
Deuterated Compounds
Found 4238 products of "Deuterated Compounds"
2-Hydroxy-2-phenyl-d5-1H-indene-1,3(2H)-dione
CAS:Controlled ProductApplications 2-Hydroxy-2-phenyl-d5-1H-indene-1,3(2H)-dione is the labeled analogue of 2-Hydroxy-2-phenyl-1H-indene-1,3(2H)-dione (H949575), an impurity of phenindione (P297250), a proton pump inhibitor and traditional nonsteroidal anti-inflammatory drug used for acute interstitial nephritis and acute kidney injury.
References Haywood, P.A., et. al.: P. Anal. Div. Chem. Soc., 15, 332 (1978); Leonard, C.E., et al.: Pharmacoepidemiol. Drug. Safety., 21, 1155 (2012); Moda, T.L., et al.: Bioorg. Med. Chem. Lett., 22, 2889 (2012); Dhareshwar, S.S., et al.: J. Pharma. Sci., 99, 2711 (2010)Formula:C15H5D5O3Color and Shape:NeatMolecular weight:238.244-(3-Aminobutyl)-phen-2,3,5,6-d4-ol
CAS:Controlled ProductFormula:C10D4H11NOColor and Shape:NeatMolecular weight:169.257Tetrahydro-2-(2-methoxyethoxy)-2H-pyran-d7
CAS:Controlled ProductApplications Tetrahydro-2-(2-methoxyethoxy)-2H-pyran-d7 is an intermediate used in the synthesis of Roxithromycin-d7 (R700852), which is a semisynthetic labeled Erythromycin derivative. Antibacterial.
References Jones, R.N., et al.: Antimicrob. Agents Chemother., 24, 209 (1983), Barry, A.L., et al.: Eur. J. Clin. Microbiol., 5, 536 (1986), Grassi, C., et al.: Chemioterapia, 6, 41 (1987),Formula:C8D7H9O3Color and Shape:NeatMolecular weight:167.254N-Ethylaniline-d5
CAS:Controlled ProductApplications N-Ethylaniline-d5 is labelled N-Ethylaniline (E899362) which is a versatile organic building block used for the synthesis of various pharmaceutical and biologically active compounds. It can be used for the synthesis of benzenesulfonamides as inhibitors of microsomal prostaglandin E2 synthase 1 (mPGES-1) in mice and in humans as potential anti-inflammatory agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hanke, Th., et al.: Biorg. Med. Chem., 21 (24), 7874 (2013)Formula:C8D5H6NColor and Shape:NeatMolecular weight:126.21tert-Butyl-d9-phosphine
CAS:Controlled ProductApplications tert-Butyl-d9-phosphine is the labeled analogue of tert-Butylphosphine (B809330), a reactant in the synthesis of phosphine ligands in metal complexes.
References Wiedner, E.S., et. al.: Organometallics, 29, 5390 (2010)Formula:C4D9H2PColor and Shape:NeatMolecular weight:99.159N-[5-[2-[[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethyl]thio]ethyl]-1,3,4-thiadiazol-2-yl]-benzeneacetamide-d5
CAS:Controlled ProductApplications N-[5-[2-[[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethyl]thio]ethyl]-1,3,4-thiadiazol-2-yl]-benzeneacetamide-d5 is labelled N-[5-[2-[[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethyl]thio]ethyl]-1,3,4-thiadiazol-2-yl]-benzeneacetamide (A630445) which can be used to prepare bis(phenylacetamidothiadiazolyl)ethyl sulfide analogs as glutaminase inhibitors and antitumor agents.
References Shukla, K., et al.: J. Med. Chem., 55, 10551 (2012)Formula:C16D5H13N6OS3Color and Shape:NeatMolecular weight:411.579N-Acetyl Pseudoephedrine-d3
CAS:Controlled ProductFormula:C12D3H14NO2Color and Shape:NeatMolecular weight:210.2872-(4-Nitrophenyl-d4)propane
CAS:Controlled ProductApplications 2-(4-Nitrophenyl-d4)propane (CAS# 1219803-36-7) is a useful isotopically labeled research compound.
Formula:C9H7D4NO2Color and Shape:NeatMolecular weight:169.22Roxatidine-d10 Hemioxalate
CAS:Controlled ProductFormula:C17H16D10N2O3·5C2H2O4Color and Shape:NeatMolecular weight:406.4961,2-Cyclohexanedione-d4
CAS:Controlled ProductApplications 1,2-Cyclohexanedione-d4 is the isotope labelled analog of 1,2-Cyclohexanedione (C988085), a compound used as a substrate to study enzyme cyclohexane-1,2-dione hydrolase as a new tool to degrade alicyclic compounds.
References Fraas, S., et al.: J. Molec. Cataly. B. Enzy., 61, 47 (2009); Steinbach, A., et al.: FEBS. J., 279, 1209 (2012);Formula:C6D4H4O2Color and Shape:NeatMolecular weight:116.151N-Butyrylglycine-2,2-d2
CAS:Controlled ProductApplications N-Butyrylglycine-2,2-d2 (CAS# 1219799-10-6) is a useful isotopically labeled research compound.
Formula:C6H9D2NO3Color and Shape:NeatMolecular weight:147.17Acetic Ethylcarbonic Anhydride-13C2
CAS:Controlled ProductFormula:C2C3H8O4Color and Shape:NeatMolecular weight:134.11-Oxyl-2,2,5,5-tetramethyl-∆3-(methanesulfonyloxymethyl)pyrroline-15N
Controlled ProductStability Moisture Sensitive
Applications 1-Oxyl-2,2,5,5-tetramethyl-∆3-(methanesulfonyloxymethyl)pyrroline is an intermediate in the synthesis of 3-Iodomethyl-(1-oxy-2,2,5,5-tetramethylpyrroline)-15N the isotope labelled analog of 3-Iodomethyl-(1-oxy-2,2,5,5-tetramethylpyrroline) (I709500); a thio-reactive spin label.
References Qin, P.Z., et al.: Biochemistry, 40, 6929 (2001);Formula:C10H1815NO4SColor and Shape:NeatMolecular weight:249.313N,N-Dimethylaniline-2,3,4,5,6-d5
CAS:Controlled ProductApplications N,N-Dimethylaniline-2,3,4,5,6-d5 (CAS# 87385-38-4) is a useful isotopically labeled research compound.
Formula:C8H6D5NColor and Shape:NeatMolecular weight:126.21n-Butyl-d9-benzene
CAS:Controlled ProductApplications n-Butyl-d9-benzene (CAS# 65087-59-4) is a useful isotopically labeled research compound.
Formula:C10H5D9Color and Shape:NeatMolecular weight:143.284-Chlorohippuric Acid-d4
CAS:Controlled ProductApplications 4-Chlorohippuric Acid-d4 is the isotope labelled analog of 4-Chlorohippuric Acid (C367420); a derivative of Hippuric Acid (H356700) and the major metabolite in human urine.
References Köppel, C., et al.: Arzneimittel-Forsch., 36, 1116 (1986); Oelschläger, H., et al.: Die Pharmazie, 53, 620 (1998)Formula:C9H4D4ClNO3Color and Shape:NeatMolecular weight:217.64Chlorobenzene-3,5-d2
CAS:Controlled ProductApplications Chlorobenzene-3,5-d2 (CAS# 59164-10-2) is a useful isotopically labeled research compound.
Formula:C6H3D2ClColor and Shape:NeatMolecular weight:114.57n-Hexadecyl-15,15,16,16,16-d5 Alcohol
CAS:Controlled ProductApplications n-Hexadecyl-15,15,16,16,16-d5 Alcohol (CAS# 1219799-21-9) is a useful isotopically labeled research compound.
Formula:C16H29D5OColor and Shape:NeatMolecular weight:247.48Des[3-[[(1-Carboxymethyl)cyclopropyl]methyl]thio]-2-propenyl Montelukast-d6 Mesylate
CAS:Controlled ProductFormula:C29D6H20ClNO·CH4O3SColor and Shape:NeatMolecular weight:542.119Pantoprazole Sulfide-D7 (Major)
CAS:Controlled ProductApplications A labelled metabolite of Pantoprazole, an antiulcerative, gastric pump inhibitor.
Formula:C16D8H7F2N3O3SColor and Shape:NeatMolecular weight:375.42Bis(6-methylheptyl) Phthalate-3,4,5,6-d4
CAS:Controlled ProductApplications Bis(6-methylheptyl) Phthalate-3,4,5,6-d4 (CAS# 2209087-06-7) is a useful isotopically labeled research compound.
Formula:C24H34D4O4Color and Shape:NeatMolecular weight:394.591-Bromopropane-1,1-d2
CAS:Controlled ProductApplications 1-Bromopropane-1,1-d2 (CAS# 40422-05-7) is a useful isotopically labeled research compound.
Formula:C3H5D2BrColor and Shape:NeatMolecular weight:125.01Fluorene-13C6
CAS:Controlled ProductApplications Fluorene-13C6 is a labelled polycyclic aromatic hydrocarbon.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Di Toro, D., et al.: Environ. Toxicol. Chem., 19, 1971 (2000), Vines, C., et al.: Aquat. Toxicol., 51, 225 (2000), Incardona, J., et al.: Toxicol. Appl. Pharmacol., 196, 191 (2004), Junghans, M., et al.: Aquat. Toxicol., 76, 93 (2006),Formula:C6C7H10Color and Shape:NeatMolecular weight:172.172-Bromoaniline-d4
CAS:Controlled ProductApplications 2-Bromoaniline-d4 is the labeled analogue of 2-Bromoaniline (B679950), a reagent used in the synthesis of substituted 2-carboxanilides as herbicides and antibacterials. Also used in the synthesis of benzisothiazol-3-one derivatives as caspase-3 inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kos, J. et al.: Molecules, 18, 7977 (2013); Liu, D. et al.: Bioorg. Med. Chem., 21, 2960 (2013)Formula:C6D4H2BrNColor and Shape:NeatMolecular weight:176.0471-Iodopropane-2,2,3,3,3-d5
CAS:Controlled ProductApplications 1-Iodopropane-2,2,3,3,3-d5 (CAS# 1095269-04-7) is a useful isotopically labeled research compound.
Formula:C3H2D5IColor and Shape:NeatMolecular weight:175.02Vinyl Acetate-d6
CAS:Controlled ProductApplications Vinyl Acetate-d6 (CAS# 189765-98-8) is a useful isotopically labeled research compound.
Formula:C4D6O2Color and Shape:NeatMolecular weight:92.13N-Boc-piperazine-d4
CAS:Controlled ProductApplications N-Boc-piperazine-d4 is a deuterium labelled analogue of N-Boc-piperazine (B662000).
Formula:C9H14D4N2O2Color and Shape:NeatMolecular weight:190.283-Ethyl-d5-toluene
CAS:Controlled ProductApplications 3-Ethyl-d5-toluene is labelled 3-Ethyltoluene which is a useful synthetic intermediate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormula:C9H7D5Color and Shape:NeatMolecular weight:125.22trans-2,cis-6-Nonadienal-D2
CAS:Controlled ProductApplications trans-2,cis-6-Nonadienal-D2 is a labelled analogue of trans-2,cis-6-Nonadienal (N649365). trans-2,cis-6-Nonadienal is an unsaturated aldehyde that is responsible for the cucumber smell of Synura petersenii, a freshwater colonial flagellate. trans-2,cis-6-Nonadienal is also a common natural and drinking water contaminant.
References Berra, T., et al.: Trans. Am. Fish. Soc., 111, 78 (1982); Kynclova, A., et al.: Nova Hedw. Bei., 136, 283 (2010); Ömür-Özbek, P. & Dietrich, A.: Environ. Sci. Tech., 39, 3957 (2005)Formula:C9D2H12OColor and Shape:NeatMolecular weight:140.2194-Dodecylbenzenesulfonic Acid Potassium Salt-d4
CAS:Controlled ProductFormula:C18D4H25KO3SColor and Shape:NeatMolecular weight:368.609Sodium Acetate-13C2,D3
CAS:Controlled ProductApplications Sodium Acetate-13C2,D3 (cas# 123333-80-2) is a compound useful in organic synthesis.
Formula:C2D3NaO2Color and Shape:NeatMolecular weight:87.04Methyl Linoleate-d3
CAS:Controlled ProductFormula:C19H31D3O2Color and Shape:NeatMolecular weight:297.49Glyceryl Tri(hexadecanoate-2,2-d2)
CAS:Controlled ProductApplications Glyceryl Tri(hexadecanoate-2,2-d2) (CAS# 241157-06-2) is a useful isotopically labeled research compound.
Formula:C51H92D6O6Color and Shape:NeatMolecular weight:813.382-Oxo-3-(phenylmethoxy)propyl bis(phenylmethyl) Ester Phosphoric Acid-13C3
CAS:Controlled ProductFormula:C3C21H25O6PColor and Shape:NeatMolecular weight:443.403Remdesivir-(R)-phosphate-(R)-alanine-D4
Controlled ProductFormula:C27D4H31N6O8PColor and Shape:NeatMolecular weight:606.60Testosterone Laurate-d23
CAS:Controlled ProductApplications Testosterone Laurate-d23 is the isotopic analog of Testosterone Laurate. Testosterone Laurate is a derivative of testosterone(T155000), which is used in analytical studies to determine testosterone and nandrolone esters in race horse plasma for doping control through UPLC-ESI-MS-MS.
References You, Y., et al.: J. Chromato., 1218, 3982 (2011); Guan, F., et al.: Mass Spectrom., 45, 1270 (2010)Formula:C31H27D23O3Color and Shape:NeatMolecular weight:493.87β-L-Aspartylglycine-13C2,15N
CAS:Controlled ProductFormula:C2C4H1015NNO5Color and Shape:NeatMolecular weight:193.1332,6-Dimethyl-d6-nitrobenzene
CAS:Controlled ProductApplications 2,6-Dimethyl-d6-nitrobenzene (CAS# 285138-83-2) is a useful isotopically labeled research compound.
Formula:C8D6H3NO2Color and Shape:ColourlessMolecular weight:157.2(2S,2'S)-Ethambutol-d10 (1,1,1',1',2,2'-d6; ethylene-d4)
CAS:Controlled ProductApplications (2S,2'S)-Ethambutol-d10 (1,1,1',1',2,2'-d6; ethylene-d4) (CAS# 1129526-24-4) is a useful isotopically labeled research compound.
Formula:C10H14D10N2O2Color and Shape:NeatMolecular weight:214.38Ammonium Geranyl Pyrophosphate-D6 Triammonium Salt
CAS:Controlled ProductFormula:C10H23D6N3O7P2Color and Shape:NeatMolecular weight:320.2463-(Methoxy-d3)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2-amine
CAS:Controlled ProductFormula:C11D3H15BN3O3Color and Shape:NeatMolecular weight:254.108Stearidonic Acid Ethyl Ester-d5
CAS:Controlled ProductFormula:C20H27D5O2Color and Shape:NeatMolecular weight:309.5n-Propyl-d7-amine HCl
CAS:Controlled ProductApplications n-Propyl-d7-amine HCl (CAS# 344298-88-0) is a useful isotopically labeled research compound.
Formula:C3H3D7ClNColor and Shape:NeatMolecular weight:102.61rac N-Desmethyl Mephenytoin-D5 (Major)
CAS:Controlled ProductApplications An anticonvulsant, hypnotic. A labelled metabolite of Mephentoin.A representative lot was 85% d5; 15% d4 1% d3 with no detectable d0.
References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980), Knabe, J., et al.: Arch. Phar., 313, 538 (1980),Formula:C112H5H7N2O2Color and Shape:NeatMolecular weight:209.26Bromoethane-2-d1
CAS:Controlled ProductApplications Bromoethane-2-d1 (CAS# 23705-67-1) is a useful isotopically labeled research compound.
Formula:C2H4DBrColor and Shape:NeatMolecular weight:109.97Dimethyl Sulfoxide (13C2, 99%)
CAS:Controlled ProductApplications Dimethyl Sulfoxide (13c2, 99%) (cas# 136321-15-8) is a useful research chemical.
Formula:C2H6OSPurity:99%Color and Shape:NeatMolecular weight:80.111-Bromopropane-d7
CAS:Controlled ProductApplications 1-Bromopropane-d7 is the isotope labelled analog of 1-Bromopropane (B687135); a solvent used for the cleaning of metal surfaces and removal of soldering residues from electronic circuit boards. It is anticipated to be a human carcinogen.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lingyo, Zh., et al.: Toxicology, 304, 76 (2013); Samukawa, M., et al.: Archives Internal Med., 172(16), 1257 (2012)Formula:C3D7BrColor and Shape:NeatMolecular weight:130.03N-[(R)-(4-Nitrophenoxy)phenoxylphosphinyl]-1-ethylpropylester-L-Alanine-D4
Controlled ProductFormula:C20D4H21N2O7PColor and Shape:NeatMolecular weight:440.421-Piperidine-d10-carbonyl Chloride
CAS:Controlled ProductApplications 1-Piperidine-d10-carbonyl Chloride (CAS# 1219803-31-2) is a useful isotopically labeled research compound.
Formula:C6D10ClNOColor and Shape:NeatMolecular weight:157.66Benzilic-d10 Acid (rings-d10)
CAS:Controlled ProductApplications Benzilic-d10 Acid (rings-d10) (CAS# 1219799-12-8) is a useful isotopically labeled research compound.
Formula:C14H2D10O3Color and Shape:NeatMolecular weight:238.30Laquinimod-d5 Sodium Salt
CAS:Controlled ProductFormula:C202H5H14ClN2O2Color and Shape:NeatMolecular weight:359.8611-Isopropyl-d7-piperazine
CAS:Controlled ProductApplications 1-Isopropyl-d7-piperazine (CAS# 2089679-76-3) is a useful isotopically labeled research compound.
Formula:C7H9D7N2Color and Shape:NeatMolecular weight:135.26Benzene-1,2,4-d3
CAS:Controlled ProductApplications Benzene-1,2,4-d3 (CAS# 14941-53-8) is a useful isotopically labeled research compound.
Formula:C6H3D3Color and Shape:NeatMolecular weight:81.13Ethyl 2-Cyanoacetate-13C 15N
CAS:Controlled ProductApplications Ethyl 2-Cyanoacetate-13C 15N, is the labeled analogue of Ethyl Cyanoformate (E907820), which can be used as an intermediate for insecticide, such as Fipronil (F342202).
References Cole, L., et al.: Pestic. Biochem. Physiol., 46, 47 (1993), Cole, L., et al.: Life Sci., 56, 757 (1995), Hosie, A., et al.: Br. J. Pharmacol., 115, 909 (1995),Formula:CC4H715NO2Color and Shape:NeatMolecular weight:115.101Fumaric Acid Monomethyl Ester-13C4
CAS:Controlled ProductApplications Fumaric Acid Monomethyl Ester-13C4, is the labeled analogue of Fumaric Acid Monomethyl Ester (F500390). monomethyl ester is one of the most bioactive anti-psoriatic fumaric acid ester metabolite.
References de Jong, R. et al.: Eur. J. Immunol., 26, 2067 (1996); Litjens, N.H.R. et al.: Br. J. Dermatol., 154, 211 (2006); Schimrigk, S., et al.: Eur. J. Neurol., 13, 604 (2006); Tang, H. et al.: Biochem. Biophys. Res. Comm., 375, 562 (2008);Formula:C4CH6O4Color and Shape:NeatMolecular weight:134.069L-Homocystine-3,3,3’,3’,4,4,4’,4’-d8
CAS:Controlled ProductApplications L-Homocystine-3,3,3’,3’,4,4,4’,4’-d8 is the labeled form of L-Homocysteine (H591360), an increased levels lead to hyperhomocysteinemia; a cardiovascular risk factor in prediction of coronary heart disease as well as being associated with congenital birth defects, pregnancy complications and cancer.
References Geisel, J. et al.: Clin. Chem. Lab. Med., 41, 1513 (2003); Geisel, J. et al.: Clin. Chem. Lab. Med., 41, 1513 (2003);Formula:C8D8H8N2O4S2Color and Shape:White To Off-WhiteMolecular weight:276.4Methyl trans-Cinnamate-d7
CAS:Controlled ProductApplications Methyl trans-Cinnamate-d7 (CAS# 2022152-96-9) is a useful isotopically labeled research compound.
Formula:C10H3D7O2Color and Shape:NeatMolecular weight:169.23N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid-d15
CAS:Controlled ProductApplications N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid-d15 (CAS# 1219794-63-4) is a useful isotopically labeled research compound.
Formula:C6D15NO6SColor and Shape:NeatMolecular weight:244.34(9E,11E,13E,15E)-9,11,13,15-Octadecatetraenoic Acid Methyl-d3 Ester
CAS:Controlled ProductFormula:C19H27D3O2Color and Shape:NeatMolecular weight:293.46Naphthalene-2,3,4,5,6,7,8-d7
CAS:Controlled ProductApplications Naphthalene-2,3,4,5,6,7,8-d7 (CAS# 887-68-3) is a useful isotopically labeled research compound.
Formula:C10HD7Color and Shape:NeatMolecular weight:135.22(S)-2-Acetoxypropanoic Acid-d3
CAS:Controlled ProductFormula:C5D3H5O4Color and Shape:NeatMolecular weight:135.1332-[(Tetrahydro-2H-pyran-2-yl)oxy]ethanol-d4
CAS:Controlled ProductApplications 2-[(Tetrahydro-2H-pyran-2-yl)oxy]ethanol-d4 is an intermediate used in the synthesis of Roxithromycin-d7 (R700852), which is a semisynthetic labelled Erythromycin derivative. Antibacterial.
References Jones, R.N., et al.: Antimicrob. Agents Chemother., 24, 209 (1983), Barry, A.L., et al.: Eur. J. Clin. Microbiol., 5, 536 (1986), Grassi, C., et al.: Chemioterapia, 6, 41 (1987),Formula:C7D4H10O3Color and Shape:NeatMolecular weight:150.209p-Toluidine-d3 (methyl-d3)
CAS:Controlled ProductApplications p-Toluidine-d3 (methyl-d3) (CAS# 23346-25-0) is a useful isotopically labeled research compound.
Formula:C7H6D3NColor and Shape:NeatMolecular weight:110.17Dipotassium Cyclobutane-1,1-dicarboxylate-D4
CAS:Controlled ProductApplications Dipotassium Cyclobutane-1,1-dicarboxylate-D2 is an intermediate in the synthesis of Carboplatin-d4 (C177502), which is an analog of Cisplatin with reduced nephrotoxicity. Antineoplastic.
References Harland, S.J., et al.: Cancer Res., 44, 1693 (1984), Smith, I.E., et al.: Cancer Treat. Rep., 69, 43 (1985), Lygidakis, N.J., et al.: Interferon Cytokine Res., 15, 467 (1995),Formula:C6D4H2K2O4Color and Shape:NeatMolecular weight:224.331(2-Bromoethyl-1,1,2,2-d4)-benzene
CAS:Controlled ProductApplications (2-Bromoethyl-1,1,2,2-d4)-benzene is an intermediate used in the synthesis of Phenelzine-d4 Sulfate (P295902), which is a labeled hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidepressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders.
References MacKenzie, E.M. et al.: Neurochem. Res., 33, 430 (2008);Chiche, F. et al.: Mol. Pharmacol., 75, 1052 (2009); McKenna, K.F, et al.: J. Neural Trans., 41, 115 (1994);Formula:C8H5D4BrColor and Shape:NeatMolecular weight:189.094-Nitrobiphenyl-d9
CAS:Controlled ProductApplications 4-Nitrobiphenyl-d9 (CAS# 350818-59-6) is a useful isotopically labeled research compound.
Formula:C12D9NO2Color and Shape:NeatMolecular weight:208.26D,L-Azetidine-2-carboxylic Acid-d5
CAS:Controlled ProductApplications D,L-Azetidine-2-carboxylic Acid-d5 is a useful synthetic intermediate.
Formula:C4D5H2NO2Color and Shape:NeatMolecular weight:106.1351-(4-Nitrophenyl)cyclopentanecarbonitrile-d8
CAS:Controlled ProductApplications 1-(4-Nitrophenyl)cyclopentanecarbonitrile-d8 is an intermediate used in the synthesis of Apatinib-d8 Hydrochloride (A726152), which is labelled Apatinib (A726150). Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.
References Mi, Y. et al.: Cancer Res., 70, 7981 (2010); Tong, X.Z. et al.: Biochem. Pharmacol., 83, 586 (2012); Ding, J, et al.: J. Chrom B Anal. Technol. Biomed. Life Sci., 895, 108 (2012);Formula:C12D8H4N2O2Color and Shape:NeatMolecular weight:224.2854-Chlorobenzonitrile-d4
CAS:Controlled ProductApplications 4-Chlorobenzonitrile-d4 (CAS# 1219794-82-7) is a useful isotopically labeled research compound.
Formula:C7D4ClNColor and Shape:NeatMolecular weight:141.598-Bromo-3,7-dihydro-3-methyl-7-(1-methylethyl)-1H-purine-2,6-dione-d7
CAS:Controlled ProductApplications 8-Bromo-3,7-dihydro-3-methyl-7-(1-methylethyl)-1H-purine-2,6-dione-d7, is the labeled analogue of (B683490), which is a substituted derivative of Xanthine (X499950).
References Mueller, C. et. al: Handbook Exp. Pharmacol. 200,151(2011)Formula:C9D7H4BrN4O2Color and Shape:NeatMolecular weight:294.156rac trans-1,2-Dihydroxy-1,2-dihydronaphthalene-d6
CAS:Controlled ProductApplications Labelled analogue trans-1,2-Dihydroxy-1,2-dihydronaphthalene, a metabolite of Naphthalene.
References Sun, Y. et al.: Arch. Toxicol., 80, 280 (2006); Cho, T. et al.: Drug Metab. Drug Interact., 22, 235 (2007); Iwamoto, N. et al.: J. Biol. Chem., 282, 33396 (2007);Formula:C10H4D6O2Color and Shape:NeatMolecular weight:168.22trans-1,2-Dimethylcyclopentane-d4
CAS:Controlled ProductFormula:C7D4H10Color and Shape:NeatMolecular weight:102.211Sitagliptin Triazecine Analog-D4
Controlled ProductFormula:C16D4H9F6N5O2Color and Shape:NeatMolecular weight:425.322Hexadecyltrimethylammonium Bromide-d9
CAS:Controlled ProductApplications Isotope labelled Hexadecyltrimethylammonium Bromide (CTAB) (H293860), is a cationic surfactant used as a template in the synthesis of Mesoporous γ-Fe2O3.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yu, H.-h., et al.: Gongneng Cailiao, 42, 2005 (2011),Formula:C192H9H33N·BrColor and Shape:NeatMolecular weight:373.50Indene-d3
CAS:Controlled ProductApplications Isotope labelled Indene is an organic building block that has been used in the synthesis of isatins as selective inhibitors of carboxylesterases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hyatt, J.L., et. al.: J. Med. Chem., 50, 1876 (2007)Formula:C9H5D3Color and Shape:NeatMolecular weight:119.185-Bromohexahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid-15N2
CAS:Controlled ProductApplications 5-Bromohexahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid-15N2 is an intermediate used in the synthesis of Orotic Acid-15N2 Monohydrate (O691504), which is a labeled analogue of Orotic Acid Monohydrate (O691500) that is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment. Also, it is the labeled form of 5-Bromohexahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid (B699363), an intermediate in synthesizing Orotic Acid Monohydrate (O691500), which is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.
Formula:C5H5Br15N2O4Color and Shape:NeatMolecular weight:238.9955-Amino-1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methyl-4-oxo-3-quinolinecarboxylic Acid-d4
CAS:Controlled ProductFormula:C14D4H8F2N2O3Color and Shape:NeatMolecular weight:298.278(S)-N-Desmethyl Citalopram Hydrochloride-d3
CAS:Controlled ProductFormula:C19D3H16FN2O·HClColor and Shape:NeatMolecular weight:349.845Iodobenzene-13C6
CAS:Controlled ProductApplications Used for preparation of uniformly Labelled 13C polychlorobiphenyl (PCB) standard.
References McCurry, J.D., et al.: Anal. Chem., 58, 2785 (1986),Formula:C6H5IColor and Shape:NeatMolecular weight:209.964Diallyl Disulphide-d10
CAS:Controlled ProductApplications Diallyl Disulphide-d10 is labelled Diallyl Disulphide (D416035) which has a range of uses varying from a Cytocrome P450 inhibitor to vasorelaxant and hypotensive. Being in the class of organosulfur compounds, it carries chemopreventive characteristics.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Reddy, B.S. et al.: Cancer Res., 53, 3293 (1993); Bautista, D.M. et al.: Proc. Nat. Acad. Sci. U.S.A., 102, 12248 (2005); Bourrie, M. et al.: J. Pharmacol. Exp. Ther., 277, 321 (1996);Formula:C6D10S2Color and Shape:NeatMolecular weight:156.3352,4,5-Triamino-6-hydroxypyrimidine-13C2 Sulfate Salt
CAS:Controlled ProductApplications 2,4,5-Triamino-6-hydroxypyrimidine-13C2 Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity.
References Prochazkova, E. et al.: Free Radical Res., 46, 61 (2011); Lin, S. et al.: J. Med. Chem., 22, 741 (1979)Formula:C2C2H7N5O·H2SO4Color and Shape:NeatMolecular weight:241.1952-Propylisonicotinonitrile-D7
CAS:Controlled ProductApplications 2-Propylisonicotinonitrile-D7 is an intermediate in the synthesis of the labelled Protionamide (P838865). An anti-tuberculosis agent. It has also been used to treat Leprosy. Antibacterial (tuberculostatic).
References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), van Ingen, J., et al.: Int. J. Antimicrob. Agents, 35, 169 (2010), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010),Formula:C9D7H3N2Color and Shape:NeatMolecular weight:153.2322,4,5-Trichloroaniline-d4
CAS:Controlled ProductApplications 2,4,5-Trichloroaniline-d4 (CAS# 1219804-61-1) is a useful isotopically labeled research compound.
Formula:C6D4Cl3NColor and Shape:NeatMolecular weight:200.482,3’-Anhydrothymidine-d3
CAS:Controlled ProductApplications: An intermediate in the preparation of labelled thymidine derivatives
References el Kouni, M., et al.: Biochem. Pharmacol., 51, 1687 (1996),Formula:C10D3H9N2O4Color and Shape:NeatMolecular weight:227.23220-Carboxy Arachidonic Acid-d8
CAS:Controlled ProductFormula:C20D8H22O4Color and Shape:NeatMolecular weight:342.499Glyceryl Tri(hexadecanoate-16,16,16-d3)
CAS:Controlled ProductApplications Glyceryl Tri(hexadecanoate-16,16,16-d3) (CAS# 285979-78-4) is a useful isotopically labeled research compound.
Formula:C51H89D9O6Color and Shape:NeatMolecular weight:816.39n-Pentyl-5,5,5-d3 Alcohol
CAS:Controlled ProductApplications n-Pentyl-5,5,5-d3 Alcohol (CAS# 64118-19-0) is a useful isotopically labeled research compound.
Formula:C5H9D3OColor and Shape:NeatMolecular weight:91.171-Butane-d9-sulfonyl Chloride
CAS:Controlled ProductApplications 1-Butane-d9-sulfonyl Chloride (CAS# 1219794-70-3) is a useful isotopically labeled research compound.
Formula:C4D9ClO2SColor and Shape:NeatMolecular weight:165.682-Chlorophenol - 13C6
CAS:Controlled ProductApplications 2-Chlorophenol is an intermediate used in the synthesis of Diclofenamide-13C6 (D436532), which is a labeled Diclofenamide, a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP).
References Brzozowski, Z. et al.: Eur. J. Med. Chem., 46, 3656 (2010); Tawil, R. et al.: Ann. Neurol., 47, 46 (2000); Casey, J. et al.: J. Med. Chem., 47, 2337 (2004);Formula:C6H5ClOColor and Shape:NeatMolecular weight:134.5121-Bromononane-d19
CAS:Controlled ProductApplications 1-Bromononane-d19 (CAS# 1219805-90-9) is a useful isotopically labeled research compound.
Formula:C9D19BrColor and Shape:NeatMolecular weight:226.27Dibenz[a,h]acridine-d6 (Major)
CAS:Controlled ProductApplications Labelled Dibenz[a,h]acridine (D416900). A urinary metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons in hot mix asphalt paving workers. A heterocyclic aromatic compound with potent mutagenic and carcinogenic properties.One of the azaarenes found in grilled meat.
References Smith, C.J., et al.: Food Chem. Toxicol., 38, 637 (2000), Koehler, D.A., et al.:; J. Ind. Ecol., 9, 143 (2005), Arnot, J.A., et al.: Environ. Toxicol. Chem., 27, 341 (2008),Formula:C21H7D6NColor and Shape:NeatMolecular weight:285.37Suberic Acid Bis(3-sulfo-N-hydroxysuccinimide ester)-d4 Disodium Salt
CAS:Controlled ProductFormula:C16D4H14N2Na2O14S2Color and Shape:NeatMolecular weight:576.453Diethyl 3,7-Bis(formyloxy)-25-methyl-cholestane-26,27-dioic Acid Ester-d3
CAS:Controlled ProductApplications Diethyl 3,7-Bis(formyloxy)-25-methyl-cholestane-26,27-dioic Acid Ester-d3 is an intermediate used in the synthesis of 3α,7α-Dihydroxycoprostanic Acid-d3 (D452517), which is a labelled analogue of 3α,7α-Dihydroxycoprostanic Acid (D452515), a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3α,7α-Dihydroxycoprostanic Acid.
References Hanson, R. F., et al.: Science (Washington, DC, U. S.), 203, 1107 (1979)Formula:C34D3H51O8Color and Shape:NeatMolecular weight:593.806
