mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Found 144 products of "mTOR"
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Zotarolimus
CAS:<p>Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).</p>Formula:C52H79N5O12Purity:95% - 98.01%Color and Shape:SolidMolecular weight:966.21(+)-Usnic acid
CAS:<p>(+)-Usnic acid (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.</p>Formula:C18H16O7Purity:98.22%Color and Shape:SolidMolecular weight:344.32CZ415
CAS:<p>CZ415 is a potent and highly selective mTOR inhibitor.</p>Formula:C22H29N5O4SPurity:97.54% - 98.36%Color and Shape:SolidMolecular weight:459.56VS-5584
CAS:<p>VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.</p>Formula:C17H22N8OPurity:97.82% - 99.54%Color and Shape:SolidMolecular weight:354.41Dihydromyricetin
CAS:<p>Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.</p>Formula:C15H12O8Purity:96.68% - 98.229%Color and Shape:SolidMolecular weight:320.25MHY1485
CAS:<p>MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.</p>Formula:C17H21N7O4Purity:97.74% - >99.99%Color and Shape:SolidMolecular weight:387.39ETP-45658
CAS:<p>ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).</p>Formula:C16H17N5O2Purity:99.14%Color and Shape:SolidMolecular weight:311.34Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Formula:C30H23N5OPurity:97.64% - 99.85%Color and Shape:SolidMolecular weight:469.54PQR620
CAS:<p>PQR620 is a novel potent and selective, brain penetrant inhibitor of mTORC1/2.</p>Formula:C21H25F2N7O2Purity:97.61%Color and Shape:SolidMolecular weight:445.47DMH-25
CAS:<p>DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells.</p>Formula:C15H8Br3NO3Purity:99.26%Color and Shape:SolidMolecular weight:489.94Ridaforolimus
CAS:<p>Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。</p>Formula:C53H84NO14PPurity:90.00% - 98.55%Color and Shape:Off-White SolidMolecular weight:990.21DIM-C-pPhOH
CAS:<p>CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 RNAi in pancreatic cancer.</p>Formula:C23H18N2OPurity:98.61%Color and Shape:SolidMolecular weight:338.4CC-115
CAS:<p>CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).</p>Formula:C16H16N8OPurity:86.79% - 99.01%Color and Shape:SolidMolecular weight:336.35PQR530
CAS:<p>PQR530, a potent dual PI3K/mTORC1/2 inhibitor, blocks PKB and pS6 phosphorylation (IC50: 0.07 μM) and has antitumor properties.</p>Formula:C18H23F2N7O2Purity:99.5%Color and Shape:SolidMolecular weight:407.42PKCβ inhibitor 1
CAS:<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Formula:C24H21N5O2Purity:99.33%Color and Shape:SolidMolecular weight:411.46KU-0060648
CAS:<p>KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ.</p>Formula:C33H34N4O4SPurity:98.75%Color and Shape:SolidMolecular weight:582.71Desmethyl-VS-5584
CAS:<p>Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.</p>Formula:C16H20N8OPurity:>99.99%Color and Shape:SolidMolecular weight:340.38MHY-1685
CAS:<p>MHY-1685 is a mammalian target of rapamycin (mTOR) inhibitor and a senescence inhibitor that can rejuvenate senile hCSCs by modulating autophagy.</p>Formula:C11H8N2O4Purity:99.76%Color and Shape:SolidMolecular weight:232.19DS-7423
CAS:<p>DS-7423: a dual PI3K/mTOR inhibitor; IC50s—PI3Kα: 15.6 nM, mTOR: 34.9 nM, PI3Kβ: 1,143 nM, PI3Kγ: 249 nM, PI3Kδ: 262 nM.</p>Formula:C22H27F3N10O2Purity:99.98%Color and Shape:SolidMolecular weight:520.51Gedatolisib
CAS:<p>Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signaling</p>Formula:C32H41N9O4Purity:98% - 99.36%Color and Shape:SolidMolecular weight:615.73
