Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole is a recombinant protein that binds to the ribosomal protein L11. It has been shown to inhibit the biosynthesis of the bacterial cell wall and therefore inhibit replication of the bacterial genome. 3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole also inhibits the synthesis of proteins essential for cell division. This compound has been shown to bind to ribosomes in both prokaryotic and eukaryotic cells. It may have potential as an inhibitor of cancerous cells because it inhibits protein synthesis in mammalian cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Quinoline-5-carbonitrile is a cyanide compound that can be used in the synthesis of heterocyclic compounds. The reaction between quinoline and 5-cyanovaleric acid produces 6-nitroquinoline, which is then converted to dimethyl sulfoxide by alcoholysis. This reaction product can then be used to synthesize an amide or nucleophile. Quinoline-5-carbonitrile reacts with potassium in the presence of bifunctional hydrazide to produce a cyanide ion, which can be hydrolyzed by an acid to release hydrogen cyanide gas. This experiment has been shown as a model for reactions involving cyano compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

4,5-Dihydroxy-2,3-dihydro-1H-isoindole-1,3-dione is a molybdenum compound with a hydroxyl group. It has been shown to inhibit the growth of bacteria that are resistant to penicillin by binding to the penicillin-binding proteins in their cell wall. 4,5-Dihydroxy-2,3-dihydro-1H-isoindole-1,3-dione has been found to be an effective inhibitor of polymer film formation when used in conjunction with 3 chloroperoxybenzoic acid. This compound also has been shown to have anti bacterial properties against Escherichia coli and Pseudomonas aeruginosa. 4,5-Dihydroxy -2,3 -dihydro -1H -isoindole -1,3 -dione may also have environmental applications due its

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(2-Aminophenyl)-1H-pyrazole is a chemical compound that is used in the synthesis of other compounds. It can be produced by various reactions from benzyl chloride and ammonia. The reactivity of 1-(2-aminophenyl)-1H-pyrazole has been studied using single crystal X-ray diffraction. This technique was used to determine the structure and reaction pathway of this molecule as well as to study its catalytic properties. 1-(2-Aminophenyl)-1H-pyrazole is a ligand that binds to metal ions, such as aluminium, in order to form complexes with different functional groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Thienopyridine analogs are a class of chemical compounds that function as agonists of the receptor α. These compounds have been shown to inhibit fatty acid oxidation and ATP production in rat liver cells, which may be due to their ability to activate AMP-activated protein kinase (AMPK). Thienopyridine analogs are being investigated for use as anti-inflammatory agents and cancer treatments.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Bromo-1-hydroxynaphthalene-2-carboxylic acid (4BHN) is a spectroscopic compound that has been used as a radioligand to study the binding of dopamine and dopamine D3 receptors. This compound binds to the d3 receptor with high affinity and specificity, but it does not interact with the d1 or d2 receptors. 4BHN has been shown to act as an agonist at the dopamine D3 receptor. It also acts as an antagonist at the piperidine site of the dopamine D2 receptor. The effects of 4BHN are reversible, which means that it can be displaced by unlabeled 4BHN or other compounds that bind to the same site on the receptor. This technique is useful for studying drug interactions and for determining whether drugs have a subtype selectivity profile.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>PB-22 is a synthetic cannabinoid, which can be classified as a CB1 receptor agonist. It is one of the many cannabinoids that have been created in an attempt to circumvent drug laws by creating compounds that are similar to those found in cannabis but have different chemical structures. PB-22 has shown to increase locomotor activity and stimulate the cb1 receptor in mice. Magnetic resonance spectroscopy (MRS) and assays were used to determine the binding affinity of PB-22 for the CB1 receptor. The MRS data showed that PB-22 bound with high affinity to the CB1 receptor and had a lower affinity for CB2 receptors. This suggests that PB-22 may be more potent than other synthetic cannabinoids, such as JWH-018 and CP 55,940, which bind better with CB2 receptors than CB1 receptors.<br>PB-22 is an analog of JWH-073 and has been shown to have a stronger effect on locomotor activity than JWH</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Benzothiophene-6-carboxaldehyde (BTA) is a heterocyclic compound that contains sulfur. It is a colorless liquid with a sweet odor. BTA is used in the manufacture of pesticides, pharmaceuticals, and other organic chemicals. It is also used as a building block in the synthesis of other compounds and has been shown to have anti-inflammatory properties.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Pyrazolo[1,5-a]pyridin-4-ol is a heteroaromatic compound that acts as an inhibitor of phosphodiesterase (PDE). It prevents the breakdown of cyclic nucleotides and thus leads to increased levels of cAMP and cGMP. Pyrazolo[1,5-a]pyridin-4-ol has been shown to have bronchodilatory activity in animal models. The drug also inhibits the production of inflammatory mediators such as prostaglandins by inhibiting cyclooxygenases. In addition, pyrazolo[1,5-a]pyridin-4-ol has been shown to be a potential PDE inhibitor replacement for the more commonly used PDE inhibitors such as sildenafil and tadalafil. However, due to its lack of stereochemistry and its bicyclic chemical structure, pyrazolo[1,5-a]</p>