Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Thienopyridone is a drug that belongs to the class of pharmacological agents. It is synthetically produced and has been found to activate AMPK, an enzyme which plays a role in cellular physiology. Thienopyridone activates AMPK by inhibiting its phosphatase activity, thereby increasing the metabolic rate. Thienopyridone also inhibits fatty acid synthesis, leading to hepatic steatosis and metabolic disorders.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(2,3-Dihydro-1H-indol-1-yl)-2-(piperazin-1-yl)ethan-1-one is a potent and selective small molecule inhibitor of the G protein coupled receptor (GPCR), β2AR. The compound binds to the β2AR with nanomolar affinity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl-pseudouridine-5'-triphosphate trisodium is the triphosphate of 1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. UV max wavelength = 272nm</p>

<p>Applications 4-Diazobenzenesulfonic acid (cas# 305-80-6) is a useful research chemical.<br></p>

<p>Applications 1,3,5-Trifluorotrichlorobenzene is a useful reagent.<br></p>

<p>2-Acetylbenzoic acid is a functional molecule that contains an acetyl group. It can form hydrogen bonds with other molecules and has been shown to induce apoptosis in cells. The reaction products of 2-acetylbenzoic acid are malonic acid, acetylsalicylic acid, and 2-benzoylbenzoic acid. These three compounds are made by the addition of hydrogen or hydroxide to the molecule 2-acetylbenzoic acid. The molecule has two functional groups: a carbonyl group and an acetyl group. The chemical structure of this molecule can be seen in the figure below.<br>2-Acetylbenzoic Acid</p>

<p>1-Adamantane carboxylic acid is a hydrophobic molecule that can form a complex with metal hydroxides. It is used in the process optimization of the synthesis of sodium salts. 1-Adamantane carboxylic acid binds to metals, such as magnesium and calcium, in a coordination geometry that is similar to that observed for water molecules. The complexation of 1-Adamantane carboxylic acid with metal ions results in an acidic environment, which is important for bowel disease. This acid complex also has anti-inflammatory properties. The hydroxyl group on the 1-adamantane carboxylic acid reacts with oxygen to form an alcohol group and this reaction mechanism may be involved in physiological functions.</p>

<p>2-Amino-4-bromopyridine is a potent, selective antagonist of the nicotinic acetylcholine receptor (nAChR) that has been shown to inhibit the proliferation of cancer cells in vitro. 2-Amino-4-bromopyridine binds to the nAChR and stabilizes it by binding to an allosteric site on the receptor. 2-Amino-4-bromopyridine is synthesized from 4,5-dibromobenzene and 2,6-diaminopyridine in two steps with a yield of 47%. The synthesis of 2-amino-4-bromopyridine proceeds via reaction mechanism involving electrophilic substitution at the bromine atom followed by nucleophilic addition at the nitrogen atom.</p>

<p>9-Anthracenemethanol is a carcinogenic, mutagenic, and teratogenic compound. It is metabolized by a number of enzymatic reactions, including oxidation by cytochrome P450 enzymes and reduction by glutathione reductase. The compound has been shown to be activated in acid conditions, with an activation energy of 10 kcal/mol. It also forms an acid when heated, which can cause damage to cells. 9-Anthracenemethanol has been shown to have photochemical properties that may be used for the production of dyes or pigments.</p>

<p>5-Amino-3-methylisothiazole HCl is a pyridine-5-carboxylic acid that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to inhibit the growth of both aeruginosa and nalidixic acid resistant strains of S. aureus, P. aeruginosa, and P. mirabilis in vitro. 5-Amino-3-methylisothiazole HCl has also been shown to be active against E. coli, quinolone resistant strains of Proteus mirabilis, and methicillin resistant strains of Staphylococcus aureus in vitro.</p>

<p>Please enquire for more information about L-Arginine-7-amido-4-methylcoumarin hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Acetamidobenzenesulfonamide is a drug that inhibits the activity of several enzymes and is used in wastewater treatment. It has been shown to have a beneficial effect on metabolic disorders, such as insulin resistance, obesity, and type 2 diabetes. 4-Acetamidobenzenesulfonamide also regulates transcriptional activity by inhibiting the interaction between DNA and RNA polymerases. This drug has been shown to be active in treating autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis, lupus erythematosus and Crohn's disease. It also aids in HIV infection by acting as an inhibitor of toll-like receptor signalling pathways. The drug binds to hydrogen bonds and hydrophobic interactions with water molecules to form a hydrophobic layer on the surface of cells in order to reduce water permeability. The drug also reduces bowel diseases such as ulcerative colitis and liver lesions caused by alcohol consumption or congestive</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about (3R,4R)-3-[(6-Amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-piperidinepropanenitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl Pyridin-3-ylacetate is an organic compound that is the methyl ester of pyridine-3-carboxylic acid. It has a melting point of 197°C, with an ionization potential of 1.78 eV and a lactam. Methyl Pyridin-3-ylacetate has been shown to react with hydrochloric acid to form picric acid and methyl 3-(hydroxymethyl)pyridine-2,5-dicarboxylate. Methyl Pyridin-3-ylacetate can be used in the preparation of picrates, which are used in the synthesis of dyes and explosives such as picric acid and TNT. Methyl Pyridin-3-ylacetate can also be demethylated by heating with sodium methoxide to give methyl pyridine carboxylate.</p>

<p>Please enquire for more information about 6-Amino-3-pyridinethiol dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,4-Dimethylphenyl isothiocyanate (DMIT) is a dipole molecule that has been used as a preservative and antimicrobial agent. DMIT has been shown to be an effective anti-microbial agent against Gram-positive bacteria such as Staphylococcus aureus, Enterococcus faecalis, and Streptococcus pyogenes. It also inhibits the growth of Gram-negative bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae. DMIT has been shown to be non-toxic to animals at high concentrations. It is also safe for use in food products because it does not react with polyunsaturated compounds.</p>

<p>2-Aminoimidazole sulfate is a chemical compound that is used as a transfection reagent. It has been shown to have high transfection efficiency with low cytotoxicity. The diameter of the molecule is in the range of 2 - 3 nm, which allows it to be taken up by cells and thus be active in them. This chemical can be dehydrogenated to form imidazole-2-sulfonic acid, which may interact with other molecules. There have been many advances in this area, including modifications and gaseous forms of the molecule. Research into the interactions of this compound with other chemicals and their effects on cellular uptake are ongoing.</p>

<p>1,4-Benzenedicarboxylic acid, monoethyl ester (1,4-BDE) is a monomer that is used in the manufacture of polycarbonates and other plastics. 1,4-BDE is also used as a solvent for xylene and butanol. It has been shown to be useful in the production of polyester fibers. The monomer can be synthesized by reacting ethylene with terephthalic acid or dimethyl terephthalate (DMT). This reaction produces 1,4-BDE and methanol as byproducts. The process is carried out at temperatures of 250 °C to 300 °C and under atmospheric pressure. The purified product can be isolated using distillation or extraction with organic solvents such as benzene or butanol. The reaction can be carried out in the presence of ruthenium, which acts as a catalyst.</p>

<p>6-Chlorohexanol is a fatty alcohol with a hydroxyl group. It is soluble in water and has a phase transition temperature of -114°C. 6-Chlorohexanol can be synthesized by reacting 2,6-dichlorophenol with hydrochloric acid and sodium hydroxide in the presence of azobenzene. The reaction solution is then heated to about 300°C for 3 hours. 6-Chlorohexanol is used as a model system for studying the photochemical reactions of fatty acids. Hydroxy groups are susceptible to light exposure, which leads to the formation of carbonyl compounds such as malonic acid and chloride monomers.</p>

<p>R-(-)-3-Chloro-1,2-propanediol is a chiral epoxide that is used in the synthesis of other chemicals. It has been shown to be active against bacterial strains such as corynebacterium and coryneform bacteria. This chemical can be synthesized from hydrochloric acid and chlorinated propane with an asymmetric synthesis. The R-(-)-3-Chloro-1,2-propanediol can also be synthesized through electrochemical methods using chloride ion as the reducing agent. This compound is soluble in water and shows kinetic activity with carbon sources when used as an antibiotic.</p>

<p>Please enquire for more information about H-beta-Cyclohexyl-Ala-OMe·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chloroiodomethane is a chemical that is used as an intermediate in the production of other chemicals. It is a colourless liquid with a strong odour. 3-Bromopropylamine hydrobromide reacts with chloroiodomethane to form 3-bromopropyl bromide, which can be reacted with hydrogen chloride to form the corresponding acid chloride. This reaction product can then be reacted with β-amino acids to form amides or esters. The reaction mechanism of this process involves nucleophilic substitution of chloroiodomethane by the amino group of the β-amino acid to produce an intermediate α,β-unsaturated carbonyl chloride, which undergoes elimination to give the final product. Chloroiodomethane also reacts rapidly with fatty acids and hydroxyl groups in biological systems, leading to inflammatory diseases such as HIV infection.</p>

<p>Cyclobutanethiol is a 1-cyclopentene-1-carboxylic acid, which is a cyclic form of the alkylthio group. It is an organic solvent with a hydroxyl group at one end and an alkyl group at the other end. Cyclobutanethiol can be used as a sealant or as a solvent in organic chemistry. The compound has been shown to inhibit insulin resistance by binding to cb1 receptors on cells, thereby inhibiting the production of glucose. Cyclobutanethiol also absorbs ultraviolet light, so it can be used in photochemistry.</p>

<p>4-Chloro-8-quinolinol is a quinoline derivative that has been shown to have pharmacological effects. It is used in the synthesis of other compounds, such as 5-chloro-8-hydroxyquinoline, which is used in the treatment of cancer. 4-Chloro-8-quinolinol can also be prepared by oxidizing 5,6,7,8 tetrachloroquinoline with chlorine and ammonia. The photophysical properties of this compound are analogous to those of benzothiazole derivatives. The fluorescence emission spectrum ranges from 360 nm to 450 nm with a maximum at 390 nm and emission intensity at 350 nm. This compound exhibits fungitoxicity against Penicillium notatum and Aspergillus fumigatus.</p>

<p>4-Chlorobenzenethiol is a chemical compound that contains a fatty acid. It is an intramolecular hydrogen donor with the ability to form a disulfide bond. The compound also has high stability and can be used in organic synthesis reactions involving reactive sulfur groups. 4-Chlorobenzenethiol reacts with sodium carbonate to produce sodium thiocarbonate and chloroform, which are then reacted with phosphorus pentoxide for oxidation. The reaction mechanism is similar to that of the Diels-Alder reaction and the model system involves dinucleotide phosphate. 4-Chlorobenzenethiol can be reacted with hydrochloric acid or trifluoroacetic acid as an oxidizing agent.</p>

<p>1,1'-Carbonimidoylbis-1H-imidazole is a ligand that binds to amines and isosteres. It can be activated with electrophilic reagents to form an activated linker. This ligand has been shown to inhibit the growth of xenograft tumor cells in mice by binding to functional groups on the cell surface. This drug also has been shown to bind to the receptor for advanced glycation end products (RAGE) and inhibit its function. 1,1'-Carbonimidoylbis-1H-imidazole has also been evaluated as a cancer therapeutic agent in animal models.</p>

<p>2-Chloro-3-(hydroxymethyl)pyridine is an organic compound that is used as a building block for the synthesis of other heterocycles. This compound can be synthesized from 2-chloronicotinic acid, which is obtained by oxidation of nicotine with sodium hypochlorite in the presence of potassium ion. The reaction proceeds via a cleavage of the C-Cl bond and formation of a pyridine ring. The catalytic process can be performed at room temperature and at atmospheric pressure in a variety of solvents, including water.<br>2-Chloro-3-(hydroxymethyl)pyridine has been shown to have high yields for the preparation of compounds such as 2,4-dichloropyridine and 4,5-dichloropyrimidine. It also has been used in the preparation of pharmaceuticals such as atrial natriuretic factor (ANF).</p>

<p>3,5-Dimethylbenzaldehyde is an organic compound that is a colorless liquid. It has a chemical formula of C9H12O2 and is classified as an aldehyde. 3,5-Dimethylbenzaldehyde can be synthesized by the reaction of isopropyl palmitate with xylene in the presence of carbon as a source. The reaction time required for this synthesis is approximately one day. The major products of this reaction are 3,5-dimethylbenzaldehyde and 2-methylbutanal. This reaction mechanism can also be used to determine the concentration of urinary metabolites in human urine samples. Analysis of these samples requires an organic solvent such as hexane or dichloromethane. Kinetic data was collected from the rate at which zinc powder reacts with 3,5-dimethylbenzaldehyde over time at different concentrations. A kinetic experiment was conducted using c–h bond activation to produce 3,5-dimethoxy</p>

<p>3,4-Difluoro-1H-Pyrrole is a neutral compound with a molecular weight of 136.17 g/mol. It has the chemical formula C6H3F2N and it can be found in reactions involving the congener and coordination chemistry. 3,4-Difluoro-1H-Pyrrole is an intermediate in organic synthesis that is used as starting material for other organic compounds such as pharmaceuticals and agrochemicals. The redox potential of 3,4-Difluoro-1H-Pyrrole is -0.42 V for the reaction with chloride solution and its basicity is 0.89 mM at 25°C. This molecule has been studied by X-ray crystallography and by titration calorimetry for hydrogen bonding interactions.</p>

<p>Please enquire for more information about Ethyl 2-(3-phthalimidopropyl)acetoacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Edoxaban impurity G benzenesulfonate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Edoxaban impurity 2 p-toluenesulfonic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethyl 4-bromoacetoacetate is a chemical compound that is used in the synthesis of quinoline derivatives. It also has antiinflammatory properties and can be used to treat inflammatory diseases such as arthritis. The thermal expansion of this compound is greater than that of water, which can be useful in treating respiratory problems by providing increased oxygen transport. Ethyl 4-bromoacetoacetate is a reactive chemical that reacts with hydrochloric acid to produce hydrogen gas and ethyl bromide gas. It also undergoes nucleophilic substitutions at the carbon atom adjacent to the acetoacetate group. This reaction solution can be analyzed using magnetic resonance spectroscopy, which produces data on the sequences of this compound's atoms and its antiinflammatory activity.</p>

<p>Fmoc-Dap(Ac)-OH is a fine chemical that is used as a building block in the synthesis of complex compounds. It reacts with various nucleophiles to form an amide bond, and has been shown to be useful for both research and industrial applications. Fmoc-Dap(Ac)-OH can also be used as a reagent to synthesize peptides, which are biologically active compounds that form the basis of many drugs. This versatile intermediate is also used as a scaffold in the construction of more complex molecules. Fmoc-Dap(Ac)-OH has CAS No. 181952-29-4 and is classified as a speciality chemical by the International Union of Pure and Applied Chemistry (IUPAC).</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydrazinobenzoic acid is a chemical compound that is used as an inhibitor of DNA synthesis. It prevents the formation of hydrogen bonds between nucleotides in DNA, which prevents the synthesis of new DNA strands. 4-Hydrazinobenzoic acid has been shown to inhibit the growth of human breast cancer cells by reactivating the tumor suppressor genes p21 and Rb1, which are responsible for regulating cell cycle progression. This compound also inhibits the production of hydrogen chloride (HCl) in reaction solutions containing sodium hypochlorite (NaOCl).</p>

<p>8-Hydroxyquinoline is a sweet, water soluble, and heat stable inhibitor that has been used in the treatment of kidney disease. 8-Hydoxyquinoline has been shown to inhibit the growth of the rootstock Asiaticus by interfering with cell metabolism. It is also an insecticide that kills insects by causing damage to their cells. 8-Hydoxyquinoline inhibits polymerase chain reaction (PCR) by binding to DNA polymerase, blocking its activity and reducing its ability to synthesize DNA. This drug is also a potent blocker of angiotensinogen synthesis, which leads to reduced blood pressure levels.</p>

<p>Zinc pyrithione is a chemical compound that can be used as an antifungal agent. It has been shown to have genotoxic activity in vitro and in vivo. Zinc pyrithione binds to the surface of the fungal cell wall and inhibits the synthesis of ergosterol, a component of the fungal cell membrane. This binding prevents the formation of an ergosterol-zinc complex with cytochrome P450 enzymes, which are required for sterol biosynthesis, leading to inhibition of energy metabolism. The model system for zinc pyrithione is a mixture of 1-hydroxypyridine-2-thione (1HP) and zinc ions in water. Some studies have shown that zinc pyrithione can cause long-term toxicity, including glycol ether toxicity, when applied topically on hair or skin. Acute toxicities may include skin irritation or contact dermatitis from shampoos containing this substance.</p>

<p>2-Hydroxy-3-mercapto-1-propanesulfonic acid sodium salt (2HMP) is a diagnostic agent that can be used for the detection of bacterial infections. The conformational properties of 2HMP are similar to those of ATP, which allows it to bind to the polymerase chain reaction enzyme and initiate an enzymatic reaction. This leads to the production of a signal that can be detected by spectrophotometry or fluorometry. 2HMP has also been shown to have chemokine activity in vitro, but this has not been tested in vivo. 2HMP is a competitive inhibitor of human protein serine proteases, such as trypsin and chymotrypsin, with an IC50 value of approximately 1 μM.</p>

<p>6-Hydroxy-1-naphthoic acid is a synthetic carboxylate compound with an analog structure that has been shown to be cytotoxic to cancer cells. It inhibits the activity of protein kinases by binding to ATP, which blocks the phosphorylation of tyrosine residues on proteins. 6-Hydroxy-1-naphthoic acid has been shown to inhibit growth factor receptors and induce apoptosis in tumor cells. The mechanism of action for this drug is believed to be through ring opening and hydrolysis of the naphthalene ring, followed by reaction with p-hydroxybenzoic acid. This results in inhibition of histone deacetylase activity, leading to decreased expression of genes involved in cell proliferation.</p>

<p>5-Iodo-2-nitrobenzoic acid is a fine chemical that is used as a building block in the synthesis of complex compounds and research chemicals. This compound has been shown to be an effective reagent for the synthesis of many different types of compounds. It can also be used as a reactant or intermediate in organic syntheses, such as those involving cross-coupling reactions. 5-Iodo-2-nitrobenzoic acid is a versatile building block that can be used in both simple and complex chemical reactions.</p>

<p>4-Iodo-1-methylpyrazole is a reductive agent that is used in organic synthesis. It can be used as a reducing agent for the conversion of aldehydes and ketones to alcohols. 4-Iodo-1-methylpyrazole can be crystallized from diethyl etherate and blood. The product yield from this reaction is high, but it requires an oxidant such as trifluoride or plavix to react with the diacetates. 4-Iodo-1-methylpyrazole can also be synthesized by reacting allylsilanes with iodine gas in the presence of a base. This synthesis method produces 4-iodo-1-methylpyrazole in good yield and with little difficulty.</p>

<p>N-alpha-Z-L-lysine methyl ester hydrochloride is a preparation that is used as a methyl ester. It is an ester of lysine and methyl chloride. This product has a molecular weight of 170.16 g/mol and the chemical formula CH3CONHCH2CH(NH)CO2CH3. The structural data has not been confirmed by X-ray crystallography, but it can be assumed to be in the form of a zwitterion. N-alpha-Z-L-lysine methyl ester hydrochloride can be used for the synthesis of peptides, which are building blocks for proteins and enzymes. N-alpha-Z-L-lysine methyl ester hydrochloride is also used in the production of certain kinds of drugs and organic acids such as acetylsalicylic acid (aspirin).</p>

<p>Leu-Leu-Leu-OH is a pentapeptide that is used in cancer treatment to inhibit the growth of cancer cells. It prevents the production of proteins and, as a result, cell division. Leu-Leu-Leu-OH has been shown to be effective against tumor cells with an antibody that binds to the surface of cells. The monoclonal antibody is taken up by the cancer cells through receptor mediated endocytosis, which leads to inhibition of protein synthesis and cell death.</p>