Carboxylic Acids

<p>Please enquire for more information about 3-(Prop-2-enylamino)-5-methyl-2,4-thiazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-(Dimethylamino)phenyl)-1,3-thiazolidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(N-cyclopropylcarbamoyl)cyclohexanecarboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((4-methoxyphenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about methyl 2-(4,5-dimethoxy-2-(((4-(trifluoromethylthio)phenyl)amino)sulfonyl)phenyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-(Pyrimidin-2-ylamino)-3,5-thiazolyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(2,6,6-Trimethyl-4-oxo-5,6,7-trihydroindolyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 2-(2-(indolin-1-ylsulfonyl)-4,5-dimethoxyphenyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 2-(4-(2-(trifluoromethyl)phenylamino)-3,5-thiazolyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(2,6,6-Trimethyl-4-oxo-5,6,7-trihydroindolyl)propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((3-Bromophenyl)amino)-1,3-thiazole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-((3-bromophenyl)amino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-((1-oxo-2-phenylinden-3-yl)amino)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((4-Ethoxyphenyl)amino)-4-methyl-1,3-thiazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(2-((Benzo[d]1,3-dioxolan-5-ylamino)sulfonyl)-4,5-dimethoxyphenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (3-Chloro-phenyl)-acetic acid hydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((3-chlorophenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((4-Bromophenyl)amino)-1,3-thiazole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ethyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)benzenecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(N-(2-(3,4-dimethoxyphenyl)ethyl)carbamoyl)pyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((4-(trifluoromethoxy)phenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about methyl 2-(4,5-dimethoxy-2-(((4-(trifluoromethyl)phenyl)amino)sulfonyl)phenyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ethyl 3-((4-fluorophenyl)amino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((3,5-Dichlorophenyl)amino)-1,3-thiazole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The compound trans-3-(4-methylbenzoyl)acrylic acid is a potent and selective inhibitor of serine/threonine protein kinase. It has been shown to inhibit the proliferation of eosinophils in vitro, as well as to suppress the release of leukotrienes from human mast cells. The mechanism of action is by inhibiting phosphatidylcholine-specific phospholipase C, which leads to the inhibition of protein kinase C. This inhibition prevents the phosphorylation of various proteins, including cytoskeletal proteins that are required for cell division.</p>

<p>Please enquire for more information about 2-(4-Isopropylbenzenesulfonyl)propionic acid hydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about methyl 2-(3-(3-nitrophenyl)prop-2-enoylamino)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2,4-Dibromophenoxy)acetic acid is a chemical compound with an empirical formula of C7H4Br2O4. The crystalline form of this compound has been analysed and optimised for surface analysis and crystallography. This molecule is also a model compound for coordination chemistry studies. Experimental data has been collected from bioassays that demonstrate the ligand's ability to bind to metal ions. X-ray crystallography has shown the molecular structure of (2,4-dibromophenoxy)acetic acid as a ligand in coordination with a metal ion in which the bromine atom is bonded to two oxygen atoms on the metal ion, forming a trigonal bipyramidal geometry.</p>

<p>Please enquire for more information about methyl 2-(4,5-dimethoxy-2-(thiomorpholin-4-ylsulfonyl)phenyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((2-Fluorophenyl)amino)-1,3-thiazole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(3-bromo-4,5-dimethoxyphenyl)acrylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((2,4-Dichlorophenyl)amino)-4-methyl-1,3-thiazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(N-(5-Methylisoxazol-3-yl)carbamoyl)cyclohexanecarboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((3-(Trifluoromethoxy)phenyl)amino)-1,3-thiazole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dynorphin A (1-10) acetate salt H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH acetate salt is a dynorphin analog with analgesic activity. It has been shown to have a beneficial effect in the tail flick test and immobilization tests. Dynorphin A (1-10) acetate salt H-Tyr-Gly-Gly-Phe-Leu-Arg can be used as an analgesic for pain relief. This compound also has antiinflammatory effects, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Please enquire for more information about ethyl 2-(4-(4-methylphenylamino)-3,5-thiazolyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-piperidinecarboxylic acid (3CFP) is a phenoxy carboxamide that is an anticonvulsant. 3CFP has been shown to be effective in animal models of seizure and has a potency that exceeds that of phenobarbital. It also has potent anticonvulsant activity against seizures induced by pentylenetetrazole and electroshock. 3CFP binds to the GABA receptor, which is important for the regulation of neuronal excitability and is the target for many types of antiepileptic drugs. The chlorine atom in 3CFP may contribute to its pharmacological properties because it can form a covalent bond with amino acids like cysteine, which are important for protein synthesis.</p>

<p>Please enquire for more information about Ethyl 2-(4-(4-bromophenylamino)-3,5-thiazolyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-(3-pyridylamino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-((4-Ethyl-5-oxo-3-thioxo-2,4-thiazolidinylidene)methyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((3-Bromophenyl)amino)-4-methyl-1,3-thiazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-(2-pyridylamino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(3,4-Dimethoxyphenyl)-1,3-thiazolidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4,5-Dimethoxy-2-(thiomorpholin-4-ylsulfonyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(3-Carboxyprop-2-enoylamino)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Applications (+/-)-Nipecotic Acid (cas# 498-95-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties . Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chen, Y. et al.: J. Med. Chem., 56, 4671 (2013); J. Med. Chem., 55, 10610 (2012);<br></p>

<p>Applications [2-(aminocarbonyl)phenoxy]acetic acid (cas# 25395-22-6) is a useful research chemical.<br></p>

<p>Applications Ethyl 2-(2,6-Dichlorophenyl)acetate (cas# 90793-64-9) is a useful research chemical.<br></p>

<p>Applications Used in the synthesis of anti-tumor compounds comprising of hydroxyisovalerylshikonin analogs. Furthermore, the compound is a reagent in the synthesis of class II c-Met inhibitors, in the treatment of c-Met dependant tumors.<br>References Rao, Z. et al.: Eur. J. Med. Chem., 46, 3934 (2011); Liu, L. et al.: J. Med. Chem., 55, 1868 (2012);<br></p>

<p>Applications 2,5-Dimethylthiophene-3-boronic acid<br></p>

<p>Applications Pentachlorophenyl Cyanoacetate is an intermediate used in the synthesis of Cefacetrile (C231500), which is a cephalosporin antibiotic. Antibacterial.<br>References Dajan, A., et al.: Vet. Microbiol., 35, 213 (1993), Becker, M., et al.: Anal. Chim. Acta, 520, 19 (2004), El-Shaboury, S., et al.: J. Pharm. Biomed. Anal., 45, 1 (2007),<br></p>

<p>Applications 2-Carboxyfuran-5-boronic acid, pinacol ester<br></p>

<p>Stability Air Sensitive<br>Applications Ethyl 2-Mercapto-1-cyclohexenecarboxylate is a reagent used in the synthesis of anti-inflammatory compounds,<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lloret, G. et al.: J. Phys. Org. Chem., 22, 1188 (2009);<br></p>

<p>Applications Dibenzo[b,d]furan-2-sulfonic acid (cas# 83863-63-2) is a useful research chemical.<br></p>

<p>Applications 2-Acetylphenylboronic Acid is a reactant used in the synthesis of potent, selective phenylimidazole-based tissue factor/factor VIIa (FVIIa) inhibitors.<br>References Glunz, P.W., et. al.: Bioorg. Med. Chem. Lett., 25, 21699 (2015)<br></p>

<p>Applications tert-Butyl N-Tosyloxycarbamate is a sulfhydroxylamine that, when used in combination with Lithium, functions as an efficient electrophile in the amination of chiral amide cuprate compounds. tert-Butyl N-Tosyloxycarbamate is also used as a reagent to synthesize N-Boc protected primary amines (e.g. N-Boc-ethylenediamine [B655000]).<br>References Chiba, S. &amp; Narasaka, K.: Amin. Grou. Chem: Synth. Life Sci., No vol. given (2008); Gallou, I. &amp; Senanayake, C.: Chem. Rev.: 106, 2843 (2006); Genet, J., et al.: Tetrahedron Lett., 32, 2359 (1991); Zheng, N., et al.: ChemInform, 28, No pp. given (1997)<br></p>

<p>Applications tert-Butyl N-(Benzyloxy)carbamate has been used in the synthesis of Deferoxamine Mesylate (D228980), an iron chelating agent used in therapy for patients with sickle cell diseases and iron overload. Studies suggest that it can exert potential antioxidant neuroprotective effects in stroke patients<br>References Bergeron RJ, et al. 1992. J Med Chem. Dec 11;35(25):4739-44Inati A, et al. 2010. Am J Hematol. Oct;85(10):782-6 Selim M, et al. 2010. Transl Stroke Res. Mar;1(1):35-9<br></p>

<p>Applications Diethyl Iminodiacetate<br></p>

<p>Applications 3-{4-[(furan-2-ylmethyl)sulfamoyl]phenyl}prop-2-enoic acid (cas# 391229-93-9) is a useful research chemical.<br></p>

<p>Applications 2-Aminobenzenesulphonic acid (cas# 88-21-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2,2,5-Trimethyl-1,3-dioxane-5-carboxylic Acid Ethenyl Ester (cas# 865860-80-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(Diphenylphosphino)benzoic Acid is used in small molecule control of protein function through staudinger reduction.<br>References Luo, J., et al.: Nat. Chem., 8, 1027 (2016)<br></p>

<p>Applications 3-Isopropylbenzoic acid<br></p>

<p>Applications o-Bromophenoxyacetic acid<br></p>

<p>Applications tert-Butyl 3-Cyanomorpholine-4-carboxylate is used as a reactant for the synthesis of HIV integrase inhibitors.<br>References Gardelli, C., et. al.: J. Med. Chem., 50, 4953 (2007); Pace, P., et. al.: J. Med. Chem., 50, 2225 (2007); Summa, V., et. al.: J. Med. Chem., 49, 6646 (2006)<br></p>

<p>Applications (S)-2-[(Methylsulfonyl)oxy]propanoic Acid is used as a treatment to significantly improve the selectivity of optically active agent (S)-2-(4-Isobutylphenyl)propionic Acid during its synthesis.<br>References Garot, C., et al.: Bull. Soc. Chim. Belg., 105, 755-757 (1996)<br></p>

<p>Applications Used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.<br>References Leeman, M. et al.: Angew. Chem. Int. Ed., 47, 1287 (2008); Eur. J. Med. Chem., 45, 3564 (2010);<br></p>

<p>Applications 3-Amino-3-(3-(p-tolyloxy)phenyl)propanoic Acid is a useful chemical reagent.<br></p>

<p>Applications 6-Bromo-2-chloronicotinic acid<br></p>

<p>Applications 2,4-Diaminobenzenesulfonic acid (cas# 88-63-1) is a useful reagent for improving the chlorine resistance and water permeability of polyamide (PA) membrane in water treatment.<br>References Meng, Q. W., et al.: ACS Applied Mat., 12, 35393 (2020)<br></p>

<p>Applications (E)-2-Thiopheneacrylic Acid is used in the synthesis of anti-HIV HEPT analogs. Also used in the synthesis of benzimidazole and caffeine (C080100) analogs as inhibitors of monoamine oxidase B.<br>References Pontikis, R. et al.: J. Med. Chem., 40, 1845 (1997); van den Berg, D. et al.: Bioorg. Med. Chem., 15, 1692 (2007);<br></p>

<p>Applications 2-(Methoxyimino)-3-oxo-butanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of Cefotaxime Bromoacetyl Analogue (C242940), which is an impurity of Cefotaxime (C242950), a broad spectrum third generation cephalosporin antibiotic.<br>References Wise, R., et al.: Antimicrob. Agents Chemother., 14, 807 (1978), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 11, 139 (1982),<br></p>

<p>Stability Moisture Sensitive<br>Applications Methyl (chlorosulfonyl)acetate<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 4-(2-Aminophenyl)-4-oxo-2-butenoic Acid is a novel human lens metabolite from normal and cataractous human lenses. A UV filter.<br>References Mizdrak, J., et al.: Tetrahedron, 63, 4990 (2007); Taylor, L. M., et al.: Exp. Eye Res., 75, 165 (2002)<br></p>

<p>Applications 5-carbamoylpentanoic acid (cas# 334-25-8) is a useful research chemical.<br></p>

<p>Applications Benzothiophene-5-boronic acid<br></p>

<p>Impurity Fluorouracil EP Impurity B; Fluorouracil USP Related Compound B<br>Applications A 5-hydroxy derivative of the nucleobase Uracil (U801000) and an isomer of Barbituric Acid (B118650). Studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been used as oxidative DNA damage biomarker in tissue engineered skin. Fluorouracil EP Impurity B. Fluorouracil USP Related Compound B<br>References Varatharasa T. et al.: Chem. Comm., 3, 400 (2005); Jaruga, P. et al.: Nucleic Acid Res., 24, 1389 (1996); Rodriguez, H. et al.: Adv. Exp. Med. Biol., 534, 129 (2003);<br></p>

<p>Applications (2S)-2-acetamido-5-(diaminomethylideneamino)pentanoic Acid (cas# 155-84-0) is a useful research chemical.<br></p>

<p>Applications tert-Butyl 2-(3-Aminophenyl)acetate can be used as anti-heparanase to treat diseases and disorders associated with heparanase activity.<br>References Giannini, G., et.al.: PCT Int. Appl., 103, (2018);<br></p>

<p>Applications A useful synthetic intermediate.<br>References Li, A., et al.: J. Med. Chem., 42, 706 (1999), Low, E., et al.: Bioorg. Med. Chem. Lett., 19, 196 (2009),<br></p>