Amines

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications 6-AMINO-2,2-DIMETHYL-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE (cas# 105807-84-9) is a useful research chemical.<br></p>

<p>Applications 2-Aminobenzylcyanide is a useful reagent for organic synthesis and other chemical processes. It is used in the synthesis of triazolopyridines as a selective JAK1 inhibitors.<br>References Menet, C. J., et al.: J. Med. Chem., 57, 9323 (2014)<br></p>

<p>Applications 2-Aminopropane-1,3-diol is used in the synthesis of novel potent inhibitors of human uridine phosphorylase used to reduce toxicity of 5-fluorouracil without affecting its antitumor activity.<br>References Renck, D. et al.: J. Med. Chem., 56, 8892 (2013);<br></p>

<p>Applications 2-(4-Aminophenyl)propanoic acid is a reagent in the preparation of 3-aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents (Erratum).<br>References Pevarello, P., et al.: J. Med. Chem., 48, 5058 (2005);<br></p>

<p>Applications N-(3-Aminopropyl)acetamide Hydrochloride salt is a salt form of N-Acetyl-1,3-propanediamine (A165390), which is an protected intermediate in the synthesis of analogs of Spermidine (S680400), an antineoplastic agent.<br>References Bergeron, R. et al.: J. Med. Chem, 40, 1475 (1997);<br></p>

<p>Applications 5-Amino-2-chloro-4-fluorophenol is a reagent involved in the design and structure of potent vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitors.<br>References Hennequin, L. F., et al.: J. Med. Chem., 42, 5369-5389 (1999);<br></p>

<p>Applications Oleylamine is a surfactant in the synthesis of nanoparticles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N-(4-Bromophenyl)-[1,1-biphenyl]-4-amine is a useful reagent for preparing carbazole and dibenzofuran-linked tertiary arylamine compounds, which may improve electroluminescent properties.<br>References Ito, H., et al.: Jpn. Kokai Tokkyo Koho (2020), JP 2020093979 A<br></p>

<p>Applications Mevinolinic Acid, Monoammonium Salt can be used as reactant/reagent in process for the preparation of the Simvastatin precursor, 2,2-dimethylbutanoic acid (1S,3R,7S,8S,8aR)-8-[(3R,5R)-7-(cyclopropylamino)-3,5-dihydroxy-7-oxoheptyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, via an amidation reaction.<br>References Khanna, J., et al.: Indian, IN 184809 A1 20000930 (2000)<br></p>

<p>Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.<br></p>

<p>Applications 4-Amino-2-isopropylphenol is a building block used in the preparation of benzoate and benzamide derivatives as FXR antagonists.<br>References Song, K., et al.: Bioorg. Med. Chem., 23, 6427 (2015);<br></p>

<p>Applications 2-Amino cyclopentanol<br></p>

<p>Applications Methyl 2-Aminothioazole-4-carboxylate (cas# 118452-04-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-(2-Aminoethoxy)propionic Acid (cas# 144942-89-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Chloropyridazin-3-amine is an intermediate used to prepare aminopyrazines as novel, potent Nav1.7 antagonists.<br>References Bregman, H., et al.: Bioorg. Med. Chem. Lett., 22, 2033 (2012)<br></p>

<p>Applications 1-(9H-Purin-6-ylamino)propan-2-ol is a reagent used for organic synthesis and also functions as a plant growth regulator.<br>References Gao, Y., et al.: J. Heterocyclic Chem., 53, 579 (2016); Oda, A., et al.: From Faming Zhuanli Shenqing (2016), CN 105503875 A 20160420; Lira, E. P.: J. Org. Chem., 33, 3355 (1968)<br></p>

<p>Applications 4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-butanamine is a reactant that is used for the synthesis of various racemic and biotinylation of azamacrocycles.<br>References Krivickas, S.J., et al.: J. Org. Chem. 72, 8280 (2007).<br></p>

<p>Applications 5-PHENYL-1,2,4-TRIAZIN-3-AMINE (cas# 942-60-9) is a useful research chemical.<br></p>

<p>Applications N,5-diphenyl-1,3,4-thiadiazol-2-amine (cas# 1437-57-6) is a useful research chemical.<br></p>

<p>Applications N-[[4-(Phenylmethoxy)phenyl]methyl]-2-[(3-thienylcarbonyl)amino]-4-thiazoleacetamide is derived from ethyl 2-amino-4-thiaxolacetate (E899330) which is used in the synthesis of various pharmaceutical and biologically active compounds including inhibitors and antibiotics.<br>References Inamoto, Y., et al.: J. Antibiot., 41, 828 (1988)<br></p>

<p>Applications 4-Azidobutylamine is weakly or non-mutagenic to Salmonella typhimurium.<br>References Owais, W.M., et. al.: Mutat. Res. Genetic Toxicol. Testing, 118, 229 (1983)<br></p>

<p>Applications 1-Decylamine is an intermediate forming the phosphatidylcholine-decylamine liposomal membranes.<br>References Kotynska, J., et al.: J. Bioenerget. Biomembrane., 40, 637 (2008);<br></p>

<p>Applications Used in the preparation of pyrimidine derivatives.<br></p>

<p>Applications 9-(2-(Benzyloxy)ethyl)-2-((2-(benzyloxy)ethyl)amino)-1H-purin-6-(9H)-one is an intermediate used in the synthesis of 9-(2-Hydroxyethyl)guanine (H942035), which is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.<br>References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);<br></p>

<p>Applications Methyl 4-(Methylamino)picolinate is a pyridinyl building block and a useful synthetic intermediate.<br></p>

<p>Applications 4-(Methylamino)-3-nitrobenzoic Acid (cas# 41263-74-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Ammonium Carbonate Carbamate is used in the study of amino acids and has important implications in biochemical studies.<br>References Nanping, W. et al.: J. Phys. Chem., 99, 359 (1995);<br></p>

<p>Applications Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br></p>

<p>Applications 2,4-Diaminobenzenesulfonic acid (cas# 88-63-1) is a useful reagent for improving the chlorine resistance and water permeability of polyamide (PA) membrane in water treatment.<br>References Meng, Q. W., et al.: ACS Applied Mat., 12, 35393 (2020)<br></p>

<p>Applications Ethyl 3-Aminocrotonate is used as a reagent to synthesize Nitrendipine (N490150), a calcium channel antagonist that is used to treat patients with hypertension. Ethyl 3-Aminocrotonate is also used as a reagent to synthesize (S)-Felodipine (F232370), a calcium entry blocker that has antihypertensive properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bailey, D., et al.: Clin. Invest. Med., 12, 357 (1989); Bean, B.: Proc. Nat. Acad. Sci., 81, 6388 (1984); Kwon, K., et al.: Tetrahedron, 67, 10222 (2011); Leenen, F. &amp; Holiwell, D.: Am. J. Cardio., 69, 639 (1992); Meyer, H., et al.: Arz. Forsch., 33, 1528 (1983); Stoepel, K., et al.: Arz. Forsch., 31, 2056 (1980)<br></p>

<p>Applications Tetrabutylammonium Dibromochloride (cas# 64531-21-1) is a useful research chemical.<br></p>

<p>Applications 5-Aminoboronphthalide is used as a reactant in the preparation of 2,1-benzoxaborole peptide isoquinoline derivatives as HCV NS3 protease inhibitors. It is also used as reactant in the synthesis of nanocarrier for chemomechanically driven guest delivery fueled by intracellular ATP.<br>References Li, X., et al.: Bioorg. Med. Chem. Lett., 21, 2048 (2011); Biswas, S., et al.: Nat. Chem., 5, 613 (2013);<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 4-(2-Aminophenyl)-4-oxo-2-butenoic Acid is a novel human lens metabolite from normal and cataractous human lenses. A UV filter.<br>References Mizdrak, J., et al.: Tetrahedron, 63, 4990 (2007); Taylor, L. M., et al.: Exp. Eye Res., 75, 165 (2002)<br></p>

<p>Applications Used in the preparation of homobifunctional rhodamine for labeling proteins.<br>References Corrie, J. et al.; Bioconjugate Chem. 9, 160 (1998)<br></p>

<p>Applications Trimethylphenylammonium Iodide (cas# 98-04-4) is a compound useful in organic synthesis.<br>References Dorweiler, J., et al.: Biochem., 42, 14653 (2003),<br></p>

<p>Stability Moisture Sensitive<br>Applications 3-[(2-hydroxyethyl)amino]propanenitrile (cas# 33759-44-3) is a useful research chemical.<br></p>

<p>Applications 1-(2-Phenylethynyl)cyclohexanamine is a reactant that functions as a catalyst in the cyclization of propargylamines.<br>References Zhao, D. et al.: ChemCatChem., 9, 4598 (2017); Yuan, R. et al.: J. Org. Chem., 82, 3639 (2017);<br></p>

<p>Applications Isopropyl 3-Aminocrotonate (cas# 14205-46-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Dimethylamine (40% aq.) is a compound often used in industry as a precursor to Nitrosodimethylamine (N525625), a potent carcinogen that is produced during disinfection of wastewater effluent, and is also present in trace amounts in food and polluted air. Dimethylamine is also present in human urine and can be indicative of certain disorders.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gereke, A. &amp; Sedlak, D.: Env. Sci. Tech., 37, 1331 (2003); Mitch, W., et al.: Env. Eng. Sci., 20, 389 (2003); Tsikas, D., et al.: J. Chromatogr. B, 851, 229 (2007)<br></p>

<p>Applications 3-(1-(Ethylamino)cyclohexyl)phenol is a useful synthesis intermediate.<br></p>

<p>Applications 3-(3-Butyn-1-yl)-3H-diazirine-3-ethanamine can be used as reactant/reagent in minimalist cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling.<br>References Li, Z., et al.: J Am Chem Soc, 136, 9990 (2014)<br></p>

<p>Applications (1R)-2-(methylamino)-1-phenylethan-1-ol (cas# 495-42-1) is a useful research chemical.<br></p>

<p>Applications N-[(2,4-Difluorophenyl)methylene]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D450850), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.<br>References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)<br></p>

<p>Applications 2-Amino-5-formylthiazole is a useful reagent for the preparation of cationic azo dyes.<br>References Salvador, M. A., et al.: Dyes and Pigments, 82, 118 (2009); Salvador, M. A., et al.: Tetrahedron, 64, 299 (2008)<br></p>

<p>Applications Cyclopent-3-enamine hydrochloride (cas# 91469-55-5) is a useful research chemical.<br></p>

<p>Applications [4-[3-[[(Methylamino)methylene]amino]phenyl]-2-thiazolyl] Guanidine is a guanidino heterocyclic phenylamidines with pharmaceutical properties.<br>References Bietti, G., et al.: Eur. Pat. Appl. (1983), EP 89730 A2 19830928<br></p>

<p>Applications DL-3-aminoisobutyric acid hydrate is a useful research chemical for organic synthesis and other chemical processes.<br>References Saito, N., et al.: Bunseki Kagaku, 63, 909 (2014)<br></p>

<p>Applications 4-Amino-1,3-benzenedisulfonic Acid is used as a reagent in the synthesis of arylazopyridoxal phosphate and phosphonate derivatives as P2 receptor antagonists.<br>References Kim, Y., et al.: Drug Develop. Res., 45, 52 (1998)<br></p>

<p>Applications An intermediate of Synergistin. Antibacterial.<br></p>

<p>Applications Ethyl trans-2-(4-aminocyclohexyl)acetate, HCl<br></p>

<p>Applications O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine can be used to treat fibrotic and inflammatory diseases.<br>References Gomer, R.H., et.al., PCT Int. Appl., 167, (2020);<br></p>

<p>Applications Ammonium Hydroxide is in numerous household cleaning agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lokshin, E.P., et al.: Russ. J. App. Chem., 86, 450 (2013); Alghamdi, A.A., et al.: J. Material. Chem. A. Mater. Energy. Sustain., 1, 5165 (2013);<br></p>

<p>Applications 4-(3-aminopropyl)-N,N-dimethylaniline (cas# 112103-97-6) is a useful research chemical.<br></p>

<p>Applications 4-(4-Aminophenoxy)benzonitrile<br></p>

<p>Applications N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide (cas# 10558-45-9) is a useful research chemical.<br></p>

<p>Applications 5-(Aminomethyl)furan-2-carboxylic Acid Hydrochloride is a useful reagent in the preparation of novel heteroaromatic substrates of GABA aminotransferase.<br>References Hawker, D. D., et al.: Bioorg. Med. Chem., 20, 5763 (2012)<br></p>

<p>Applications TERT-BUTYL N-(DIAMINOMETHYLIDENE)CARBAMATE (cas# 219511-71-4) is a useful research chemical.<br></p>

<p>Applications Di-[2-(2,3-dichlorophenyl)aminoethyl]amine is prepared from 1-Bromo-2,3-dichlorobenzene(B687435) and Diethylenetriamine (D444255). 1-Bromo-2,3-dichlorobenzene is a reagent used in the preparation of selective nonpeptidic inhibitors of striatal-enriched protein tryosine phosphatase.<br>References Baguley, T.D., et al.: J. Med. Chem., 56, 7636 (2013)<br></p>