Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-(Methylsulfonyl)-1H-indole is a heterocyclic compound with a six-membered indole ring. It has hydrophilic properties and is soluble in water, alcohols, ethers, chloroform, benzene, and carbon tetrachloride. 6-(Methylsulfonyl)-1H-indole can be used as an anti-inflammatory agent that selectively inhibits cyclooxygenase (COX) enzymes COX-2. This compound has been shown to have potent activity against human COX-2 enzyme. 6-(Methylsulfonyl)-1H-indole binds to the active site of COX enzymes by forming hydrogen bonds with amino acid residues and by occupying the hydrophobic pocket of the enzyme. The conformationally constrained nature of this compound may account for its selectivity for COX-2 inhibition over COX-1 inhibition.</p>

<p>2-Chloro-5-fluoro-4-methoxy-6-methylpyrimidine is a drug candidate that has been optimized for potency and selectivity. It has been shown to have high affinity for the BACE1 enzyme in nonhuman primates, with a time-dependent profile. This compound has also been validated in monkeys and is being considered for medicinal chemistry optimization by Pfizer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Amino-1H-indole-2-carbonitrile (3AIC) is a chemical compound that is a byproduct of the production of indigo dye. It can be used as an efficient and inexpensive reagent for the synthesis of organic compounds, such as amino acid derivatives. 3AIC is soluble in water at high temperatures, but insoluble in water at low temperatures. The solubility of 3AIC in water can be increased by adding ionic liquids to the solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Difluoromethoxy)-5-nitropyridine is a reagent that is used in organic synthesis. This compound is synthesized by the reaction of 2-fluoro-5-nitrobenzaldehyde with difluoromethylmagnesium bromide. The yields for this compound are high and it can be used as a starting material for various chemical reactions, such as formylations, nucleophilic aromatic substitutions, or sulfonylations. The synthesis of 2-(difluoromethoxy)-5-nitropyridine involves an electrophilic substitution at the C2 position of the pyridine ring with the trifluoromethyl group to produce a fluorine atom. The mechanism of this reaction is catalysed by strong bases, such as potassium fluoride.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl-pseudouridine-5'-triphosphate trisodium is the triphosphate of 1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. UV max wavelength = 272nm</p>

<p>Applications 1,3,5-Trifluorotrichlorobenzene is a useful reagent.<br></p>

<p>Applications 4-Diazobenzenesulfonic acid (cas# 305-80-6) is a useful research chemical.<br></p>

<p>5-bromo-3,3-dimethyl-2,3-dihydro-1H-indole is an activator that is used in palladium catalyzed reactions to form a phosphine ligand. 5-bromo-3,3-dimethyl-2,3-dihydro-1H-indole is also used as a vasotropic agent and reagent for organic synthesis. It is used to synthesize ethylesters and salts of 5-(5'-bromo)-2,2'-dihydroquinoline carboxylic acid. This compound can be hydrolyzed with alkaline solution to produce the corresponding amine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Ethynylbenzenesulfonamide is a synthetic, hydrophobic, antimicrobial compound that disrupts the cell membrane. It has been shown to be effective against both mammalian and microbial cells. The antimicrobial use of this compound is still under study, but it may provide an alternative to the current antibiotics. 3-Ethynylbenzenesulfonamide is amphipathic in nature and has an extremely large expansion ratio. This molecule is also hydrophobic, which may help with its ability to penetrate the cell membrane. Antimicrobial compounds are designed to inhibit or kill microorganisms such as bacteria or fungi by disrupting their cellular membranes. They work by interacting with specific targets on the surface of the target organism and producing a lethal effect on its function. 3-Ethynylbenzenesulfonamide interacts with proteins found on bacterial membranes called porins, resulting in a loss of osmotic stability and then permeability through the bilayer. This leads</p>

<p>7-Bromo-1-methylnaphthalene is a fluorescent dye that can be used to measure the concentration of DNA, RNA, and proteins. This compound is an intercalator, which means that it can bind to double stranded DNA or RNA near the center of the molecule where there is a space for binding. It has been used in the study of the thymic gland because it binds to DNA and RNA in cells from this organ. 7-Bromo-1-methylnaphthalene has also been used as a skeleton for organic compounds, such as dimethylammonium. The bromine atom in this compound can be replaced with other atoms like iodine or chlorine to make different colored dyes.</p>

<p>Versatile small molecule scaffold</p>

<p>Di(1-adamantyl)chlorophosphine is a bifunctional ligand that can be used for the palladium-catalyzed coupling of aryl chlorides and amines. Di(1-adamantyl)chlorophosphine is synthesized from adamantane, phosphorous pentachloride, and anhydrous ammonia in the presence of catalytic amounts of palladium. Di(1-adamantyl)chlorophosphine is immobilized on silica gel to prevent hydrolysis. This ligand reacts with primary amines to form iminophosphoranes, which can then be reacted with aryl chlorides to form aryl chloroamines.</p>

<p>1,3,5,7-Tetrabromoadamantane is a molecule that has been synthesized and introduced as a mediator to introduce oxidants. The introduction of the oxidant is mediated by 1,3,5,7-tetrabromoadamantane. This molecule has been shown to be synthesized in two steps from hexamethylenetetramine (HMT) and iodomethane. The synthesis of this molecule can also be achieved by reacting synthons such as tetraphenylmethane with hydrochloric acid. 1,3,5,7-Tetrabromoadamantane is an equivalence mediator because it can mediate a redox reaction in which the oxidizing agent is reduced and the reducing agent is oxidized.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Carbamoyl linagliptin is a synthetic drug that is a selective, reversible inhibitor of dipeptidyl peptidase-4 (DPP-4), an enzyme that breaks down the incretin hormones GLP-1 and GIP. This drug has been shown to help control blood glucose levels in patients with type 2 diabetes. It binds to the active site of DPP-4 and prevents it from breaking down GLP-1 and GIP, which leads to increased levels of these hormones in the body. N-Carbamoyl linagliptin has a long half life, making it suitable for once daily administration. It also lacks any significant interactions with other drugs or foods.</p>

<p>Used in the preparation of metal-diene reagents (e.g. for carbocyclization)</p>

<p>2,2'-Dithiodianiline is a redox-active molecule with a redox potential of -0.08 V. It has been shown to inhibit the polymerase chain reaction by binding to DNA and inhibiting the enzyme DNA polymerase. 2,2'-Dithiodianiline is a potent inhibitor of bacterial growth in vitro, and has been shown to be cytotoxic in vivo. 2,2'-Dithiodianiline inhibits the growth of resistant mutants that are resistant to other antibiotics such as penicillin and ampicillin. This compound binds to molybdenum at an optimum concentration of 0.5 mM and coordinates through electrostatic interactions with the molybdenum atom. Structural analysis reveals that 2,2'-dithiodianiline forms hydrogen bonds with adenine residues in DNA and interacts with guanine residues in RNA through π-π stacking interactions. This interaction prevents transcription by blocking the binding</p>

<p>4,4'-Dimethyl-2,2'-bipyridine is a molecule that belongs to the group of p2 metal complexes. It has been shown to have synergistic effects with ruthenium complexes in analytical chemistry and electrochemical studies. Theoretical calculations have been performed for 4,4'-dimethyl-2,2'-bipyridine and its derivatives. These calculations show that the molecule is planar and that it can be considered as a diazonium salt. The photochemical properties of 4,4'-dimethyl-2,2'-bipyridine have also been studied in detail. This substance emits light when excited by ultraviolet light or visible light, which makes it an excellent candidate for use as a luminescent material in optical displays.</p>

<p>2,4-Dibromopyridine is a brominated derivative of pyridine. It is synthesized through the substitution of two bromine atoms for two hydrogens on the pyridine ring. This synthesis can be achieved by disubstitution or cross-coupling reactions. The reaction products are nucleophilic and react with electrophiles to produce substitution products. The reaction mechanism is thought to involve a six-membered transition state, which has been observed using X-ray absorption spectroscopy.</p>

<p>2,4-Dimethyl-3-hydroxypyridine is a hydroxypyridine compound with epoxide. It inhibits cytochrome P450 enzymes and is used as an organic solvent. 2,4-Dimethyl-3-hydroxypyridine is also used in research to study the structure of the pyridine ring and the hydroxyl group.</p>

<p>2,5-Dibromopyridine is a chemical compound that can be used as a coupling agent in palladium-catalyzed cross-coupling reactions. It is used on the surface of metal particles to increase the efficiency of the reaction, and has been shown to react with substrates such as sodium hydroxide solution, sodium carbonate, halides and hydroxides. 2,5-Dibromopyridine also reacts with benzoate to form a palladium complex. 2,5-Dibromopyridine can be used as an oxidant or reductant depending on the type of reaction it is being used in. It has redox potentials at -0.6 volts for oxidation and +0.6 volts for reduction.</p>

<p>3-Chloro-5-iodobenzoic acid methyl ester is a versatile building block that can be used to make many complex compounds, including research chemicals and reagents. 3-Chloro-5-iodobenzoic acid methyl ester is used as an intermediate for the production of speciality chemicals and has many uses in chemical reactions. This compound was previously sold under the CAS number 289039-85-6.</p>

<p>2-Chlorobenzonitrile is a white solid that is soluble in organic solvents. It is an aryl halide and has a chemical structure of C6ClCN. 2-Chlorobenzonitrile is used as a raw material for the production of dyes and pharmaceuticals. This compound reacts with hydrochloric acid to form 4-chlorobenzonitrile, which can be used in the synthesis of other chemicals. 2-Chlorobenzonitrile can also react with n-dimethyl formamide in an optimal reaction solution to form 4-chlorobenzonitrile. The FTIR spectroscopy on this compound shows that it has a chloride group at 795 cm−1. The optimum reaction temperature for this compound is between 100 and 120 °C, but it will react with inorganic acids such as sulfuric acid or phosphoric acid at higher temperatures. Synthesis of this compound can be done by reacting</p>

<p>(-)-Corey lactone diol is a synthetic compound that is soluble in organic solvents. It is used for the synthesis of carbocyclic nucleosides, which are analogs of pyrimidine nucleosides. (-)-Corey lactone diol has been shown to inhibit cholesterol synthesis and the synthesis of alkene. (-)-Corey lactone diol also shows anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>4-Chloro-8-quinolinol is a quinoline derivative that has been shown to have pharmacological effects. It is used in the synthesis of other compounds, such as 5-chloro-8-hydroxyquinoline, which is used in the treatment of cancer. 4-Chloro-8-quinolinol can also be prepared by oxidizing 5,6,7,8 tetrachloroquinoline with chlorine and ammonia. The photophysical properties of this compound are analogous to those of benzothiazole derivatives. The fluorescence emission spectrum ranges from 360 nm to 450 nm with a maximum at 390 nm and emission intensity at 350 nm. This compound exhibits fungitoxicity against Penicillium notatum and Aspergillus fumigatus.</p>

<p>1,4-Benzenedicarboxylic acid, monoethyl ester (1,4-BDE) is a monomer that is used in the manufacture of polycarbonates and other plastics. 1,4-BDE is also used as a solvent for xylene and butanol. It has been shown to be useful in the production of polyester fibers. The monomer can be synthesized by reacting ethylene with terephthalic acid or dimethyl terephthalate (DMT). This reaction produces 1,4-BDE and methanol as byproducts. The process is carried out at temperatures of 250 °C to 300 °C and under atmospheric pressure. The purified product can be isolated using distillation or extraction with organic solvents such as benzene or butanol. The reaction can be carried out in the presence of ruthenium, which acts as a catalyst.</p>

<p>1-Bromo-4-iodobenzene is an aryl halide that can be synthesized by the cross coupling of ethyl formate and hydrochloric acid. This compound is useful in analytical applications, such as chromatographic methods, due to its high solubility in organic solvents. It is also used in synthetic procedures for the preparation of other aryl halides. 1-Bromo-4-iodobenzene has been used to synthesize calcium carbonate via the Suzuki coupling reaction with sodium salts, which are nucleophiles. The carbonyl group on this molecule reacts with the nucleophile, forming an alkyl group and a metal salt. Transfer reactions involving these salts can produce other products with different functional groups.</p>

<p>Boc-Tyr(tBu)-OH is a chemical compound that is part of the class of lactams. It has been shown to have antitumor activity in vitro and in vivo, but it has not yet been tested for its cytotoxicity. This compound is synthesized by solid-phase synthesis and contains a disulfide bond, which may contribute to its cytotoxicity. Boc-Tyr(tBu)-OH has also been shown to have high affinity for the alpha 2A adrenergic receptor subtype and other receptors with an isosteric carbonyl group.</p>

<p>Please enquire for more information about 6-Bromo-4-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Bisaboloxide A including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Bromo-5-hydroxypyridine is an aromatic compound that is used in the synthesis of a variety of pharmaceuticals and other organic compounds. It can be synthesized by the Suzuki coupling reaction from 2-bromobenzaldehyde and 5-aminopyridine. 2-Bromo-5-hydroxypyridine has been shown to be a hepatotoxin in humans, with possible carcinogenic activity. It also has cholinergic properties, as well as being able to cause fluorescence when exposed to halogens. The carbon next to the hydroxyl group is a stereocenter, so there are two different configurations for this molecule. The configuration shown above (R) is the more stable form of this molecule due to its electron withdrawing power on the neighboring oxygen atom.</p>

<p>3-Bromo-4-nitropyridine is a pyridine compound that has been identified as an environmental contaminant. It is used to synthesize other compounds, such as 4-(3-bromopyridin-2-yl)morpholine, which is used in the synthesis of acetonitrile. 3-Bromo-4-nitropyridine undergoes nucleophilic substitution reactions with amines, leading to homoconjugation and bond cleavage. This reaction may be followed by nitration to give 3-(3'-nitro)pyridine. 3-Bromo-4-nitropyridine can be converted into its n-oxide form or into the ionic form by treatment with acetonitrile.</p>

<p>Diethyl Acetylphosphonate is a synthetic chemical that is used in the production of ethyl esters, which are used as intermediates for the production of epoxides. It has shown to be a bidentate ligand and reacts with primary amines. Diethyl Acetylphosphonate can be made by reacting phosphorus pentachloride with ethyl acetate and hydrochloric acid. The reaction mechanism is similar to that of other organophosphorus compounds, in which a phosphine oxide intermediate reacts with an organic halide. Diethyl Acetylphosphonate has shown to be effective in detergent compositions and triethyl orthoformate, as well as alkanoic acid.</p>

<p>Please enquire for more information about 5-Bromo-2-fluoro-1,3-dimethylbenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Bromo-2-fluoro-6-methylpyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Amino-3-methylisothiazole HCl is a pyridine-5-carboxylic acid that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to inhibit the growth of both aeruginosa and nalidixic acid resistant strains of S. aureus, P. aeruginosa, and P. mirabilis in vitro. 5-Amino-3-methylisothiazole HCl has also been shown to be active against E. coli, quinolone resistant strains of Proteus mirabilis, and methicillin resistant strains of Staphylococcus aureus in vitro.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,4,5-Trimethoxybenzoyl Chloride is a reactive, active chemical that is used in the synthesis of cytotoxic amides. It is prepared by reacting 3,4,5-trimethoxybenzoic acid with an amine or ammonia in the presence of a base. The reaction yields an amide substituted at the 3- and 4-positions with trimethoxyphenyl groups.</p>

<p>2-Bromo-5-fluoro-4-nitroaniline can be synthesized in a reaction system of ammonium chloride, hydrochloric acid, and water vapor. The reaction is carried out at a temperature of 190°C under reflux. The efficiency of this synthesis is high, and the chemical yield is about 90%.</p>

<p>Versatile small molecule scaffold</p>