Amides

<p>N-[2-(1,3-Dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide is an herbicide that belongs to the group of fatty acid amides. It is a selective postemergence herbicide that inhibits the germination and growth of plants by inhibiting the synthesis of fatty acids. Unlike other chemical pesticides, it has no effect on animals or humans and it is not toxic to plants. The selectivity of N-[2-(1,3-Dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide makes it a good candidate for use in combination preparations with other chemicals.</p>

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<p>N-[(3S)-2,5-Dioxotetrahydro-3-furanyl]-2,2,2-trifluoroacetamide is a boronic acid that has been used to synthesize polymers. This compound is of interest for the synthesis of hydrophobic amino acids such as threonine and lysine. The high yield and functionalisation of this molecule make it deserving of further investigation.</p>

<p>Anthranilamide is used for non-selective, efficient fluorescent labelling of glycans.</p>

<p>Glycine amide acetate is a product that contains an imine group. It has been shown to have staining properties when applied to human keratin and is used in the cosmetic industry as a depigmenting agent. Glycine amide acetate has been shown to be effective in the treatment of depression, although it is not yet approved for this use. The molecule also contains an iridoid compound, which may be responsible for its effects on mood.</p>

<p>1-Methyl-1,4-dihydronicotinamide (1MDNA) is a flavine adenine dinucleotide analog that has been shown to be a potent inhibitor of the enzyme catalase. 1MDNA binds to the active site of the enzyme and prevents hydrogen peroxide from being converted into water and oxygen. This inhibition slows down or stops the reaction, which leads to reduced production of reactive oxygen species. 1MDNA inhibits other enzymes in a similar manner, including transferases and kinases. The kinetic properties of 1MDNA have been studied by performing kinetic studies on model systems at different temperatures. X-ray crystal structures have also been obtained for 1MDNA bound to catalase and ferredoxin.</p>

<p>Tris[N-ethyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-heptadecafluoro-N-(2-hydroxyethyl)-1-octanesulfonamide] phosphate is a sulfonate that has been mixed with other chemicals. It is used as a chemical substance for the production of other substances. Tris[N-ethyl-1,1,2,2,3]3,[4],4,[5],5,[6],6-[7],7,[8],8-[heptadecafluoro-N-(2-hydroxyethyl)-1-octanesulfonamide] phosphate has not been classified by the International Agency for Research on Cancer (IARC).</p>

<p>This compound is a recyclable, multicomponent, element analysis, element, diversity and catalyzed reaction that yields high purity products with high yields. The catalyst is reusable and the NMR data are reproducible.</p>

<p>4-Chloro-3,5-dinitrobenzamide is a bifunctional molecule that contains a chlorine atom. It has been found to react with dipolar solutes as well as vicinal dioxan arylation. The nucleophilic amide group is also labile and can be hydrolyzed by strong acids or bases. The electron lone pair of the chlorine atom in 4-chloro-3,5-dinitrobenzamide can be used for electrophilic substitution reactions with aromatic rings or amines. This molecule has been found to undergo an arylation reaction with imidazole in the presence of dioxan solvent at room temperature.</p>

<p>4-Hydroxyphenylacetamide is a natural product that has been shown to have antibiotic properties. It inhibits the growth of bacteria by inhibiting the synthesis of p-hydroxybenzoic acid, which is an essential precursor for the biosynthesis of aromatic amino acids and other important compounds. 4-Hydroxyphenylacetamide also inhibits dopamine oxidation, which may lead to its anti-infective properties. The biological properties of 4-hydroxyphenylacetamide have been studied using electrochemical impedance spectroscopy (EIS) on bacterial strains and in vitro studies on P. aeruginosa. This compound is not metabolized by microorganisms and does not mineralize or react with oxygen at physiological pH levels. It can be used as a pharmaceutical dosage form for treatment of infectious diseases.</p>

<p>Chemically a chlorinated salicylanilide, niclosamide is clinically used as an anthelmintic agent. The action of niclosamide has been proven to proceed by inhibiting the STAT3 signaling pathway. Recently, niclosamide, has been considered as an antiproliferative agent in cancer treatment, e.g. melanoma and colorectal cancer. In 2021, niclosamide has been tested for the treatment of COVID-19 patients.</p>

<p>N-Benzylbenzamide is a molecule that contains an amide group, which is considered to be a hydrogen bond acceptor. The amine group of this compound can also act as a hydrogen bond donor. It has been shown to inhibit the activity of tyrosinase, which is an enzyme responsible for the production of melanin in melanocytes. N-Benzylbenzamide has been shown to have a molecular mechanism similar to that of hydroquinone and other phenolic compounds. In addition, it has been found to decrease microvessel density and inhibit the growth of cancer cells in vitro. This compound is not yet approved for use as a drug but may be used in future research studies as an alternative treatment for cancer.</p>

<p>3-Aminobenzamide is a drug that has been shown to be effective in the treatment of temozolomide-induced neuronal death. 3-Aminobenzamide inhibits the synthesis of ATP and blocks its binding to the atp-binding cassette transporter, which prevents the transport of this nucleotide into cells. This results in cell death due to insufficient energy metabolism and inability to repair DNA damage. 3-Aminobenzamide also increases production of reactive oxygen species, which are involved in reperfusion injury and myocardial infarcts. 3-Aminobenzamide is used as a model system for studying DNA repair and energy metabolism.</p>

<p>2-Amino-5-methylbenzamide (2AMB) is a potent inhibitor of the enzyme dihydropyrimidine dehydrogenase and is used in cancer research for its ability to inhibit tumor cell line growth. 2AMB has been shown to inhibit the synthesis of DNA, RNA, and protein in various human cell lines. The mechanism of this inhibition is not well understood, but it may be due to its ability to inhibit the activity of synthetases involved in nucleotide biosynthesis or by inhibiting the reaction system that converts hydration into ATP.</p>

<p>Piperazinophenylacetic acid benzylamide hydrochloride is a versatile building block that can be used in the synthesis of complex compounds for research and development. It is a reagent for the preparation of speciality chemicals and also a useful intermediate for the synthesis of reaction components. Piperazinophenylacetic acid benzylamide hydrochloride is a high quality, commercially available chemical that can be used as a scaffold for the preparation of new chemical compounds.</p>

<p>Tolbutamide is a drug that is used to treat diabetes mellitus type 2. It is an inhibitor of the enzyme glucokinase and thus blocks the phosphorylation of glucose, which prevents its utilization by cells. This results in a decrease of blood glucose levels, which can be useful in the treatment of diabetes mellitus type 2. Tolbutamide has shown potent apoptosis-inducing effects on human breast cancer cells and endothelial cells. These effects are thought to be due to inhibition of protein kinase C (PKC) activity by tolbutamide. Additionally, this drug inhibits insulin secretion from pancreatic beta cells and induces cytochrome P450 enzymes, which may lead to increased metabolism of other drugs.</p>

<p>Thioctamide is a drug that belongs to the class of drugs called sulfonylureas. It is an anti-diabetic drug that has been used for the treatment of insulin-resistant type II diabetes. Thioctamide binds to mitochondrial dehydrogenases and lipoamidases, inhibiting mitochondrial functions and energy metabolism. This leads to a decrease in cellular ATP levels, which can be measured by electrochemical impedance spectroscopy (EIS). The effects of thioctamide on cells can also be determined by examining the response of cells to different concentrations of thioctamide using a cell viability assay. This drug has been shown to inhibit the growth of HL60 cells, with IC50 values ranging from 2.6 µM to 6.4 µM depending on concentration. Thioctamide inhibits the expression of toll-like receptor 4 (TLR4) and integrin receptor β1 in HL60 cells, which may be due to its ability to act</p>

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<p>4-Aminothiobenzamide (4ATB) is a chemical compound that is used as an anticancer agent and an antimicrobial agent. It has been shown to have antitumor activity against human liver cancer cells and anticancer activity against human adrenergic receptor-positive lung cancer cells. 4ATB binds to the chloride ion present in the cell membrane, which prevents the influx of chloride ions into the cell. This leads to an increase in intracellular pH and disruption of cellular functions. 4ATB has also been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) infections by inhibiting bacterial growth and reducing the production of proteins vital for cell division.</p>

<p>2-Phenylbenzamide (2PB) is a drug that belongs to the class of anthelmintics. It binds to the nicotinic acetylcholine receptor and inhibits the release of acetylcholine at neuromuscular junctions, leading to paralysis and death of the parasite. 2PB also has been shown to have anti-inflammatory properties in mice with colitis, which may be due to its ability to inhibit prostaglandin synthesis. The molecular docking analysis showed that 2PB binds covalently with nitro-containing molecules, such as nitrosamines, which are found in cigarette smoke and are known carcinogens. This binding may contribute to the development of cancer through inhibition of DNA repair mechanisms.</p>

<p>4-Nitrobenzamide is a chemical substance that belongs to the class of nitrobenzamides. It is used as an intermediate in the synthesis of other substances, such as pharmaceuticals, herbicides, and pesticides. 4-Nitrobenzamide was first synthesized in 1894 by hydrogenating nitrobenzoic acid with hydrogen chloride in the presence of phosphorus pentachloride. The reaction vessel for this process should be made of glass or porcelain due to the corrosive nature of hydrogen chloride gas. The kinetics for this reaction were studied using concentration-response curves on rats and mice at different concentrations. Acute toxicities observed include respiratory distress and death in rats and convulsions and death in mice.<br>4-Nitrobenzamide is also toxic to bacteria, which can be seen by its effect on Staphylococcus aureus (strain ATCC 25923). This strain had a 50% survival rate after exposure</p>

<p>Dodeca 2E,4E,8Z,10E,Z-tetraenoic acid isobutylamide (DETBA) is a versatile building block that is used in the synthesis of natural products and pharmaceuticals. DETBA can be used as a reaction component in organic synthesis to form complex compounds such as polyesters, polyamides, polyurethanes, and polyimides. It also has high quality and can be used in research or speciality chemical applications.</p>

<p>5-Iodosalicylamide is a chemical building block. 5-Iodosalicylamide can be reacted with appropriately functionalised aromatic compounds to afford the corresponding anilides, which have been shown to exhibit anti-fungal and bactericidal properties.</p>

<p>The drug 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (BZP) is a histamine H2 receptor antagonist. It binds to the histamine H2 receptor in the stomach and duodenum, thereby blocking stomach acid production. BZP has been shown to be effective for treating symptoms of constipation or diarrhoea caused by inflammatory bowel disease or abdominal surgery. BZP also reduces the risk of relapse after surgery but does not affect long term efficacy. This drug is not available in the United States and has significant interactions with other drugs and symptoms including constipation, bowel disease, long term efficacy, and analytical method.</p>

<p>2,2,2-Trifluoro-n-phenylacetamide is a functionalized trifluoroacetic acid. It is inactive and can be used for diagnostic purposes. 2,2,2-Trifluoro-n-phenylacetamide reacts with amines to form the corresponding deuterium isotope labeled amine. The heterocyclic amines that are formed react with diazonium salt to produce an enolate anion that reacts with chloride to form the corresponding carboxylic acid derivative. The proton of the carboxylic acid leaves as a protonated ammonium ion, which is stable in alkaline solutions. Amides have a negative charge on the nitrogen atom due to its electron withdrawing properties.</p>

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<p>N-[2-Iodoethyl]trifluoroacetamide is a reactive alkylating agent that is used in the synthesis of biologically active molecules. It reacts with lysines, tryptic and other amino acids to form covalent bonds, which can be cleaved by hydrolysis. The compound also reacts with sulfhydryl groups to produce sulfonium ions, which react with the thiol group at position C6 on the sarcoplasmic reticulum Ca2+ -ATPase to inhibit muscle contraction. N-[2-Iodoethyl]trifluoroacetamide has been shown to cause allergic reactions in rats, mice, and guinea pigs. This drug has also been observed to have an effect on the central nervous system when administered at high doses.</p>

<p>N,N'-Diallyl-L-tartardiamide is a heparin-like molecule with the ability to bind calcium. It has been shown to be an effective inhibitor of antibody response in mice and can also inhibit periodate treatment of primary amino groups. N,N'-Diallyl-L-tartardiamide has a high degree of solubility in water and is soluble in organic solvents as well. It can be crosslinked to form polymeric matrices that are suitable for use in size-exclusion chromatography. N,N'-Diallyl-L-tartardiamide can also be used as a cross linking agent for agarose gels and gel matrices.</p>

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<p>Clofenamide is a drug that is used to treat insulin resistance. It is an at1 receptor antagonist that blocks the action of histamine, which stimulates the release of insulin from the pancreas. Clofenamide has been shown to reduce systolic blood pressure in patients with autoimmune diseases and cardiac hypertrophy. It is also used for treating infectious diseases, such as pneumonia and tuberculosis. Clofenamide reduces inflammation by inhibiting inflammatory enzymes, such as butyric acid. This drug has been found to have anticancer activity in cell-based studies by inhibiting cellular proliferation and inducing apoptosis in cancer cells.</p>

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<p>2,6-Dimethoxy-3-nitrobenzamide is a fine chemical that is used as an intermediate in the synthesis of other compounds. This material can be used to make pharmaceuticals and research chemicals, such as antibiotics and pesticides. 2,6-Dimethoxy-3-nitrobenzamide is a versatile building block that can be used for the production of many different compounds. It has a CAS number of 55776-15-3 and has been assigned the Chemical Abstracts Service (CAS) registry number of 71887-92-8.</p>

<p>Agonist of D2 dopamine receptors</p>

<p>N-Methyl-4-pyridone-3-carboxamide is a nonnutritive sweetener that has been shown to have no effect on peroxisome proliferation. It also had no effect on the levels of fatty acids in rat cardiomyocytes and did not affect uv absorption. N-Methyl-4-pyridone-3-carboxamide binds to the receptor α subunit of the taste receptor and inhibits adenosine uptake, which may be responsible for its effects on depression. This compound also alters energy metabolism by inhibiting mitochondrial ATP production and glycolysis.</p>

<p>Polyamide is a synthetic polymer that contains amide bonds. It is characterized by high water vapor permeability, low water solubility, and good chemical stability. Polyamide has been shown to have growth factor-β1 activity in vitro and in vivo for the treatment of tubulointerstitial injury. Polyamide is also used as a template for the synthesis of DNA. It has been shown to have antioxidant properties and inhibit prostate cancer cells. The polyamide chain can be analyzed using monoclonal antibodies and structural analysis methods such as nuclear magnetic resonance spectroscopy, infrared spectroscopy, x-ray diffraction, or electron microscopy.</p>

<p>N-(5-Cyano-2-chlorophenyl)acetamide is a high quality, reagent, and versatile building block. It is a fine chemical that can be used as a building block for the synthesis of other compounds. N-(5-Cyano-2-chlorophenyl)acetamide is also a speciality chemical that can be used in research or as a reaction component. It has been found to be useful as an intermediate in the synthesis of complex compounds.<br>END&gt;</p>

<p>2-Methylbenzamide is an amide with a carbonyl group and an intramolecular hydrogen. It has been shown to have synergic effects when combined with piperonyl butoxide in the treatment of autoimmune diseases. This synergistic effect is due to the inhibition of inflammatory mediator release, which can be achieved by blocking the enzyme cyclooxygenase-2. 2-Methylbenzamide has also been shown to inhibit deuterium isotope effect in cd-1 mice, which could make it beneficial for patients who are unable to tolerate other drugs.</p>

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<p>(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide is a reagent and research chemical that can be used as a building block in the synthesis of other compounds. It is also a versatile building block in organic chemistry. (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide has been shown to be an effective intermediate for the synthesis of various complex compounds, such as pharmaceuticals and pesticides. This compound is also a useful scaffold for the synthesis of other fine chemicals.</p>

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<p>3,5-Dihydroxybenzamide is an amide derivative that has anticancer activity. This compound inhibits the growth of C. glabrata by inhibiting protein synthesis in the mitochondria and DNA replication in the nucleus. 3,5-Dihydroxybenzamide also inhibits the growth of cancer cells by binding to a molecule that is involved in cancer cell proliferation. The inhibitor molecule binds to a specific site on the molecule, preventing it from forming new cancer cells. The mechanism of action for this compound is not known, but may be due to its ability to bind with chloride ions or its ability to form supramolecular chemistry with other molecules.</p>

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<p>N-(5-Bromoacetamidylpentyl) acrylamide is employed in the synthesis of substrates used for nucleotide sequence determination, covalently linked to polymer coatings such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM). Polynucleotide-binding substrates find application as molecular arrays and flow cells.</p>

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<p>Labetalol is a β-blocker that is used to treat high blood pressure. Labetalol hydrochloride, the active form of labetalol, is a white, crystalline compound with a melting point of 200 °C. It is soluble in water and has an acidic pH of 2. Labetalol hydrochloride is synthesized by reacting methylbenzene with labetalol, which forms intermediates such as methyl 4-hydroxylbenzoate and methyl 3-hydroxylbenzoate in the process. The intermediates are then recrystallized to form the final product. Labetalol hydrochloride undergoes thermal analysis using thermogravimetry, calorimetry, and residue analysis to determine its purity. This product also undergoes carbonaceous and oxidative analysis by GC-MS for quality control purposes.</p>

<p>2-(3-Hydroxyphenyl)acetamide (2HPA) is a sulfonamidochrysoidine compound with analgesic, antipyretic and anti-inflammatory effects. It is used in the treatment of gout, rheumatoid arthritis, osteoarthritis and other inflammatory diseases. 2HPA has been shown to be effective in the treatment of pain following dental surgery. 2HPA is also used as a marker for dietary intake of sulfate and may be a useful indicator for determining the effect of changes in diet on urinary excretion rates. The elimination half-life of 2HPA is approximately 3 hours in humans. This drug can be detected in urine samples from humans within 24 hours after ingestion at concentrations that are proportional to dose.</p>

<p>4-Bromobenzamide is an amide with a hydrogen bond that inhibits the activity of proteases. It has been shown to inhibit the activity of cathepsin C and chymotrypsin in vitro, as well as the proteolytic activity of elastase. 4-Bromobenzamide also has a covalent inhibition effect on protein synthesis. This inhibitor is capable of reducing the levels of glutathione reductase, cytochrome P450, and mycobacterium in cell culture. In addition, 4-bromobenzamide has been shown to have acute toxicities in mice and rats when administered at high doses. However, it does not show any toxic effects on healthy mice or rats when administered at low doses.</p>

<p>N-Benzyl Hexadecanamide is a long-chain amide that is used in analytical chemistry as a sample preparation agent and to extract fatty acids from biological samples. It has been shown to have neuroprotective properties by reducing the uptake of glutamate and preventing neuronal cell death. N-Benzyl Hexadecanamide has also been found to prevent tumor growth and induce apoptosis in human cancer cells, which may be due to its ability to inhibit creatine kinase activity. This compound has also been shown to have anti-inflammatory effects, which are mediated through the inhibition of the activation of nuclear factor kappa B (NF-κB).</p>

<p>2-Amino-N-[2-(2-chlorobenzoyl)-4-nitrophenyl]acetamide is a fine chemical that is used as a building block in organic synthesis. It is a versatile intermediate for the synthesis of other compounds and can be used to make a variety of useful scaffolds. 2-Amino-N-[2-(2-chlorobenzoyl)-4-nitrophenyl]acetamide has been used in research and development of pharmaceuticals, agrochemicals, herbicides, and other compounds.</p>