Organometallic Ligands
In this category, you will be able to find a large number of organometallic molecules used as ligands in biomolecules. These organometallic ligands can be used in organic chemistry and synthesis in the laboratory. They play a critical role in forming coordination complexes and catalyzing various chemical reactions. At CymitQuimica, we offer a diverse selection of high-quality organometallic ligands to support your research and industrial needs.
Subcategories of "Organometallic Ligands"
- Buchwald Ligands(25 products)
- DPEN(4 products)
- DPHEN(4 products)
- JOSIPHOS(4 products)
- Phosphine(487 products)
- Porphirines(74 products)
Found 2781 products for "Organometallic Ligands".
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DG 172 hydrochloride
CAS:Potent inverse agonist of peroxisome proliferator-activated receptor PPARβ and PPARδ with IC50 value of 27 nM. In mouse myoblasts, DG 172 enhanced recruitment of transcriptional corepressor and down-regulated transcription of PPARβ/δ target gene Angptl4. DG 172 also possess a PPARβ/δ-independent activity on bone marrow cells and promotes dendritic cell differentiation.Formula:C20H20BrN3•HClPurity:Min. 95%Color and Shape:SolidMolecular weight:418.76 g/molTetrabenazine - Bio-X ™
CAS:Controlled ProductTetrabenazine is a drug that has been used for the treatment of Parkinson's disease. It acts by inhibiting dopamine release and reducing the activity of nerve cells in the brain. Tetrabenazine Bio-X is used to treat dyskinesias, that are abnormal and involuntary muscle movements by inhibiting the monoamine transporter (VMAT2). Tetrabenazine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use."Formula:C19H27NO3Purity:Min. 99 Area-%Color and Shape:White PowderMolecular weight:317.42 g/molDovitinib base
CAS:Receptor tyrosine kinase inhibitor; anti-angiogenesis; anti-oncogenesisFormula:C21H21FN6OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:392.43 g/molXaliproden hydrochloride
CAS:An agonist of 5-HT1A serotonin receptors. Neurotrophic and neuroprotective activities have been demonstrated in neurodegenerative models in vivo. This is mediated by increasing the secretion of nerve growth factor (NGF), when tested in astrocytes in vitro. Anti-nociceptive activity was displayed in a model of acute tonic nociceptive and inflammatory pain.
Formula:C24H22F3N•HClPurity:Min. 95%Color and Shape:SolidMolecular weight:417.89 g/molRoflumilast - Bio-X ™
CAS:Roflumilast is a selective phosphodiesterase-4 inhibitor that is used for the treatment of exacerbations in patients with chronic obstructive pulmonary disease (COPD). It is also used to treat plaque psoriasis. This drug has anti-inflammatory and immunomodulatory effects as it aids in increasing levels of cAMP.
Formula:C17H14Cl2F2N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:403.21 g/molPitolisant hydrochloride - Bio-X ™
CAS:Pitolisant is an inverse agonist and antagonist of the histamine (H3) receptor. It acts as an allosteric modulator of the H3 receptor to increase the activity of histamine at the M1 receptor. Pitolisant has been used in the treatment of narcolepsy, schizophrenia and Alzheimer's disease. Its mechanism of action involves binding to the amide group on histamine, which increases its affinity for the H3 receptor and enhances its activity at this site. Pitolisant has been shown to improve cognitive ability and reduce fatigue in patients with Alzheimer's disease. Pitolisant is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C17H26ClNO·HClPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:332.31 g/molES9-17
CAS:Inhibitor of clathrin-mediated endocytosis (CME) and ligand to the clathrin heavy chain (CHC). ES9-17 is an inhibitor of the CHC function with EC50 of 13 μM in plant model Arabidopsis thaliana. ES9-17 is a non-protonophoric CME inhibitor and it does not alter the cytoplasmic pH levels substantially. In a mammalian cell line HeLa, ES9-17 reduced the uptake of transferrin, which is a CME-driven process.
Formula:C10H8BrNO2S2Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:318.21 g/molR-(-)-Arundic acid
CAS:R-(-)-Arundic acid is a chiral compound, which is a derivative of arundic acid specifically designed for enantiomeric purity. It is sourced through synthetic organic chemistry processes, allowing for precise control over its stereochemistry. The mode of action of R-(-)-Arundic acid involves the inhibition of astrocyte activation by modulating the synthesis of certain cytokines and inflammatory mediators. This mechanism provides a neuroprotective effect, making it a valuable tool in the study of neurodegenerative diseases and brain injuries.
Formula:C11H22O2Purity:Min. 98 Area-%Color and Shape:Clear Viscous LiquidMolecular weight:186.29 g/molToceranib phosphate - Bio-X ™
CAS:Controlled ProductToceranib phosphate is a receptor tyrosine kinase inhibitor. Toceranib phosphate has been shown to be effective in the treatment of skin cancer and other types of cancer, including lung cancer and breast cancer. It is approved in the US as a treatment for canine mastocytoma (mast cell tumours).Formula:C22H25FN4O2·H3O4PPurity:Min. 95%Color and Shape:PowderMolecular weight:494.45 g/molVU 6010608
CAS:This compound is a novel negative allosteric modulator of glutamate metabotropic receptor mGlu7. It is highly selective for mGlu7 over other receptors of mGlu class with IC50 = 795 nM. Although VU 6010608 showed favourable brain penetration in rats, it has been proposed as an in vitro tool for electrophysiology studies. The mGlu7 is broadly distributed within the mammalian central nervous system and it plays a key role in neuronal function and synaptic plasticity.
Formula:C18H15F3N4O4Purity:Min. 95%Color and Shape:Solid.Molecular weight:408.33 g/molSorafenib - Bio-X ™
CAS:Sorafenib is a drug that belongs to the class of multikinase inhibitors. It inhibits a number of kinases, including the Mcl-1 protein, which is involved in apoptosis along with blocking picolinic acid (PA), an endogenous metabolite involved in apoptosis signal transduction. Sorafenib also binds to epidermal growth factor receptor (EGFR) on the surface of cancer cells, inhibiting the production of proteins that are required for angiogenesis, thus blocking the formation of new blood vessels. Sorafenib may also inhibit P-glycoprotein (Pgp) activity. Overall, these cytotoxic effects give Sorafenib anti-tumor properties, inhibiting angiogenesis and cellular transformation, which are the two main processes of tumor growth and metastasis. Sorafenib has been shown to be effective against a range of solid tumors such as breast, prostate and lung cancers and is also used for the treatment of metastatic colorectal cancer and renal cell carcinoma. A combination therapy group found that sorafenib was more effective when used with interferon alfa-2b for the treatment of advanced renal cell carcinoma. Sorafenib also has the potential for drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. Sorafenib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C21H16ClF3N4O3Purity:Min. 98%Color and Shape:PowderMolecular weight:464.82 g/molLacidipine - Bio-X ™
CAS:Lacidipine is a lipophilic dihydropyridine calcium channel blocker that is used in the treatment of hypertension. This drug acts as an antihypertensive agent to dilate peripheral arteries and reduces blood pressure. Lacidipine blocks voltage-dependent L-type calcium channels.Formula:C26H33NO6Purity:Min. 95%Color and Shape:PowderMolecular weight:455.54 g/molFingolimod phosphate
CAS:Sphingosine-1-phosphate (S1P) receptor agonist; antineoplastic, immunosppressant
Formula:C19H34NO5PPurity:Min. 95%Color and Shape:PowderMolecular weight:387.45 g/molSEN 12333
CAS:Agonist of alpha7 subtype of nural nicotinic acetylcholine receptorFormula:C20H25N3O2Purity:Min. 95%Color and Shape:SolidMolecular weight:339.43 g/molMitoxantrone hydrochloride
CAS:Inhibits DNA topoisomerase II; antineoplastic; immunomodulatory; antimicrobialFormula:C22H30Cl2N4O6Purity:Min. 97 Area-%Color and Shape:Dark Blue SolidMolecular weight:517.4 g/molFG 7142
CAS:Partial inverse agonist of benzodiazepine sites of the GABAA receptors with anxiogenic properties. FG 7142 is a pharmacological stressor which generates anxiety in humans and in experimental animals such as rhesus monkeys and rodents. FG 7142 also reduces food intake and frequency of feeding in male and female rats.Formula:C13H11N3OPurity:Min. 95%Color and Shape:Yellow PowderMolecular weight:225.25 g/molCyamemazine
CAS:Cyamemazine is a neuroleptic medication, which is a member of the phenothiazine class of compounds. It is synthesized from derivatives of phenothiazine, a group of agents primarily found in pharmaceuticals. The mode of action of cyamemazine involves antagonism at dopamine D2 receptors in the central nervous system. This inhibition of dopamine activity is the principal mechanism through which it exerts its antipsychotic effects. Due to its receptor activity, cyamemazine is used primarily in the management of various psychotic disorders, including schizophrenia and acute psychoses. It also exhibits anxiolytic properties, making it effective in treating anxiety associated with these conditions. By modulating neurotransmitter pathways, cyamemazine helps to alleviate symptoms such as hallucinations, delusions, and agitation, offering therapeutic benefit in complex neuropsychiatric cases. As an atypical antipsychotic, it provides an option for patients who may not respond adequately to other treatments. Although primarily used in a clinical setting, ongoing research continues to investigate potential wider applications and efficacy in treating other mental health issues.Formula:C19H21N3SPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:323.46 g/molLicofelone
CAS:Dual COX/5-LO inhibitor; anti-inflammatory; analgesic
Formula:C23H22ClNO2Purity:Min. 95%Color and Shape:PowderMolecular weight:379.88 g/molPadsevonil
CAS:Padsevonil is an investigational antiseizure medication, which is a synthetic pharmaceutical compound. It is derived from extensive medicinal chemistry research aiming to address complex seizure disorders resistant to conventional treatments. Padsevonil functions by exhibiting a dual mechanism of action. It binds to synaptic vesicle protein 2A (SV2A) with high affinity, similar to levetiracetam but with additional modulation of the benzodiazepine-sensitive gamma-aminobutyric acid-A (GABA-A) receptor. This combined activity potentiates its efficacy in stabilizing neuronal hyperactivity and dampening excitatory neurotransmission, providing a novel angle to tackle refractory seizures.Formula:C14H14ClF5N4O2SPurity:Min. 95%Molecular weight:432.8 g/molPromestriene
CAS:Controlled ProductSynthetic estradiol derivativeFormula:C22H32O2Purity:Min. 95%Color and Shape:PowderMolecular weight:328.49 g/mol
