Deuterated Compounds

Applications Methyl Methacrylate-d5 (CAS# 55935-46-1) is a useful isotopically labeled research compound.

Applications Iodoethane-1,1-d2 is a useful reagent in synthesis of 1,4-benzoquinones.
References Foland, L., et al.: J. Am. Chem. Soc., 111, 975 (1989);

Applications 2,2'-Binaphthyl-d14 (CAS# 210487-05-1) is a useful isotopically labeled research compound.

Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide-d4 is the isotope labelle danalog of N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide. N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).
References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)

Applications 1-Iodo-2,3-dimethoxybenzene-d6 is the isotope labelled analog of 1-Iodo-2,3-dimethoxybenzene. 1-Iodo-2,3-dimethoxybenzene is used in the preparation of fused heterocyclic amido compounds as a potential anti hepatitis C virus agents.
References Aoyama, H., et al.: Bioorg. Med. chem., 19, 2675 (2011);

Applications N,N-Dimethylhexadecylamine-d6 N-Oxide is an isotopic analog of N,N-Dimethylhexadecylamine N-Oxide (7128-91-8).

Stability Hygroscopic
Applications Phenylboronic Acid-d5 is the isotope labelled analog of Phenylboronic Acid (P319590); a compound used in the organic synthesis of various pharmaceutical goods.
References Ainley, A.D., et al.: J. Chem. Soc., 2171 (1930)

Applications Labelled 1-Naphthol (N367990). Used in the manufacturing of dyes, intermediates, synthetic perfumes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Mercaptoethanol-1,1,2,2-d4 (CAS# 284474-53-9) is a useful isotopically labeled research compound.

Applications 3-Mercaptopropionic-2,2,3,3-d4 Acid (CAS# 1141488-67-6) is a useful isotopically labeled research compound. It is used for structural proteomics interactions.
References Petrotchenko, E., et.al., Mol. Cell Proteomics, 8,273-286,(2009);

Stability Hygroscopic
Applications Lauroyl-L-carnitine-d3 Hydrochloride is labelled Lauroyl-L-carnitine (L178680) which is a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Lauroyl-L-carnitine can be diagnostic for a number of ß-oxidation defects.
References Ventura, F., et al.: Clinica Chimica Acta, 281, 1 (1999); Pourfarzam, M., et al.: Clinical Chem,, 40, 2267 (1994); Schaefer, J., et al.: Pediatric Res., 37, 354 (1995)

Applications 3-Pyridylcarbinol-d6 (cas# 1189493-62-6) is a compound useful in organic synthesis.

Applications Flumazenil-D3 is an intermediate in the synthesis of Flumazenil Carboxylic Acid-D3 (F500457), which is an isotope labelled form of Flumazenil Carboxylic Acid (F500455); a derivative of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.
References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)

Applications cis-7,10,13,16-Docosatetraenoic Acid Methyl Ester-d3 is a labelled analog of cis-7,10,13,16-Docosatetraenoic Acid Methyl Ester. cis-7,10,13,16-Docosatetraenoic Acid Methyl Ester is used in oregano essential oil as an inhibitor of higher fatty acid oxidation.
References Terenina, M.B., et al.: Appl. Biochem. Microbiol., 47, 445 (2011)

Applications 9-Fluorenone-D8 is a labelled analogue of 9-Fluorenone (F462780). 9-Fluorenone is a polycyclic aromatic ketone that has photosensitizing properties and also has the ability to undergo electrochemical polymerization. 9-Fluorenone is used in industry as an initiator in visible-light cured resin systems. 9-Fluorenone has potentially toxic effects on humans, as exposure can cause DNA mutations.
References Cihaner, A., et al.: J. Elec. Chem., 568, 151 (2004); Li, Y., et al.: J. Biomed. Mater. Res. Part B-A, 84, 58 (2008); Okamoto, H., et al.: Org. Lett., 13, 2758 (2011)

Applications 1,3,5-Trimethylbenzene-2,4,6-d3 (CAS# 38574-14-0) is a useful isotopically labeled research compound.

Applications 1,12-Dibromododecane-d24 (CAS# 1044544-84-4) is a useful isotopically labeled research compound.

Applications Isotope labelled 4-(4-Bromo-3-fluorophenyl)morpholine, used in the preparation of vascular adhesion protein inhibitors.

Applications 1-Pyrenol-d9 Acetate is a compound useful in organic synthesis.
References Murray, R., et al.: Carcinogen., 20, 147 (1999),

Applications 1,9-Dibromononane-d18 (CAS# 150017-89-3) is a useful isotopically labeled research compound.

Applications Cyclopropyl-1-d1 Methyl-d3 Ketone (CAS# 95249-93-7) is a useful isotopically labeled research compound.

Applications N2-Acetyl Acyclovir Benzoate-d5 is the isotope labelled analog of N2-Acetyl Acyclovir Benzoate (A167975); a derivative of Acyclovir (A192400) which is an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Also an antiviral.
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992); Ashton, D.S., et al.: J. Chromatogr. A, 707, 367 (1995)

Applications Ethyl Glyoxylate-13C4 is an isotope labelled analog of Ethyl Glyoxylate. Ethyl Glyoxylate is used as a reagent in the synthesis of a new class of cinnamyl-triazole compounds which can be used as selective inhibitors of human aromatase (cytochrome P 450 19A1).
References McNulty, J., et al.: Bioorg. Med. Chem. Lett., 24, 4586 (2014)

Applications n-Pentyl 2-Methylpentyl Phthalate-d4, is the labeled analogue of n-Pentyl 2-Methylpentyl Phthalate (P283610), used as plasticizers in the manufacture of products made of polyvinyl chloride.
References Raether, L. O., et al.: Indust. Engineer. Chem. Produc. Res. Develop., 2, 133 (1963);

Applications Glyceryl Tri(hexadecanoate-d31) (CAS# 241157-04-0) is a useful isotopically labeled research compound.

Applications Bis(2-hydroxyethyl)amine-d11 (CAS# 1219804-08-6) is a useful isotopically labeled research compound.

Applications rac-Mono-(4-methyloctanyl)-phthalate-D4 is the isotopically labeled analog of rac-Mono-(4-methyloctanyl)-phthalate. rac-Mono-(4-methyloctanyl)-phthalate, is similar to di-isonoyl phthalate esters (DINPs) which are used as a major plasticizer for poly(vinyl chloride) (PVC). This family of compounds (phthalate) are considered endocrine-disrupting chemicals based on biological studies.
References Hsu, J.F., et al.: Anal. Chem., 83, 8725 (2011)

Applications 2,4-Diamino-6-hydroxypyrimidine-15N3 (cas# 1638736-04-5) is a compound useful in organic synthesis.

Applications 1,5-Diaminonaphthalene (D416415). Aromatic amines likely to have high carcinogenic potency. QSARs of aromatic amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Franke, R., et al.: Carcinogenesis, 22, 1561 (2001), Benigni, R., et al.: Chem. Rev., 105, 1767 (2005), Benigni, R., et al.: Environ. Mol. Mutagen., 50, 152 (2009),

Applications 5alpha-Androstan-3beta-ol-17-one-16,16-d2 (CAS# 79037-35-7) is a useful isotopically labeled research compound.

Applications 2-Chloroethyl (2,6-Dimethylphenyl)-carbamic Acid Ester-d6 is an intermediate used in the synthesis of Dimethachlor Ethane Sulfonic Acid Sodium Salt-d6 (D460284), which is the deuterium labelled form of Dimethachlor Ethane Sulfonic Acid Sodium Salt (D460283), which is a pesticide metabolite and pollutant found in groundwater, surface water, and wastewater.
References Huntscha, S., et al.: J. Chromatogr. A, 1268, 74 (2012); Reemtsma, T., et al.: J. Chromatogr. A, 1271, 95 (2013);

Applications n-Propyl-d7-benzene (CAS# 65087-58-3) is a useful isotopically labeled research compound.

Applications Potassium Tetradecanoate-d27 (CAS# 352438-87-0) is a useful isotopically labeled research compound.

Applications Cefathiamidine-d14 is an isotope labelled antibacterial agent that exhibits a broad spectrum of bactericidal activity against gram-positive bacteria.
References Chen, H.Y., et al.: J. Antimicrob. Chemother., 12, 19 (1983); Philpott-Howard, J., et al.: Scand. J. Infect. Dis. Suppl., 39, 109 (1983); Chen, H.Y., et al.: J. Med. Microbiol., 23, 141 (1987);

Applications N-(Benzoyl)piperazine-2,2,3,3,5,5,6,6-d8 (CAS# 1219805-49-8) is a useful isotopically labeled research compound.

Stability Volatile
Applications N-Pentane-D12 (D, 98%) (cas# 2031-90-5) is a useful research chemical.
E3

Applications Labeled 4-Bromo-1,2-dimethoxybenzene is a metabolite of bromobenzene, with a catechol moiety in the substructure. It also has use as a redox shuttle additive, essentially a component in lithium batteries that consumes excess current during overcharge.
References Billings, R.E. et al.: Drugs. Metab. Disp., 13, 287 (1985); Adachi, M. et al.: J. Electrochem. Soc., 146, 1256 (1999);

Applications Acrylonitrile (D3, 98%) (+0.1% 4-Methoxyphenol) (cas# 53807-26-4) is a useful research chemical.

Applications 1,5-Dibromopentane-1,1,5,5-d4 (CAS# 1219803-90-3) is a useful isotopically labeled research compound.

Applications 3-Bromopropionic-2,2,3,3-d4 Acid is the labeled analog of 3-Bromopropionic acid (B687705). 3-Bromopropionic Acid is used as a reagent in the synthesis of nitrogen containing diselenides which exhibit antioxidant activity. Also used as a reagent in the synthesis of indolin-2-one-based multi-targeted receptor tyrosine kinase inhibitors as potential anticancer agents.
References Nascimento, V., et al.: Eur. J. Med. Chem., 87, 131 (2014); Zhang, L., et al.: Eur. J. Med. Chem., 82, 139 (2014)

Applications Isotope labelled D-Glucitol is a sugar alcohol obtained from the reduction of glucose and is naturally found in various fruits such as apples, pears and peaches. D-Glucitol has been widely used as a sweetener, laxative, various medical applications and in cosmetic products.
References Wang, Z.J., et al.: Anal. BIoanal. Chem., 405, 3899 (2013); Vinarta, S.C., et al.: Carb. Poly., 92, 1107 (2013); Kaumanu, M.L., et al.: Soil. Biol. Biochem., 57, 644 (2013); Hailu, T., et al.: Anal. Biochem., 434, 181 (2013);

Applications 1-Bromohexadecane-d33 (CAS# 284474-41-5) is a useful isotopically labeled research compound.

Applications N2-Methyl Trimethoprim-D3 is a labelled analogue of N2-Methyl Trimethoprim (M331190).

Applications 4-Azidobutyl-d8-amine is the labeled analogue of 4-Azidobutylamine (A822560), which is weakly or non-mutagenic to Salmonella typhimurium.
References Owais, W.M., et. al.: Mutat. Res. Genetic Toxicol. Testing, 118, 229 (1983)

Applications Isotope labelled D-Glucitol is a sugar alcohol obtained from the reduction of glucose and is naturally found in various fruits such as apples, pears and peaches. D-Glucitol has been widely used as a sweetener, laxative, various medical applications and in cosmetic products.
References Wang, Z.J., et al.: Anal. BIoanal. Chem., 405, 3899 (2013); Vinarta, S.C., et al.: Carb. Poly., 92, 1107 (2013); Kaumanu, M.L., et al.: Soil. Biol. Biochem., 57, 644 (2013); Hailu, T., et al.: Anal. Biochem., 434, 181 (2013);

Applications 2-Nitropropane-1,1,1,3,3,3-d6 (CAS# 52809-86-6) is a useful isotopically labeled research compound.

Applications 1-(2-Pyridinyl)benzotriazole-15N3 (cas# 1189465-04-0) is a compound useful in organic synthesis.

Applications Ethyl β-Alanine-2,2,3,3-d4 Ester is an intermediate used in the synthesis of N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine-d4 (C424342), which is an isotope labelled N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine is a metabolite of Tianeptine (T436800), a tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.
References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991), Nair, M. et al.: Analyst, 123, 2267 (1998)

Applications Methyl 3-Bromopropionate-2,2,3,3-d4 (CAS# 1219803-82-3) is a useful isotopically labeled research compound.

Applications Anteisoheneicosanoic acid-d3 is labelled Anteisoheneicosanoic acid which is used in cosmetics as it allows hair fiber to lie flat and parallel with respect to each other while its removal formed coarse tangled bundles, aligned in disorderly manner.
References Tanamachi, H., et al.: J. Cosmetic Sci., 61, 147 (2010); Breakspear, S., et al.: PMSE Preprints, 90, 276 (2004)

Applications A labelled major (toxic) metabolite of Styrene (S687790), catalyzed by epoxide hydrolase.
References Shen, S. et al.: Drug Metab. Disp., 38, 1934 (2010); Carlson, G.P. et al.: J. Toxicol. Env. Health, 73, 1689 (2010)

Applications A labelled derivative of D-Mannosamine (M167000).
References Pukanud, P. et al.: Drug Delivery, 16, 289 (2009);

Applications DL-Homocysteine Thiolactone-3,3,4,4-d4 HCl (CAS# 1219805-31-8) is a useful isotopically labeled research compound.

Applications (±)-Epichlorohydrin-2-d1 (CAS# 70735-27-2) is a useful isotopically labeled research compound.

Applications 7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione-13C6, is a labeled analogue of 7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (D493755), an antioxidant naturally found in aerial parts of Gmelina asiatica Linn (Verbenaceae). It is also found in essential oils of some Stachys species from Mediterranean area. It is an impurity of Irganox 1098 (A697523) used in the food packaging.
References Merlin, N., et al.: Pharmacogn. Res., 1, 152 (2009); Conforti, F., et al.: Food Chem., 116, 898 (2009), Riquet, A. et al.: Food Chem., 199, 59 (2016);

Applications Proven to be an extremely potent and selective a-D-galactosidase inhibitor.
References Paulsen, H., et al.: Chem. Ber., 113, 2601 (1980),

Applications A labelled Voriconazole (V760000) impurity.
References Rieke, R., et al.: Science, 246, 1260 (1989), Dickinson, R., et al.: Bioorg. Med. Chem. Lett., 6, 2031 (1996),

Applications γ-Valerolactone-d3 is the isotope labelled analog of γ-Valerolactone. γ-Valerolactone is a naturally occurring chemical found in fruits and is frequently used as a food additive. It can be converted to liquid alkenes which can be used as transportation fuels.
References Horvath, I.T., et al.: Green Chem., 10, 238 (2008); Bond, J.Q., et al.: Science, 327, 1110 (2010)

Applications trans-Stilbene-alpha,beta-13C2 (CAS# 153610-50-5) is a useful isotopically labeled research compound.

Applications n-Propyl-1,1,3,3,3-d5 Alcohol (CAS# 188894-71-5) is a useful isotopically labeled research compound.

Applications Methyl Benzoate-d8 (CAS# 91929-46-3) is a useful isotopically labeled research compound.

Stability Volatile
Applications 1-Butan-d9-ol is the labeled form of 1-Butanol, which is used for the production of dimethylfuran for liquid fuels.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Roman-Leshkov, Y. et al.: Nature, 447, 982 (2007);