Carboxylic Acids

<p>Applications 5-Formylfuran-2-boronic Acid Neopentyl Glycol Ester is a useful reagent in lapatinib synthesis.<br>References Radl, S., et al.: PCT Int. Appl. (2014), WO 2014059956 A1<br></p>

<p>Applications Used for preparation of Terfenadine (T114500) analogs.<br>References Uchida., et al.: Chem. Pharm. Bull., 37, 958 (1989),<br></p>

<p>Applications tert-Butyl (2-((4-Aminophenyl)amino)-2-oxoethyl)carbamate is an intermediate in the synthesis of (E)-2-Formamido-N-(4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)acetamide (F792100), a compound useful in organic synthesis.<br></p>

<p>Applications ethyl (4-aminophenyl)carbamate (cas# 57399-97-0) is a useful research chemical.<br></p>

<p>Applications 3-[5-(2-thienyl)-2-furyl]propanoic Acid (cas# 24090-38-8) is a useful research chemical.<br></p>

<p>Applications N-M-Tolylphthalamic Acid is used to prevent premature drop an anti shock treatment for pants. On ingestion is hydrolyzed to produce m-toluidine<br>References Pawar, G., et al.: Synth. Comm., 32, 1929-1936 (2002)<br></p>

<p>Applications Reagent used in the addition of cyclopropane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cave, C., et al.: Eur. J. Med. Chem., 25, 75 (1990), Kiyama, R., et al.: Chem. Pharm. Bull., 43, 960 (1995), Humphries, P., et al.: Bioorg. Med. Chem. Lett., 16, 6120 (2006),<br></p>

<p>Applications 2,4-Diaminobenzenesulfonic acid (cas# 88-63-1) is a useful reagent for improving the chlorine resistance and water permeability of polyamide (PA) membrane in water treatment.<br>References Meng, Q. W., et al.: ACS Applied Mat., 12, 35393 (2020)<br></p>

<p>Applications Clavulanic Acid 2-Amino-2,4,4-trimethylpentane Salt is an intermediate in the synthesis of Clavulanic Acid Potassium Salt (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reading, C. and Cole, M.: Antimicrob. Ag. Chemother., 11, 852 (1977); Ball, A.P., et al.: Lancet, 1, 620 (1980); Brogden, R.N., et al. Drugs, 22, 337 (1981)<br></p>

<p>Applications 6-Chloronicotinic Acid, is an organic building block used for the synthesis of various biologically active compounds, including inhibitors. It is an intermediate for the synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAFV600E inhibitors, and novel DNA-gyrase B inhibitors.<br>References Xie, Y., et al.: Bioorg. Med. Chem. Lett., 23, 2306 (2013); Shiroya, U., et al.: Med. Chem. Res., 22, 5227 (2013);<br></p>

<p>Applications (5-Formylfuran-2-yl)boronic Acid is a reagent used in Suzuki cross-couplings with deactivated aryl bromides and activated aryl chlorides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Trinh, T. N., et al.: Org. Biomol. Chem., 12, 9562-9571 (2014);<br></p>

<p>Applications 4-Acetylbutyric Acid is used in the synthesis of selective indomethacin analogues for AKR1C3 inhibition in the treatment of castrate-resistant prostate cancer. Also used to prepare PARP inhibitors for the treatment of cancer as well.<br>References Liedtke, A. et al.: J. Med. Chem., 56, 2429 (2013); Zhu, G. et al.: Bioorg. Med. Chem., 20, 4653 (2012);<br></p>

<p>Applications 3-Trimethylstannyl Benzoic Acid (cas# 161767-56-2) is a compound useful in organic synthesis.<br></p>

<p>Applications (9H-Purin-6-ylamino)-acetic acid (cas# 10082-93-6) is a useful research chemical.<br></p>

<p>Applications 2-Carboxyfuran-5-boronic acid, pinacol ester<br></p>

<p>Applications Ethyl 2-(2,6-Dichlorophenyl)acetate (cas# 90793-64-9) is a useful research chemical.<br></p>

<p>Applications 6-Bromohexanoic Acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosen, D. B., et al.: PCT Int. Appl. (2020), WO 2020254617 A1<br></p>

<p>Stability Hygroscopic<br>Applications Magnesium acetate tetrahydrate (cas# 16674-78-5) is a useful research chemical.<br></p>

<p>Applications meso-2,3-Dimercaptosuccinic Acid is used as a chelating agent and masking agent for cadmium in EDTA titration of zinc.<br>References Cavanillas, S., et al.: Anal. Chim. Acta., 746, 47 (2012); Liu, Y.X.,et al.: Adv. Materials. Res., 455, 1221 (2012); Banner, B., et al.: Clin. Toxicol., 50, 266 (2012);<br></p>

<p>Applications Mevinolinic Acid, Monoammonium Salt can be used as reactant/reagent in process for the preparation of the Simvastatin precursor, 2,2-dimethylbutanoic acid (1S,3R,7S,8S,8aR)-8-[(3R,5R)-7-(cyclopropylamino)-3,5-dihydroxy-7-oxoheptyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, via an amidation reaction.<br>References Khanna, J., et al.: Indian, IN 184809 A1 20000930 (2000)<br></p>

<p>Applications 3-(2-Aminoethoxy)propionic Acid (cas# 144942-89-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Oxirane-​2-​carboxylic Acid is used as reactant in the synthesis of glutathione peptidomimetics as components of antiparkinson prodrugs.<br>References More, S., Vince, R.: J. Med. Chem., 51, 4581 (2008);<br></p>

<p>Applications Methyl 2-(2-Hydroxyphenyl)acetate is used as a reactant in the preparation of caffeic acid phenylethyl esters as  antiproliferative agents.<br>References Xie, Jin, et al.: Bioorg. &amp; Med. Chem. Let., 27(2), 131-134 (2017)<br></p>

<p>Applications 3-Hydroxy-2,2,4-trimethyl-pentanoic acid is a urinary metabolite of the plasticizer 2,2,4-trimethyl-1,3-pentanediol Diisobutyrate (T798120).<br>References Astill, B., et al.: Toxicol. Appl. Pharm., 22, 387 (1972);<br></p>

<p>Applications 4-​Chloro-​3-​sulfobenzoic acid is a useful chemical for the preparation of pyridinylbiphenylcarboxamide derivatives for the use as nervous system agents.<br>References Wei, Z.L., et al.: PCT Int. Appl. 199pp. Patent 2009 CODEN:PIXXD2;<br></p>

<p>Applications 5-Formylfuran-2-boronic Acid Pinacol Ester could be useful for the diastereoselective synthesis of cyclic peptide macrocycles via Petasis borono-Mannich reaction<br>References Yamaguchi, A., et al.: Chem. Commun. (Cambridge, U. K.), 55, 10567 (2019)<br></p>

<p>Applications 2-Amino-4-hydroxybenzoic acid (cas# 38160-63-3) is a useful research chemical.<br></p>

<p>Applications 2-Ethylheptanoic Acid is used in the preparation of prostaglandin which is for for promoting bone growth<br>References Barrett, S., et al.: PCT Int. Appl., 331 (2015)<br></p>

<p>Applications 5-Pyrimidylboronic Acid, is one of the new heteroarylpyrimidine derivatives via Suzuki cross-coupling reactions.<br>References Saygili N, et al.: Org Biomol Chem. 2004 Mar 21;2(6):852-7. Epub 2004 Feb 23.<br></p>

<p>Applications 6-Fluoronicotinic acid<br></p>

<p>Applications Ethyl Acetate (2-13c, 99%) (cas# 58735-82-3) is a useful research chemical. This isotopic compound is used as a tracer in various experiments, for instance, during the conversion of oxygenated and hydrocarbon molecules to particulate matter for fuel purposes, and biosynthesis of terpenes.<br>References Aaron, E., et.al., Combust Flame, 161,2966-2974,(2014); Citron,C., et.al., Chem Comm,50,5224-5226,(2014);<br></p>

<p>Applications 5-(Ethoxycarbonyl)thiophene-3-boronic Acid is a useful reagent for preparing hydroxyimino(phenyl)propanones as GPBAR1 agonists.<br>References Bissantz, C., et al.: U.S. Pat. Appl. Publ. (2012), US 20120010190 A1<br></p>

<p>Applications 2-Butyl-4,6-dihydroxybenzoic Acid is an intermediate in preparation of compounds for study in primin and miconidin biosynthesis routes in Primula obconica.<br>References Horper, W., et al.: Phytochem., 41, 451 (1996);<br></p>

<p>Applications Methyl 2-Bromo-1-cyclopentenecarboxylate is a versatile reactant that can be derived from Cyclopentanone (C988395), which is a compound used in the synthesis of various simple and complex organic compounds. Cyclopentanone is also used in the synthesis of peptidase IV inhibitors for the treatment of type 2 diabetes.<br>References Imamoto, T. et al.: J. Am. Chem. Soc., 112, 5244 (1990); Augeri, D. et al.: J. Med. Chem., 48, 5025 (2005);<br></p>

<p>Applications Ethyl 2-Ethylacetoacetate was a useful reagent in systematic investigation of saccharomyces cerevisiae enzymes catalyzing carbonyl reductions.<br>References Kaluzna, I., et al.: J. Am. Chem. Soc., 126, 12827 (2004);<br></p>

<p>Applications Useful in the preparation of substances with antiinflammatory activity.<br></p>

<p>Applications 3-Acetamidophenyl acetate<br></p>

<p>Applications 5-Amino-2-bromobenzoic acid (cas# 2840-02-0) is a useful research chemical.<br></p>

<p>5-Norbornene-2-carboxylic acid is a reactive, carbonyl compound that has been used in metathesis reactions. In these reactions, the 5-norbornene-2-carboxylic acid reacts with sodium carbonate to form a mixture of hydroxy methyl and fluorine groups. The 5-norbornene-2-carboxylic acid can be prepared by reacting phenol with anhydrous hydrogen fluoride in the presence of sodium carbonate. This reaction produces a mixture of 5-norbornene-2 carboxylic acids, but also includes isomeric mixtures that are not useful as starting materials for synthesis. The 5-norbornene -2 carboxylic acid can also be synthesized from aliphatic hydrocarbons such as propylene or ethylene. It is important to note that the 5 - norborenene 2 carboxylic acid does not have any aromatic rings and is therefore</p>

<p>Please enquire for more information about 3-(3,5-Dimethyl-1H-pyrazol-1-yl)-2-methylpropanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,5-Dichloro-4-methoxybenzoic acid is a synthetic herbicide that inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). This enzyme is necessary for the synthesis of aromatic amino acids. 2,5-Dichloro-4-methoxybenzoic acid is used as a selective herbicide in plants grown in vitro to eliminate weeds. It is also used to control populations of wild plants and grasses. 2,5-Dichloro-4-methoxybenzoic acid has been shown to inhibit the growth of glyphosate resistant weed species by inhibiting EPSPS activity.</p>

<p>a functionalised glucoside</p>

<p>Please enquire for more information about DL-Aspartic acid dimethyl ester hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,5-Diphenyl-1H-pyrazole-3-carboxylic acid is a herbicide that belongs to the family of alkyloxycarbonyl amides. It is used in weed control and has shown good activity against many broadleaf weeds. 1,5-Diphenyl-1H-pyrazole-3-carboxylic acid inhibits the growth of plants by interfering with photosynthesis and the production of chlorophyll. The compound binds to the thylakoid membrane in chloroplasts, preventing electron transport and blocking the synthesis of carbohydrates from carbon dioxide and water. This leads to cell death as a result of oxygen depletion. 1,5-Diphenyl-1H-pyrazole-3-carboxylic acid also inhibits acetolactate synthase in plants, which produces amides that are important for protein synthesis.</p>

<p>4,6-Diaminobenzene-1,3-dicarboxylic acid is an inorganic copper compound that is used as a copper salt. It has been shown to be effective as a chelating agent for the treatment of copper toxicity. 4,6-Diaminobenzene-1,3-dicarboxylic acid binds to metal ions and forms a complex with them. This complex can then be excreted from the body through urine or bile.</p>

<p>Please enquire for more information about 3-(2-Ethyl-1H-imidazol-1-yl)-2-methylpropanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Tetrahydropyran-3-boronic acid pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 6-methyl-2-thioxo-4-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Ethylthiophene-2-carboxylic acid is a chemical compound that has been acetylated. It is often used as an intermediate in organic synthesis, especially as a building block for the production of pharmaceuticals and agrochemicals. 5-Ethylthiophene-2-carboxylic acid can be chromatographically separated by using strategies such as validation, algorithm, and regression. The chemical structure of this compound may be determined by using methods such as fingerprinting and gas chromatography. The structural isomers of this compound are naphthenic (5E) and butyllithium (5B). Chemists use 5E and 5B to profile the properties of this substance.</p>

<p>5-bromo-3-methylthiophene-2-carboxylic acid (5BmtCA) is a potential therapeutic that has been shown to have the same estrogenic activity as estradiol. It may be used for the treatment of osteoporosis and other conditions associated with estrogen deficiency, including resorption and bone loss. 5BmtCA is an amide with two phenyl groups at the C3 position, which are bioisosteres of the sulfur in estradiol. The substitutions on these phenyl groups can be changed to produce analogs with different properties. For example, 5BmtCA may be substituted with a ketone group at position C3 to produce the corresponding ketone analog 5BmtCK. This compound would be expected to have reduced bone resorption activity relative to 5BmtCA.</p>

<p>Ethyl (Ethoxymethylene) cyanoacetate is a chemical compound that belongs to the family of aldehyde compounds. It is a colorless liquid at room temperature, with an odor similar to that of acetic acid. The compound has been used in the synthesis of epidermal growth factor and diazonium salts. It has also been used in the production of anti-cancer drugs such as malonic acid, which inhibits tumor growth by inhibiting protein synthesis. Ethyl (Ethoxymethylene) cyanoacetate reacts with quinoline derivatives to form carbon disulphide, which can be used as an antimicrobial agent and insecticide.</p>

<p>Please enquire for more information about 1-Benzyl-3-phenyl-1H-pyrazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethyl 4-chloroacetoacetate is a chiral organic compound that is synthesized by the asymmetric synthesis of ethyl chloroacetate. This reaction is performed in an organic solution, using sodium salts as the solvent. The expression plasmid and logarithmic growth phase are needed for the enzyme catalysis and stereoselective reactions. The reaction solution is recombined with hydrochloric acid and chiral compound to produce high yields of ethyl 4-chloroacetoacetate.</p>

<p>Please enquire for more information about 1-(4-Isopropylphenyl)-5-oxopyrrolidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pyrimidine-5-carboxylic acid is a synthetic, nucleophilic pyrimidine compound that is used in the laboratory for the synthesis of other compounds. It has been shown to inhibit the growth of Leishmania and Staphylococcus bacteria. Pyrimidine-5-carboxylic acid binds to the malonic acid moiety of phosphoenolpyruvate carboxykinase and inhibits its activity, leading to a reduction in cellular respiration. This drug also has clinical development potential as an analgesic with modulating properties.</p>

<p>Please enquire for more information about L-Pyroglutamic acid pentachlorophenyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 1H-pyrrolo[2,3-b]pyridine-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Sulfoglycolithocholic acid disodium is a potential biomarker for inflammatory bowel disease. It is also used as an analytical method to measure bile acids in the blood. 3-Sulfoglycolithocholic acid disodium has been shown to be a strong indicator of liver inflammation and hepatitis. This compound can also be used as a diagnostic tool for infectious diseases, such as HIV and hepatitis C, by measuring serum bile acids levels. The level of this molecule can be measured in the blood and urine of patients with bowel disease, such as ulcerative colitis or Crohn's disease. 3-Sulfoglycolithocholic acid disodium can also be used to diagnose atrial fibrillation.</p>

<p>Methyl 2,2,2-trifluoroacetate is a reactive compound with the chemical formula CHF. It can be used as a glycol ether and reacts with acid to form an alkanoic acid. Methyl 2,2,2-trifluoroacetate also reacts with a hydroxyl group to produce a molecule with two carboxylic acid groups. The kinetic data of this reaction has been determined using gas chromatography. This compound can also be used as a solid catalyst in reactions that require kinetic energy. Methyl 2,2,2-trifluoroacetate is not toxic to humans and has been found to be safe for use in analytical techniques.</p>

<p>Please enquire for more information about Delta-9(11)-Fluorometholone acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Indole-3-acetyl-L-glutamic acid is an endogenous substance that is found in plants. It is the conjugated form of indole-3-acetaldehyde and L-glutamic acid. Indole-3-acetylglutamic acid has shown to have antioxidant potential and can be used to regulate plant growth, as well as protect against environmental stresses. Indole-3-acetylglutamic acid also has a role in regulating the production of other hormones, such as ethylene and auxin, which are involved in plant growth regulation.</p>

<p>Please enquire for more information about 4-(N-Methylamino)phenylboronic acid pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Trifluoromethylcyclopropane-1-carboxylic acid is a ketone that is used in research in organic chemistry for the preparation of imidazole. It can be prepared by the transformation of ethyl 2-(trifluoromethyl)acrylate, and is also obtained from 1,4-dichloroacetone. 1-Trifluoromethylcyclopropane carboxylic acid has been shown to have some medicinal properties. It has been used in research on cancer cells and as an anti-inflammatory agent. The compound has a steric effect on the body and can be used as a weight loss drug, with one kilogram of 1-Trifluoromethylcyclopropane carboxylic acid being equivalent to 3 kilograms of weight loss.</p>

<p>Oxazepam acetate is a chiral drug that has enantiomeric forms. Oxazepam acetate is converted to the corresponding lorazepam by hydrolysis of the acetate ester group. This drug is an analytical method for determining the concentration of oxazepam in human serum and rat liver microsomes. It also has a stereoselective effect on nucleophilic attack, which means it only reacts with one of two possible sites in the molecule. Oxazepam acetate can be used to treat insomnia, anxiety, and seizure disorders.</p>

<p>Please enquire for more information about tert-Butyl 4-hydroxy-1-oxa-9-azaspiro[5.5]undecane-9-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cobalt(II) acetate tetrahydrate is a model system that can be used to study the structures of coordination complexes. The cobalt ion has a coordination geometry with two water molecules, two oxygen atoms from the acetate anion, and one proton from the hydroxide anion. The crystal structure is composed of six-membered rings of alternating metal ions and oxygen atoms. The reaction solution contains excess sodium hydroxide and water vapor. It was determined that cobalt(II) acetate tetrahydrate reacts electrochemically at low frequencies as well as with 5-hmf, an oxidizing agent, in the presence of sodium citrate as an oxidation catalyst.</p>

<p>Please enquire for more information about 4-(1H-Pyrazol-1-yl)butanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Trifluoroacetic acid is an organic acid that is used in the synthesis of esters, ethers, and amides. It can be used to produce 3,4,5-triacetoxybenzoic acid (TABA), which inhibits the proliferation of leukemia cells. TABA binds to the active site of the protein runx2, which is involved in development and differentiation. It also inhibits vibrational spectra and chemical profiles that are related to cancer cell growth. TABA has been shown to induce autophagy through activation of AMPK signaling pathways in leukemia cells. TABA also inhibits lipid accumulation by inhibiting the expression of genes such as SREBP1c and ACC2.</p>

<p>Please enquire for more information about Methyl 5-bromo-1H-pyrazole-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-[2-(5-Methyl-1H-indol-3-yl)ethyl]-5-oxopyrrolidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>