Amines

<p>Please enquire for more information about Biotinyl-epsilon-aminocaproyl-D-Phe-Pro-Arg-chloromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fmoc-L-alpha-aminobutyric acid is a synthetic amino acid that is used as a linker in solid-phase peptide synthesis. It is also used to synthesize analogs of the serine protease NS3, which are postulated to inhibit hepatitis C virus replication by preventing the release of viral RNA from infected cells. Fmoc-L-alpha-aminobutyric acid has been shown to have anti-viral activity against the influenza virus and HIV.</p>

<p>N-Methyl-1-propanamine is a compound made up of ethylene diamine and activated chlorine. It has been used as a model system to study the biological properties of amines. This compound has been shown to have anti-cancer effects in human serum and is active against inflammation diseases. N-Methyl-1-propanamine is soluble in water, but not in ethanol or acetone. It has a pH optimum at 10 and decomposes at temperatures higher than 120°C. The activation energies for the reactions of this compound with hydrogen bond acceptors, such as alcohols and ethers, are relatively low (around 20 kcal/mol).</p>

<p>4-Bromo-6-methyl-2-pyridinamine is a small molecule that binds to the bromodomain of the human protein BRD4. This binding inhibits the interaction between BRD4 and acetylated lysine residues on histones, thereby inhibiting transcriptional activation. 4-Bromo-6-methyl-2-pyridinamine has been shown to be a potent inhibitor of the activity of BRD4, which may be due to its chemical stability and ability to inhibit protein synthesis. The compound's potency in inhibition assays and its lack of biochemical toxicity make it an attractive lead compound for further study.</p>

<p>1-(3-Aminopropyl)-2-pyrrolidinone is a chemical compound that has been used as a chemotherapeutic treatment for heart disease and polyamine oxidase deficiency. The compound has also been shown to have a direct effect on the synthesis of fatty acids in the body, which may lead to the development of new treatments for diabetes. 1-(3-Aminopropyl)-2-pyrrolidinone can be formulated into conjugates with other molecules, such as chloride ions or fatty acids, in order to target specific cells or tissues. This method of delivery is efficient and has been shown to be able to cross the blood-brain barrier. 1-(3-Aminopropyl)-2-pyrrolidinone is an amino acid derivative that contains an aminoguanidine functional group. Aminoguanidine inhibits polyamine oxidase activity in vitro by reacting with the carbonyl group at position C</p>

<p>Intermediate in the synthesis of mirabegron</p>

<p>L(+)-2,3-Diaminopropionic acid HCl is a chiral modifier that is used in the separation of organic compounds. It has been shown to selectively interact with borate, sulfate, and hydroxyapatite. This interaction changes the physical properties of these substances by modifying their surface charge or adsorption capacity. L(+)-2,3-Diaminopropionic acid HCl has also been shown to be useful in diastereoselective reactions. The technique of elution can be used to isolate specific compounds from mixtures using this compound as a modifier. Hydrogen bonding groups and moieties on the functional group are important factors in the specificity of this interaction.END&gt;&gt;</p>

<p>4-Aminobutyrophenone is a butyrophenone, a nitro compound that is the amine derivative of 4-aminobutyric acid. This product is used as a control agent in pest control and as an intermediate for pharmaceuticals and dyes. It has been used to produce methemoglobin, which is used to treat nitrate poisoning. 4-Aminobutyrophenone undergoes acylation reactions with chloride or sulfoxide groups to form chlorohydrins and thiohydrins respectively. These products are bioisosteres of the carbonyl group, which can be hydrolyzed with acid or alkali to produce carboxylic acids or alcohols respectively. Friedel-Crafts acylation with phenol gives benzoylphenylhydroxylamine, which can be oxidized by hydrogen peroxide to give the corresponding nitro compound.</p>

<p>Fmoc-S-trityl-L-penicillamine is a coordination compound that contains a thiolate and amide group. It has been used as a model system for studying the interaction between proteins and metal ions, with the cyclic structure mimicking the active site of enzymes. The coordination of Fmoc-S-trityl-L-penicillamine to proteins is affected by trypsin, an enzyme that cleaves peptides at carboxyl side chains. Trypsin can also lead to dehydration of Fmoc-S-trityl-L-penicillamine, forming an eliminations product. This compound also reacts with lysine residues in proteins, resulting in an alkene byproduct that can be removed by hydrogenation.</p>

<p>N-1-Z-1,4-diaminobutane·HCl is a monomeric compound that inhibits protein–protein interactions. It is a broad-spectrum inhibitor of protein–protein interactions and has been shown to have the potential for use in cancer treatments. The linkers on the N-1 and Z positions are important for the interaction with the target protein. The heterocycle at position 1 can vary depending on which protein is targeted. This compound has been effective against a number of proteins that interact with each other, including cyclin A/CDK2, cyclin B/CDK2, and actin/myosin II. This analog has been shown to be achievable by linking two molecules together through an amide bond.</p>

<p>2-Amino-6-hydroxybenzothiazole is a chemical compound that has been shown to have chemiluminescence properties. It is produced in vivo by the synthetase enzyme from the amino acid L-phenylalanine and hydroxybenzothiazole. The compound is expressed in basophilic leukemia cells, which are cells that stain with basic dyes. 2-Amino-6-hydroxybenzothiazole can be used as a marker of these cells in vitro. A second order rate constant of 1.5 × 10 M−1 s−1 was determined for this reaction, which is consistent with other reactions of this type. 2-Amino-6-hydroxybenzothiazole has also been shown to be effective at treating cancer and inflammatory bowel disease by enhancing growth factor production and inhibiting cell proliferation.</p>

<p>Ammonium molybdate tetrahydrate (AMT) is a molybdenum compound with the chemical formula (NH4)6Mo7O24·4H2O. It is a yellow crystalline solid that is soluble in water and n-hexane. AMT has been clinically used for the treatment of Wilson's disease, an inherited disorder that causes copper to accumulate in the body. AMT binds to copper ions and prevents them from being absorbed into the bloodstream. The rate of ATP production increases when AMT is added to cells, which may be due to its effect on electron transport or because it inhibits ATPase activity.</p>

<p>Dimethylbenzyl-(3-sulfopropyl)ammonium, inner salt (DMBAPA-IS) is a nutrient solution that contains antimicrobial agents, such as fatty acids and diastolic pressure. DMBAPA-IS is used in the treatment of infectious diseases. It has been shown to be effective against solid tumours and bacterial strains. The structure of DMBAPA-IS is similar to that of dimethylbenzylammonium chloride (DMBAC), which inhibits bacterial growth by binding to the 30S ribosomal subunit, preventing protein synthesis.</p>

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<p>Please enquire for more information about N1-(Pivaloyloxy)methyl-N2-(dimethylamino)methylene 9-deazaguanine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Isopropyl 2-amino-4-hydroxy-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Amino-4-(4-phenoxyphenylethylamino)quinazoline is a potential anticancer drug that has been shown to inhibit the polymerase chain reaction in human osteosarcoma cells. It also inhibits the signaling pathway of nuclear factor-κB (NF-κB), which is involved in cell death and tumorigenesis. 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline has shown significant cytotoxicity against murine hepatoma cells and bowel disease cells, but not against normal tissue. This drug is also an inhibitor of the drug transporter Pgp. 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline has been shown to be effective in experimental models for cancer, AIDS, and other infectious diseases.</p>

<p>TES, also known as N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid, is a buffering agent that is used in protein assays and forms complexes with DNA and copper ions. The optimal pH range of this zwitterionic buffer is 6.8-8.2 and its pKa is 7.4.</p>

<p>EDTA ferric ammonium is a metal complex that is used in the manufacture of textile dyes. EDTA ferric ammonium is an oxidizing agent that can be used as a reducing agent by adding an oxidizing agent such as potassium permanganate. The solution form of this compound has a particle size distribution with a median particle size of about 0.5 micrometers and a polydispersity index of about 2. In addition, it has been shown to have surfactant properties, which may be due to its ability to interact with the surface tension of water molecules. EDTA ferric ammonium has also been shown to react with silver ions to form silver ethylene diamine tetraacetic acid (AgEDTA), which can then be used for patterning purposes in textiles.</p>

<p>Please enquire for more information about 4-Amino-6-mercaptopyrazolo[3,4-d]pyrimidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Undecafluorohexanoic acid is a perfluoroalkyl carboxylic acid that has been shown to disrupt steroidogenesis in vitro. It may be able to inhibit the transport of cholesterol, fats, and other lipids in cells, which causes disruption in steroidogenesis. This compound also has anti-cancer properties due to its ability to induce apoptosis and arrest cancer cell proliferation. Undecafluorohexanoic acid may also have developmental effects on animals because it can bind to estrogen receptors and disrupt the normal process of estrogen-mediated signaling pathways.</p>

<p>Boc-4-aminopiperidine is a molecule that is used as a substrate in chemical reactions. It reacts with sodium hydroxide solution to form an imine, which is hydrogenated by reducing agents such as NaBH4. This reaction yields the products 4-aminopiperidine and acetaldehyde. Boc-4-aminopiperidine is also utilized as a cholinesterase inhibitor, which inhibits the breakdown of acetylcholine at nerve endings. The inhibitory activity of Boc-4-aminopiperidine can be determined using diagnostic techniques and it can be used to inhibit viruses such as HIV and influenza A virus.</p>

<p>Propylamine is a colorless, volatile liquid with a boiling point of -26.3°C. It has been shown to have the ability to react with sephadex g-100, which is a chromatographic material that separates proteins according to their size and charge. Propylamine has also been shown to undergo transfer reactions in the presence of hydroxyl groups and disulfide bonds. The chemical properties of propylamine have been studied using analytical methods such as nuclear DNA analysis, as well as biological studies involving the use of trifluoroacetic acid and nitrogen atoms for hydrogen bonding interactions.</p>

<p>4-Methylaminophenol sulfate is an enzyme substrate that is used in the analytical method for determining the concentration of potassium dichromate. It is prepared by reacting 4-methylaminophenol with sulfuric acid, and its optimum concentration is 0.2 mM. The linear calibration curve was obtained at a pH range of 2 to 5.4 and a temperature range of 25 to 37°C. The analytical method can be applied to human serum samples and has been shown to be applicable for studies on autoimmune diseases and anthelmintics.</p>

<p>Bosentan is a potent inhibitor of the uptake of organic anions. It is used in the treatment of pulmonary arterial hypertension and has been shown to be effective against pravastatin-resistant HIV protease inhibitors, such as saquinavir, quinidine, and rosuvastatin. Bosentan inhibits uptake by binding to the transporter protein at a site that does not overlap with the binding site for organic anion substrates. This leads to a change in kinetic parameters for substrates, such as pravastatin and saquinavir. The binding site on bosentan may also be elucidated through monolayer experiments with efflux transporters.</p>

<p>Dextroamphetamine saccharate is a pharmaceutical drug that belongs to the group of amphetamine derivatives. It is used in the treatment of conditions such as narcolepsy and attention-deficit disorder (ADD). The epidermal growth factor receptor (EGFR) is an important target for the effects of this drug, which has been shown to stimulate growth and proliferation in vitro. Dextroamphetamine saccharate has a complex pharmacokinetic profile and is metabolized by hydrolysis into dextroamphetamine. This drug also binds to voltage-dependent calcium channels, which regulate neurotransmitter release at nerve terminals. The pain relief associated with dextroamphetamine saccharate may be due to its ability to block pro-inflammatory cytokines or inhibit trigeminal nerve activity.</p>

<p>4-Aminopyrene is an aromatic amine that contains a nitro group. It has been used in biological studies to study the metabolism of amines, and chromatographic and mass spectrometric detection methods have been developed for its determination. 4-Aminopyrene also has the ability to form isomers through substitution on the N atom. The activation energy for this process is 14.3 kcal/mol. 4-Aminopyrene has been shown to be cytotoxic and mutagenic in vitro, and it can inhibit protein synthesis in bacteria by inhibiting RNA synthesis at the ribosome level. It has also been shown to induce changes in cell morphology and stimulate morphological differentiation of human promyelocytic leukemia cells (HL-60).</p>

<p>Please enquire for more information about N-(3-Aminopropyl)-2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Acetylamino-5-bromo-2-methoxy-benzoic acid methylester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tetrapropylammonium perruthenate is a polymeric matrix that contains a chelate ligand and can be used as an oxygen sensor. The polymer is synthesized in the presence of trifluoroacetic acid (TFA) using tetrapropylammonium chloride (TPACl) and perruthenate. Tetrapropylammonium perruthenate forms a polymeric matrix with TPACl, which contains a chelate ligand. The polymer is sensitive to changes in the environment such as pH, temperature, and oxidation-reduction potential. The polymeric matrix can be used for sensing the concentration of oxygen in liquid or gas phase by measuring fluorescence intensity at various wavelengths. These measurements are correlated with the concentration of oxygen in the environment.</p>

<p>Please enquire for more information about 5-Amino-4-methyl-4H-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Acetyl-6-(perfluoropropan-2-yl)-3-((pyridin-3-ylmethyl)amino)-3,4-dihydroquinazolin-2(1H)-one (PAFQ) is a mitochondrial cytochrome P450 inhibitor that inhibits the function of the ryanodine receptor and interacts with the piperonyl butoxide synergistically. PAFQ has been shown to be effective against animal pests such as termites, ants, and cockroaches. It also inhibits population growth in these populations by interfering with their ability to synthesize proteins. The effective dose for PAFQ varies depending on whether it is applied topically or orally.</p>

<p>2-(4-Morpholinophenyl)ethylamine is a fine chemical that is a versatile building block, useful intermediate, and research chemical. It is used in the synthesis of complex compounds, useful building blocks, and high quality reagents. The CAS registry number for 2-(4-morpholinophenyl)ethylamine is 930779-56-9.</p>

<p>[[4-[[2-(4-Cyclohexylphenoxy)ethyl]ethylamino]-2-methylphenyl]methylene]malononitrile (CAS #: 68436-91-7) is a reactive chemical species that has been used as a crosslinking agent and an uv absorption dye. CEM is a styryl dye that absorbs radiation in the uv range, with a maximum absorption at about 275 nm. It is a substrate film for light emission and can be used to measure viscosity. CEM is also chemically related to aromatic hydrocarbons and fatty acids, and can be synthesized from hydroxyl groups.</p>

<p>Benzydamine N-oxide is a polymorphic, michaelis-menten kinetics and pharmacological treatments drug. It has been shown to have anti-inflammatory effects in humans and animals. The main pharmacological targets of benzydamine are the human liver and alveolar type II cells. This drug has low bioavailability but is metabolized by the liver cells into benzydamine n-oxide which can be excreted through urine or bile. The formation rate of benzydamine n-oxide in the human body is about 2% per hour, which is dependent on the enzyme catalysis.</p>

<p>7-[(2S,3R)-3-Amino-2-methyl-azetidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-quinoline-3-carboxylic acid (ABT) is a drug that binds to bacterial enzymes and inhibits their ability to synthesize proteins. ABT is a conjugate of fluoroquinolone and an amino acid. As the drug is degradable by hydrolysis, it has been shown to be less toxic in Sprague Dawley rats than other fluoroquinolones. This drug has been used in diagnostic tests as a ligand for affinity ligands, but has not been approved for human use. The drug also possesses functional groups that are important for binding to reconstituted enzymes.br&gt;br&gt;ABT's ester linkages are degradable by hydrolysis and can be</p>

<p>Please enquire for more information about N-Phenylbenzene-1,3-diamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about [(5-Isopropyl-1,2,4-oxadiazol-3-yl)methyl]amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Aminogenistein is a molecule that has been shown to inhibit the growth of cancer cells. It has been shown to have a reactive functional group, which can be used as a diagnostic and prognostic tool for kidney disease and cancers. Aminogenistein has also been shown to inhibit epidermal growth factor (EGF) in rat kidneys, which may be due to its ability to bind EGF with high affinity. In addition, it has been shown to inhibit cellular physiology by blocking the transport properties of proximal tubules in rat kidneys. Aminogenistein is thought to induce apoptosis through the death protein pathway in cancer cells, but not normal cells.</p>

<p>(R)(−)-DOI hydrochloride is a synthetic compound classified as a selective serotonin receptor agonist. It is primarily sourced from chemical synthesis processes designed to explore potential interactions within serotonergic pathways. The compound’s mode of action involves the activation of 5-HT2A, 5-HT2B, and 5-HT2C serotonin receptors, which play crucial roles in modulating neurotransmission and signaling pathways within the central nervous system.In research and experimental contexts, (R)(−)-DOI hydrochloride is utilized to investigate the molecular mechanisms of serotonin receptors, contributing to a deeper understanding of their role in neurophysiology and potential implications in neuropsychiatric disorders. Studies often explore its effects on cognition, perception, and mood regulation. Despite its promising role in scientific exploration, (R)(−)-DOI hydrochloride is not intended for therapeutic use and remains predominantly a tool for advancing the field of neuropharmacology through controlled experimental settings.</p>

<p>Please enquire for more information about 3-[2-Amino-3-(2-tert-butoxycarbonyl-ethoxy)-2-(2-tert-butoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(5-Aminopentyl) methotrexate amide-LC-biotin is a specialized bioconjugate, derived through the conjugation of methotrexate, an established antifolate drug, with an LC-biotin moiety. This product is synthesized by covalently linking methotrexate, which is known for its role in cancer therapy through the inhibition of dihydrofolate reductase (DHFR), to a biotin moiety via a long-chain spacer. The resultant bioconjugate retains the therapeutic effects of methotrexate, particularly in its ability to interrupt nucleotide synthesis, thereby affecting cell division in rapidly proliferating cancer cells.The inclusion of biotin in the structure allows for facile attachment to avidin or streptavidin-labeled systems, facilitating targeted delivery and enhanced detection in molecular and cellular studies. The primary application of N-(5-Aminopentyl) methotrexate amide-LC-biotin lies in the realm of targeted drug delivery and advanced research into methotrexate metabolism. By leveraging the high affinity of biotin-streptavidin interactions, researchers can effectively study the biodistribution and cellular uptake of methotrexate, advancing cancer therapeutic strategies and providing insights into antifolate drug mechanisms at the molecular level.</p>

<p>8-Fluoro-Quinazoline-2,4-Diamine is an organic compound with the formula CHClN. It is a yellow solid that is soluble in organic solvents such as chloroform and toluene. The compound is used to produce dyes and pharmaceuticals. 8-Fluoro-Quinazoline-2,4-Diamine can be obtained by nitrating 2,4-diaminoquinazoline with nitric acid and hydrochloric acid in the presence of carbonate or stannous chloride. This reaction produces two isomers: 8-fluoroquinazoline (8FQ) and 6-fluoroquinazoline (6FQ). The 8FQ isomer has been shown to have a nuclear magnetic resonance spectrum at 300 MHz that contains four signals at 1.3 ppm, 3.5 ppm, 5.6 ppm, and 7.0 ppm, which are assigned to</p>

<p>Please enquire for more information about tert-Butyl 3-(aminomethyl)-1H-indole-1-carboxylate hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-[4-(1,2,4,5-Tetrazin-3-yl)benzylamino]-5-oxopentanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl2-(acetylamino)-3-[3,5-diiodo-4-(4-methoxyphenoxy)phenyl]propanoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>2-[(2,3-Dimethylphenyl)amino]nicotinic acid is an arylpropionic acid that has been designed for the treatment of cancer. It is a neutral compound that can be crystallized or sterilized and then injected or implanted into tissues. The compound can be used as a diagnostic tool to target specific tissues in the body by using iontophoresis or organic solvents. 2-[(2,3-Dimethylphenyl)amino]nicotinic acid interacts with chlorine ions to form a chloride derivative, which is then transported through the tissue. This process can be reversed by adding an acid solution to the tissue, which will cause the chloride ions to break down into hydrogen and chloride ions.</p>

<p>Please enquire for more information about 3-(Aminomethyl)-N,N-dimethyl-1,2,4-oxadiazole-5-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(+)(1S,2S,4R)-Bicyclo[2.2.1]heptane-2-amine is a heterocyclic compound that contains a nitrogen atom and an amine group. It has been shown to be a potent inhibitor of the enzyme activities of malonic acid decarboxylase and acetylcholinesterase. This compound can be used as a diagnostic tool for chronic kidney disease, specifically in cases of renal failure and polycystic kidney disease. The palladium complexes can be used for the synthesis of (+)(1S,2S,4R)-bicyclo[2.2.1]heptane-2-amine in high yield from malonic acid and ammonia.</p>