Building Blocks

<p>5,6-Dibromoindoline-2,3-dione is a chemical compound that can be used as an anti-cancer drug. It has been shown to inhibit the activity of histone deacetylase enzymes in vitro and in vivo. 5,6-Dibromoindoline-2,3-dione has also been shown to have potential for use in cancer therapy by inhibiting tyrosine kinases and serotonin receptors. This compound is synthesized from indole and bromine. The chemical reactions involved are hydrogen bonding and substitution reactions.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>4-(4-Aminophenyl)benzene-1,2-diamine (4-APB) is a neuroprotective agent that has been shown to protect neurons in vitro against oxidative stress and glutamate toxicity. 4-APB also inhibits the uptake of 4-(4-aminophenyl)benzene-1,2-diamine into cells by inhibiting the enzyme responsible for its synthesis. This inhibition leads to a decrease in cellular levels of 4-(4-aminophenyl)benzene-1,2-diamine and an increase in its concentration outside the cell. It has been shown to be effective against human ovarian carcinoma cells and ascitic cancer cells, but not against cisplatin resistant cancer cells. The mechanism of action of this drug is still unknown.</p>

<p>4-Chloro-2H-chromen-2-one is an organic compound that is used as a building block in the synthesis of coumarin derivatives. It undergoes nucleophilic substitution reactions with amines, forming 4-hydroxycoumarin. This reaction is catalyzed by organometallic compounds such as PdCl2 and Cu(OAc)2. Cross-coupling reactions have been shown to be effective for the synthesis of coumarin derivatives. The mechanism of this reaction involves oxidative addition of an organometallic reagent to the carbon atom, followed by elimination of water to form an intermediate epoxide. Deuteration is required for this reaction because hydrogen reacts too rapidly with the organometallic reagents to be useful in the coupling process. 4-Chloro-2H-chromen-2-one has been shown to react with other nucleophiles such as thiols, phenols, and alcohols at</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Prop-2-en-1-ylsulfanyl)benzoic acid is a phenyl group that has the ability to form a desorption molecule. It is light resistant and photopolymerizable, which means it can be used in the production of polymers. The alkylthio group on this molecule allows for transfer and gel permeation chromatography. 2-(Prop-2-en-1-ylsulfanyl)benzoic acid also has a vinylic group, which makes it hydrosilylation crosslinkable. This makes it an excellent candidate for copolymerization and hydrosilylation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Dimethylaminomethyl-benzoic acid hydrochloride (4DMABAH) is an antiviral agent that inhibits the replication of human immunodeficiency virus type 1 (HIV-1) by blocking the synthesis of viral DNA. 4DMABAH is a prodrug, which is metabolized to its active form, lamivudine, by esterases in the liver and other tissues. 4DMABAH has been shown to be effective against hepatitis B and C viruses in cell culture studies.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Amino-4-methoxynaphthalen HCl is an alkaloid that is synthesised from 1-Amino-4-(N,N-dimethylamino)naphthalene. It is a tetracyclic compound and it has been shown to be effective in the treatment of hypertension and other cardiovascular diseases.</p>

<p>Versatile small molecule scaffold</p>

<p>N/A</p>

<p>2-(2-Methoxyethoxy)benzaldehyde is a fluorescent organic compound that has binding properties to ethylene. It undergoes photophysical and chemosensors reactions, and can be used as a moiety in the synthesis of other compounds. 2-(2-Methoxyethoxy)benzaldehyde can be used as an enhancer for thiazole derivatives, which are metal ion chelators. The enhancement of thiazole derivatives is due to the presence of electron-donating methoxy groups on the benzaldehyde ring. 2-(2-Methoxyethoxy)benzaldehyde also has electrochemical properties that make it useful for the detection of metal ions such as copper ions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Benzoylpyrimidine is an anti-cancer drug that can be used as a monotherapy or in combination with other drugs. It has been shown to have significant activity against cancer cells and tuberculosis. This compound is synthesized by reacting aryl amine with benzoyl chloride in presence of potassium cyanide, followed by hydrolysis of the resulting nitrile. 5-Benzoylpyrimidine has also been shown to inhibit the growth of fungi, such as Candida albicans, Saccharomyces cerevisiae, and Aspergillus niger. The mechanism of action for this drug is not fully understood but may involve inhibition of protein synthesis at the ribosome level or inhibition of mitochondrial function.<br>5-Benzoylpyrimidine also inhibits the growth of bacteria such as Staphylococcus aureus, Enterobacter aerogenes and Klebsiella pneumoniae.</p>

<p>1,2-Dihydro-1,10-phenanthrolin-2-one is a ligand that binds to copper. It has been shown to be a functional group of the copper complex. The 1,2-dihydro-1,10-phenanthrolin-2-one molecule is able to bind to Alzheimer's disease amyloid plaques in vitro and may mediate their removal from the brain. This compound also interacts with metal ions such as copper oxide and phosphorus pentachloride. Mechanistic studies have been conducted using low energy electron diffraction device. Studies have shown that 1,2-dihydro-1,10 phenanthrolin 2 one binds to carboxylic acid groups on enzymes called esterases and inhibits their function by preventing them from binding phosphate groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Ethoxy-4-hydroxy-1,5-naphthyridine-3-carboxylic acid is a condensation product of pyrrolidino, propyl and hydroxylamine. It is an antifilarial agent that inhibits the growth of filaria and filariidae. This compound has shown efficacy in the treatment of cycloalkyl and piperidino nematodes, as well as in the elimination of malonate from the body. 6-Ethoxy-4-hydroxy-1,5-naphthyridine 3 carboxylic acid is also used to treat family members who have been infected with morpholinos.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>2-(4-Methylbenzenesulfonamido)-2-phenylacetic acid is a molecule with two nitrogen atoms in its structure. It contains one carboxylate group and the molecular weight of this compound is 178.22 g/mol. This molecule has a low molecular weight, which makes it a good candidate for use in organic synthesis. It can be produced by reacting ethylene with transition metal ions such as titanium tetrachloride or zirconium tetrachloride. 2-(4-Methylbenzenesulfonamido)-2-phenylacetic acid is resistant to both oxidation and reduction, making it an ideal candidate for use in organic synthesis. 2-(4-Methylbenzenesulfonamido)-2-phenylacetic acid diffracts light at a wavelength of 0.34 nm, making it useful for determining the size and shape of molecules that are crystallized from solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Isopropylpyrazole-5-carboxylic acid is a luminescent compound that has been used as a ligand for europium. It has been shown to bind the metal and form a fluorescent complex. This compound is also able to act as an electron-accepting substrate for carboxylate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>The 6-(benzyloxy)-3-methyl-1H-indole is a hydrogenolysis debenzylation byproduct and a catalytic byproduct. It can be used to produce benzaldehyde, an aromatic aldehyde that is used in the production of various flavors and fragrances.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-2-methoxybenzoic acid methyl ester is a chlorinated aromatic compound that can be used as an herbicide. It reacts with electron donors to form a radical anion, which transfers its negative charge to the electron acceptor. 3-Chloro-2-methoxybenzoic acid methyl ester is toxic and should be handled with care. It has been shown to inhibit photosynthesis in plants, which may lead to environmental damage. 3-Chloro-2-methoxybenzoic acid methyl ester also has the potential to release chloride ions into the environment, which can cause transfer reactions with other substances that are present in the environment.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Bromo-6-methylpyridine-2-carbonitrile is a chiral compound. It has been used as a raw material to produce various organic compounds, such as enantiomers and optical isomers. 3-Bromo-6-methylpyridine-2-carbonitrile can be prepared by cross coupling reaction with an optically active boronic acid or ester in the presence of a base. The optical purity of the molecule can be determined using either preparative high performance liquid chromatography (prep HPLC) or dichroism spectroscopy.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>