Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-butyl methanesulfonate is a genotoxic agent that inhibits the growth of bacteria by binding to the DNA. N-butyl methanesulfonate is effective against typhimurium and has shown carcinogenic effects in hamster cells. N-butyl methanesulfonate is also capable of inhibiting quinoline derivatives, which are carcinogens that are found in tobacco smoke. This chemical can be used as a natural compound for the treatment of diabetic neuropathy and cryptococcus neoformans. It may also be used as an antiviral agent for the treatment of influenza virus.</p>

<p>Versatile small molecule scaffold</p>

<p>Bromo-PEG4-azide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromo-PEG4-azide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Methyl 5-hexynoate is a synthetic product that can be synthesized from soybean lipoxygenase and hydrogenation reduction. This product has been shown to be a useful synthon for the synthesis of monoclonal antibodies with high binding affinity. The synthetic pathway, which involves cross-coupling and asymmetric synthesis, is outlined in the diagram below. The following are the steps involved in the production of methyl 5-hexynoate: 1) Addition of ethyl bromide to terminal alkynes 2) Addition of hydrochloric acid 3) Reaction with potassium tert-butoxide 4) Hydrogenation reduction 5) Cross-coupling reaction 6) Asymmetric synthesis</p>

<p>8-Chlorotetrazolo[1,5-A]pyrazine is a chlorine-containing compound. It is a heterocyclic aromatic organic compound and an important intermediate in the synthesis of other compounds. 8-Chlorotetrazolo[1,5-A]pyrazine is not found in nature. The elimination of chlorine from 8-chlorotetrazolo[1,5-A]pyrazine produces benzotriazole and the molecule tetrazole. 8-Chlorotetrazolo[1,5-A]pyrazine is used as a raw material for many organic syntheses.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Imidazolidone-4-carboxylic acid is a potent inhibitor of matrix metalloproteinases, which are enzymes that break down proteins in the extracellular matrix. 2-Imidazolidone-4-carboxylic acid inhibits the activity of both serine protease and matrix metalloproteinase, two enzymes involved in the inflammation process. 2-Imidazolidone-4-carboxylic acid has been shown to inhibit the transport of amino acids, leading to decreased protein synthesis and cell growth. It also inhibits cancer cells by disrupting their ability to grow new blood vessels and invade other tissues.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Adamantane is a potent antiviral drug for the treatment of influenza. It is an oxidation catalyst that also has biological properties, such as a potent antitumor activity and potent antiviral resistance. Adamantane has been used to treat many human pathogens, including viruses, fungi and bacteria. Adamantane is a skeleton-like structure with four carbons and six hydrogen atoms that can be oxidized to adamantane oxide or reduced to adamantane alcohol. The adamantane molecule binds to the viral protein at a site called the toll-like receptor. This binding prevents viral replication by inhibiting mRNA synthesis in the virus.</p>

<p>2-Amino-6-chloropurine is a nucleophilic substituent that is used in the synthesis of 2-amino-6-chloropurine. It reacts with hydroxyl groups to form a palladium-catalyzed coupling reaction solution, which is then treated with hydrochloric acid and trifluoroacetic acid. The product is purified by crystallization and recrystallization. This compound has potent antitumor activity against carcinoma cell lines, but it has not been shown to have any effect against Mycobacterium tuberculosis.</p>

<p>2-Aminoimidazole sulfate is a chemical compound that is used as a transfection reagent. It has been shown to have high transfection efficiency with low cytotoxicity. The diameter of the molecule is in the range of 2 - 3 nm, which allows it to be taken up by cells and thus be active in them. This chemical can be dehydrogenated to form imidazole-2-sulfonic acid, which may interact with other molecules. There have been many advances in this area, including modifications and gaseous forms of the molecule. Research into the interactions of this compound with other chemicals and their effects on cellular uptake are ongoing.</p>

<p>(1-Pyridin-2-yl)piperidin-4-amine is a drug that acts as an anorexiant. It binds to the serotonin 5HT3 receptor, which is involved in the regulation of appetite and mood. It also blocks the action of serotonin at the 5HT4 receptor, which is involved in mediating intestinal motility. This agent has been shown to have a potent antagonist effect on the 1-4c alkyl group of serotonin receptors. The phenoxy group and methyl group are also responsible for binding with serotonin receptors and blocking their activity.</p>

<p>Please enquire for more information about L-Arginine-7-amido-4-methylcoumarin hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about (3R,4R)-3-[(6-Amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-piperidinepropanenitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about 6-Amino-3-pyridinethiol dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cabozantinib is a small molecule that is the first to target VEGFR-2, which is a receptor tyrosine kinase involved in the development of fibrosis. Cabozantinib inhibits the activity of VEGFR-2 by binding to its ATP-binding site and blocking the phosphorylation of downstream signaling pathways. Cabozantinib has been shown to have antifibrotic properties in both preclinical and clinical models. The drug candidate has been shown to reduce kidney fibrosis in animal models. The standard dose for cabozantinib was found to be 5 mg/kg, with a maximum tolerated dose of 20 mg/kg. In vitro studies have indicated that cabozantinib binds with high affinity to the ATP-binding pocket of VEGFR-2, exhibiting competitive inhibition against other kinases such as PDGFR-beta and cKit, as well as diaryliodonium (a specific inhibitor). Caboz</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl acetate is a reactive intermediate that can be used as a starting material for the synthesis of other organic compounds. It is synthesized by the reaction of an acid with an aldehyde or ketone in the presence of a base. The rate of this reaction depends on the functional groups present in both reactants and their relative concentrations. This intermediate can be converted to another chemical compound through various reactions, including hydroxymethylation, decarboxylation and oxidation. This chemical has been used as a cocatalyst for the production of 5-hydroxymethylfurfural (HMF).</p>

<p>6-Chloro-2-methyl-4-pyrimidinol is an aldehyde that reacts with hydrazine to form a monoxide, which reacts with carbon monoxide to form a hydrazide.</p>

<p>Versatile small molecule scaffold</p>

<p>2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile is a redox molecule that emits light when excited by an electron or photon. It is used in organic light emitting devices (OLEDs) as the emissive material. This compound has been shown to have low chemical stability and limited transport properties. Its efficiency can be improved by increasing the concentration of the molecule. Activated 2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile emits a bright red orange emission with a maximum at 569 nm and it is activated by electron transfer from an electrode. 2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile has been shown to emit blue light when excited by UV light in the presence of oxygen as an oxidant.</p>

<p>Tadalafil is a synthetic drug that is used as a treatment for erectile dysfunction. It works by inhibiting the PDE5 enzyme, which is responsible for breaking down cGMP. Tadalafil has been shown to be effective in the treatment of male erectile dysfunction and pulmonary hypertension, with few side effects. This drug is taken orally, with a meal or without one, and can be administered with or without food. To improve absorption, tadalafil should be taken at least 30 minutes before sexual activity. The dosage of tadalafil ranges from 2.5 to 20 mg, and it should not exceed 40 mg per day.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-benzonitrile is an antibacterial agent that belongs to the group of nitro compounds. It inhibits bacterial growth by blocking the synthesis of proteins and DNA. 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-benzonitrile has been shown to be active against a wide range of bacteria including Gram positive and Gram negative organisms. This compound also exhibits metal ion chelating properties and can be used for the removal of heavy metals from water. The square planar geometry of 2-[(6-Chloro-3,4-(dihydro)-3-(methyl)-2,4-(dioxo)-1</p>

<p>Versatile small molecule scaffold</p>

<p>DSP-4 hydrochloride is a neurotoxin that inhibits the synthesis of norepinephrine. It binds to neurons and prevents the uptake of dopamine, which can lead to neuronal death. DSP-4 hydrochloride affects brain functions by decreasing the concentration of serotonin in the cortex and increasing the concentrations of norepinephrine in the coeruleus. DSP-4 hydrochloride also has estrogenic effects by binding to estrogen receptors and increasing estradiol benzoate concentrations.</p>

L-Alanine methyl ester HCl is a compound that is used in wastewater treatment. It has been shown to inhibit the enzyme DPP-IV, which is associated with metabolic disorders. L-Alanine methyl ester HCl also has been shown to have antimicrobial activity against a number of bacteria, including methicillin resistant Staphylococcus aureus (MRSA). L-Alanine methyl ester HCl has been shown to have anti-inflammatory properties and can be used for the treatment of autoimmune diseases. This compound also has a significant effect on biological properties such as phase transition temperature and thermal expansion.

<p>Cyclobutanesulfonyl chloride is a reagent that is used for the synthesis of 1-6-alkylcyclobutanes. It can be used to synthesize heterocyclic compounds, including those with high optical purity. Cyclobutanesulfonyl chloride has been shown to have antiviral and antiproliferative properties. It has also been shown to exhibit anticancer activity in vitro and in vivo. The mechanism of action for this compound is unclear, but it may inhibit protein synthesis by attacking the amino acid methionine in proteins or by inhibiting DNA replication.</p>

<p>4-Chloro-8-quinolinol is a quinoline derivative that has been shown to have pharmacological effects. It is used in the synthesis of other compounds, such as 5-chloro-8-hydroxyquinoline, which is used in the treatment of cancer. 4-Chloro-8-quinolinol can also be prepared by oxidizing 5,6,7,8 tetrachloroquinoline with chlorine and ammonia. The photophysical properties of this compound are analogous to those of benzothiazole derivatives. The fluorescence emission spectrum ranges from 360 nm to 450 nm with a maximum at 390 nm and emission intensity at 350 nm. This compound exhibits fungitoxicity against Penicillium notatum and Aspergillus fumigatus.</p>

<p>2-Chloro-3-(hydroxymethyl)pyridine is an organic compound that is used as a building block for the synthesis of other heterocycles. This compound can be synthesized from 2-chloronicotinic acid, which is obtained by oxidation of nicotine with sodium hypochlorite in the presence of potassium ion. The reaction proceeds via a cleavage of the C-Cl bond and formation of a pyridine ring. The catalytic process can be performed at room temperature and at atmospheric pressure in a variety of solvents, including water.<br>2-Chloro-3-(hydroxymethyl)pyridine has been shown to have high yields for the preparation of compounds such as 2,4-dichloropyridine and 4,5-dichloropyrimidine. It also has been used in the preparation of pharmaceuticals such as atrial natriuretic factor (ANF).</p>

<p>Please enquire for more information about 6-Chloro-pyridazine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>