Ethers

<p>Applications 2,5-Dimethoxythiophenol is a thiophenol derivative used in the preparation of dihydrofolate reductase inhibitors and potential antitumor agents.<br>References Gangjee, A. et al.: J. Med. Chem., 52, 4892 (2009); Gangjee, A. et al.: Biiorg. Med. Chem., 18, 953 (2010);<br></p>

<p>Applications tert-Butyl (3-(2-(2-(3-Aminopropoxy)ethoxy)ethoxy)propyl)carbamate is used as a reactant in the synthesis of gallium-labeled PET imaging agents for CXCR4 for potential cancer diagnosis.<br>References Poty, Sophie, et al.: Bioconjugate Chem., 27(3), 752-761 (2016)<br></p>

<p>Applications Dimethoxy(methyl)silane (cas# 16881-77-9) is a useful research chemical.<br></p>

<p>Applications (2,3,4-Trimethoxyphenyl)boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer<br>References Hutschenreuter, T. et al.: J. Enz. Inhib. Med. Chem., 19, 17 (2004);<br></p>

<p>Applications 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is used in the preparation of selective bradycardic agents.<br>References Ye, X. et al.: Zhong. Yao. Xuax. Zaz., 20, 106 (2010);<br></p>

<p>Applications Methyl 2-Acetamido-2-(Dimethoxyphosphoryl)Acetate (cas# 89524-99-2) is a useful research chemical.<br></p>

<p>Applications B-[3-[[2-Hydroxy-3-[3-(triethoxysilyl)propoxy]propyl]amino]phenyl]boronic acid was prepared for the use as porous polymeric monolith for the specific capture of cis-​diol-​containing flavone under neutral condition.<br>References Pan, J., et al.: Chem. Eng. J., 317, 317-330 (2017);<br></p>

<p>Applications 3,4-Dimethoxybenzylamine (cas# 5763-61-1) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl 4-(trifluoromethoxy)benzoate<br></p>

<p>Applications (E)-1,1-Dimethoxybut-2-ene is a useful research chemical for organic synthesis and other chemical processes.<br>References Huot, J. F., et al.: Chem. Lett., 9, 1599 (1991); Mathew, S., et al.: Process Biochem., 501985 (2015)<br></p>

<p>Applications 3,4,5-Trimethoxyphenol is a useful synthetic intermediate in the synthesis of Thymonin (T413210); a flavonoid compound with potential antioxidant activity against peroxyl radicals.<br>References Dugas, A.J., et al.: J. Nat. Prod., 63, 327 (2000)<br></p>

<p>Applications Methoxy4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzenemethanol, is prepared synthetically from vanillin (V097500) with an intermediate of methoxy-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzaldehyde (M269710).<br>References Gowravarm, S. et al.: Adv. Synth. Catal., 343, 169 (2001)<br></p>

<p>Applications 1-[3,4-Bis(phenylmethoxy)phenyl]ethanone is an intermediate in synthesizing Arbutamine (A766300). It is a cardiac stimulant. Arbutamine stimulates adrenergic receptors.<br>References Sinusas, A., et al.: J. Nucl. Med., 35, 664 (1994); Sansoy, V., et al.: Circulation, 92, 994 (1995); Elhendy, A., et al.: Eur. J. Nucl. Med., 23, 1354 (1996);<br></p>

<p>Stability Hygroscopic<br>Applications Ethyl 3,3-diethoxypropionate<br></p>

<p>Stability Store at -20°C under Argon. Air Sensitive.<br>Applications 5,5-Diethoxypentanal (cas# 79893-96-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 3,5-Dimethoxyaniline (cas# 10272-07-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl (1R,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Ester is used in the discovery of a potent, selective and orally bioavailable dual CCR2 and CCR5 antagonist.<br>References Zheng, C., et al.: Bioorg. Med. Chem. Lett., 21, 1442-1446 (2011)<br></p>

<p>Applications 4,5-Dimethoxy-2-nitrobenzoic Acid (cas# 4998-07-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,5-Dimethoxybenzyl Alcohol can be used as a self-indicating standard for the determination of organolithium reagents<br>References Winkle, M.R. et al.: J. Chem. Soc. Chem. Comm., 3, 1980 (1980):<br></p>

<p>Applications 3,4-Dimethoxytoluene is a volatile flavor compound found is many substances such as boiled buckwheat flour, wild rice grain and tar of hickory wood smoke.<br>References Yajima, I., et. al.: Agr. Bio. Chem. 47, 729 (1983); Withycombe, D.A., et. al.: J. Agr. Food Chem., 26, 816 (1978); Hruza, D.E., et. al.: J. Agr. Food chem., 22, 123 (1974)<br></p>

<p>Applications 2,2-Diethoxy-N-ethylethanamine is used in the preparation of 1-substituted-2-mercaptoimidazoles with antithyroid activity.<br>References Jones, R.G.J. Am. Chem. Soc., 71, 4000 (1949)<br></p>

<p>Stability Volatile<br>Applications Methoxytrimethylsilane (cas# 1825-61-2) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Reagent used in Phthalimidooxy alylation.<br>References Yoda, R., et al.: Chem. Pharm. Bull., 42, 686 (1994), Kim, M., et al.: Bioorg. Med. Chem. Lett., 6, 2077 (1996),<br></p>

<p>Applications Intermediate in the production of modified guanine derivatives<br>References Kim, S., et al.: J. Med. Chem., 21, 883 (1978),<br></p>

<p>Applications 3,3-Diethoxy-1-propanol is used as a reactant in the synthesis of nanoparticles.<br>References Sumitani, Shogo, et al.: Reactive &amp; Func. Polymers, 71(7), 684-693 (2011);Kanakubo, Yurie, et al.: Colloids and Surfaces, B, 78(1), 85-91 (2010)<br></p>

<p>Applications [(Methoxy)methyl]triphenylphosphonium Chloride is used in the synthesis of Cephalotaxine (C261050), an antiviral and antitumor agent. Also used in the synthesis of Taxol A fragment.<br>References Sells, M., et al.: J. Virol., 62, 2836 (1988), Kaneko, S., et al.: J. Clin. Microbiol., 27, 1930 (1989), Baba, Y., et al.: Bioorg. Med. Chem., 13, 5164 (2005), Romero, M., et al.: Antiviral Res., 68, 75 (2005); Hirai, S. et al.: Tetrahedron Lett., 54, 1888 (2013); Xing, P. et al.: Synth., 45, 596 (2013);<br></p>

<p>Applications 1,4-Dimethoxybenzene is a useful chemical in organic synthesis.<br>References Digwal, Chander S., et al.: Asian J. of Org. Chem., 7(5), 865-869 (2018);Cai, Zhi-Bin, et al.: RSC Advances, 6(52), 46853-46863 (2016);Lin, Qi, et al.: Soft Matter, 13(39), 7222-7226 (2017)<br></p>

<p>Applications N-[1-[3-(2-Ethoxyphenyl)-2,5-dihydro-5-oxo-1,2,4-triazin-6-yl]ethyl]acetamide is an intermediate in the synthesis of Vardenafil (V098001) related compounds.<br>References Olszewska, T., et al.: Tetahedron., 69, 474 (2013);<br></p>

<p>Applications 3-(Phenylmethoxy)cyclobutanemethanol is a compound useful in organic synthesis.<br></p>

<p>Applications 3,4-Bis(phenylmethoxy)-benzoic Acid is a useful synthetic intermediate. It is an intermediate used to synthesize Jaboticabin (J210370) which is minor bioactive depside potent to treat chronic obstructive pulmonary disease.<br>References Wu, S., et al.: J. Agri. Food Chem., 61, 4035 (2013); Reynertson, K., et al.: J. Nat. Prod., 69, 1228 (2006)<br></p>

<p>Applications 3-ETHOXY-2-CYCLOHEXEN-1-ONE (cas# 5323-87-5) is a useful research chemical.<br></p>

<p>Applications trans-3,4,5,4'-Tetramethoxystilbene (cas# 134029-49-5) is a useful research chemical.<br></p>

<p>Applications 4,4'-Dimethoxydiphenylamine is a diphenylamine derivative used as a chemical additive for cured rubber. 4,4'-Dimethoxydiphenylamine is highly toxic and may potentially induce chromosome abberation.<br>References Kel'man, G.Y. et al.: Kauch. Rez., 26, 28 (1967); Sofuni, T. et al.: Mutat. res. Gen. Toxicol. Test., 24, 175 (1990);<br></p>

<p>Applications tert-Butyl (2-(methoxy(methyl)amino)-2-oxoethyl)carbamate has been used as a reactant in the preparation of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 with potential use in osteoarthritis therapy.<br>References Durham, T.B., et. al.: J. Med. Chem., 57, 10476 (2014)<br></p>

<p>Applications 2,2-Diethoxycycloheptanone is an intermediate in the synthesis of 1,2-Cycloheptanedione (C987255), a reagent in the synthesis of 3,3’-Polymethylene-2,2’-bibenzo[b]-1,10-phenanthrolines.<br>References Rahman, A. F. M., et al.: Heterocycles, 75, 871-877 (2008)<br></p>

<p>Applications 2-(1,1-Dimethylethoxy)-1-propanol is a useful reagent for organic synthesis.<br></p>

<p>Applications 4,4'-Dimethoxybenzhydrol acts as a reagent in the preparation of aryloxyacetamide derivatives and their biological activity as neuroprotective agents. Preparation and anticancer activity of quebecol and analogs.<br>References Zhong, Y., et al.: Bioorg. Med. Chem. Lett., 26, 2526 (2016); Pericherla, K., et al.: Bioorg. Med. Chem. Lett., 23, 5329 (2013)<br></p>

<p>Applications Tetramethoxypropane is a useful synthetic intermediate. It can be used to synthesize various compounds such as diiodonoradamantane and Salicylates[e.g. Salsalate(S095700)].<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ioannou, S., et al.: Tetrahedron Lett., 51, 2671 (2010); Sher, M., et al.: J. Org. Chem., 72, 6284 (2007)<br></p>

<p>Applications Synthesis and receptor binding of 5-(amino[3H]2methyl)-3-isothiazolol ([3H]thiomuscimol), a specific GABAA agonist photoaffinity label.<br>References Frolund, B., et al.: J. Labelled Compounds Radiopharm., 36, 877 (1995),<br></p>

<p>Stability Moisture Sensitive<br>Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.<br>References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);<br></p>

<p>Applications 2-[2-(2-azidoethoxy)ethoxy]ethanamine (cas# 166388-57-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N-[[4-(Phenylmethoxy)phenyl]methyl]-2-[(3-thienylcarbonyl)amino]-4-thiazoleacetamide is derived from ethyl 2-amino-4-thiaxolacetate (E899330) which is used in the synthesis of various pharmaceutical and biologically active compounds including inhibitors and antibiotics.<br>References Inamoto, Y., et al.: J. Antibiot., 41, 828 (1988)<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications 3,4-Bis(phenylmethoxy)benzeneethanamine is an intermediate used in the synthesis of S-(-)-Tretoquinol Hydrochloride (T798100), which belongs to the class of adrenergic inhalants, selective β-2-adrenoreceptor agonists. S-(-)-Tretoquinol is used in the treatment of obstructive airway diseases. S-(-)-Tretoquinol is a bronchodilator.<br>References Meshi, et al.: Biochem. Pharmacol., 19, 2937 (1970), Satoh, et al.: Chem. Pharm. Bull., 19, 667 (1971),<br></p>

<p>Applications 4,4'-Dimethoxystilbene is an intermediate in the synthesis of nonsteroidal, selective estrogen receptor modulator (SERM), Raloxifene (R100000).<br>References Liu, H., et al.: Chem. Res. Toxicol., 18, 162 (2005); Chen, Z., et al.: J. Org. Chem., 65, 8811 (2000);<br></p>

<p>Applications (3-Aminopropyl)trimethoxysilane is used in the synthesis of aspirin imprinted polymer on silica gel surface and appreciation on drug sustained release. Fluorine-doped; lectin functionalized ZnO nanoarrays as 3D nano-biointerface for bacterial detection.<br>References Lu, P., et al.: Gaofenzi Cailiao Kexue Yu Gongcheng, 33, 130 (2017); Zheng, L., Talanta, 167, 600 (2017)<br></p>

<p>Impurity Lubiprostone Impurity VI<br>Applications 7-((1R,2R,3R)-3-(cyclohexylmethoxy)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl)heptanoic Acid is a useful chemical reagent.<br></p>

<p>Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.<br>References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);<br></p>

<p>Applications Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is used in the preparation of dendronized polymers. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine can be used in the synthesis of optically degradable dendrons for temporary adhesion of proteins to DNA. It is also used in the preparation of tricylic polyamide receptor for carbohydrate recognition.<br>References Calderon, M. et al.: Macromol. Sym., 258, 53 (2007); Kostiainen, M.A. et al.: Chem. Eur. J., 16, 6912 (2010); Klein, E. et al.: Angew. Chem. Int. Ed., 44, 298 (2005);<br></p>

<p>Applications Bis[2-(2-chloroethoxy)ethyl] Ether, is an impurity in the synthesis of 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol (C365875), which is a polyethylene glycol used in the synthesis of novel glycolipids that bind HIV-1 cell surface glycoprotein Gp120 with potential application to pharmaceutical HIV-1 drugs. Also used in the synthesis of PET imaging agents targeting brain β-amyloid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References LaBell, R. et al.: Bioconj. Chem., 13, 143 (2002); Zhang, W. et al.: Nucl. Med. Biol., 32, 799 (2005);<br></p>

<p>Applications N10-(Ethoxycarbonyl)tryptamine is an intermediate in the synthesis of N-Methyltryptamine-d3 (M331922), which is a labeled N-Methyltryptamine, a N-monomethylated derivative of tryptamine. N-Methyltryptamine, unlike its unmethylated counterpart, does not produce any psychoactive effects. High levels of N-Methyltryptamine have been found in cisternal cerebrospinal fluid of patients with acute paranoid schizophrenia.<br>References Schmid, C. et al.: J. Neurosci., 30, 13513 (2010); Uebelhack, R. et al.: Biomed. Biochim. Acta, 42, 1343 (1983);<br></p>

<p>Applications 3,5-Dimethoxytoluene (cas# 4179-19-5) is a useful research chemical.<br></p>

<p>Applications Methyl 2-Ethoxy-5-(ethoxysulfonyl)benzoate is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications Cis-1-Bromo-2-ethoxyethylene<br></p>

<p>2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid is a metabolite of levodopa in the body. It is formed by oxidation of levodopa via the enzyme catechol-O-methyltransferase (COMT). This compound is used as an analytical reagent to measure levels of levodopa and its metabolites in biological samples. 2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid can also be used to diagnose Parkinson’s disease, since it is produced in excess when dopamine production decreases due to the degeneration of dopaminergic neurons. The concentration–time curve for this compound can be used to calculate the clearance rate of levodopa from the blood plasma.</p>

<p>2,5-Dichloro-4-methoxybenzoic acid is a synthetic herbicide that inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). This enzyme is necessary for the synthesis of aromatic amino acids. 2,5-Dichloro-4-methoxybenzoic acid is used as a selective herbicide in plants grown in vitro to eliminate weeds. It is also used to control populations of wild plants and grasses. 2,5-Dichloro-4-methoxybenzoic acid has been shown to inhibit the growth of glyphosate resistant weed species by inhibiting EPSPS activity.</p>

<p>1,1,3,3-Tetraethoxypropane is a fatty acid that is produced by the metabolism of plant and animal lipids. It has been used as a food additive to bind water and improve texture in baked goods. It also has shown to have antioxidant properties. In addition, 1,1,3,3-Tetraethoxypropane has been shown to be reactive with human feces and inhibit enzyme activities in infectious diseases. This compound is also an autoimmune disease agent that inhibits physiological activities in humans. The bound form of 1,1,3,3-Tetraethoxypropane can be found in human serum and liver cells.</p>

<p>Please enquire for more information about N-Ethyl-4-methoxy amphetamine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Boc-(S)-3-amino-3-(2-methoxyphenyl)propionic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Amino-4'-methoxydiphenylamine HCl is a chemical compound that can be used as an analytical tool. It is prepared by the reaction of 4-aminophenol with 4-chloromethylphenol and formaldehyde in the presence of hydrochloric acid. This product has been found to have a potentiodynamic polarization curve that resembles that of a cationic surfactant. The detection methods for this product are electrochemical impedance spectroscopy, microscopy, and chemical reactions.</p>

<p>This is a crystalline form of the pyrimidine derivative (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid. The compound has been shown to have antiplatelet properties and is currently being developed as an antithrombotic agent. In vitro studies have shown that ambrisentan inhibits platelet aggregation, thromboxane synthesis, and leukocyte adhesion. It also reduces the levels of serum cholesterol and triglycerides in patients with chronic heart failure. Ambrisentan has been studied in clinical trials for the treatment of pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).</p>