Glycoscience

4,6-O-Benzylidene-D-glucose is a potent inhibitor of the enzyme dibutyltin oxide, which is involved in the synthesis of energy. It has been shown to have clinical activity in rat cardiomyocytes and has been tested in clinical studies. 4,6-O-Benzylidene-D-glucose inhibits enzymes by forming hydrogen bonds with their substrates. This compound also interacts with hydrochloric acid to form a stable complex that prevents it from interacting with other molecules. 4,6-O-Benzylidene-D-glucose is rapidly broken down into glucose and benzaldehyde when it reacts with carbonyl groups or amines. The asymmetric synthesis of this compound can be achieved using an intramolecular hydrogen transfer reaction.
4,6-O-Benzylidene glucose is derived from D-mannose derivatives and contains a hydroxyl group on the central carbon

Isosorbide dinitrate is a drug that belongs to the class of nitrates. It is used in the treatment of angina pectoris, as well as congestive heart failure and chronic heart failure. Isosorbide dinitrate has been shown to cause caspase-independent cell death in human leukemia cells and breast cancer cells. This may be due to its ability to inhibit mitochondrial membrane potential and interfere with intracellular calcium mobilization. The optimum concentration for isosorbide dinitrate is 10 µM, which inhibits the growth of bacteria, including Mycobacterium tuberculosis and Salmonella enterica serovar Typhimurium. The drug also inhibits the production of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α by inhibiting c-jun phosphorylation. Isosorbide dinitrate also has anti-inflammatory properties, which may be due to its ability to inhibit 4-hyd

2-Deoxy-2-fluoro-D-galactose, also called 3-fluoro-6-hydroxymethyl-tetrahydro-pyran-2,4,5-triol, can be added to the medium of primary cultured rat hepatocytes to inhibit N-glycosylation of proteins. Immunoglobulin G (IgG) is the most common antibody found in blood and 2-deoxy-2-fluoro-D-galactose modifies the galactosylation of the N-linked glycan in the IgG-Fc receptor.  We also have this product from a non-animal origin, MD71984.

L-Glucurono-3,6-lactone is an acetonide that is a derivative of L-glucose. L-Glucurono-3,6-lactone can be used as a precursor for the synthesis of polyhydroxybutyrate (PHB).

1,5-Anhydro-2,3,4-tri-O-benzoyl-D-threo-pent-1-enitol is a high purity compound that is synthesized from D-threo pent 1 enitol. It is a sugar that belongs to the category of complex carbohydrates. This product can be custom synthesized and modified according to customer requirements.

2-Deoxy-L-fucose is a sugar that is found in the human body. It has been shown to have anti-tumour properties and can be used as a chemotherapeutic agent in the treatment of solid tumours. 2DFL binds to the receptor for fucose, which is expressed in many types of cancer cells. It also inhibits DNA synthesis by stabilizing a complex between the sugar and dna template, inhibiting the binding of monoclonal antibodies to cancer cells, and preventing glycosidic bond formation on cancer cells. 2DFL has also been shown to inhibit microbial biotransformation and cell culture.

Ulvan is a complex carbohydrate that has been modified with methylation, fluorination, and click chemistry. Ulvan can be used in the synthesis of oligosaccharides and saccharides. It is also an important glycosylation product. Ulvan has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Pregnanediol 3α-O-β-D-glucuronide is a glucuronide metabolite of progesterone, which is a key steroid hormone in the reproductive system. This compound is derived from the metabolic conversion of progesterone, primarily within the liver, where it undergoes glucuronidation. This process involves the addition of glucuronic acid, mediated by the enzyme UDP-glucuronosyltransferase, enhancing the compound’s solubility for renal excretion.

Propofol-4-Hydroxy-4-D-glucuronide is a fluorinated monosaccharide that has been synthesized using the glycosylation, polysaccharide and modification methods. This compound is a custom synthesis that has been modified with methylation and click chemistry. The CAS number for this product is 54910-87-6. This product is a complex carbohydrate with high purity.

Methyl 2,3,4-tri-O-benzyl-β-D-glucopyranoside is a modified sugar. It can be used in the synthesis of oligosaccharides and polysaccharides. This product is stable to organic solvents and has high purity. Methyl 2,3,4-tri-O-benzyl-β-D-glucopyranoside can be fluorinated by reacting with hydrogen fluoride gas to produce methyl 2,3,4-[tri(trifluoromethyl)oxy]benzyl β D glucopyranoside. The product is also available in the form of click modification (a type of chemical modification). Methyl 2,3,4-tri-O-benzyl-β D glucopyranoside is a custom synthesis that is CAS No. 435680 3.

Lactitol is a polyol sugar alcohol that has been used in the treatment of chronic viral hepatitis. It is also used to treat constipation, irritable bowel syndrome, and other gastrointestinal disorders. Lactitol is metabolized by certain types of bacteria and can have a laxative effect. Lactitol is not absorbed in the human intestine and thus does not cause an increase in blood sugar levels. Lactitol has been shown to be effective against microbial translocation and bacterial overgrowth in the gut, which may be due to its ability to lower pge2 levels and inhibit histological changes.

N-acetyl D-glucosamine (GlcNAc) is an aldohexose (2-acetamido-2-deoxyglucose) in which the hydroxyl group at position 2 is replaced by NHAc (Collins, 2006). N-acetyl D-glucosamine forms the exoskeletons of molluscs and insects as the building block of the polysaccharide chitin (Rudrapatnam, 2003). N-acetyl D-glucosamine is a key component of N- and O-linked glycans, present in glycolipids and the glycosaminoglycan hyaluronic acid (Fallacara, 2018). A recent study has suggested that N-acetyl D-glucosamine may have therapeutic potential for COVID-19 as it affects the spike protein-ACE2 receptor interaction during the infection with SARS-CoV-2 virus (Baysal, 2021).