Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 2-methoxyethanecarboximidate hydrochloride is an amido amide with antibacterial activity. It is a carboxylic acid compound and an isomer of ethyl 2-methylpropanoate. This active form has been shown to inhibit bacterial growth by binding to the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides. The antimicrobial activity of this agent has been demonstrated in vitro against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, Streptococcus pyogenes, and Enterobacter cloacae. Ethyl 2-methoxyethanecarboximidate hydrochloride also inhibits the production of bacterial endotoxin and has shown antibiotic activity against Gram-positive organisms.</p>

<p>9-Oxo-9,10-dihydroacridine-2-carboxylic acid is a fatty acid oxidation product that has been shown to induce apoptosis in the mitochondria of tumor cells. This process is mediated by the release of cytochrome c from the mitochondria into the cytosol. It also binds to antigens in the extracellular matrix and induces autoantibodies against these antigens. 9-Oxo-9,10-dihydroacridine-2-carboxylic acid has been found to bind to caspase family members and potentiate their activity. 9oxoacridine 2 carboxylic acid is also a potential antitumor agent that shows histological evidence of tumor regression in rats injected with sarcoma 180 cells.<br> 9oxoacridine 2 carboxylic acid also binds to DNA and inhibits protein synthesis by blocking transcriptional initiation at G</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-5-nitronicotinic acid is an inhibitor of HIV-1 reverse transcriptase. It binds reversibly to the active site of the enzyme and blocks its ability to synthesize DNA, thus inhibiting HIV replication. 2-Chloro-5-nitronicotinic acid also inhibits the activity of wild type and mutant forms of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with high potency. This drug has been shown to be effective against nevirapine resistant HIV strains. The molecular modeling studies suggest that 2-chloro-5 nitronicotinic acid binds to a hydrophobic pocket in the active site of HIV reverse transcriptase, which is different from other inhibitors such as AZT, ddI, and ddC.</p>

<p>2-Chloro-5-hydroxynicotinic acid is a chemical compound that has been isolated from the bark of the plant Cinchona officinalis. It is an intermediate in the biosynthesis of quinine and other cinchona alkaloids. 2-Chloro-5-hydroxynicotinic acid is also used as an intermediate in the synthesis of other compounds, including herbicides and pesticides.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Benzofuran-2-carbohydrazide (1BFC) is an antibacterial agent that belongs to the class of nitrogenous compounds. It is a member of the benzofuran derivatives and has been shown to have significant antifungal activity against flavus, cleavage activity against s. aureus and staphylococcus, and hypoglycemic activity in mice. 1BFC has been found to be more active than fluconazole against Candida albicans, but less active than fluconazole against Saccharomyces cerevisiae.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Amino-4-methoxynaphthalen HCl is an alkaloid that is synthesised from 1-Amino-4-(N,N-dimethylamino)naphthalene. It is a tetracyclic compound and it has been shown to be effective in the treatment of hypertension and other cardiovascular diseases.</p>

<p>Versatile small molecule scaffold</p>

<p>N/A</p>

<p>2-(2-Methoxyethoxy)benzaldehyde is a fluorescent organic compound that has binding properties to ethylene. It undergoes photophysical and chemosensors reactions, and can be used as a moiety in the synthesis of other compounds. 2-(2-Methoxyethoxy)benzaldehyde can be used as an enhancer for thiazole derivatives, which are metal ion chelators. The enhancement of thiazole derivatives is due to the presence of electron-donating methoxy groups on the benzaldehyde ring. 2-(2-Methoxyethoxy)benzaldehyde also has electrochemical properties that make it useful for the detection of metal ions such as copper ions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Benzoylpyrimidine is an anti-cancer drug that can be used as a monotherapy or in combination with other drugs. It has been shown to have significant activity against cancer cells and tuberculosis. This compound is synthesized by reacting aryl amine with benzoyl chloride in presence of potassium cyanide, followed by hydrolysis of the resulting nitrile. 5-Benzoylpyrimidine has also been shown to inhibit the growth of fungi, such as Candida albicans, Saccharomyces cerevisiae, and Aspergillus niger. The mechanism of action for this drug is not fully understood but may involve inhibition of protein synthesis at the ribosome level or inhibition of mitochondrial function.<br>5-Benzoylpyrimidine also inhibits the growth of bacteria such as Staphylococcus aureus, Enterobacter aerogenes and Klebsiella pneumoniae.</p>

<p>1,2-Dihydro-1,10-phenanthrolin-2-one is a ligand that binds to copper. It has been shown to be a functional group of the copper complex. The 1,2-dihydro-1,10-phenanthrolin-2-one molecule is able to bind to Alzheimer's disease amyloid plaques in vitro and may mediate their removal from the brain. This compound also interacts with metal ions such as copper oxide and phosphorus pentachloride. Mechanistic studies have been conducted using low energy electron diffraction device. Studies have shown that 1,2-dihydro-1,10 phenanthrolin 2 one binds to carboxylic acid groups on enzymes called esterases and inhibits their function by preventing them from binding phosphate groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Ethoxy-4-hydroxy-1,5-naphthyridine-3-carboxylic acid is a condensation product of pyrrolidino, propyl and hydroxylamine. It is an antifilarial agent that inhibits the growth of filaria and filariidae. This compound has shown efficacy in the treatment of cycloalkyl and piperidino nematodes, as well as in the elimination of malonate from the body. 6-Ethoxy-4-hydroxy-1,5-naphthyridine 3 carboxylic acid is also used to treat family members who have been infected with morpholinos.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Methylbenzenesulfonamido)-2-phenylacetic acid is a molecule with two nitrogen atoms in its structure. It contains one carboxylate group and the molecular weight of this compound is 178.22 g/mol. This molecule has a low molecular weight, which makes it a good candidate for use in organic synthesis. It can be produced by reacting ethylene with transition metal ions such as titanium tetrachloride or zirconium tetrachloride. 2-(4-Methylbenzenesulfonamido)-2-phenylacetic acid is resistant to both oxidation and reduction, making it an ideal candidate for use in organic synthesis. 2-(4-Methylbenzenesulfonamido)-2-phenylacetic acid diffracts light at a wavelength of 0.34 nm, making it useful for determining the size and shape of molecules that are crystallized from solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>