Building Blocks

Importazole is a protein that inhibits the polymerase chain reaction (PCR) by binding to the DNA strand. It has been shown to inhibit cancer cell proliferation and induce apoptosis in HL-60 cells. Importazole also prevents the binding of taxane drugs to nuclear receptors, which may be beneficial for chemotherapy treatment. Importazole binds to DNA and blocks transcriptional regulation, which leads to neuronal death in rats. This protein has been shown to bind to both DNA and receptor activity, and also has an effect on cell nuclei.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Furo[3,2-b]pyridine-2-carboxylic acid is a borohydride diester with the molecular formula CHB(OCH)CHB(OH)COOH. It is created by the decarboxylation of furopyridine (a compound of the class of furopyridines), followed by hydrolysis and cyclization. It can be synthesized by reacting ethyl bromoacetate with phosphoric acid and then hydrolyzed to yield a hydroxy derivative. Furo[3,2-b]pyridine-2-carboxylic acid is used in organic chemistry as an intermediate for other compounds, such as pharmaceuticals and pesticides.

2-Benzyl-2-azabicyclo[2.2.1]hept-5-ene is a reactive molecule that belongs to the class of carbocyclic nucleosides. It reacts with a variety of functional groups, including amide groups and iminium groups, which makes it a useful monomer for peptidomimetic synthesis, as well as copolymerization with other monomers. This compound yields high molecular weight polymers with amide and iminium functionalities in good yield, making it an attractive polymer candidate for drug delivery and biomedical applications.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2H-Benzo[b][1,4]oxathiepin-3(4H)-one is a hydrazine that can be used as an intermediate in chemical synthesis. It has the chemical properties of a carbonyl group, which includes an acyclic structure and α-amino acid substituents. 2H-Benzo[b][1,4]oxathiepin-3(4H)-one is an interaction compound that has been shown to have a cyclic structure with carboxylic acid substituents. The chemical properties of 2H-benzo[b][1,4]oxathiepin-3(4H)-one are similar to hydroxylamine.END>>

Versatile small molecule scaffold

1-Cyclohexylcyclopropan-1-ol is an organic compound with the molecular formula C8H14O. It is a primary alcohol that can be obtained by the oxidation of cyclohexanol or cyclopentanol, or by the reduction of cyclopentanone. 1-Cyclohexylcyclopropan-1-ol can also be obtained from natural products, such as macrocyclic diterpenoids and tetraisopropoxide. 1CPC has been identified as a potential precursor to trifluoroacetylated cyclic peptides, which are more stable than linear peptides and have shown pluripotent properties in vitro. 1CPC is a good solvent for amines and it has been used in the synthesis of histone deacetylase inhibitors.

Versatile small molecule scaffold

3-Imidazol-1-yl-phenylamine is an organic compound that contains both aromatic and heterocyclic moieties. 3-Imidazol-1-yl-phenylamine has high thermal stability and selectivity, as well as affinity for ionic membranes. It is used in the chemical industry to transport cations such as K+, Na+, Li+, NH4+ and Ca2+. The imidazolium functional group in 3-imidazol-1-yl phenylamine contributes to its membrane affinity and ion transport properties. This compound also has a low toxicity and is not flammable or corrosive at room temperature.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold