Organoboranes

<p>Applications 1,1,3,3,5,5,7,7,9,9,11,11-DODECAMETHYLHEXASILOXANE (cas# 995-82-4) is a useful research chemical.<br></p>

<p>Applications Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Driscoll, J.S. et al.: J. Med. Chem., 34, 3280 (1991); Pan, L. et al.: J. Pharm. Biomed. Anal., 52, 589 (2010);<br></p>

<p>Applications Hydrogen Tetrafluoroborate(1-) is a useful building block for organic synthesis.<br>References Ohkuma, T., et al.: Journal of the American Chemical Society., 218, 8724 (2006)<br></p>

<p>Applications 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isophthalonitrile, is an intermediate used for the synthesis of more complex compounds.<br></p>

<p>Applications OCTADECYLTRIETHOXYSILANE (cas# 7399-00-0) is a useful research chemical.<br></p>

<p>Applications (E)-2-(1-Butenyl)-1,3,2-benzodioxaborole (cas# 106094-36-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Decaborane is a useful building block mostly used in the preparation of carboranes. On its own, Decaborane is able to undergo reduction via acetate as a neat liquid.<br> E0<br>References Marsh, A. V.; et al.: Angew. Chem. Int. Ed., 57, 10640 (2018); Kelley, S. P.; et al.: ACS Omega, 3, 8491 (2018).<br></p>

<p>Applications A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products. Used in dermal exposure and inhalation toxicity study.<br>References Wang, R. et al: Env. Int., 35, 900 (2009); Johnson, B. et al.: Chem. Ind. Digest, 23, 79 (2010); Reddy, M.D, et al.: Toxic. Sci., 105, 275 (2008);<br></p>

<p>Applications Octamethyl-1,7-tetrasiloxanediol, can be used in the preparation of Silicone coated Celgard-2400 for the adhesion of canine platelets and leucocytes.<br>References Chawla, A. S.: Biomaterials, 2, 83 (1981)<br></p>

<p>Applications Triisopropylsilane is used in the design of internalizing PSMA-specific Glu-ureido-based radiotherapeuticals for prostrate cancers. Reagent for the rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight. Also functions as a highly selective reducing agent used in the preparation of anti-1,2-diols.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wuestemann, T., et al.: Theranostics, 6, 1085 (2016); Kilian, T., et al.: J. Med. Chem., 58, 4180 (2015); Horners, L.; et al.: Organomet. Chem., 282, 155 (1985)<br></p>

<p>Applications Di-tert-butyldichlorosilane (cas# 18395-90-9) is a useful research chemical.<br></p>

<p>Applications tert-Butyldiphenylchlorosilane is used to synthesize interphenylene phenyloxazoles, compounds that have antagonistic activity against thromboxane receptors which can be used for treatment of circulatory disorders, angina and stroke.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hadjipavlou–Litina, D. &amp; Kontogiorgis, C.: Int. Elect. J. Mol. Des., 1, 300 (2002); Misra, R., et al.: Bioorg. Med. Chem. Lett., 2, 937 (1992)<br></p>

<p>Applications 3-Carboxyphenylboronic Acid is used in phenylboronic acid-decorated gelatin nanoparticles for enhanced tumor targeting and penetration.<br>References Wang, X., et al.: Nanotechnology, 27, 385101 (2016); Wang, X., et al.: Eur. J. Pharm. Biopharm., 113, 168 (2017)<br></p>

<p>Applications N,O-Bis(trimethylsilyl)acetamide is used as a reagent in the synthesis of 4'-spirocyclic phosphono-nucleosides as potential inhibitors of hepatitis C virus NS5B polymerase. Also used as a reagent in the microwave-assisted synthesis of purine nucleosides as selective cholinesterase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dang, Q., et al.: Tetrahedron Lett., 55, 4407 (2014); Schwarz, S., et al.: Org. Biomol. Chem., 12, 2446 (2014)<br></p>

<p>Applications Hexamethylcyclotrisiloxane is used in the preparation of Silicone coated Celgard-2400 for the adhesion of canine platelets and leucocytes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chawla, A.S.: Biomaterials, 2, 83 (1981)<br></p>

<p>Applications (1-acetyl-2,3-dihydro-1H-indol-5-yl)boronic acid (cas# 905971-97-3) is a useful research chemical.<br></p>

<p>Applications Vinyltrimethoxysilane (cas# 2768-02-7) is a useful research chemical.<br></p>

<p>Applications A non-cyclic polydimethyl siloxane. Study shows that it can be transformed by a specific microflora and in the natural environment degraded by mechanisms similar to other organic compounds.<br>References Watanabe, N. et al.: Ecotoxic. Env. Safety, 11, 174 (1986); Wasserbauer, R. et al.: Folia Microbiologica, 35, 384 (1990);<br></p>

<p>Applications Trimethylsilyl azide is used to mediate Schmidt rearragement reactions and is also used as a nucleophile in organic synthesis. Versatile azidonation reagent for amines, amides, aldehydes, and ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mphahlele, M.: J. Chem. Soc. Perk. T. 1, 23, 3477 (1999); Pastor, I. &amp; Yus, M.: Org. Chem., 9, 1 (2005)<br></p>

<p>Applications Trimethoxy(octyl)silane is a surface modifier used as additive for polymer encapsulation and for controlled drug delivery.<br>References Erdem, B., et al.: Langmuir, 17, 2664 (2001); Doadrio, J., et al.: J. Mater. Chem., 16, 462 (2006);<br></p>

<p>Applications Triphenylsilanethiol is a useful organic building block used for carboxyl activation via silylthioesterification, and in the preparation of synthesis of tetraphenylporphyrinate manganese(III) siloxides.<br>References Lamar, A. A.; et al.: Tetrahedron Lett., 56, 6034 (2015); Meininger, D. J.; et al.: J. Coord. Chem., 69, 1970 (2016).<br></p>

<p>Stability Moisture Sensitive<br>Applications 1-(Trimethylsiloxy)cyclohexene is used as a reagent in the synthesis of 6-Methyl Chrysene (M265140); an aryl hydrocarbon receptor (AhR) agonist that has been listed as possibly carcinogenic to humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Amin, S. et al.: Cancer Res., 45, 6406 (1985); Blaha, L. et al.: Toxicol. Sci., 65, 43 (2002); Brack, W. et al.: Environ. Sci. Technol., 37, 3062 (2003); Andrysik, Z. et al.: Mutat. Res., 615, 87 (2007)<br></p>

<p>Applications Used to protect alcohols during organic synthesis.<br>References Shen, H., et al.: J. Med. Chem., 53, 2666 (2010), Qiang, L., et al.: Bioorg. Med. Chem. Lett., 20, 836 (2010),<br></p>

<p>Applications Hydroxydi-p-tolylborane is a building block used as a reactant in the nickel-catalyzed cross-coupling of diarylborinic acids with aryl chlorides.<br>References Chen, X., et al.: ACS Catalys., 4, 379 (2014);<br></p>

<p>Stability Moisture Sensitive<br>Applications Tris(trimethylsiloxy)silane functions as a modified siloxane elastomer for controlled cell growth or as a biomaterial surface that induces a desired cellular response.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gibson, A. L., et al.: Mater. Res. Soc. Symp. Proc., 711, 169 (2002)<br></p>