Carboxylic Acids

<p>Applications 4-(2,2,3-Trimethylcyclopentyl)butanoic Acid is used in preparation of Alicyclic compounds as off-note masking agent in consumables.Is used in preparation of 4-(2,2,3-Trimethylcyclopentyl)butanoic Acid as an off-note masking agent in consumables.<br>References Slack, Jay P., et al.: U.S., (2013); Slack, Jay P., et al.: PCT Int. Appl., (2008);<br></p>

<p>Applications Opianic Acid is a reagent used in the synthesis of novel 5-arylidene (thio)barbituric acid displaying urease activity.<br>References Vosooghi, M. et al.: J. Iran. Chem. Soc., 12, 1487 (2015);<br></p>

<p>Applications Hydrazine acetate (cas# 7335-65-1) is a useful research chemical.<br></p>

<p>Applications 2-Benzoylbenzoic Acid is a reagent that is used in the synthesis of BzATP Triethylammonium Salt, which is a selective P2X purinergic agonist. It is more potent than ATP at homodimeric P2X7 receptors.<br>References Abou-Seri, S. M., et al.: Eur. J. Med. Chem., 107, 165 (2016);<br></p>

<p>Applications Fumaric Acid is a compound that occurs in many plants. It is essential to vegetable and tissue respiration and also used as an antioxidant. Fumaric Acid is also a metabolite of Dimethyl Fumarate (D464965), a compound used as a treatment for the relapsing forms of multiple sclerosis and psoriasis.<br>References Jelitto, T., et al.: Planta, 188, 238 (1992); Schimrigk, S., et al.: Eur. J. Neurol., 13, 604 (2006); Son, H., et al.: J. Agric. Food Chem., 56, 8007 (2008);<br></p>

<p>Stability Volatile<br>Applications 2-Pentyl Acetate has a weak banana odor. 2-Pentyl Acetate is an irritant.Environmental contaminants; food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dong, T., et al.: J. Hortic. Sci. Biotechnol. 89, 441 (2014); Xu, Z., et al.: Food Bioprocess Tech 9, 407 (2016)<br></p>

<p>Applications o-Arsanilic Acid is an organoarsenic compound. o-Arsanilic Acid is a highly toxic contaminant and can be found in plants growing in contaminated soil.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schmidt, A.-C. et al.: Chemosphere, 73, 1781 (2008);<br></p>

<p>Applications Dihydroresorcylic Acid is a useful reagent in detecting proteins in living cells.<br>References Reddie, K., et al.: Mol. Biosys., 4, 521-531 (2008); Seo, Y., et al.: Bioorg. Med. Chem. Lett., 19, 356-359 (2009);<br></p>

<p>Applications Ethyl 2-Mercaptoacetate is an off-odor compound in white wine and an eye irritant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nikolantonaki, M., Darriet, P.: J. Agr. Food Chem., 59, 10191 (2011); Bagley, D.M., et. al.: Toxicol. in vitro, 13, 505 (1999)<br></p>

<p>Applications Isotope labelled Trifluoroacetic Acid used as a solvent in a variety of organic synthesis and chemical processes. Used in the synthesis of anticancer agents as well as phospholipase D inhibitors.<br> E0<br>References Scott, S. et al.: Nat. Chem. Biol., 5, 108 (2009); Minko, T. et al.: Cancer. Chemother. Pharmacol., 50, 143 (2002);<br></p>

<p>Applications 2,6-Diaminopimelic Acid is useful in biological studies involving amino acids and amino sugars as molecular indicators of the origins of organic matter in buried tephra soils.<br>References Hobara, S., et al.: Geoderma, 373, 114449 (2020)<br></p>

<p>Applications 2-Ethoxybenzoic Acid is a component of dental cement. Low concentrations of 2-Ethoxybenzoic Acid in combination with Eugenol (E938640), gives a stabilizing effect to liposomes to lower damages to cells.<br>References Fujisawa, S., et al.: J. Dent. Res., 82, 43(2003); Brauer, G.M., et al.: J. Dent. Res., 62, 366 (1983); Brauer, G.M., et al.: J. Dent. Res., 63, 137 (1984); Fujisawa, S., et al.: J. Biomed. Mater. Res., 21, 89 (1987)<br></p>

<p>Applications 4-(4,6-Bis(4-((2-ethylhexyloxy)carbonyl)phenylamino)-1,3,5-triazin-2-ylamino)benzoic Acid is an impurity in the synthesis of Ethylhexyl Triazone (E918810), used in sunscreen formulations as a UV filter to block out harmful ultraviolet light.<br>References Potard, G. et al.: Int. J. Pharm., 189, 249 (1999); Couteau, C. et al.: J. Pharm. Biomed. Anal., 44, 270 (2007);<br></p>

<p>Applications Pentafluorobenzoic acid (cas# 602-94-8) is a useful research chemical.<br></p>

<p>Applications (2E)-3-Phenyl-2-propenoic Acid is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines. Also used in the N-methylation of amides and O-methylation of carboxylic acids.<br>References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);<br></p>

<p>Applications 3,3-Dimethylbutyric Acid is used in the synthesis of imidazo[4,5-c]pyridine derivatives as anitmicrobial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jose. G., et. al.: Eur. J. Med. Chem., 77, 288 (2014)<br></p>

<p>Applications Antioxidant.<br>References Arnous, A., et al.: J. Agr. Food Chem., 49, 5736 (2001), Guendez, R., et al.: Food Chem., 89, 1 (2005), Proestos, C., et al.: Food Control,16, 319 (2005)<br></p>

<p>Applications 2-butoxyacetic acid (cas# 2516-93-0) is a useful research chemical.<br></p>

<p>Applications (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-yl Acetate is an intermediate in the synthesis of JHSB3 (J211030). JHSB3 is an acyclic sesquiterpenoid that regulates many aspects of insect physiology. Juvenile Hormone regulate development, reproduction, diapause, and polyphenisms.<br>References Kotaki, T., et al.: Org. Let., 11, 5234 (2009); Riddiford, L.: Adv. Insect Physiol., 24, 213 (1994); Wyatt, G., Davey, K.: Adv. Insect Physiol., 26, 1 (1996); Nijhout, H.: Insect Hormones (Princeton Univ. Press, Princeton) (1994)<br></p>

<p>Applications 2-Amino-4-(methylsulfonyl)benzoic Acid is a reagent used in the synthesis of anthranilic diamides containing fluorinated groups as potential ryanodine receptors activators.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, C. et al.: Chem. Lett., 28, 1248 (2017);<br></p>

<p>Applications 5-(3-hydroxyphenyl)pentanoic acid (cas# 31129-95-0) is a useful research chemical.<br></p>

<p>Applications Intermediate in the preparation of Camostat metabolites.<br>References Bodor, N., et al.: Pharm. Res., 3, 120 (1984), Han, L., et al.: Biochem., 46, 1432 (2007),<br></p>

<p>Applications A naturally occurring chelation agent.<br>References Boonme, P., et al.: J. Biomed. Nanotechnol., 5, 373 (2009), Noh, J., et al.: Bioorg. Med. Chem., Lett., 19, 5586 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>

<p>Applications 2-Ethylbutyric Acid is used in biological studies as a possible descriptor for toxicity prediction through electrophilicity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Roy, D.R., et al.: Bioorg. Med. Chem., 13, 3405 (2005); Parthasarathi, R., et al.: J. Phys. Chem. A., 107, 10346 (2003)<br></p>

<p>Applications A benzoic acid derivative used in photolysis reactions and biomaterial studies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wetzels, G.M. et al.: Biomaterials., 20, 1879 (1999); Mao, C. et al.: Adv. Coll. Int. Sci., 110, 5 (2004);<br></p>

<p>Applications Ethyl Nitroacetate is an ester of nitrocarboxylic acid used as an intermediate in the preparation of unsubstituted amino acids.<br>References Sidorin, G.I.: Gig. Aspe. Okhr. Zdor. Nasel., 144 (1977);<br></p>

<p>Applications DL-2,4-Diaminobutyric Acid Dihydrochloride (cas# 65427-54-5) is a useful research chemical.<br></p>

<p>Applications D-Lactic Acid occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity.<br>References He, W. et al.: Comp. Biochem. Phys. Part A: Mol. Int. Phys., 166, 308 (2013)<br></p>

<p>Applications 2-(4-Hydroxycyclohexyl)acetic acid (cas# 99799-09-4) is a useful research chemical.<br></p>

<p>Applications DL-2-aminobutyric acid<br></p>

<p>Applications 2-[(phenylsulfanyl)methyl]benzenecarboxylic acid (cas# 1699-03-2) is a useful research chemical.<br></p>

<p>Applications 2-Cyclopentyl-2-hydroxy-2-phenylacetic Acid is an impurity of Glycopyrrolate (G657000), a novel pharmaceutical compound based on PDE IV inhibitors; used in the treatment of respiratory complaints. It is used in the synthesis of muscarinic M3 receptor antagonists.<br>References Gomez, et al.: Br. J. Anaesth., 74, 549 (1995); Kumar, N. et al.: Bioorg. Med. Chem. Lett., 17, 5256 (2007);<br></p>

<p>Applications Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.<br>References Day, J. et al.: Chem. A Eur. J., 16, 2758 (2010); Sechi, M. et al.: Bioorg. Med. Chem., 17, 2925 (2009);<br></p>

<p>Applications 2-(2-ethoxyethoxy)acetic acid (cas# 7743-94-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Mercaptopropionic Acid (cas# 107-96-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 17-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid is an intermediate used to prepare (11β,​17α)​-17-​[(Ethoxycarbonyl)​oxy]​-​11-​hydroxy-​3-​oxo-​androsta-​1,​4-​diene-​17-​carboxylic acid (E890570) which is a derivative of Loteprednol Etabonate (L471400), an ophthalmic corticosteroid.<br>References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)<br></p>

<p>Applications 3-O-Ethyl-L-ascorbic Acid could be a useful stabilizing agent for a para-​hydroxyacetophenone solution.<br>References Zhang, H., et al.: Faming Zhuanli Shenqing (2020), CN 111937874 A<br></p>

<p>Applications tert-butyl N-[3-(chlorosulfonyl)propyl]carbamate (cas# 1196153-59-9) is a useful research chemical.<br></p>

<p>Applications 5-(3,4-dihydroxyphenyl)pentanoic Acid (cas# 31129-94-9) is a useful research chemical.<br></p>

<p>Applications 4-(ETHOXYCARBONYL)BENZOIC ACID (cas# 713-57-5) is a useful research chemical.<br></p>

<p>Applications PERFLUORO-3,6-DIOXAHEPTANOIC ACID (cas# 151772-58-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications An effective agent for increasing nicotinamide adenine dinucleotide (NAD) concentrations in mammalian cells.<br>References Yang, T. et al.: J. Med. Chem., 50, 6458 (2007);<br></p>

<p>Applications Methyl 5-chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate (cas# 144172-24-7) is a useful research chemical. It is an intermediate in the synthesis of IN-KG 433 (I627995). IN-KG 433 is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.<br>References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);<br></p>

<p>Applications Ethacrynic Acid Epoxide is an intermediate in the synthesis of Ethacrynic Acid (E676000), a diuretic used to treat high blood pressure and swelling caused by congestive heart failure, liver failure and kidney failure.<br>References Beyer, et al.: J. Pharmacol. Exp. Ther., 147, 1 (1965), Kim., et al.: Am. J. Cardiol., 27, 407 (1971), Williamson, H.E., et al.: J. Clin. Pharmacol., 17, 663 (1977),<br></p>

<p>Applications Ethyl hydrazinoacetate, HCl<br></p>

<p>Applications 2-(Hydroxyimino)-3-phenylpropanoic acid (cas# 3682-17-5) is a useful research chemical.<br></p>

<p>Applications 2-(Acetylamino)-3-(phenylthio)propanoic acid is a useful chemical in research.<br></p>

<p>Applications methyl 5-(hydroxymethyl)furan-2-carboxylate (cas# 36802-01-4) is a useful research chemical.<br></p>

<p>Applications ACETOACETIC ACID ISOAMYL ESTER (cas# 2308-18-1) is a useful research chemical.<br></p>

<p>Applications Veratric Acid is a derivative of Protocatechuic Acid. Veratric Acid is a reagent used in the production of antimicrobial agents, antifeedants, and a variety of other biologically active compounds.<br>References Alissandrakis, E., et al.: Eur. Food Res. Technol., 229, 365 (2009), Spaccini, R., et al.: Soil Biol. Biochem., 41, 1164 (2009), Narasimhan, B., et al.: Eur. J. Med. Chem., 44, 689 (2009), Pereira, L., et al.: J. Biotechnol., 139, 68 (2009),<br></p>

<p>Applications Tert-butyl Acetate is a common solvent used in the production of various industrial cleansers, thinners and adhesives and is also known as a VOC.Environmental contaminants; Food contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mackay, D., et al.: SAR. QSAR. Enviro. Res., 23, 205 (2012); Yang, Y.S., et al.: Toxicol. Res., 26, 293 (2010);<br></p>

<p>Applications Dithiocarbamate complexes serve as hosts for the specific binding of various metal cations.<br>References Bourson, J., et al.: J. Phys. Chem., 97, 4552 (1993), Lai, S., et al.: Inorg. Chem., 38, 4262 (1999),<br></p>

<p>Applications N-Undecylbenzenesulfonic Acid is an anionic surfactant.<br>References Mottaleb, M. A.: Anal. Sci., 15, 1137 (1999), Kolb, M., et al.: LaborPraxis, 22, 56 (1998); Ferrer D., et al.: Tenside, Surfact., Det., 34, 278 (1997)<br></p>

<p>Applications 2,2-Diphenylpentanoic Acid (cas# 841-32-7) is a compound useful in organic synthesis.<br></p>

<p>Applications Z-2-Fluoro-3-(3-pyridyl)acrylic Acid (cas# 359435-42-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-(Aminocarbonyl)-3-cyclohexene-1-carboxylic Acid is a useful building block for organic synthesis.<br></p>

<p>Applications 2-(7-Amino-2-oxo-2H-chromen-4-yl)acetic acid (cas# 85157-21-7) is a useful research chemical.<br></p>

<p>Stability Volatile<br>Applications Methyl Acetate is used as an organic chemical solvent for a multitude of organic processes. Also used in the production of biodiesel.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, Y. et al.: J. mol. Cat., 32, 241 (2005); Ogino, H. et al.: J. Biosci. Bioeng., 89, 451 (2000);<br></p>

<p>Applications 5-Chloronicotinic Acid is used as reagent/reactant luminescence and hydrothermal preparation of cobalt/cadmium/lead chloronicotinate phenanthroline MOF.<br>References Gao, Z.Q., et al.: J. Solid State Chem., 241, 121-130 (2016)<br></p>

<p>Applications 4-Sulfamoylbenzoic Acid is used as a reagent in the synthesis of carbonic anhydrase inhibitors anticonvulsant agents.<br>References Singh, S. et al.: J. Enz. Inhib. Med. Chem., 31, 417 (2016);<br></p>

<p>Stability Hygroscopic<br>Applications 3-Carboxamidobenzoic acid<br></p>

<p>Applications 11-MERCAPTOUNDECANOIC ACID (cas# 71310-21-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Hydroxytetradecanoic Acid is used in the preparation of liposomes coated with N-acylated molecular-weight. Also used in the synthesis of pseudomycin side-chain analogs. Also used in the study of Lipid A, a major constituent of the lipopolysaccharides, which are responsible for the toxicity of gram negative bacteria.<br>References Naberezhnykh, G. et al.: Chem. Nat. Comp., 46, 852 (2011); Chen, S. et al.: Bioorg. Med. Chem. Lett., 10, 2107 (2000); Carillo, S. et al.: Marine Drugs., 11, 184 (2013);<br></p>

<p>Applications Formic Acid-d is labelled Formic Acid (F692900). Formic Acid (F692900) is used as a potential energy source in the preparation of fuel cells. Also used in chemical synthesis of various anti-inflammatory and anti-microbial agents.<br>References Yu, X. et al.: J. Power Source., 182, 124 (2008); Bekhit, A. et al.: Bioorg. Med. Chem., 12, 1935 (2004);<br></p>

<p>Applications Succinic Acid was identified in essential oil from Saxifraga stolonifera and has antibacterial activity.<br>References Zhang, Z.: Xibei Nongye Xuebao, 25, 1536 (2016)<br></p>

<p>Stability Hygroscopic<br>Applications N-​(4-​Amino-​5-​oxoheptyl)​guanidine is a biosynthetic intermediate in the study of saxitoxin gene cluster in cyanobacteria.<br>References Kellmann, R., et al.: Appl. Environ. Microbiol., 74, 4044 (2008)<br></p>

<p>Applications 2-hydroxyhexanoic acid (cas# 6064-63-7) is a useful research chemical.<br></p>

<p>Applications 5,6-dibromonicotinic acid (cas# 29241-64-3) is a useful research chemical.<br></p>

<p>2-Naphthoxyacetic acid is an endogenous metabolite that is an inhibitor of firefly luciferase (Potency=40 μm).</p>

<p>Impurity Methyl Salicylate USP Related Compound A<br>Applications 4-Hydroxy-isophthalic Acid Dimethyl Ester (cas# 5985-24-0) is a compound useful in organic synthesis.<br></p>

<p>Applications n-Nonanoic Acid is commonly used in conjunction with glyphosate, a non-selective herbicide, for a quick burn-down effect in the control of weeds in turfgrass. It is also used in the preparation of plasticizers and lacquers.<br>References Pline, W., et al.: Weed Technol., 14, 667 (2000); Frade, J., et al.: Anal. Bioanal. Chem., 395, 2167 (2009);<br></p>

<p>Applications 4-Dodecylbenzenesulfonic acid<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Nicotinic Acid 2-Diethylamino-Ethyl Ester (cas# 3099-52-3) is a useful research chemical.<br></p>

<p>Applications 3,4,9,10-Perylenetetracarboxylic diimide (cas# 81-33-4) is a useful research chemical.<br></p>

<p>Applications 3,4-Secocholest-5-ene-3,4-dioic Acid Dimethyl Ester is an intermediate used in the synthesis of 3,4-Seco-solanidine-3,4-dioic Acid (S682410), which is a derivative of Solanidine (S682410).<br></p>

<p>Applications 3,5-Di-tert-butyl-4-hydroxybenzoic acid<br></p>

<p>Applications 4,4'-Dithiobisbenzoic Acid, Technical Grade (cas# 1155-51-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,4-dibutyl benzene-1,4-dicarboxylate (cas# 1962-75-0) is a useful research chemical.<br></p>

<p>Applications DL-3-phenyllactic acid had been identified as a urinary food intake biomarker for milk, cheese and soy-based drinks.<br>References Munger, L.H.; et al.: J. Proteome Res., 16, 3321 (2017)<br></p>

<p>Applications 2-Azidobenzoic Acid (cas# 31162-13-7) is a useful research chemical.<br></p>

<p>Applications Repaglinide intermediate.<br>References Wolfenbuttel, B., et al.: Eur. J. Clin. Pharmacol., 45, 113 (1993), Grell, W., et al.: J. Med. Chem., 41, 5219 (1998), Anon., et al.: Drugs Future, 24, 815 (1999),<br></p>

<p>Applications 2-Ethylhexanoic Acid is used in biological studies as flavor precursor extraction from different grape varieties and its effect on wine aroma during alcohol fermentation<br>References Loscos, N., et al.: J. Agric. Food Chem., 55, 6674 (2007)<br></p>

<p>Applications (Z)-11-Tetradecenyl Acetate is a sex pheremone component that can be found in various insect specie, such as O. nubilalis and Asian and European corn borers.<br>References Leary, G.P., et al.: Proc. Natl. Acad. Sci. U.S.A., 109, 14081 (2012);<br></p>

<p>Applications butyl carbamate (cas# 592-35-8) is a useful research chemical.<br></p>

<p>Applications trans-3-(2-Chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid is a reagent used in the synthesis of indanyl insecticides.<br></p>

<p>Applications Phthalic Acid Bis(3,7-dimethyloctyl) Ester is a diester derivative of Phthalic Acid (P384480) and can be used as a plasticizer for PVC-type compositions.<br>References Takeuchi, H., et al. Jpn. Kokai Tokkyo Koho. JP 2001002829 A 20010109. Jan 9, 2001<br></p>

<p>Applications 3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Ranu, B. et al.: J. Org. Chem. 65, 6270 (2000); Lu, J. et al.: Tetrahedron Lett., 41, 9075 (2000); Lu, J. et al.: Synlett., 1, 63 (2000);<br></p>

<p>Applications Hydrazine derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Ethyl Cyano(hydroxyimino)acetate is used in peptide synthesis and has shown to suppress racemiztion, has high coupling efficiency in both solution and solid phase synthesis and is a non-explosive alternative to 1-hydroxybenzotriazole (HOBt) and 1-hydroxy-7-azabenzotriazole (HOAt).<br>References Khattab, S.N.: Bull. Chem. Soc. Jpn., 83, 1374 (2010)<br></p>

<p>Applications 4-(Methoxymethyl)benzoic acid<br></p>