Deuterated Compounds

<p>Applications L-Methionine-d3-N-FMOC (S-methyl-d3) (CAS# 502692-58-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-(N-Morpholino)propanesulfonic Acid-d15 (CAS# 1219799-30-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Heptanoic-2,2,3,3-d4 Acid (CAS# 1219803-28-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Diethylamine-13C4 Hydrochloride is the labelled salt of Diethylamine (D443485).<br></p>

<p>Applications 1,1,1,2-Tetrachloroethane-d2 (CAS# 117164-18-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromooctane-d17 (CAS# 126840-36-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Acetamidine-d3 Hydrochloride is a useful compound in the synthesis of 3-​Chloro-​3-​methyl-​d3-​diazirine (CAS# 35496-73-2).<br>References Liu, M. T. H., et al.: J. Org. Chem., 45, 4515 (1980)<br></p>

<p>Applications Phthalic Anhydride-13C is used as a reactant in the synthesis of Nefopam-13C hydrochloride.Phthalic Anhydride-13C is an isotope labelled version of Phthalic Anhydride (P384485).<br>References Bunker, James E., et al.: J. of Lab. Compds and Radiopharma., 17(5), 691-8 (1980)<br></p>

<p>Applications Diethylamine-d11 (CAS# 1173019-51-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isotope labelled 1,2-Pentanediol is used in synthesizing quinoxalines from biomass-derived glycols. Also used in the synthesis of propiconazole (P770100) a fungicide as well as other antifungals.<br>References Climent, M. et al.: J. Catal., 292, 118 (2012); Zhou, Y. et al.: Carbo. Res., 344, 1289 (2009);<br></p>

<p>Applications n-Nonanoic-9,9,9-d3 acid is labelled n-Nonanoic Acid (N649385) which is commonly used in conjunction with glyphosate, a non-selective herbicide, for a quick burn-down effect in the control of weeds in turfgrass. It is also used in the preparation of plasticizers and lacquers.<br>References Pline, W., et al.: Weed Technol., 14, 667 (2000); Frade, J., et al.: Anal. Bioanal. Chem., 395, 2167 (2009)<br></p>

<p>Applications n-Hexyl Sec-Hexyl Phthalate-d4, is the labeled analogue of n-Hexyl Sec-Hexyl Phthalate (H297200), a phthalic acid ester (PAEs), widely used in many consumable products with potential carcinogenic properties.<br>References Wang, Zh., et al.: Guocheng Gongcheng Xuebao, 5 (6), 670 (2005);<br></p>

<p>Applications Ethyl 2,3-Dicyanopropionate-13C2 15N2, is the labeled analogue of Ethyl 2,3-Dicyanopropionate (E915950), which is an intermediate for insecticide.<br>References Cole, L., et al.: Pestic. Biochem. Physiol., 46, 47 (1993), Cole, L., et al.: Life Sci., 56, 757 (1995), Hosie, A., et al.: Br. J. Pharmacol., 115, 909 (1995),<br></p>

<p>Applications N-(Carboxymethyl)-N,N,N-trimethyl-d9-ammonium Chloride (CAS# 285979-85-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications n-Tricosane-d48 (CAS# 203784-75-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Sodium Hexadecanoate-d31 (CAS# 467235-83-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Bromo-2-(ethyl-d3)pyridine is an intermediate in the synthesis of Ethionamide-d3 (E890422), a labelled antibacterial (tuberculostatic) agent.<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>

<p>Applications Ethyl-alpha,alpha-d2-benzene-d5 (CAS# 84272-90-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isotope labelled 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol, the novel raw material for deodorants application and is widely used as a cosmetic emollient. 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol reliably inhibits the odor-causing bacteria, yeast and fungi on the skin.<br>References Nagao, S.: Frag. J., 34, 39 (2006); Lawan, K. et al.: J. Health Sci., 23, 1 (2009); Leschke, M.: SOFW J., 136, 10 (2010);<br></p>

<p>Applications Herbicide.<br>References Oehler, D.D., et al.: J. Agric. Food Chem., 28, 685 (1980),<br></p>

<p>Applications Sodium Hexanoate-d11 (CAS# 340257-58-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2,3-Dibromo-1-propan-1,1,2,3,3-d5-ol is a labelled analogue of 2,3-Dibromo-1-propanol (D425522), which is a metabolite of the flame retardant tris(2,3-dibromopropyl) phosphate (T775560), previously shown to be a mutagen and carcinogen in experimental animals. It is also an intermediate in synthesizing Bis(2,3-dibromopropyl) Phosphate-d10 (B426237), which an isotope labelled analog of Bis(2,3-dibromopropyl) Phosphate. Bis(2,3-dibromopropyl) Phosphate is a derivative of Tris(2,3-dibromopropyl) Phosphate, a widely used flame retardant in plastic and textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pandith, A.H., et al.: Org. Chem. Int., 17, (2010); Dixon, D., et al.: Toxicol. Pathol., 36,428 (2008);Eustis, S.L., et al.: Toxiciol. Sci., 26, 41 (1994); Elliott, W.C., et al.: Life. Sci., 7, 1107 (1983);<br></p>

<p>Applications 4-Fluorobenzyl-d6 Alcohol (CAS# 1071809-48-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2,3-Dichlorobenzoic-d3 Acid (CAS# 1126107-18-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Carcinogenic compound commonly found in hair dyes and henna ink, also a commonly used synthetic intermediate<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mulyono; T., et al.: J. Biosci. Bioeng., 103, 147 (2007), Mosley-Foreman, C., et al.: Food Chem. Toxicol., 46, 3780 (2008), Patel, A.K., et al.: J. Agric. Food Chem., 56, 9236 (2008), Akyuz, M., et al.: J. Pharm. Biomed. Anal., 47, 68 (2008),<br></p>

<p>Applications 4-Fluorobenzyl-2,3,5,6-d4-amine (CAS# 1219798-96-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Phenyl-d5-acetylene (CAS# 25837-46-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications n-Butylamine-ND2 DCl (CAS# 156235-87-9) is a useful isotopically labeled research compound.<br>Chemical Name: n-Butylamine-ND2 DCl (CAS# 156235-87-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Cyclopropane-d5-carboxylic Acid (CAS# 1219804-09-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Benzyl-2,3,4,5,6-d5 Acetate (CAS# 1398065-57-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-(2-Ethoxy-2-oxoethyl)pyridin-1-ium-d5 Chloride is an intermediate used in the synthesis of Girard’s Reagent P-d5 (G388502), which is a labeled girard’s reagent used in the identification and quantification of protein carbonylation as well as in the modification of nucleosides and nucleotides. Used in the preparation of potent photoactive agents.<br>References Mirzaei, H. et al.: J. Chrom. A, 1134, 122 (2007); Kanofsky, J.R. et al.: Photochem. Photobiol., 73, 349 (2001);<br></p>

<p>Applications Benzyl-alpha,alpha-d2 Alcohol (CAS# 21175-64-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Acetyl-L-alanine-3,3,3-d3 (CAS# 1485548-36-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Heptyl 5-Methyl-2-hexyl Phthalate-d4, is the labeled analogue of Heptyl 5-Methyl-2-hexyl Phthalate, a phthalate ester used as plasticizers and additives.<br>References Peterson, J.C., et al.: Int. J. Envrion. Anal. Chem., 18, 237 (1984);<br></p>

<p>Applications Ethyl Cyanoacetate-13C3 is an intermediate used in the synthesis of 3-Hydroxypropionic Acid-13C3 Sodium Salt (H952481), which is an isotope labelled analogue of 3-Hydroxypropionic Acid Sodium Salt (H952480), which is beta hydroxy acid derived from plants and crops such as corn. 3-Hydroxypropionic Acid is used in the preparation of acrylates and biodegradable polymer polyester.<br>References Wang, Y. et al.: Biomacromol., 3, 828 (2002); Jiang, X. et al.: Appl. Microbiol. Biotech., 82, 995 (2009);<br></p>

<p>Applications 2-Phenylpropane-1,1,1,3,3,3-d6 (CAS# 20201-29-0) is a useful isotopically labeled research compound.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-Propyl-d5-amine is labelled 1-Propylamine (P833700) which is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. It is also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Cresyl Diphenyl Phosphate-d7 Isomer 3 is the deuterated form of Cresyl Diphenyl Phosphate (C783015), which is a phosphorus flame retardant additive.<br>References van der Veen., et al.: Chemosphere, 88, 1119 (2012);<br></p>

<p>Stability Volatile<br>Applications rac 1,2-Diaminopropane-d3 is labelled rac 1,2-Diaminopropane which was used as model precursor in the electron induced deposition of amorphous carbon nitride films. It was also used to synthesize cage peroxide, 1,6-diaza-3,4,8,9-tetraoxa-11-methylbicyclo[4.4.2]dodecane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wnuk, J., et al.: J. Phys. Chem., 113, 12345 (2009); Edward, J., et al.: Can. J. Chem., 77, 1057 (1999)<br></p>

<p>Applications 6-Chloro1,4-dihydro-1-methyl-4-phenyl-4-quinazolinol-13CD3 is the isotope labelled analog of 6-Chloro1,4-dihydro-1-methyl-4-phenyl-4-quinazolinol. 6-Chloro1,4-dihydro-1-methyl-4-phenyl-4-quinazolinol is used in hydroxyglycine reactions in determining a new synthetic route for phenylquinazoline derivatives.<br>References Hoefnagel, A.J., et al.: Tetrahedron, 49, 6899 (1993)<br></p>

<p>Applications Phthalic Acid Bis(3,7-dimethyloctyl) Ester-d4 is the isotope labelled analog of Phthalic Acid Bis(3,7-dimethyloctyl) Ester (P384535); a diester derivative of Phthalic Acid (P384480) which can be used as a plasticizer for PVC-type compositions.<br>References Takeuchi, H., et al. Jpn. Kokai Tokkyo Koho. JP 2001002829 A 20010109. Jan 9, 2001<br></p>

<p>Applications Choline-d13 Bromide (cas# 203645-64-1) is a useful research chemical.<br></p>

<p>Applications 2-(Ethyl-d3) Isonicotinamide is an intermediate in the synthesis of Ethionamide-d3 (E890422), a labelled antibacterial (tuberculostatic) agent.<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>

<p>Applications Labelled Isopentenyl Pyrophosphate. Used for the preparation of antitumor agents phosphohalohydrins.<br>References Dhe-Paganon, S., et al.: Biochem., 33, 13355 (1994), Tanaka, Y., et al.: Nature, 375 155 (1995), Wesch, D., et al.: Eur. J. Immunol., 27, 952 (1997),<br></p>

<p>Applications Hexadecanoic-15,15,16,16,16-d5 Acid (CAS# 285979-77-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Labelled 2,4-Diaminobutyric Acid. 2,4-Diaminobutyric Acid is a pharmacological tool and potential chiral building block. 2,4-Diaminobutyric Acid is also used as an internal standard for amino acid analysis. 2,4-Diaminobutyric Acid is also found to inhibit GABA transaminase, thus producing an elevation of GABA level, and to have an antitumor activity in vitro and in vivo against mouse fibrosarcoma cells.<br>References Riordan, J.F. et al.: Methods Enzymol., 47, 31 (1977); Beart, P.M. et al.: Neurscience Lett., 5, 193 (1977); Ronquist, G. et al.: J. Cancer Res. Clin. Oncol., 96, 259 (1980); Solladie-Cavallo, A. et al.: Tetrahedron Lett., 30, 6011 (1989);<br></p>

<p>Applications Vinylene-D2 Carbonate is deuterium labelled analogue of Vinylene Carbonate (V375010), which is used as an additive for electrolyte solutions for Lithium-ion and Sodium-ion batteries.<br>References Aurbach, D., et al.: Electrochim. Acta, 47, 1423 (2002); Hu, Y., et al.: Angew. Chem. Int. Ed., 47, 1645 (2008); Komaba, S., et al.: Adv. Funct. Mater., 21, 3859 (2011);<br></p>

<p>Applications L-2-Aminobutyric-3,3-d2 Acid (CAS# 352431-37-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3,5-Benzene-2,4,6-d3-tricarboxylic Acid (CAS# 62790-27-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Deoxycholic Acid-24-13C (CAS# 52886-37-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-n-Octyl-d17-anisole (CAS# 1219794-56-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Cyclopropylmethanol-d3, is a labeled analogue of Cyclopropylmethanol (C988605), which is used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones<br>References Hu, E. et al.: Bioorg. Med. Chem. Lett., 22, 6938 (2012);<br></p>

<p>Applications Bis(m-cresyl) o-Cresyl Phosphate-d7 is labelled Bis(m-cresyl) o-Cresyl Phosphate (B419220), an isomer of Tricresyl phosphate (TCP) which is used as an anti-wear additive in aircraft turbine engine oil.<br>References De Nola, G., et al.: J. Chrmoat. A, 1200, 211 (2008)<br></p>

<p>Applications 2-Nitrobiphenyl-d9 (CAS# 38537-53-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isotope labelled Glycerol (G598400) is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.<br>References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976),<br></p>

<p>Applications 4-Hydroxypiperidine-3,3,4,5,5-d5 (CAS# 1219799-35-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Fluoro-1,3-dioxolan-2-one-d3 is the labeled version of 4-Fluoro-1,3-dioxolan-2-one (F591523)<br></p>

<p>Applications (2,4-Dichlorophenoxy-d3)acetic-d2 Acid (CAS# 352438-69-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Methylform-d1-amide (CAS# 26103-38-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications Tetradecanoic-14,14,14-d3 Acid (CAS# 62217-71-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Malathion (Diethyl-d10) is used as one of the substances for the clean-up step in post-harvest pesticide residue analysis.<br>References Ucles, A., et al.: Talanta, 144, 51 (2015)<br></p>

<p>Applications Reagent used in the addition of labelled cyclopropane.<br></p>

<p>Applications Sodium 2-Methylpropionate-1-13C (CAS# 71105-51-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Tetra-n-propyl-d28-ammonium Bromide (CAS# 284474-84-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Ethylene Glycol Distearate-d4 is a deuterated version of Ethylene Glycol Distearate (E917572), a component of face wash and shampoo.<br>References Kang, Daiping, et al.: Guangdong Huagong, 42(6), 60-62 (2015);Zhang, Kai, et al.: Guangdong Huagong, 42(19), 69-70 (2015);Yu, He, et al.: Guangdong Huagong, 40(1), 27, 45 (2013)<br></p>

<p>Applications n-Hexadecyltrimethylammonium-d42 Chloride (CAS# 2095863-88-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Iodo-2,3-dimethoxybenzene-d6 is the isotope labelled analog of 1-Iodo-2,3-dimethoxybenzene. 1-Iodo-2,3-dimethoxybenzene is used in the preparation of fused heterocyclic amido compounds as a potential anti hepatitis C virus agents.<br>References Aoyama, H., et al.: Bioorg. Med. chem., 19, 2675 (2011);<br></p>

<p>Applications Cardiogenol C-d4, Hydrochloride is an isotope labelled analog of Cardiogenol C, Hydrochloride. Cardiogenol C, Hydrochloride is a potent, cell permeable inducer of embryonic stem cell differentiation in cardiomyocytes displaying an Ec50 of 100nm.<br>References Wu, X., et al.: J. Am. Chem. Soc., 126, 1590 (2004)<br></p>