Amines

<p>Applications 1-(2-Phenylethynyl)cyclohexanamine is a reactant that functions as a catalyst in the cyclization of propargylamines.<br>References Zhao, D. et al.: ChemCatChem., 9, 4598 (2017); Yuan, R. et al.: J. Org. Chem., 82, 3639 (2017);<br></p>

<p>Applications O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine can be used to treat fibrotic and inflammatory diseases.<br>References Gomer, R.H., et.al., PCT Int. Appl., 167, (2020);<br></p>

<p>Applications (1R)-2,3-Dihydro-N-2-propen-1-yl-1H-inden-1-amine Ethanedioate is an intermediate used in the synthesis of propargylated aminoindan derivatives via allylation, bromination, dehalogenation sequence.<br>References Phull, M., et al.: PCT Int. Appl., WO 2009081148 A1 20090702 (2009)<br></p>

<p>Applications Used for the preparation of dihydrouracils as anti-ictogenic or anti-epileptogenic agents.<br>References Akoulitchev, S., et al.: Nature, 377, 557 (1995), Marshall, N., et al.: J. Biol. Chem., 270, 12335 (1995), Marshall, N., et al.: J. Biol. Chem., 271, 27176 (1996), Shapiro, G., et al.: J. Clin. Oncol., 24, 1770 (2006),<br></p>

<p>Applications 5-Amino-2-bromobenzoic acid (cas# 2840-02-0) is a useful research chemical.<br></p>

<p>Applications Benzyltrimethylammonium dichloroiodate is used in the mechanism of oxidation.<br>References Srinivasan, N., et al.: Tetrahedron, 30, 419 (1974), Sankhla, R., et al.: J. Chem. Res., 0465 (2002),<br></p>

<p>Stability Hygroscopic<br>Applications 2-(2,5-diaminophenyl)ethanol Sulfate (cas# 93841-25-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-[2-(2-azidoethoxy)ethoxy]ethanamine (cas# 166388-57-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Aminohydantoic Acid is an intermediate in the synthesis of new derivative of 5-Nitro-2-furfural, proved to be bactericidal.<br>References Swirska, A., et al.: Rocz. Chem., 31, 1335 (1957);<br></p>

<p>Applications Ethyl trans-2-(4-aminocyclohexyl)acetate, HCl<br></p>

<p>Applications Aminoacetonitrile is a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.<br>References Ward, Y., et al.: J. Med. Chem., 45, 5471 (2002); Wilkerson, W., et al.: J. Med. Chem., 40, 4079 (1997)<br></p>

<p>Applications hexyl 4-aminobenzoate (cas# 13476-55-6) is a useful research chemical.<br></p>

<p>Applications N-Ethyl-3-phenylpropylamine is an intermediate in the synthesis of 4-Hydroxy Alverine (H827950), a metabolite of Alverine (A575780) in plasma.<br>References Bouvier, M., et al.: Gastroenterol. Clin. Biol., 16, 334 (1992), Mitchell, S., et al.: Aliment. Pharmacol. Ther., 16, 1187 (2002), Hayase, M., et al.: Br. J. Pharmacol., 152, 1228 (2007),<br></p>

<p>Applications 9,10-Dihydroergotamine N-Oxide is a useful synthetic compound.<br></p>

<p>Applications 4-(dimethylamino)benzenesulfonamide (cas# 6162-21-6) is a useful research chemical.<br></p>

<p>Applications Ethyl 2-Dimethylaminomethylene-3-oxobutanoate (cas# 51145-57-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Nonoxidative coloring agent for semipermanent coloring of keratin fibers such as hair and wool.<br>References Chen, C., et al.: Science, 279, 851 (1998), Nitz, M., et al.: Chembiochem., 4, 272 (2003),<br></p>

<p>Applications (2S)-2-acetamido-5-(diaminomethylideneamino)pentanoic Acid (cas# 155-84-0) is a useful research chemical.<br></p>

<p>Applications Tetra-N-octylammonium iodide (CAS# 16829-91-7) is a tetraalkylammonium salt and a useful nitrogen-containing building block. Tetra-N-octylammonium iodide is also used as a solid extrantant for platinum and gold in analysis of natural objects.<br>References Dmitriev, S.; et al.: Anal. Sci., 7, 65 (1991).<br></p>

<p>Applications 3-Amino-4-hydroxybenzoic acid (cas# 1571-72-8) is a useful research chemical.<br></p>

<p>Applications Isopropyl 3-Aminocrotonate (cas# 14205-46-0) is a compound useful in organic synthesis.<br></p>

<p>Applications ethyl 3-amino-3-oxopropanoate (cas# 7597-56-0) is a useful research chemical.<br></p>

<p>Applications N-Benzylethylenediamine can be used to develop imidazoline derivatives as ligands for dopamine D4 receptor. It is also a reagent for enantioselective synthesis of epoxides and piperazinones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mammoli, V., et al.: ChemMedChem 11, 1819 (2016); Meninno, S., et al.: Org. Lett. 17, 4348 (2015)<br></p>

<p>Stability Volatile<br>Applications rac 1,2-Diaminopropane is used as model precursor in the electron induced deposition of amorphous carbon nitride films. It is also used to synthesize cage peroxide, 1,6-diaza-3,4,8,9-tetraoxa-11-methylbicyclo[4.4.2]dodecane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wnuk, J., et al.: J. Phys. Chem., 113, 12345 (2009); Edward, J., et al.: Can. J. Chem., 77, 1057 (1999)<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 4-(2-Aminophenyl)-4-oxo-2-butenoic Acid is a novel human lens metabolite from normal and cataractous human lenses. A UV filter.<br>References Mizdrak, J., et al.: Tetrahedron, 63, 4990 (2007); Taylor, L. M., et al.: Exp. Eye Res., 75, 165 (2002)<br></p>

<p>Applications 2,4-Diaminobenzenesulfonic acid (cas# 88-63-1) is a useful reagent for improving the chlorine resistance and water permeability of polyamide (PA) membrane in water treatment.<br>References Meng, Q. W., et al.: ACS Applied Mat., 12, 35393 (2020)<br></p>

<p>Applications 4-Azidobutylamine is weakly or non-mutagenic to Salmonella typhimurium.<br>References Owais, W.M., et. al.: Mutat. Res. Genetic Toxicol. Testing, 118, 229 (1983)<br></p>

<p>Stability Hygroscopic<br>Applications N-Benzyl-bis(2-chloroethyl)amine hydrochloride (cas# 10429-82-0) is a useful research chemical.<br></p>

<p>Applications 5-Chloropyridazin-3-amine is an intermediate used to prepare aminopyrazines as novel, potent Nav1.7 antagonists.<br>References Bregman, H., et al.: Bioorg. Med. Chem. Lett., 22, 2033 (2012)<br></p>

<p>Applications 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanethiol is used in the preparation of fluorescent N/S acyl derivatives.<br>References 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)thio]ethanamine<br></p>

<p>Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.<br></p>

<p>Applications 2-(4-Aminophenyl)propanoic acid is a reagent in the preparation of 3-aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents (Erratum).<br>References Pevarello, P., et al.: J. Med. Chem., 48, 5058 (2005);<br></p>

<p>Applications (S)-Pyroglutaminol (cas# 17342-08-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Nitro-1,3-diaminobenzene is a general chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of potent and selective Chk-1 inhibitors in the treatment of various cancers.<br>References Wang, L. et al.: J. Med. Chem., 50, 4162 (2007);<br></p>

<p>Applications 5-Iodo-2-aminoindane<br></p>

<p>Racemic amphetamine is a psychoactive substance that has been extensively used in the past as a stimulant, for example in the treatment of ADHD and narcolepsy. Racemic amphetamine is typically used to monitor drug use or to identify adulterants in urine samples. It is also used in the analysis of psychoactive substances and for the detection of phenylpropanolamine (PPA) and formic acid. Racemic amphetamine is a controlled substance that can be found in various forms, including methanolic solution, dilution, analyze, and reaction monitoring. Its use has been shown to be linear and it can be quantified by high-performance liquid chromatography.</p>

<p>Please enquire for more information about 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Amino-3,5-difluorobenzonitrile is a fine chemical used as a building block in research chemicals, reagent, and speciality chemical. It is versatile and can be used as a reaction component in the synthesis of complex compounds with various applications. CAS No. 110301-23-0 is an important intermediate for the synthesis of organic compounds and pharmaceuticals. 4-Amino-3,5-difluorobenzonitrile is also used as a scaffold for the synthesis of organic compounds.</p>

<p>Please enquire for more information about 2-(4-fluorophenyl)-n-methylethanamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Amino-5-bromopyridine (3ABP) is a linker for the synthesis of cisplatin. It has been shown to have strong bactericidal activity against Escherichia coli and Staphylococcus aureus. 3ABP is cytotoxic to both renal proximal tubule cells and ring-opening cells, which are found in the kidney. It is also an inhibitor of nicotinic acetylcholine receptors (nAChRs), which are proteins that control nerve cell communication. 3ABP's pharmacokinetic properties make it suitable as a linker for cisplatin, as it has good oral bioavailability, low systemic toxicity, and high tissue selectivity.</p>

<p>N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine hydrochloride (NMBPD) is a drug with anti-inflammatory properties that belongs to the class of tricyclic antidepressants. It has been shown to have synergistic effects with synthetic matrix in vitro. This drug also has receptor activity and can be used to treat infectious diseases such as HIV and tuberculosis. NMBPD is excreted in the urine, which can lead to kidney fibrosis. The drug is metabolized by α1-acid glycoprotein, which may be related to its potential adverse effects on the liver and kidneys. The analytical method for quantification of NMBPD includes gas chromatography with mass spectrometry detection (GC/MS).</p>

<p>Please enquire for more information about 1-(Fmoc-amino)-4,9-dioxa-12-dodecanamine·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-(2-Dimethylamino)Ethyl) Pyridine is a chemical compound that contains oxygen atoms, hydroxo, and nitrogen atoms. It has a tetranuclear hexahydrate form and the molecular formula C5H7N3O2. 2-(2-Dimethylamino)Ethyl) Pyridine has been shown to have desilylation properties. 2-(2-Dimethylamino)Ethyl) Pyridine binds to group P2 of RNA and represses translation by preventing ribosomal binding to the mRNA strand. This drug is also an x-ray data collection agent in which it is used as a ligand in magnetic resonance imaging (MRI).</p>

<p>(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide is an amide. It is a hydrochloric acid salt that can regulate the reaction system and introduce filtration, which can be used to separate the components of the reaction system. The kinetic and chiral properties of this compound are derived from Friedel-Crafts reactions with phosphites and Friedel-Crafts reactions with d-alanine. (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide can also catalyze ammonolysis and catalysis with phenoxy.</p>

<p>Please enquire for more information about 4-Amino-1-Boc-piperidine-4-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Dimethylaminopyridinium Bromide Perbromide is a synthetic compound that contains a phenolic hydroxyl group. It reacts with chloride to form the perbromide salt, which is anhydrous and insoluble in water. The compound has been shown to inhibit the growth of cancer cells by interfering with DNA replication and transcription.</p>

<p>Please enquire for more information about 2-(Aminomethyl)-1,3-benzothiazole hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(4'-Methoxy-3'-sulfonamidophenyl)-2-propylamine, hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-alpha-Boc-Ngamma-Azido-L-2,4-diaminobutyric acid cyclohexylamine salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fluvoxamine acid is a serotonin reuptake inhibitor that is used to treat depression. It is metabolized by hydrolysis to the active form, fluvoxamine, which inhibits the re-uptake of serotonin in the presynaptic neuron. Fluvoxamine acid has been shown to be effective for some types of depression and has a low incidence of adverse effects. Fluvoxamine acid binds to human serum albumin (HSA) and plasma proteins such as alpha-1-acid glycoprotein. The drug also has pharmacokinetic properties including an acidic pH, high lipophilicity and low protein binding.</p>

<p>3-Methoxyphenethylamine is a naturally occurring phenethylamine that is found in the human body. It is produced by the enzyme phenylethanolamine N-methyltransferase from dopamine and 3-methoxytyramine. 3-Methoxyphenethylamine can be found in the saliva, but also in the brain, muscle and kidneys. Its presence has been detected in women's breast milk. This compound has been shown to have a significant effect on chloride ion absorption and renal blood flow, as well as on 5-hydroxyindoleacetic acid levels in the urine of patients with Parkinson's disease. The predominant metabolite of 3-methoxyphenethylamine is 3-hydroxymethylphenethylamine (3HMPEA).</p>

<p>Please enquire for more information about Desmethyl chlorpheniramine maleate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alpha-amino-2H-tetrazole-5-acetic acid (AAT) is a neurotoxin that inhibits glutamate receptors and causes neuronal cell death. It also decreases heart function in rats by inhibiting the cardiac sodium channel. AAT has been shown to be effective for inducing neuronal death in Xenopus oocytes, as well as decreasing the expression of certain receptor protein, such as NMDA and AMPA receptor subtypes. AAT is also known to cause apoptosis, which may be due to its inhibition of receptor function.</p>

<p>4-Amino-1,3-dimethyl-2,6-dioxo-5-nitrosopyrimidine is a monoclonal antibody that binds to cancer cells. It has been shown to be effective in the treatment of leukemia, Hodgkin's disease, and non-Hodgkin's lymphoma. The binding of 4-Amino-1,3-dimethyl-2,6-dioxo-5-nitrosopyrimidine to cancer cells is due to the formation of a coordination geometry between the copper complex and the nitrogen atoms on the amino group. This drug has been shown to inhibit tumor growth by blocking the synthesis of DNA and RNA, which are key components in cell division. 4AADNP also inhibits cancer cells' ability to uptake glucose by inhibiting cellular glucose transporters. The binding affinity of 4AADNP for cancer cells is higher than for normal cells because cancer cells have more receptors for this drug</p>

<p>Please enquire for more information about 3-Chloro-N-methylpropan-1-amine HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Intermediate in the synthesis of anagliptin</p>

<p>Please enquire for more information about (1-Methyl-1H-indazol-3-yl)methanamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2S,3S)-5-[2-(Dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one hydrochloride is a racemic mixture of two enantiomers. It is a prodrug that is hydrolyzed to its active form, diltiazem. The drug has been shown to be effective in the treatment of hypertension and angina pectoris. (2S,3S)-5-[2-(Dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one hydrochloride has been shown to inhibit the activity of the enzyme phosphodiesterase which breaks down cyclic AMP. This inhibition results in an increase in levels of</p>

<p>Please enquire for more information about [2-(5-Chloro-1H-indol-3-yl)-1-methylethyl]amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Hydroxy-4-amino-butyric acid is a synthetase that catalyzes the formation of 3-hydroxy-4 amino butyric acid from 3-hydroxy butyric acid and ammonia. This reaction occurs in the presence of chloride ions, ethyl bromoacetate and butyric acid. The isolated yield of this reaction is 47%. The product can be converted to 3-amino butyric acid by dehydrating it with hydrochloric acid. 3-Hydroxy-4 amino butyric acid has been shown to have anticancer properties in vitro. It also has been shown to have antiinflammatory properties, which may be due to its ability to inhibit the production of prostaglandin E2, an inflammatory mediator.</p>

<p>5-Oxo Rosuvastatin is a drug product that has been synthesized from natural ingredients. It is an analytical standard for the impurity, 5-oxo-rosuvastatin, which is a potential impurity in the API, rosuvastatin. This drug product has been custom synthesized in order to provide an Impurity Standard for HPLC. This drug product is also used as a Synthetic Reference Standard for Drug Development and Research and Development.</p>

<p>N-Nitrosodicyclohexylamine (NDCA) is a chemical that is used as a corrosion inhibitor. The stability of NDCA in the environment has been studied extensively and found to be resistant to many conditions including heat, light, and pH. NDCA is absorbed by the skin or ingested and has been shown to cause genotoxic effects in human lymphocytes. The genotoxic potential of NDCA has also been demonstrated in V79 cells. NDCA reacts with amines to form an intermediate that spontaneously decomposes into nitrosamines, which are carcinogenic. This reaction mechanism was confirmed using analytical methods such as gas chromatography-mass spectrometry (GC-MS).</p>

<p>Please enquire for more information about 2-Amino-1-(2,3-dihydro-benzofuran-5-yl)-ethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-Iodo-2,3-dihydro-1H-inden-2-amine hydrochloride hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-{[(1E)-(dimethylamino)methylene]amino}-5-methoxy-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methoxy-N-methylbenzylamine is a synthesized compound that is structurally similar to piperazine. It has been synthesized using the Chloramine T method and has been shown to be active as an amine receptor ligand. This molecule binds to the amine receptor site of the GABAA receptor with high affinity, inhibiting chloride ion flow. The functional groups on this molecule are likely responsible for its binding activity. 4-Methoxy-N-methylbenzylamine may be useful in the treatment of scopolamine-induced amnesia, due to its ability to bind to specific receptors in the brain.</p>

<p>Please enquire for more information about 5-Amino-3,7-dimethylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Boc-trans-1,2-aminocyclohex-4-ene carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cis-4-Methylcyclohexylamine is a cyclic amine that is found in the form of its decarboxylated derivative, 4-methylcyclohexanamine, which is used as an inhibitor for various enzymes. The methyl group on the cyclohexane ring is responsible for the compound's activity. Magnetic resonance spectroscopy has shown that cis-4-Methylcyclohexylamine binds to the active site of carbonyl reductase and inhibits its enzymatic activity, thereby blocking a step in the citric acid cycle. Cis-4-Methylcyclohexylamine has also been shown to have anti-inflammatory effects by inhibiting protein kinase C (PKC) and NFkB activation.</p>

<p>Please enquire for more information about 3-Amino-5-(2,3,4-trimethoxyphenyl)cyclohex-2-en-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>