3Kα/β/δ/γ (8-74 nM), PI3Kα mutants (11-14 nM), mTOR (0.42 nM); selective; inhibits cancer cell growth.</p>
    Formula:C25H29ClN8O3
    Color and Shape:Solid
    Molecular weight:525
  • PI3K/mTOR Inhibitor-8

    CAS:
    <p>PI3K/mTOR Inhibitor-8: Dual PI3Kα (IC50: 0.46 nM) &amp; mTOR (IC50: 12 nM) inhibitor; blocks G1/S phase &amp; induces apoptosis in HCT-116 cells.</p>
    Formula:C23H22N8O4S
    Color and Shape:Solid
    Molecular weight:506.54
  • eCF-309

    CAS:
    <p>eCF-309 is a potent mTOR inhibitor with IC50 value of 15 nM.</p>
    Formula:C18H21N7O3
    Color and Shape:Solid
    Molecular weight:383.4
  • PI3K/mTOR Inhibitor-4

    CAS:
    <p>Oral PI3K/mTOR Inhibitor-4 targets PI3Kα, γ, δ, mTOR; IC50s: 0.63, 22, 9.2, 13.85 nM. Used in cancer research.</p>
    Formula:C27H22FN3O6S
    Color and Shape:Solid
    Molecular weight:535.54
  • PI3-Kinase α Inhibitor 2

    CAS:
    <p>Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce the second messengers PtdIns-(3,4)-P2 and</p>
    Formula:C16H15N3O2S
    Color and Shape:Solid
    Molecular weight:313.37
  • OXA-01

    CAS:
    <p>OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC 50 values of 29 nM and 7 nM, respectively [1]. OXA-01 demonstrates broad anti-tumor activity.</p>
    Formula:C21H20ClN5O2
    Color and Shape:Solid
    Molecular weight:409.87
  • FT-1518

    CAS:
    <p>FT-1518 is an orally available, selective and potent mTORC1 and mTORC2 inhibitor with anticancer and antitumor activity for cancer research.</p>
    Formula:C20H26N8O
    Purity:98.34% - 98.80%
    Color and Shape:Solid
    Molecular weight:394.47
  • P-2281

    CAS:
    <p>P-2281 is an mTOR inhibitor with anticancer and anti-inflammatory properties.P-2281 inhibits dextran sulfate sodium (DSS)-induced colitis by suppressing T-cell</p>
    Formula:C9H8ClN3O
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:209.63
  • mTOR inhibitor-2

    CAS:
    <p>mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).</p>
    Formula:C23H21N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:411.46
  • PI3K/mTOR Inhibitor-2

    CAS:
    <p>Potent PI3K/mTOR Inhibitor-2 targets PI3Kα/β/δ/γ &amp; mTOR (IC50: 3.4, 34, 16,1, 4.7 nM); exhibits antitumor effects.</p>
    Formula:C20H13ClF2N4O4S
    Purity:96.16%
    Color and Shape:Solid
    Molecular weight:478.86
  • PI3K/mTOR Inhibitor-9

    CAS:
    <p>PI3K/mTOR Inhibitor-9 acts on mTOR (38 nM IC50) and PI3Kα/γ (6.6 nM IC50), PI3Kδ (0.8 nM IC50).</p>
    Formula:C23H27N7O2
    Color and Shape:Solid
    Molecular weight:433.51
  • PP30

    CAS:
    <p>PP30 is an inhibitor of mTORC1 and mTORC2. It is selective within the PI3K family, inhibiting other PI3Ks only at high concentrations.</p>
    Formula:C18H19N7OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:381.45
  • PI3K/mTOR Inhibitor-3

    CAS:
    <p>PI3K/mTOR Inhibitor-3, a potent dual-action anti-cancer imidazoline, targets PI3K and mTOR.</p>
    Formula:C22H23N5O
    Color and Shape:Solid
    Molecular weight:373.45
  • PI-540

    CAS:
    <p>PI-540 is a potent and selective inhibitor of class 1A phosphatidylinositide 3-kinases (PI3K).</p>
    Formula:C22H27N5O2S
    Color and Shape:Solid
    Molecular weight:425.55