Amines

<p>Applications 2-(3-Aminopropylamino)ethanol is the hydroxy analogue of WR-1065 (A576820), a metabolite of Amifostine (A576810). Amifostine is an organic thiophosphate that has the ability to protect a broad range of tissues from cytotoxicity (e.g. from chemotherapeutic agents) without inducing an antitumour response. 2-(3-Aminopropylamino)ethanol is also used as an nucleophilic tag in the detection of human butyrylcholinesterase adducts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Antonadou, D., et al.: Int. J. Rad. Oncol. Biol. Phys., 52, 739 (2002); Kemp, G., et al.: J. Clin. Oncol., 14, 2101 (1996)<br></p>

<p>Applications (1R)-2,3-Dihydro-N-2-propen-1-yl-1H-inden-1-amine Ethanedioate is an intermediate used in the synthesis of propargylated aminoindan derivatives via allylation, bromination, dehalogenation sequence.<br>References Phull, M., et al.: PCT Int. Appl., WO 2009081148 A1 20090702 (2009)<br></p>

<p>Applications 5-Amino-2-bromobenzoic acid (cas# 2840-02-0) is a useful research chemical.<br></p>

<p>Applications Benzyltrimethylammonium dichloroiodate is used in the mechanism of oxidation.<br>References Srinivasan, N., et al.: Tetrahedron, 30, 419 (1974), Sankhla, R., et al.: J. Chem. Res., 0465 (2002),<br></p>

<p>Applications (S)-2-Amino-3-(4-aminophenyl)propan-1-ol is derived from (2S)-2-Amino-3-(4-nitrophenyl)-1-propanol (A618365), which can be used as an intermediate in the synthesis of various pharmaceutical compounds. It is used in the preparation of a new series of 2-substituted thiazole carboxamides as potent inhibitors of Akt kinases.<br>References Shaohua, Ch., et al.: Bioorg. Med. Chem. Lett., 22, 1208 (2012);<br></p>

<p>Applications 3-(1-(Ethylamino)cyclohexyl)phenol is a useful synthesis intermediate.<br></p>

<p>Applications 5-Amino-1,2,3-thiadiazole, as a thiadiazole derivative, is a privileged structure in medicinal chemistry and has been investigated for anticonvulsant and antimicrobial activities.<br>References Matsumoto, T., et al.: Masakuni; PCT Int. Appl. (2006), WO 2006054652 A1 20060526; Gommaa, A., et al.: Alexandria J. Pharm. Sci., 5, 153 (1991)<br></p>

<p>Applications Ethyl trans-2-(4-aminocyclohexyl)acetate, HCl<br></p>

<p>Applications 6-​Amino-​5-​nitrochromen-​2-​one is a reagent used in the synthesis of pyranopyridinediones.<br>References Khan, M. et al.: J. Pure App. Sci., 22, 37 (2004);<br></p>

<p>Applications O-((Perfluorophenyl)methyl)hydroxylamine Hydrochloride functions as one of the substances used in the identification of stable cytotoxic factors in extracts of cigarette smoke and in the pharmacological characterization of their cytotoxicity.<br>References Noya Y., et al.: Toxicology, 314, 1 (2013)<br></p>

<p>Applications (±)-trans-1,2-Diaminocyclohexane is a reagent used in the thyroid receptor agonists for treatment of androgenetic alopecia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Li, J. J., et al.: Bioorg. Med. Chem. Lett., 20, 306 (2010)<br></p>

<p>Applications hexyl 4-aminobenzoate (cas# 13476-55-6) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications Aminophenethylamine is an efficient sorbent for the separation of dopamine.<br>References Lulinski, P., et al.: Talanta, 119, 623 (2014)<br></p>

<p>Stability Hygroscopic<br>Applications 1-Amino-3-Hydroxybenzene is used in the preparation of inhibitors of mammalian carbonic anhydrase isoforms. Also used in the preparation of quinoline tethered fluorescent carbon dots for regulated anticancer discovery.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carta, F. et al.: Bioorg. Med. Chem., 21, 1564 (2013); Karthik, S. et al.: Chem. Comm., 49, 10471 (2013);<br></p>

<p>Applications Intermediate in the preparation of Trimebutine metabolites.<br></p>

<p>Applications 1,2,4-oxadiazol-3-amine (cas# 39512-64-6) is a useful research chemical.<br></p>

<p>Applications Tetra-N-octylammonium iodide (CAS# 16829-91-7) is a tetraalkylammonium salt and a useful nitrogen-containing building block. Tetra-N-octylammonium iodide is also used as a solid extrantant for platinum and gold in analysis of natural objects.<br>References Dmitriev, S.; et al.: Anal. Sci., 7, 65 (1991).<br></p>

<p>Applications 3-Amino-4-hydroxybenzoic acid (cas# 1571-72-8) is a useful research chemical.<br></p>

<p>Applications N-Benzylethylenediamine can be used to develop imidazoline derivatives as ligands for dopamine D4 receptor. It is also a reagent for enantioselective synthesis of epoxides and piperazinones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mammoli, V., et al.: ChemMedChem 11, 1819 (2016); Meninno, S., et al.: Org. Lett. 17, 4348 (2015)<br></p>

<p>Stability Volatile<br>Applications rac 1,2-Diaminopropane is used as model precursor in the electron induced deposition of amorphous carbon nitride films. It is also used to synthesize cage peroxide, 1,6-diaza-3,4,8,9-tetraoxa-11-methylbicyclo[4.4.2]dodecane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wnuk, J., et al.: J. Phys. Chem., 113, 12345 (2009); Edward, J., et al.: Can. J. Chem., 77, 1057 (1999)<br></p>

<p>Applications 4'-Dimethylaminophenyl acetylene<br></p>

<p>Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.<br></p>

<p>Applications O-Benzylmetaraminol is an impurity of M225565.<br></p>

<p>Applications 4-(Aminomethyl)-Cyclohexanecarboxylic Acid (cas# 701-54-2) is a useful research chemical.<br></p>

<p>Applications Ecamsule Triethanolamine is used in the preparation of sunscreens providing a UV filter.<br>References Salvador, A. et al.: Anal. Achim. Acta., 537, 15 (2005);<br></p>

<p>Applications N-Hydroxybenzylamine Hydrochloride, is a versatile intermediate for the synthesis of various pharmaceutical compounds. It is used for the preparation of Ticagrelor (T437700) derivatives as novel antiplatelet agents.<br>References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007);<br></p>

<p>Applications Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Akesson B. et al.: Int Arch Occup Environ Health. 1986;57(4):297-302. 2. Roos RW. et al.: J Chromatogr. 1986 Dec 24;370(3):403-18.<br></p>

<p>Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.<br>References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)<br></p>

<p>Applications 6-Amino-5-nitrouracil (cas# 3346-22-3) is a compound useful in organic synthesis.<br>References Graves, A., et al.: J. Mol. Biol., 377, 914 (2008),<br></p>

<p>Applications cyclopent-2-en-1-amine hydrochloride (cas# 91469-54-4) is a useful research chemical.<br></p>

<p>Applications 4-(4-Aminophenoxy)benzonitrile<br></p>

<p>Applications 3-(Cyclopropylaminocarbonyl)phenylboronic acid<br></p>

<p>Applications 2,2-Diethoxy-N-ethylethanamine is used in the preparation of 1-substituted-2-mercaptoimidazoles with antithyroid activity.<br>References Jones, R.G.J. Am. Chem. Soc., 71, 4000 (1949)<br></p>

<p>Applications 2-Amino-2-cyclopropylpropanenitrile, is an enamine building block that can be used in the synthesis of various chemical compounds, such as in synthesis of 5-substituted hydantoins, and Ketone-Derived Enamides.<br>References Murray, R. G. et al.: Organic &amp; Biomolecular Chemistry, Vol: 6, P: 988-99 1 (2008); Coussanes, G. et al.: euro. J. Org. Chem, Vol 2016, P: 4176-4188 (2016);<br></p>

<p>Applications A caged, photolabile Nitric Oxide donor that is useful for delivering nitric oxide into intracellular compartments in microsecond time scale without any cytotoxic effects.<br>References Namiki, S., et al.: Bioorg. Med. Chem., 7, 1695 (1999),<br></p>

<p>Applications 4,4'-Dimethoxydiphenylamine is a diphenylamine derivative used as a chemical additive for cured rubber. 4,4'-Dimethoxydiphenylamine is highly toxic and may potentially induce chromosome abberation.<br>References Kel'man, G.Y. et al.: Kauch. Rez., 26, 28 (1967); Sofuni, T. et al.: Mutat. res. Gen. Toxicol. Test., 24, 175 (1990);<br></p>

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications Used in the preparation of (R)-Sulforaphane (S699105).<br></p>

<p>Applications A polyethyleneglycol (PEG) derivative used in the preparation of single cell optical biosensors.<br>References Kilian, K. et al.: Nano Lett., 9, 2021 (2009); Kilian, K. et al.: Proc. SPIE, 7397, 739703 (2009);<br></p>

<p>Applications n-Dipropylamine is a useful reagent for the preparation of perylene derivatives for photosensitive fluorescent resins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jang, H., et al.: PCT Int. Appl. (2021), WO 2021010703 A1<br></p>

<p>Applications N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide (cas# 10558-45-9) is a useful research chemical.<br></p>

<p>Applications 2-Benzylthio-5-amino-1,3,4-thiadiazole is used to study and investigate its antitumor activities against human cervix adenocarcinoma(HeLa), human liver cancer cell(SMMC-7721), human breast cancer cell(MCF-7) and human lung cancer cell(A549) lines that isfurther evaluated by CCK-8 assay.<br>References Zhao, J., et. al., Chem. Res. Chin. Univ.,30, 764-769 (2014)<br></p>

<p>Applications N10-(Ethoxycarbonyl)tryptamine is an intermediate in the synthesis of N-Methyltryptamine-d3 (M331922), which is a labeled N-Methyltryptamine, a N-monomethylated derivative of tryptamine. N-Methyltryptamine, unlike its unmethylated counterpart, does not produce any psychoactive effects. High levels of N-Methyltryptamine have been found in cisternal cerebrospinal fluid of patients with acute paranoid schizophrenia.<br>References Schmid, C. et al.: J. Neurosci., 30, 13513 (2010); Uebelhack, R. et al.: Biomed. Biochim. Acta, 42, 1343 (1983);<br></p>

<p>Applications 3-​[[[3-​(Aminomethyl)​-​5-​methyl-​1-​oxohexyl]​amino]​methyl]​-​5-​methyl-hexanoic Acid is an intermediate in synthesizing 4,9-Diisobutyl-1,6-diazecane-2,7-dione (D456300), an impurity of rac-Pregabalin (P704800) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>

<p>Applications 5-Iodo-2-aminoindane<br></p>

<p>Applications 4,4-Diethoxy-N,N-diethyl-1-butanamine is a useful reagent for the synthesis of amino acetals.<br>References Keglevic, D., et al.: Croat. Chem. Acta, 35, 175(1963)<br></p>

<p>Applications (3,3-diethoxypropyl)dimethylamine (cas# 16851-30-2) is a useful research chemical.<br>References Choi, G., et al.:Angew. Chem. Int. Ed., 57,6166(2018)<br></p>

<p>Applications Tetrabutylammonium tetrafluoroborate (cas# 429-42-5) is a useful research chemical.<br></p>

<p>Applications 5-(Aminomethyl)-2,3-dihydro-1H-inden-1-one Hydrochloride is a useful research chemical for organic synthesis.<br></p>

<p>Applications N-Benzoylcarbonylaminoacetamidine Hydrochloride (cas# 50850-19-6) is a compound useful in organic synthesis.<br>References Kitagawa, H., et al.: Bioorg. Med. Chem. Lett., 17, 4982 (2007),<br></p>

<p>Applications 1,10-Diaminodecane (cas# 646-25-3) is a useful research chemical.<br></p>

<p>Applications Tetramethylammonium Bromide (cas# 64-20-0) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aslan, K., et al.: J. Fluoresc., 14, 391 (2004), Gole, A., et al.: Langmuir, 20, 7117 (2004), Cavalcante, A., et al.: Biochem. Eng. J., 29, 258 (2006),<br></p>

<p>Applications 2-(4-Amino-2-ethoxyphenyl)pthalimide (cas# 106981-52-6) is a compound useful in organic synthesis.<br></p>

<p>Applications ethyl 3-amino-3-oxopropanoate (cas# 7597-56-0) is a useful research chemical.<br></p>

<p>Applications (2S)-2-acetamido-5-(diaminomethylideneamino)pentanoic Acid (cas# 155-84-0) is a useful research chemical.<br></p>