Glycoscience

Stability Hygroscopic
Applications Guaiacol-beta-D-glucopyranoside-d3, is a labeled analogue of Guaiacol-beta-D-glucopyranoside (G245565), a Guaiacol Conjugate, that has shown to present in fermentation of grapes that had been exposed to bushfire smoke and can potentially yield unpalatable, smoke-affected wine.
References Hayasaka, Y.m et al.: J. Arg. Food Chem., Vol. 58, Issue 4, P: 2076; 2081 (2010);

Applications L-Ribulose is a rare sugar produced mainly from the abundant L-arabinose via enzymatic conversion.
References Liu, X. et al.: J. Agri. Food Chem., 67, 4868 (2019);

Applications Intermediate in the preparation of Citicoline (C508050), a naturally occurring nucleotide.

Applications Streptidine, is a metabolite derivative of Streptomycin (S687500), an antibiotic (antimycobacterial) drug, used for patients suffering from tuberculosis or other infectious diseases.
References Granados, O., et al.: Histology and Histopathology, 20(2), 357 (2005);

Applications A novel glucosylation enzyme.
References Kuriki, T., et al.: J. Biosci. Bioeng., 87, 557 (1999), Meulenbeld, G., et al.: Biotechnol. Bioeng., 70, 363 (2000), Moon, Y., et al.: J. Agric. Food Chem., 54, 1230 (2006),

Applications A naturally occuring fibre found in the shells of shellfish. Used for the analysis of Chitinase.
References Skujins, J.J., et al.: Arch. Biochem. Biophys., 111, 358 (1965).

Applications A pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery via M cells of Peyer's patches.
References Pukanud, P. et al.: Drug Delivery, 16, 289 (2009); Knowles, D.J. et al.: J. Gen. Microbiol., 108, 17 (1978);

Applications An anthocyanin responsible for red pigment in fruits and berries. It is an antioxidant, protecting the cell against damage from SOD.
References Riihinen, K., et al.: Food Chem., 110, 156 (2008), Khanizadeh, S., et al.: J. Food Comp. Anal., 21, 396 (2008), Viskelis, P., et al.: J. Food Sci., 74, C157 (2009), Comeskey, D., et al.: J. Agric. Food Chem., 57, 2035 (2009),

Stability Hygroscopic
Applications A substrate for N-acetyl-ß-D-glucosaminyltransferase. Also an inhibitor of 1-ß-3-galctotransferase. Blocks the apical biosynthetic pathway in polarized HT-29 cells.
References Delacour, D., et al.: J. Cell Biol., 169, 491 (2005), Suzuki, O., et al.: Int. J. Oncol., 26, 1063 (2005),

Applications Galactinol Hydrate is an α-galactoside of Inositol (I665995), which is the structural basis for a number of signaling and secondary messenger molecules including; insulin signal transduction, cytoskeleton assembly, nerve guidance, membrane potentials, serotonin activity and the breaking down of fats and reducing cholesterol.
References Graca, G., et al.: J. Prot. Res., 9, 6016 (2010); Rovio, S., et al.: Food Chem., 124, 1194 (2010);

Stability Hygroscopic
Applications A naturally occuring deaminated sialic acid, exclusively located at the non-reducing end of the sialyl chains. KDN is a sialic acid derivative with potential for anticancer activity. KDN has also been seen to be in elevated levels in human prostate cancer cells.
References Nadano, D., et al.: J. Biol. Chem., 261, 11550 (1986); Tiralongo, J. et al.: Carb. Mod. Biocatal., 477 (2012); Yabu, M. et al.: Glycobiol., 23, 634 (2013);

Applications 1,6-Anhydro-β-D-glucopyranose is a carbohydrate contains in liquid smoke flavorings.
References Kim, K., et al.: Agric. Biol. Chem., 38, 53 (1974), Guillen, M., et al.: Food Chem., 58, 97 (1997), Guillen, M., et al.: J. Agric. Food Chem., 46, 1276 (1998),

Applications Diglycerol was used in cosmetic deodorants. It is also a component in thickening and gelatation agents.
References Wolf, F., et al.: Eur. Pat. Appl. (1996), EP 691125 A1 19960110.; Yamada, M., et al.: Jpn. Kokai Tokkyo Koho (1980), JP 55025430 A 19800223.

Stability Hygroscopic
Applications Glycosides isolated from various species of Digitalis. Cardiotonic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Novotny, J., et al.: J. Biol. Chem., 258, 14433 (1983), Farr, C., et al.: J. Med. Chem., 45, 3257 (2002), Van Dongen, M., et al.: Drug Discov. Today, 7, 471 (2002),

Applications Regulation of N-glycolylneuraminic acid biosynthesis in rat and mouse liver.
References Malykh, Y., et al.: Biochimie, 83, 623 (2001), Angata, T., et al.: Chem. Rev., 102, 439 (2002), Soh, N., et al.: Anal. Sci., 18, 1159 (2002), Taylor, P., et al.: Clin. Biochem., 38, 328 (2005),

Stability Very Hygroscopic
Applications Fructoseglutamic Acid Disodium Salt is an Amadori compound (derivatives of aminodeoxysugars) that is formed in food (such as dehydrated fruits such as tomatoes and carrots) as a result of the Maillard reactions.
References Baltes, W.: Food Chem., 9, 59 (1982); Sanz, M., et al.: J. Agr. Food Chem., 49, 5228 (2001); Wellner, A., et al.: J. Agr. Food Chem., 59, 7992 (2011)

Stability Hygroscopic
Applications Yuanzhen sugar is a polysaccharide polymer, containing a certain amount of fructooligosaccharides.
References Watanabe, T., et al.: Biosci. Biotech. Biochem., 72, 3167 (2008), You, Y., et al.: J. Agric. Food Chem., 57, 709 (2009),

Applications Derivative of Neuraminic Acid
References Oetke, C., et al.: J. Biol. Chem., 277, 6688 (2002),

Applications Impurity of β-cyclodextrin (C987830), a cyclic oligosaccharide produced from starch via enzymatic conversion.
References Johnson, M.D., et al.: J. Pharma. Sci., 83, 1142 (1994); Jain, A.C., et al.: Int. J. Pharma., 212, 177 (2001);

Stability Hygroscopic
Applications Bis(4-hydroxyphenyl) Sulfone O-β-D-Glucuronide is the glucuronide derivative of Bis(4-hydroxyphenyl) Sulfone (B447390); a compound that is commonly used as a reactant in epoxy reactions. It is also used as a latent thermal catalyst for epoxy resin.
References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012)

Applications Labelled D-Mannitol (M165000). D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Applications An inhibitor of the enzyme glucose dehydrogenase.
References Cozier, G.E. et al.: Biochem. J., 340, 639 (1999);

Applications 2-O-(a-D-Mannopyranosyl)-D-mannopyranose is a component of yeast Candida catenulata that may provide antigenic effects.
References Kobayashi, H. et al.: Adv. Microbiol., 3, 222 (2013);

Stability Temperature Sensitive
Applications Methyl 2,3,4-Tri-O-isobutyryl-D-glucopyranuronate (cas# 1190403-86-1) is a compound useful in organic synthesis.

Applications D-Galactose-3-sulfate potassium salt is a sulfated conjugate of D-Galactose (G155250), a epimer of Glucose (G595000) that is found in milk and sugar beets as well as being synthesized by the body.
References Turvey, J.R., et al.: J. Chem. Soc., 2242 (1963); Bowker, D.M., et al.: J. Chromatograph., 22, 486 (1966);

Applications An inhibitor of peptic hydrolysis and stomach acidity. Used as an anti-ulcerative.
References Mayberr, J.F., et al.: Brit. J. Clin. Pract., 32, 291 (1978); Brogden, R.N., et al.: Drugs, 27, 194 (1984);

Applications N,N’,N’’-Triacetyl Chitotriose is a multivalent glycosides with strong crosslinking activity for lectin as a specific coagulant.
References Bhattacharyya, L., et al.: Biochemistry, 29, 7523 (1990), Sacchettini, J., et al.: Biochemistry, 40, 3009 (2001), Maierhofer, C., et al.: Bioorg. Med. Chem., 15, 7661 (2007),

Stability Hygroscopic
Applications An inhibitor of lysozyme, reverses myocardial depression and lessens norepinephrine requirements in Escherichia coli sepsis in dogs.
References Lefer, A., et al.: Am. J. Physiol., 213, 492 ( 1967), Parrillo, J., et al.: J. Clin. Invest., 76, 1539 (1985), Mink, S., et al.: J. Mol. Cell. Cardiol ., 35, 265 (2003),

Applications L-Glyceric acid (CAS# 28305-26-2) is a useful research chemical compound.

Applications 2-Acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-1,6-di-O-N-acetyl-α-D-muramic Acid (cas# 475502-13-7) is a compound useful in organic synthesis.

Applications L-Isomer of D-galactose (G155250), a C-4 epimer of Glucose (G595000) found in milk and sugar beets as well as being synthesized by the body. Potential use in oral therapy for nephrotic syndrome in focal and segmental glomerulosclerosis.
References De Smet, E. et al.: Nephrol. Dial. Transplant., 24, 2938 (2009); Kivele, R. et al.: Carb. Pol., 85, 645 (2011);

Stability Hygroscopic
Applications N-Acetyllactosamine is used in the expansion of a multi-funcational natural scaffold for the study of structural space of the Galectin-1-Ligand interaction. Also, it is used to identify the impurity as an imidazoline ring structure.
References Bertleff-Zieschang, N., et al.: ChemBioChem, 18, 1477-1481 (2017); Duff, R. J., et al.: J. Chromatogr. A, 1501, 61-67 (2017);

Applications 1-Methoxy Empagliflozin is an impurity in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).
References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);

Applications (2S,3R,4R,5R,6R)-3-Acetamido-6-(acetoxymethyl)tetrahydro-2H-pyran-2,4,5-triyl Triacetate is used to synthesize selenium monosaccharide as metabolic biomarker.
References Deng, Shengyuan. et al., Faming Zhuanli Shenqing(2020);

Applications Isotope labelled analog of α-D-Galactose 1-Phosphate, the phosphate conjugate of α-D-Galactose (G155260), a natural aldohexose which is ubiquitous in bacteria, plants, and animals, including human brains.
References Sang, J.L., et al.: J. Bacteriol., 190, 7932 (2008);

Applications D-(+)-Cellotetraose (cas# 38819-01-1) is a compound useful in organic synthesis.

Applications Ligand used for the preparation of an affinity resin highly specific for glucosidase I purification. Glucosidase I is involved in the post-translational processing of N-linked glycoproteins.
References HettKamp, H., et al.: Eur. J. Biochem., 142, 85 (1984); Shailubhai, K., et al.: Biochem. J., 247, 555 (1987); Bause, E., et al.: FEBS, 278, 167 (1991)

Applications An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called Ψ synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that β-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes.
References Ferré-D'Amaré A.R. et al.: Curr. Opin. Struct. Biol., 13, 49 (2003); Hamma, T. et al.: Chem. Biol., 13, 1125 (2006); Liang, X.H. et al.: RNA, 8, 237 (2002); Monobe, M. et al.: Mut. Res. Gen. Toxicol. Env. Mutagen., 538, 93 (2003);

Applications Sucrose Monocaprate is a potentially useful biochemical also known as sucrose monodecanoate.

Applications Glucosinolate analog of Glucoraphanin found in cruciferous vegetables such as broccoli and cauliflower.
References Lee, J.G. et al.: Horticult. Env. Biotech., 50, 509 (2009); KIm, J.K. et al.: Food Chem., 119, 423 (2010);

Applications 2-Deoxy-D-ribose induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
References Fico, A., et al.: Free Radical Biology & Medicine, 45, 211 (2008),

Stability Hygroscopic
Applications A constituent of certain mucopolysaccharides.
References Hoffman, P., et al.: Science, 124, 1252 (1956), Meyer, K: Biochim et Biophys. Acta, 21, 506 (1956), Cifonelli, J.A., et al.: Federation Proc., 16, 165 (1957), Cifonelli, J.A., et al.: J. Biol. Chem., 233, 541 (1958)

Applications Alginic Acid Sodium Salt, can be used as a flavorless gum. It is used by the foods industry to increase viscosity and as an emulsifier. It is also used in indigestion tablets and the preparation of dental impressions.
References Raymond C. R., et al.: Adipic Acid, Handbook of Pharmaceutical Excipients, 11 (2009); Augst, A. et al.: Macromol. Bio. 6, 623 (2006); Chen, S. et al.: J. Contorl. Rel., 96, 285 (2004);

Stability Light Sensitive, Temperature Sensitive
Applications Norbixin is a carotenoid used as cosmetic pigment and food colouring additive.
References Bouvier, F., et al.: Science, 300, 2089 (2003); Breithaupt, D.: Food Chem., 86, 449 (2004);

Applications A base component of hemicellulose and pectin, critical biopolymers.
References Alcaro, S., et al.: Bioorg. Med. Chem., 12, 1781 (2004),

Applications Dextrin (cas# 9004-53-9) is a versatile polymer used in a variety of applications such as in the preparation of probiotic beer and polymer solar cells.
References Senkarcinova, B.; et al.: LWT, 100, 362 (2019); Lin, P.; et al.: ACS Sustainable Chem. Eng., 6, 14621 (2018).

Stability Hygroscopic
Applications The N-Glucoside of Benzocaine (B202970) with anesthetic activity. A potential sun-screening agent.
References Rybczynska, B. et al.: Parfum. Kosm., 48, 125 (1967); Nikolin, A. et al.: Glas. Hemi. Tehnol. Bosne Herceg., 16, 93 (1968);

Applications D-Glucose 6-phosphate solution is a sarcoendoplasmic reticulum calcium ATPase activity inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Okubo, M. et al.: Metab., 37, 1171 (1988); Henriksen, J.E. et al.: Metab. Clin. Exp., 46, 598 (1996); Oyama, J. et al.: Enndocrinol., 80, 707 (1967); Newsholme, E.A. et al.: Biochem. J., 104, 47P (1967);

Stability Hygroscopic
Applications A derivative of D-Mannosamine (M167000).
References Pukanud, P. et al.: Drug Delivery, 16, 289 (2009);

Stability Hygroscopic
Applications Isotope labelled analog of α-D-Galactose 1-Phosphate, the phosphate conjugate of α-D-Galactose (G155260), a natural aldohexose which is ubiquitous in bacteria, plants, and animals, including human brains.
References Sang, J.L., et al.: J. Bacteriol., 190, 7932 (2008);

Applications 2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-D-glucono-1,5-lactone (cas# 34051-37-1) is a compound useful in organic synthesis.
References Vocadlo, D., et al.: Biochem., 44, 12809 (2005),

Applications A carbohydrate metabolism regulator that has been shown to inhibit gluconeogenesis from lactate plus pyruvate and from substrates that enter the gluconeogenic pathway as triose phosphate.
References Joet, T., et al.: Biochem. J., 381, 905 (2004), Girardin, E., et al.: J. Biol. Chem., 280, 38059 (2005), Nghiem, N., et al.: App. Biochem. Biotechnol., 141, 335 (2007),

Applications Laminarin is a storage glucan and is now used to study it’s interaction with laminarinase as its substrate.
References Dai, H., et al.: Glycobiol., 22, 1673 (2012); Park, H.K., et al.: Int. J. Molec. Med., 30, 734 (2012); Gururaj. H. B., et al.: Asian. J. Plant. Sci. Res., 2, 490 (2012);

Applications Galactosamine-6-phosphate was identified as a component of the coat of the Bacillus megaterium QM B1551 spore. It was one of the main constituents of the outermost layer of the spore coat, but it was absent from the other integuments including the cortex. These findings suggest that galactosamine-6-phosphate comprises the phosphorus-containing skeleton structure of the spore coat.
References Dabich, D., et al.: J. Biol. Chem., 241, 415 (1966), Nasu M., et al.: Microb. Immunol., 28, 181 (1984),

Impurity Diosmin EP Impurity D
Applications 6-Iodo Diosmin (Diosmin EP Impurity D) is a Diosmin (D485200) impurity.