Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Cabozantinib is a small molecule that is the first to target VEGFR-2, which is a receptor tyrosine kinase involved in the development of fibrosis. Cabozantinib inhibits the activity of VEGFR-2 by binding to its ATP-binding site and blocking the phosphorylation of downstream signaling pathways. Cabozantinib has been shown to have antifibrotic properties in both preclinical and clinical models. The drug candidate has been shown to reduce kidney fibrosis in animal models. The standard dose for cabozantinib was found to be 5 mg/kg, with a maximum tolerated dose of 20 mg/kg. In vitro studies have indicated that cabozantinib binds with high affinity to the ATP-binding pocket of VEGFR-2, exhibiting competitive inhibition against other kinases such as PDGFR-beta and cKit, as well as diaryliodonium (a specific inhibitor). Caboz</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chloropyrimidine-2-carbonitrile is an industrial chemical that belongs to the class of heterocycles. It is commonly used in the synthesis of amines, phenoxy compounds, and halides. This compound is widely used in research laboratories as a building block for the synthesis of various organic compounds. 4-Chloropyrimidine-2-carbonitrile is available in enantiopure form, making it suitable for chiral chemistry applications. It contains cyano and ethoxycarbonyl functional groups, which make it versatile for further derivatization. This compound exhibits solid catalyst properties and can be used as a methyl ether or amide precursor. Its emission properties make it useful in fluorescence-based assays and imaging techniques.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Aminopyrrolidin-2-one hcl is an antibiotic that is used to treat tuberculosis. It inhibits the enzyme transacylase, which catalyses the conversion of L-lysine into L-pipecolic acid in bacteria. This antibiotic has been shown to be effective against Mycobacterium tuberculosis and Mycobacterium avium complex. 3-Aminopyrrolidin-2-one hcl has a broad spectrum of activity against gram positive and gram negative bacteria, but it is not active against acid-fast bacteria.</p>

<p>Versatile small molecule scaffold</p>

<p>FG-2216 is a peptide that activates the G protein-coupled receptor, leading to increased intracellular calcium. FG-2216 is a potent agonist of the GPRC6A receptor and has been shown to inhibit pain perception in animal models. FG-2216 has been shown to have no effect on ion channels and does not affect cellular proliferation or migration. FG-2216 may be useful as a research tool for studying the function of the GPRC6A receptor in animal models.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(1R,2S)-2-Phenylcyclopropane-1-carboxylic acid is a dicarboxylic acid that is produced from the decarboxylation of benzyne. This compound has been shown to be a precursor of benzene and ozonolysis. The stereospecifically of (1R,2S)-2-Phenylcyclopropane-1-carboxylic acid has been determined using lead tetraacetate as the substrate. (1R,2S)-2-Phenylcyclopropane-1-carboxylic acid is an asymmetric molecule.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>tert-Butyl 2-bromo-2-methylpropanoate is a versatile compound with various applications. It is commonly used as a cytotoxic agent in the pharmaceutical industry and as an amide intermediate in organic synthesis. This compound has also been studied for its potential therapeutic effects, such as its ability to inhibit the growth of cancer cells. tert-Butyl 2-bromo-2-methylpropanoate is often utilized in research settings to study the efficacy of drugs like rabeprazole and tripterygium. Additionally, it finds applications in the production of polymers, catalysts, and hydrogen atom transfer reactions. With its wide range of uses, tert-Butyl 2-bromo-2-methylpropanoate is a valuable compound for researchers and industries alike.</p>

<p>2,3-Dihydro-1H-pyrrolo[3,2-c]pyridine is an alkaloid compound that has various applications in research and chemical studies. It has been found to interact with dopamine receptors and exhibit photothermal properties. This compound has been studied in the context of G. lucidum (also known as Reishi mushroom) and its potential therapeutic effects. Additionally, it has shown interactions with quinpirole, lithium, ergovaline, efrotomycin, and other compounds. The photocatalytic and fatty acid properties of 2,3-Dihydro-1H-pyrrolo[3,2-c]pyridine make it a versatile compound for various research purposes.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Morpholin-4-yl)acetyl chloride hydrochloride is a fine chemical that is used as a building block for the synthesis of other compounds. It can be used in research and development, or as a reagent. 2-(Morpholin-4-yl)acetyl chloride hydrochloride has high purity and is easily soluble in water. This compound can be used as an intermediate to synthesize other compounds, or it can be used as a scaffold for the formation of complex structures.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Iridium(III) bis-(2-phenylpyridine) (Ir{dFCF3ppy}2(bpy)) is a monomeric amido ligand that can be used in polymerization processes. It has an average molecular weight of 185.8 and a transition temperature of -55°C. Ir{dFCF3ppy}2(bpy) is soluble in organic solvents such as chloroform and acetone and will react with amines, anionic sites, and cycloalkyl groups to form polymers. The yields of the polymerization process are dependent on the starting materials used.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Pentanimidamide hydrochloride is a drug that belongs to the group of aromatic hydrocarbon drugs. It is a potent antihypertensive agent with a rapid onset and long duration of action. Pentanimidamide hydrochloride has been shown to inhibit the production of reactive oxygen species, which are generated by the respiratory chain in mitochondria, and to prevent the formation of pyrazinoic acid, an inhibitor of blood vessel relaxation. This drug also has been shown to reduce blood pressure in animal models by binding to specific receptors on cells in the cardiovascular system. The active form is bound to plasma proteins such as albumin and alpha-1-acid glycoprotein, which are found in high concentrations in erythrocytes. Pentanimidamide hydrochloride also binds to alkynyl groups and phenyl groups, which may be due to its ability to form covalent bonds with these functional groups.</p>

<p>1-(Piperazin-1-yl)butan-1-one is a neoplastic cell growth inhibitor that inhibits the proliferation of myeloid, k562 and HL60 cells. It has been shown to inhibit the growth of tumor cells in vitro. 1-(Piperazin-1-yl)butan-1-one is an analog of piperazine, which is known to be a cytotoxic agent with anticancer activity. The mechanism of action is not known, but it may be due to its ability to inhibit DNA synthesis or its inhibition of protein synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about 8-Methylnonan-1-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about Dibromoethane-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-5-cyano-3-methylbenzoic acid is a diester of methylamine. It is an acid ester that has been used in the synthesis of other compounds. 2-Amino-5-cyano-3-methylbenzoic acid is an intermediate in the synthesis of some pharmaceuticals, such as carbamazepine and methylphenidate. This compound has not been shown to have any biological activity.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-3-methoxypropanoic acid hydrochloride is a mitochondrial enzyme inhibitor that is used as a research tool to study protein synthesis. It binds to the cytochrome b2 subunit of the mitochondrial respiratory chain, inhibiting the oxidation of pyruvate and affecting the production of ATP. 2-Amino-3-methoxypropanoic acid hydrochloride has been shown to induce apoptosis in human liver cells by triggering caspase 3, which is an important enzyme in the apoptotic pathway. 2-Amino-3-methoxypropanoic acid hydrochloride also has a number of chemical properties that make it useful for analytical chemistry. For example, 2-amino-3-methoxypropanoic acid hydrochloride can be used to measure carboxylic acids, acetylation reactions, hydrogen bonds and hydroxyl groups. It can also be used as a nucle</p>

<p>Bromo-PEG3-azide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromo-PEG3-azide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>2-Bromo-3-hydroxy-benzaldehyde is a nitrate that has been shown to have anti-cancer properties. It inhibits the growth of cancer cells by binding to bromodomains in their DNA, thereby preventing transcription and replication. 2-Bromo-3-hydroxy-benzaldehyde also inhibits the production of nitric oxide, which may lead to an inhibitory effect on tumour angiogenesis. The stereoisomers of this compound are used as precursors for the synthesis of ammonium nitrate, which is used as a fertilizer and explosive. 2-Bromo-3-hydroxy-benzaldehyde is also used in organic synthesis as a precursor for acetylation or halide reactions with palladium complexes or halides.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromocyclopentanone is an organic molecule that is used in the synthesis of epoxides. It is also a potential precursor for the synthesis of polymers, dyes, and pharmaceuticals. 2-Bromocyclopentanone has been shown to undergo photolysis when irradiated with ultraviolet light or through chemical reaction with acetonitrile. This product has two conformers with different rotational barriers and corresponding spectral properties. The two conformers can be distinguished by their ultraviolet spectra. The synthetic methods for 2-bromocyclopentanone involve halogenation followed by hydrolysis to yield bromoacetic acid, which is then converted to the desired product by acylation or alkylation.</p>

<p>2-Imidazolidone-4-carboxylic acid is a potent inhibitor of matrix metalloproteinases, which are enzymes that break down proteins in the extracellular matrix. 2-Imidazolidone-4-carboxylic acid inhibits the activity of both serine protease and matrix metalloproteinase, two enzymes involved in the inflammation process. 2-Imidazolidone-4-carboxylic acid has been shown to inhibit the transport of amino acids, leading to decreased protein synthesis and cell growth. It also inhibits cancer cells by disrupting their ability to grow new blood vessels and invade other tissues.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Fipexide is a dopamine analog that is used as an anti-inflammatory drug. Fipexide has been shown to be effective against inflammatory bowel disease, autoimmune diseases and chronic oral toxicity in animal models. The symptoms of fipexide are similar to the symptoms of Parkinson's disease, which include tremors, muscle rigidity and slowness of movement. Fipexide also has a reactive nitrogen atom in its molecular structure, which may contribute to its toxicity. It has been shown to have no effect on locomotor activity in animals with bowel disease.</p>

Please enquire for more information about 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-piperazine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Versatile small molecule scaffold</p>

<p>Poly(dioxanone) is a biocompatible polymer that has been shown to promote bone growth in animal models. It is a cross-linking agent and can be used as an alternative to copper chromite, which is the most common cross-linking agent used in tissue engineering. Poly(dioxanone) has been shown to promote bone growth by stimulating the production of growth factors and increasing the activity of osteoblasts, cells that produce new bone. The material also promotes matrix deposition and remodeling, leading to increased bone density.</p>

<p>Please enquire for more information about 4-Amino-2-mercaptopyrimidine-5-carboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about Lithium orotate monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-(Propan-2-yl)cyclopentan-1-ol is a chemical that belongs to the group of aliphatic alcohols. It has been synthesized in Australia.</p>

<p>Please enquire for more information about 6-Amino-1,2-dihydro-2-thioxo-5-pyrimidinecarboxylic acid sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,2,3,4,5-Pentaphenyl-1'-(di-tert-butylphosphino)ferrocene (Pd(dba)2) is a reagent in the form of a dark brown liquid that can be used to synthesize benzene derivatives. It has been shown to be soluble in chloroform and toluene. This compound is stable at room temperature and it can be eluted with phenyl chloride. Pd(dba)2 is a ligand that binds to the metal palladium in order to facilitate the formation of complex compounds.</p>

<p>2-(4-Methoxy-1H-indol-3-yl)ethan-1-amine is a synthetic compound that belongs to the class of organocatalysts. It is a serotonin receptor agonist, and has been shown to act as an antagonist at the 5HT2AR. This drug has been shown to have stereoselective effects in vitro, with high affinity for the S form of 5HT2AR. 2-(4-Methoxy-1H-indol-3-yl)ethan-1-amine also has some activity against dopamine receptors, but not as much as other compounds in its class. !--[if !supportLists]--&gt;· !--[endif]--&gt;This drug binds to speciogynine and alstovenine receptors, which are part of the opioid system.!--[if !supportLists]--&gt;· !--[endif]--&gt;Modelling studies suggest that 2-(4-M</p>

<p>Versatile small molecule scaffold</p>

<p>4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.</p>

<p>8-Chloro-3,7-dihydro-1H-purine-2,6-dione is a reactive molecule that binds to the active site of bacterial cyclic nucleotide phosphodiesterases and inhibits their activity. This inhibition prevents the breakdown of cAMP and cGMP, which are important second messengers in eukaryotic cells. 8-Chloro-3,7-dihydro-1H-purine-2,6-dione is also a potent inhibitor of protein synthesis and has been used in research studies on wheat leaves.</p>