Carboxylic Acids

<p>Stability Moisture Sensitive<br>Applications Tripropyl phosphate is an organophosphorus flame retardant and plasticizer.<br>References Bacaloni, A., et al.: Environ. Sci. Technol., 42, 1898 (2008)<br></p>

<p>Stability Store in Freezer<br>Applications A useful synthetic intermediate for the preparation of novel antiinflammatory agents.<br></p>

<p>Applications 8,13(15)-Abietadienoic Acid is a derivative of Methyl Abietate (M271910) and has cytotoxic, antimycotic, and antiviral activites.<br>References Gonzalez, Miguel A., et al.: Eur. J. Med. Chem., 44(6), 2468-2472 (2009); Agudelo-Gomez, Lee Solbay., et al.: Pharmacologyonline, 1, 36-42 (2012)<br></p>

<p>Applications Amino(3-​chlorophenyl)​acetic Acid functions as intermediate useful in the preparation of synthetic penicillins, also used in the structure-activity relationship examination of several drugs containing the benzyl moiety, their roles in biochemical and pharmacological processes.<br>References Hansch, C., et al.: J. Med. Chem., 13, 957 (1970); Holdrege, C. T., et al.: Can. (1975), CA 966853 A2 19750429;<br></p>

<p>Applications Chromane-2-carboxylic Acid is used in the synthesis of 4-quinazolinones as Rho kinase inhibitors for application towards glaucoma, hypertension and spinal cord injuries. It is also used in the preparation of chromanyl-benzamidazoles as anti-bacterial compounds.<br>References Fang, X. et al.: Bioorg. Med. Chem. Lett., 21, 1844 (2011); Raut, C. et al.: J. Hetero. Chem., 47, 582 (2010);<br></p>

<p>Applications 3-Phosphonobenzoic Acid (cas# 14899-31-1) is a useful research chemical.<br></p>

<p>Applications 2`,3`-Dideoxy-5`-guanylic Acid is a component used in pyrophosphorolysis activated polymerization applied to allele-specific amplification and nucleic acid sequence detection.<br>References Liu, Q.; et al.: PCT Int. Appl. 70 pp. Patent 2001 CODEN:PIXXD2<br></p>

<p>Stability Light Sensitive<br>Applications 3-(3-Hydroxyphenyl)acrylic acid (cas# 588-30-7) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Propylphosphonic Acid, is an alkylphosphonic acid, and a building block used in the synthesis of chemical compounds such as extremely toxic nerve agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deepak P. et al.: J. of Cherom. A. 1141(2), 151-157 (2007);<br></p>

<p>Applications Triethyl Orthoacetate is used in the preparation of potent and selective human A3 adenosine receptor antagonists. Also used in the preparation of 1,3,4-oxadiazoles for potential antimicrobial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Squarcialupi, L. et al.: J. Med. Chem., 56, 2256 (2013); Vodela, S. et al.: Chin. Chem. Lett., 24, 625 (2013);<br></p>

<p>Applications Phenethyl Carbamate is an impurity in the synthesis of Felbamate (F231000), an antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>

<p>Applications Substituted cinnamic and dihydrocinnamic acids show anti-inflammatory and analgesic activity, with cinnamic acids being more biologically active.<br>References Runwal, L. et al.: Eastern Pharmacist 38, 141 (1995)<br></p>

<p>Applications [2-(aminocarbonyl)phenoxy]acetic acid (cas# 25395-22-6) is a useful research chemical.<br></p>

<p>Applications 2,4,5-TRIMETHOXYBENZOIC ACID (cas# 490-64-2) is a useful research chemical.<br></p>

<p>Applications 2-(5-formylfuran-2-yl)benzoic Acid (cas# 88460-72-4) is a useful research chemical.<br></p>

<p>Applications 2,6-Dimethylphenylboronic acid<br></p>

<p>Applications 5-Hydroxy-3-phenylbenzoic Acid can be used in biological study of preparation and identification of hydroxybenzoic acids as lactate receptor agonists and antilipolytics. It can also be used in discovery of new series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.<br>References Duffy, B. C., et al.: Bioorg Med Chem Lett, 25, 2818 (2015), Dvorak, C. A., et al.: ACS Med Chem Lett, 3, 637 (2012)<br></p>

<p>Applications 2-amino-6-hydroxybenzoic acid (cas# 567-62-4) is a useful research chemical.<br></p>

<p>Applications 2-Isopropoxy-2-phenylacetic acid<br></p>

<p>Applications 4-tert-Butoxyphenylboronic Acid is a compound used in the preparation of nitrophenylphenol via cross-coupling reaction of nitrohalobenzenes with phenylboronic acids and deprotection.<br>References Kumamoto, N., et al.: Preparation of nitrophenylphenol, JP 2001055360 (2001);<br></p>

<p>Applications Azidoacetic acid NHS ester (cas# 824426-32-6) is a useful research chemical.<br></p>

<p>Applications tert-Butyl (5-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate is used as a reactant in the synthesis of BRAF-kinase inhibitors.<br>References Repik, Alexey E., et al.: PCT Int. Appl., WO 2017146604 A1 20170831 (2017)<br></p>

<p>Applications 2-Aminomethylphenylacetic Acid is an intermediate of Ceforanide (C242930), a cephalosporin based antibiotic used in the sterilization in various medical procedures.<br>References Zhao, Y., et. al.: Res. Chem. Int. 40, 1637 (2014); Sifakis, S. et al.: Arch. Gyne. Obst., 272, 201 (2005); DiPiro, J. et al.: Antimicrob. Agents Chemother., 27, 287 (1985)<br></p>

<p>Applications Methyl Dimethoxyacetate is used as a reagent in the synthesis of benzimidazole derivatives for use as respiratory syncytial virus inhibitors.<br>References Cooymans, Ludwig Paul; D., et al. PCT Int. Appl. WO 2012080446 A1 20120621. Jun 21, 2012<br></p>

<p>Applications Synthesis and receptor binding of 5-(amino[3H]2methyl)-3-isothiazolol ([3H]thiomuscimol), a specific GABAA agonist photoaffinity label.<br>References Frolund, B., et al.: J. Labelled Compounds Radiopharm., 36, 877 (1995),<br></p>

<p>Applications (1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate Oxalate has been used as a reactant for the preparation of oxadiazole compounds containing cyclohexanediamine moiety.<br></p>

<p>Applications trans-1,2-Cyclohexanedicarboxylic Acid is used as a reagent in the synthesis of enantiopure (α-cyanoalkyl)(tetrahydropyrido[4,3-b]indolecarbonyl)cyclohexanecarboxamides and its analogs as selective cathepsin K inhibitors for the treatment of osteoarthritis. Also used as a reagent in the synthesis of novel cyclopentanedicarboxamide sodium channel blockers as a potential treatment for chronic pain.<br>References Dossetter, A.G., et al.: J. Med. Chem., 55, 6363 (2012); Shao, P.P., et al.: Bioorg. Med. Chem. Lett., 15, 1901 (2005)<br></p>

<p>Applications Benzyl Acetoacetic Amide (cas# 882-36-0) is a compound useful in organic synthesis.<br>References Sakaki, J., et al.: Chem. Pharm. Bull., 37, 2952 (1989),<br></p>

<p>Applications 2-Mercapto-succinic acid diethyl ester (cas# 23060-14-2) is a useful research chemical.<br></p>

<p>Applications 2-Phenylthio-5-propionylphenylacetic Acid is a useful synthetic intermediate in the synthesis of Zaltoprofen (Z146000); an inhibitor of Cox-1 and Cox-2. Zaltoprofen preferentially inhibits Cox-2.<br>References Chen, W., et al.: Faming Zhuanli Shenqing. CN 1986528 A 20070627. Jun 27, 2007; Yamamoto, M., et al.: Chirality, 2, 280 (1990); Inoue, M., et al.: J Pharmacol. Exp. Ther., 293, 662 (2000)<br></p>

<p>Applications TERT-BUTYL N-(DIAMINOMETHYLIDENE)CARBAMATE (cas# 219511-71-4) is a useful research chemical.<br></p>

<p>Applications 1,1,2-Ethanetricarboxylic Acid 1,1,2-Triethyl Ester is a useful synthetic intermediate. It can be used to prepare Isobutylsuccinic Acid (I780660) which was used to synthesize succinimide derivatives as inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.<br>References Groutas, W., et al.: Bioorg. Med. Chem., 3, 375 (1995);<br></p>

<p>Stability Air Sensitive<br>Applications methyl 2-(2-formylphenyl)acetate (cas# 63969-83-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 4-Benzyl-morpholine-2-carboxylic is used in the synthesis of novel morpholine conjugated benzophenone analogs and evaluation of antagonistic role against neoplastic development.<br>References Al-Ghorbani, Mohammed. et al., Bioorg. Chem. 71, 55-66(2017);<br></p>

<p>Applications 5-Formylfuran-2-boronic Acid Pinacol Ester could be useful for the diastereoselective synthesis of cyclic peptide macrocycles via Petasis borono-Mannich reaction<br>References Yamaguchi, A., et al.: Chem. Commun. (Cambridge, U. K.), 55, 10567 (2019)<br></p>

<p>Applications 2-Phenoxypropionic Acid is used in organic chemistry reduction reactions. Used in the synthesis of PPAR (peroxisome proliferator-activated receptor (PPAR) ligands.<br>References Brown, P. et al.: Synthesis., 7, 778 (1997);<br></p>

<p>Applications (2R)-4-(1,1-Dimethylethyl) Ester 2,4-Morpholinedicarboxylic Acid is used in the preparation of renin inhibitors.<br>References Yuan, J. et al.: Bioorg. Med. Chem. Lett., 21, 4836 (2011); Fish, P. et al.: Tetra. Lett., 50, 389 (2009);<br></p>

<p>Stability Temperature Sensitive<br>Applications 2-Oxocyclopentanecarboxylic Acid is a reactant that has been used in the synthesis of Piragliatin, a glucokinase activator.<br>References Sarabu, R., et. al.: J. Med. Chem., 55, 7021 (2012)<br></p>

<p>Applications 4-(2,3-Dihydro-1H-indol-1-yl)-4-oxobutanoic Acid (cas# 105105-00-8) could be useful in biological studies. It has been used to screen and target LsrK kinase inhibitors.<br>References Medarametla, P., et al.: ChemMedChem, 13, 2400 (2018)<br></p>

<p>Please enquire for more information about Methyl 2-amino-4,6-dichloropyridine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl 6-chloro-2-pyridinecarboxylate is a reactive, organic compound that belongs to the class of monomers. It is a white crystalline solid with a melting point of approximately 130 degrees Celsius. This chemical can be synthesized by reacting 2-chlorobenzothiazole with sodium carbonate in water at temperatures between 100 and 140 degrees Celsius. The reaction yields methyl 6-chloro-2-pyridinecarboxylate as well as chloride and picolinic acid as side products. This compound has been shown to have neurotoxic effects when administered to rats at high doses.</p>

<p>Please enquire for more information about 21-Hydroxy-pregna-1,4,16-triene-3,11,20-trione 21-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)isoxazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Hexynoic acid is a chemical compound that has been shown to have anticancer properties. The mechanism of action is not fully understood, but it may be due to its ability to inhibit an enzyme called irreversible acetylcholinesterase, which is involved in the production of several pro-inflammatory mediators. 5-Hexynoic acid has also been shown to inhibit the growth of prostate cancer cells and can be used as a therapeutic agent for prostate cancer. It is synthesized by plants and some microorganisms, although it is not found in humans. 5-Hexynoic acid can be produced from conjugates with glutamic acid or oxalyl chloride in an acidic environment.</p>

<p>Please enquire for more information about 2-Amino-3-(1.2-dihydro-2-oxoquinoline-4-yl)propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>This is a crystalline form of the pyrimidine derivative (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid. The compound has been shown to have antiplatelet properties and is currently being developed as an antithrombotic agent. In vitro studies have shown that ambrisentan inhibits platelet aggregation, thromboxane synthesis, and leukocyte adhesion. It also reduces the levels of serum cholesterol and triglycerides in patients with chronic heart failure. Ambrisentan has been studied in clinical trials for the treatment of pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).</p>

<p>A labelled form of the oxalacetic acid (FO12113).</p>

<p>Please enquire for more information about 2-Oxopyrrolidine-3-carboxylic acid ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,5-Difluoro-4-formylbenzoic acid is a sulfamic acid derivative that is used as a catalyst in the synthesis of aldehydes. The catalytic activity of 3,5-difluoro-4-formylbenzoic acid is due to its ability to be oxidized by air and light to give an active form. It also has other uses in the synthesis of dihydropyrans and regioselectivity studies.</p>

<p>Gibberellic acid methyl ester is a specialized plant growth regulator, which is synthetically derived from the naturally occurring gibberellins found in plants. These gibberellins are vital phytohormones that regulate various aspects of growth and development in higher plants. Gibberellic acid methyl ester functions by mimicking these natural gibberellins, interacting with plant cellular processes to stimulate and enhance growth. Its mode of action involves promoting cell elongation, division, and differentiation, thereby accelerating plant growth and influencing the lifecycle.</p>

<p>2-(Benzimidazolylthio) acetic acid is a ligand that can be used as an antihelminthic. It can also be used to produce luminescent substances, inorganic salts and heterocycles. 2-(Benzimidazolylthio) acetic acid reacts with nucleophiles by nucleophilic attack, cleaving the bond and releasing the atom or group. 2-(Benzimidazolylthio) acetic acid has been used to synthesize condensation products with irradiation. This chemical has been shown to have antimicrobial properties against bacteria and fungi.</p>

<p>3-Hydroxy-3-phenylpropanoic acid, or 3HPPA, is an intermediate in the synthesis of salicylic acid. It is also an endogenous metabolite found in urine samples and is a product of the metabolism of glucosinolates by hydrolysis. The hydroxyl group on 3HPPA reacts with a carbonyl group to form a Schiff base, which is then hydrolyzed by hydrochloric acid to form hippuric acid. The biosynthesis of 3HPPA occurs through the oxidation of fatty acids with the addition of a hydroxyl group from water.</p>

<p>Please enquire for more information about ACTH (2-24) (human, bovine, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (5R)-6-Cyano-5-hydroxy-3-oxo-hexanoic acid tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methylcyclohex-3-ene-1-carboxylic acid is an anionic compound that is used in the preparation of perfumes. This substance has been shown to have a cycloaddition reaction with nonionic detergents and isoprene, catalyzing the oxidation of terephthalic acid to ethylene. 4-Methylcyclohex-3-ene-1-carboxylic acid can also be used as a medicinal agent for aromatization or as a catalyst for the production of aldehydes.</p>

<p>Comanic acid is an organic compound that is a derivative of pyridinium. It can be synthesized from acetyl chloride and pyridine by reaction with silver ions in the presence of ethyl esters. Comanic acid has been shown to have anticholinergic activity and inhibit prostatic hypertrophy in rats. It is metabolized to propantheline, which has been shown to be a molecule that binds to chemokine receptors, inhibiting chemotaxis of activated T lymphocytes.</p>

<p>5-(4-Fluorophenyl)-3-isoxazolecarboxylic acid is a high quality reagent with CAS No. 33282-24-5. It is a complex compound that is useful as an intermediate for the synthesis of various fine chemicals. 5-(4-Fluorophenyl)-3-isoxazolecarboxylic acid also has a number of uses in the synthesis of speciality chemicals, research chemicals, and versatile building blocks for organic chemistry. As a reaction component, it can be used to synthesize compounds with different functional groups on their molecules.</p>

<p>3-Bromo-4-pyridinecarboxylic acid is a naphthyridine derivative that is used in drug development. It is a crystalline solid that can be dissolved in organic solvents. 3-Bromo-4-pyridinecarboxylic acid has been shown to have antiinflammatory properties and can be used as an oxidant. 3-Bromo-4-pyridinecarboxylic acid is being investigated as a receptor subtype for inflammatory diseases, and it has also been used to study the mechanism of chronic inflammatory diseases.</p>

<p>Please enquire for more information about Ethyl 1-N-Boc-3-oxopiperidine-4-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 4,5-dimethoxy-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1,4-Piperidinedicarboxylic acid, 4-aMino-, 1-(1,1-diMethylethyl) 4-ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Polyoxyethylated 12-hydroxystearic acid is a surface active agent that is used as an adjuvant in pharmaceutical preparations. Polyoxyethylated 12-hydoxystearic acid has been shown to have antimicrobial properties, which are due to its ability to disrupt the lipid membrane of bacteria and fungi. This agent also has a protective effect against the cytotoxicity of trifluoroacetic acid, which is often used in cell culture studies. Polyoxyethylated 12-hydoxystearic acid also has potential applications in cancer therapy because it can be conjugated with anticancer drugs to form liposome nanoparticles, which may allow for more efficient delivery of these drugs into cancer cells.</p>

<p>3-Cyanopropionic acid methyl ester is a compound that belongs to the class of aliphatic carboxylic acids. It is an intermediate in the production of adiponitrile and acrylonitrile. This compound is used as a feedstock for the manufacture of vinylene, which can be used to produce c1-6 alkyl. 3-Cyanopropionic acid methyl ester can be produced from propylene and hydrogen cyanide in a high salt, activated reaction system. It has been shown that this compound may have metabolic disorders due to its ability to inhibit fatty acid oxidation and increase viscosity. 3-Cyanopropionic acid methyl ester is a colorless liquid at room temperature with a boiling point of 154°C and a molecular weight of 98.14 g/mol.</p>

<p>Ferroceneacetic acid is a compound that has been shown to have chemiluminescent properties. It is a potent reductant and oxidant, which means that it can reduce or oxidize other compounds. Ferroceneacetic acid is also an active enzyme, and its redox potential changes depending on the concentration of ferrocene in the solution. Ferroceneacetic acid can be used as a model system for analytical chemistry and electrochemistry.</p>

<p>Please enquire for more information about 16a-Methyl prednisolone 21-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethyl 2-amino-4-thiazoleacetate is a supramolecular molecule that has the potential to be an anticancer agent. It inhibits the growth of tumor cells by binding to tyrosinase and hydrogen-bonding with chloride ions in solution. Ethyl 2-amino-4-thiazoleacetate also binds to a metal ion, such as zinc, which is important for biological functions. When it binds to these metals, it inhibits the enzyme hepg2 cell, which is involved in the synthesis of protein from RNA. Inhibition of this enzyme leads to decreased production of cytokines, which are molecules that regulate immune responses. This drug also has inhibitory activities against oral cephalosporins when used in combination with other drugs.</p>

<p>Medronic acid is a drug that is used for the treatment of chronic bowel disease. Medronic acid is a prodrug, which is converted to its active form, meclofenamic acid, by esterases in the bowel. Medronic acid has been shown to inhibit the activity of 5-lipoxygenase and cyclooxygenase-2 enzymes, and thereby reduce inflammation. It also decreases the production of prostaglandins and leukotrienes in humans. Medronic acid has been shown to be an effective treatment for bone cancer with no significant side effects. Medronic acid has been shown to inhibit the activity of 5-lipoxygenase and cyclooxygenase-2 enzymes, and thereby reduce inflammation. It also decreases the production of prostaglandins and leukotrienes in humans. Medronic acid has been shown to be an effective treatment for bone cancer with no significant side effects.</p>

<p>tert-Butyl acetoacetate is an organic molecule that contains nitrogen atoms. The structure of tert-butyl acetoacetate can be described as a planar molecule with two hydrogen atoms and two carbon atoms. One of the hydrogen atoms is bonded to the carbon atom in the middle, and the other hydrogen atom is bonded to one of the carbons on the outside. The compound has a coordination geometry with a sodium ion in its center, and it can also exist as an anion or as a cation. Tert-butyl acetoacetate was synthesized by reacting sodium carbonate with tert-butyl alcohol. This reaction is exothermic and produces tert-butyl acetoacetate along with water and sodium hydroxide. In addition, tert-butyl acetoacetate is toxicologically studied, which has shown that it does not have any carcinogenic effects or adverse effects on reproduction in rats at doses up to 2000 mg/kg/day</p>

<p>4-Phenoxybutyric acid is a molecule that is produced by filamentous fungi. It has been shown to inhibit the growth of many bacteria, including Staphylococcus aureus, Salmonella typhimurium, and Enterobacter aerogenes. 4-Phenoxybutyric acid binds to the receptor on the surface of the bacterial cell membrane and prevents it from functioning correctly. It also prevents the production of proteins necessary for growth and survival. This inhibition leads to a loss of energy in the cell, which eventually leads to death. The molecule has been shown to be effective in inhibiting bacteria even if they are resistant to antibiotics. 4-Phenoxybutyric acid has been shown to be more efficient than other methods for microbial biotransformation, such as dispersive solid-phase extraction or liquid-liquid extraction.</p>