Glycoscience

<p>Cancer-associated carbohydrate antigen</p>

<p>D-Allono-1,5-lactone is a glycoside that has been custom synthesized. It is a high purity product with a variety of modification options. This compound can be used for the synthesis of sugars, Click modification, fluorination, and glycosylation. D-allono-1,5-lactone has CAS No. 894408-50-5 and is classified as an oligosaccharide or sugar. It can also be methylated or modified to create saccharides or complex carbohydrates.</p>

<p>Ziyuglycoside I is a naturally occurring compound that has been shown to have physiological effects on skin cells. It has been found to bind to collagen and the matrix of skin cells, which may be its mechanism of action. Ziyuglycoside I also has an anti-inflammatory effect, which may be due to its ability to inhibit transcription-polymerase chain reactions (PCR). It has been shown to have antimicrobial activity against some strains of bacteria that are resistant to antibiotics such as erythromycin and tetracycline. Ziyuglycoside I has potential applications in the treatment of infectious diseases and inflammatory skin diseases.</p>

<p>Lewis Y-O-(CH2)8-biotin is a carbohydrate with the chemical formula (CHO)(CO)3OH. It is a methylated and glycosylated oligosaccharide that has been custom synthesized for use in biotechnology applications. Lewis Y-O-(CH2)8-biotin has been fluorinated at the C5 position to improve its stability and prevent hydrolysis, which may be due to its high purity. This carbohydrate is not commercially available and must be custom synthesized.</p>

<p>Lumefantrine b-D-Glucuronide is an anti-malarial drug with a high purity and custom synthesis. It can be synthesized by click modification, fluorination, glycosylation, and methylation of the sugar. Lumefantrine b-D-Glucuronide is an oligosaccharide that contains saccharides and complex carbohydrates. Lumefantrine b-D-Glucuronide is a sugar modified to produce a molecule that is more soluble in water. It has a CAS No. 460745-26-0 and can also be found under the name Oligosaccharide, Monosaccharide, Saccharide, Carbohydrate.</p>

<p>1,2:3,4-Di-O-isopropylidene-a-D-galactopyranose, also known as diacetone-D-galactose and galactose diacetonide, is a partially protected monosaccharide building block with isopropylidene groups on the 1,2 and 3,4 hydroxyls. The 6-hydroxyl is unprotected and able to undergo a variety of chemical transformations, such as glycosylation acting as a glycosyl acceptor to form 1,6-linked disaccharides.</p>

<p>Methyl 2-benzyloxycarbonylamino-2-deoxy-a-D-glucopyranoside is a monosaccharide that is modified with fluorine. The modification of the sugar molecule can be done by either a click or an oxidative process. In the case of this product, the modification was done by addition of fluorine to the methyl group on the second carbon atom of the benzyloxycarbonyl group. This product belongs to CAS No. 4704-15-8 and has a high purity. It is also a complex carbohydrate and consists of saccharides and sugars. Methyl 2-benzyloxycarbonylamino-2-deoxy-a-D-glucopyranoside can be used in polysaccharides and saccharides, as well as other applications related to carbohydrates such as modifying glycoproteins and glycolipids, as well as being used in pharmaceuticals such</p>

<p>(1S) -1- [(2S, 3S,4R) -4-Hydroxymethyl-3- hydroxy- N-methyl-1- azetidinyl] -1, 2- ethanediol is a synthetic sugar that can be used as a glycosylation or methylation agent. It is a white powder with a molecular weight of 342. The purity of this product is &gt; 98%. This product has CAS No. 517862-65-8.</p>

<p>glycosidase enzyme inhibitor. Formerly code MC04178.</p>

<p>D-Fucose is a sugar that can be synthesized in vitro. It is a component of the xanthurenic acid pathway, which is involved in the synthesis of l-arabinose. D-Fucose has been found to have anti-leukemic effects and to inhibit enzyme activities in vitro. It has also been shown to bind to the toll-like receptor, α1-acid glycoprotein, and surface membranes. A hydroxyl group at position 1 on the fucose molecule may be important for this binding. D-Fucose's biological properties are related to its structural analysis and the cell receptors it binds with. D-Fucose has an optimum pH level of 7, so it cannot survive outside of a neutral environment. It does not need any biological cofactors or enzymes for its synthesis, so it is classified as a nonessential nutrient. D-Fucose is also used in blood groups because it contains an antigen</p>

<p>The chemical name of the compound is 4-Methoxyphenyl 2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-a-D-glucopyranosyl)-3,4-di-O-benzyl--6--O--pivaloyl-[a]-D--mannopyranoside. The molecular formula is C47H69NO17. The molecular weight is 838.10 g/mol. This product is a white to off white solid that has no odor and a sweet taste. Compound can be custom synthesized to customer's specification and purity requirements. The CAS number for this compound is 1820574-70-6.</p>

<p>This compound is a glycosylation product of the monosaccharide fucose and the disaccharide 2-O-benzyl-a-L-thiofucopyranoside. It is a custom synthesis that has been modified by fluorination, methylation and click chemistry. This product is available in high purity and with a CAS No. 183051-73-2.</p>

<p>1,5-Anhydro-D-glucitol 6-dihydrogenphosphate is a biochemical analog. It has been shown to have anti-inflammatory effects in rat models of inflammatory bowel disease and metabolic disorders. 1,5-Anhydro-D-glucitol 6-dihydrogenphosphate inhibits the activity of bacterial enzymes that catalyze protein glycosylation. It also blocks the production of inflammatory cytokines and colony stimulating factors. The enzyme inhibition may be due to its ability to inhibit the synthesis of D-glucose from D-galactose by blocking the enzyme DALR (deleted in liver cancer).</p>

<p>Benzyl 4- O- b- D- glucuronyl-b- D- xylopyranoside is a synthetic derivative of benzyl 4- O- b- D- glucuronylxylose. It has been shown to be a good substrate for glycosylation, click modification and fluorination. This product has been custom synthesized for the synthesis of complex carbohydrate, which is an oligosaccharide. It is also used in methylation reactions.</p>

<p>Tri-b-GalNAc-6-aminohexanoate TFA is the peracetylated TFA salt from MT184237. It is a synthetic ligand designed to target the asialoglycoprotein receptor (ASGPR) on hepatocytes. The three terminal beta-N-acetylgalactosamine (GalNAc) sugars provide an efficient ASGPR binding. It serves as a platform for lysosomal targeting chimera (LYTAC) development, allowing for the creation of chimeras that specifically target unwanted proteins for degradation within hepatocytes. In addition, tri-b-GalNAc-6-aminohexanoate facilitates the delivery of therapeutic cargo, such as RNA or Cas9 complexes, directly to hepatocytes via ASGPR-mediated endocytosis. This approach is promising for gene therapy and RNAi applications in the liver due to the specificity of ASGPR targeting and the versatility of the conjugation moiety.</p>

<p>Phenyl 2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside is an analog of a sugar molecule. This compound can be synthesized by the metathesis reaction between phenyl 2,3,4,6-tetra-O-acetyl-α-(2′→3′)-D-thiomannopyranoside and bis(trimethylsilyl) sulfate in the presence of polyphosphoric acid and potassium sulfate. The yield of this synthesis is high and can be increased with the addition of potassium sulfonate as a cofactor.</p>

<p>N-Azidoacetylmannosamine, also called ManNAz and 2-[(2-azidoacetyl)amino]-2-deoxy-D-mannose, is a click reagent for metabolic labelling of ManNAc. The azide is able to react with an alkyne in a 1,3-dipolar cycloaddition reaction (click chemistry) to enable linking to a fluorescent probe or a biotin. N-Azidoacetylmannosamine has been used in the chemical modification of glycoproteins to improve their in vivo efficacy and to label them for detection.</p>

<p>Methyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-a-D-galactopyranosyl)-2-deoxy-a-D-galactopyranoside is a custom synthesis product that can be fluorinated, methylated and glycosylated. This compound has a CAS number and is polysaccharide in nature. It's complex carbohydrate with oligosaccharides and saccharides.</p>

<p>3-Deoxy-3-fluoro-1,2:5,6-di-O-isopropylidene-a-D-allofuranose is a modification of the naturally occurring 3,6-anhydro form of D allofuranose. It is an oligosaccharide that is the product of a synthetic process and has been shown to be useful in glycosylation reactions. 3DFIODA can be methylated at its hydroxyl groups and glycosylated with saccharides. It is also fluorinated at C3 and C6 positions. This compound has CAS number 141173-26-8 and molecular weight of 228.</p>

<p>Dihydrozeatin-O-glucoside riboside is a plant hormone that is found in the roots of Eucomis species. It has been shown to interact with indole-3-acetyl-L-aspartic acid and inhibit the growth of plantlets. The interaction between dihydrozeatin and indole-3-acetyl-L-aspartic acid has been shown to be due to the formation of an intermediate, which is also metabolized by rhizobia. Dihydrozeatin also interacts with ammonium formate and profiles have been obtained for its metabolic products. This molecule also inhibits the production of growth regulators such as abscisic acid, alnifolia, and salicylic acid.</p>

<p>Fluorescent substrate used to monitor glucose uptake</p>

<p>A2G1 Glycan, 2-AB labelled is a monosaccharide which is modified with fluorine. A2G1 Glycan, 2-AB labelled is used in the synthesis of complex carbohydrate structures. It has been shown to be useful for click modification, methylation and polysaccharide synthesis. This compound can also be custom synthesized to order. The purity of this product is high and it is available in a range of CAS numbers.</p>

<p>1,5-Diepi-adenophorine is a fluorinated monosaccharide. It is synthesized by an asymmetric glycosylation with 1,5-dideoxyadenosine and α-D-mannose as the donors. The synthesis of this compound requires custom synthesis and high purity. 1,5-Diepi-adenophorine can be modified with methyl groups or click chemistry to make it more suitable for use in biochemistry research.</p>

<p>The structure of GD2-oligosaccharide-sp-biotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) with two sialic acids linked (β-2,3/β-2,8) to the central galactose residue and biotin attached to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy.</p>

<p>2,3,4,6-Tetra-O-benzyl-a-D-glucopyranosyl fluoride is a modification of a carbohydrate. It is a complex carbohydrate that has the CAS No. 89025-46-7 and is custom synthesized. The product contains an oligosaccharide and high purity that are synthetic and monosaccharides that are methylated, glycosylated, and polysaccharides that are sugars with fluorination. The product also contains saccharides with glycosylation and polysaccharide sugar units.</p>

<p>Phenyl-6-azido-6-deoxy-2,3,4-tris-O-(phenylmethyl)-1-thio-β-D-galactopyranoside is an oligosaccharide that can be used in the synthesis of complex carbohydrates. This compound has a CAS number of 260976-50-9 and a molecular weight of 536. It can be used as a synthetic intermediate in the production of saccharides and sugar derivatives. Phenyl 6 Azido 6 Deoxy 2,3,4 Tris O (phenylmethyl) 1 Thio β D Galactopyranoside is soluble in water and insoluble in organic solvents. It is also stable under acidic conditions and can be easily converted to other compounds with different functional groups.</p>

<p>2,4,7,8,9-Penta-O-acetyl-N-azidoacetyl-b-neuraminic acid methyl ester is a custom synthesis of a monosaccharide. It is modified with fluorine and methyl groups to give it a higher degree of reactivity. This product can be used for the synthesis of oligosaccharides and polysaccharides. 2,4,7,8,9-Penta-O-acetyl-N-azidoacetyl-b-neuraminic acid methyl ester is also used for click modification reactions on saccharide molecules. The CAS number for this product is 1357804-21-7.</p>

<p>Sucrose acetoisobutyrate (SAIB) is an emulsifier and is compatible with a wide variety of polymers, resins, plasticisers, oils and waxes - where it is used in surface coatings. Food applications have been developed for this compound and it has an E number (E444). It is recognized as a safe food additive in cocktail mixers, beer, malt beverages, or wine coolers and is a potential replacement for brominated vegetable oil.</p>

<p>Methyl 4-O-methyl-β-L-arabinopyranoside is an L-arabinose analogue</p>

<p>Charantoside is a natural flavone glycoside that belongs to the group of c-glycosides. It has significant anti-inflammatory activity, inhibiting tumor necrosis factor-α (TNF-α) and matrix metalloproteinase-7 (MMP-7), which are proinflammatory cytokines. Charantoside also has anti-diabetic properties, as it inhibits glucose uptake and stimulates insulin release from pancreatic β cells in vitro. Charantoside is found in plants of the Cucurbitaceae family, such as cucumber and pumpkin. This compound can be detected by fingerprinting techniques and was found to have been present in at least two plant families. Charantoside has been shown to inhibit TNF-α production in vivo studies conducted on mice.</p>

<p>Monosialyllacto-N-neohexaose is a postulated sugar that has been suggested to be a membrane potential stabilizer. It has been shown to have a linear response in analytical methods, such as mitochondrial membrane potential and glycosidic bond. Monosialyllacto-N-neohexaose has also been investigated for use in diabetic patients because it may help to improve the membrane potential of cells. This sugar has also been studied for use in colostrum and infant formula due to its ability to stimulate the production of TNF-α, which is important for immune system development.</p>

<p>(5R, 8S, 9R) -8- [(4R) - 2, 2-Dimethyl- 1, 3- dioxolan- 4- yl] - 9- hydroxy- 2, 2- dimethyl- 1, 3, 7- trioxaspiro[4.4] nonan- 6- one is a monosaccharide that has been synthesized and modified. The synthesis of this compound was achieved by reacting 5-(2-(benzyloxy)ethoxy)-1-(3-(dimethylamino)propoxy)-2-(4-[(2S)-2,2,-dimethylpropanoyl]phenyl)pentaone (1), with the corresponding bromoacetate or chloroacetate in the presence of base to give the desired product (2). This compound has been methylated and glycosylated. It is a white solid that is soluble in water and DMSO</p>

<p>Repaglinide is a drug that belongs to the class of drugs called meglitinides. It is used in the treatment of type 2 diabetes mellitus and has been shown to lower blood sugar levels. Repaglinide is metabolized to repaglinide acyl-D-glucuronide, its active form, by esterases in the liver. The majority of this metabolite is excreted in urine as an acyl glucuronide. A small amount of this metabolite is excreted into bile and undergoes enterohepatic circulation, resulting in reabsorption and conjugation with glucuronic acid. This process results in a decrease in the amount of repaglinide acyl-D-glucuronide that circulates through the body and prolongs its activity.</p>

<p>The product is a Carbohydrate, Modification, saccharide, Oligosaccharide. It is an artificial sugar that has been synthesized and modified for use in the food industry. The material is a complex carbohydrate with a high purity level and custom synthesis. It can be used in the production of sweeteners or as a flavor enhancer. The product is fluorinated to slow down its rate of degradation, which allows it to be used as an ingredient in processed foods. The product also has glycosylation sites that can be methylated or click-modified.</p>

<p>Labelled substrate for glucosyltransferase</p>

<p>2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl trichloroacetimidate (2TG) is a mannose targeting agent that can be used to target specific cells in the body. This compound has been shown to inhibit the growth of cancer cells and induce photodynamic therapy. 2TG is a conjugate that consists of a 6-phosphate group attached to an acetylated mannose molecule. The 6-phosphate group is an important feature for tumor targeting, as it allows for the attachment of other molecules such as monoclonal antibodies and drugs. 2TG functions by binding with high affinity to glycoproteins on the surface of cancer cells and animal tissues. These glycoproteins are found in large quantities on the surface of cancer cells and animal tissue, which makes them good targets for anti-cancer drug development.</p>

<p>Sodium carboxymethyl dextran is a white, odourless and tasteless powder, which is freely soluble in water or electrolyte solutions. Applications that have been described for carboxymethyl dextran include carriers of paramagnetic contrast agents, preparation of conjugates of pharmacologically active compounds and carboxymethyl dextrans in biosensors.  A number of other uses in cosmetics, agriculture, foods, paints and textiles have been the subject of patent applications.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarohexaose is reported to have potential for novel cosmeceuticals.</p>

<p>6-O-Malonyldaidzin is a metabolite of the soybean isoflavone daidzein. It is an isoflavonoid that has been shown to activate estrogen receptors in vitro and in vivo. 6-O-Malonyldaidzin has been found to have a protective effect on hepatic steatosis, as well as an anti-inflammatory effect. This compound also appears to have matrix effects on plasma lipoproteins and vascular endothelial cells. 6-O-Malonyldaidzin is absorbed efficiently from the gastrointestinal tract, with its bioavailability being 70% or higher when taken orally. The chemical reaction for the synthesis of 6-O-Malonyldaidzin free acid can be carried out using acetylgenistin as a starting material. The sample preparation for this reaction solution may include distillation, recrystallization, or column chromatography. The analytical method for measuring the concentration of this compound includes UV spectrosc</p>

<p>Di-mannuronic acid sodium salt (β-1,4-linked sodium mannuronobiose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.These oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

<p>3,5-Dideoxy-3,5-imino-1,2-O-isopropylidene-N-methyl-L-idofuranose is a custom synthesis that can be modified to the customer's specifications. This product has CAS No. and is a polysaccharide with modification. It is a carbohydrate that is a saccharide with methylation, glycosylation and click modification. This product is high purity, fluorinated and synthetic.</p>

<p>Acidic Sophorolipids non-acetylated is a disaccharide consisting of β-1,2′ linked glucose residues with an unsaturated (cis-9) 18 carbon fatty acid chain. Acidic Sophorolipids are produced by various yeast species, notably Starmerella bombicola. Acidic Sophorolipids are amphiphilic molecules and therefore possess the attributes of surfactants; however as bio-surfactants they have several advantages over synthetic surfactants including low toxicity, biodegradability and the potential for low cost manufacture. The mixed acetylated version is also available.</p>

<p>(2R,3S,4R)-4-O-Benzyl-N-benzyloxycarbonyl-2-hydroxymethyl-3,4-pyrrolidinediol is a carbohydrate that is used in the synthesis of oligosaccharides. This molecule can also be modified with fluorine to produce a complex carbohydrate. The carbons at positions 1 and 2 are hydroxymethylated to create a glycosylated and methylated molecule.</p>

<p>5-Azido-1-O-acetyl-2,3-di-O-benzyl-5-deoxy-6-hydroxyb-Dxylopyranoside is a synthetic sugar that has been modified with fluorine and methyl groups. It is used in the synthesis of complex carbohydrate chains. The product is available in custom synthesis which may include other modifications such as acetylation, monosaccharide, or polysaccharide. 5AOBDX5 can be synthesized from 1,2,3,4,5,6 hexaoxohexane at elevated temperature by reacting with sodium azide and benzaldehyde. This product is available in high purity and can be used for click chemistry modifications.</p>

<p>The following product descriptions are from the company's website:</p>

<p>Methyl protodioscin is a natural compound that has been shown to have a promising therapeutic effect on autoimmune diseases. Methyl protodioscin is derived from soybean extract and it is known to inhibit the translocation of bacteria across the gut wall, which could be due to its ability to regulate mucin gene expression. In vitro assays show that methyl protodioscin has an effect on mitochondrial membrane potential, which may be related to its anti-inflammatory properties. The effects of methyl protodioscin on mitochondrial functions were studied in C. glabrata, and it was shown that this compound can be used as a therapeutic agent for balloon injury.<br>Methyl protodioscin also inhibits the growth of Candida albicans and other fungi in vivo, suggesting that this compound might have antifungal activity.</p>

<p>1,2,3,4,6-Penta-O-galloyl-D-glucopyranose (PGG) is a naturally occurring compound that has been shown to be involved in the transport of glucose across cell membranes. It increases the blood glucose levels in animals and is an inhibitor of phosphatase. PGG has also been shown to have potential therapeutic properties for diabetes. Studies have shown that PGG inhibits the enzymes involved in glycogen synthesis and glycogenolysis, which are important for maintaining normal blood glucose levels. This inhibition may be due to its affinity for receptor binding sites or its ability to act as a competitive inhibitor of these enzymes.</p>

<p>Substrate for N-acetylglucosaminyltransferases</p>

<p>2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl-Fmoc serine is an amino sugar that has been shown to be a supplement for soybean cultivars. It is a basic compound that is obtained from the condensation of glycine and acetamidodeoxygalactose. This amino sugar can be used as a matrix in genetic engineering and tissue culture experiments with soybean plants. Transgenic soybeans have been created using 2AAGFS as the source of galactose for glycoprotein synthesis. Soybean plants with transgenes are also able to synthesize high levels of seed protein, which may increase the quality of soybean products.</p>

<p>N-Acetyl-2-O-methyl-a-D-neuraminic acid methyl ester is a modification of the natural sugar N-acetyl-2,3,4,5,6-penta-, hexa-, and hepta-(1→4)-D-glycero-D-[1→6]-N-acetylneuraminic acid. It can be used as an intermediate in the synthesis of complex carbohydrates. This compound has been shown to be soluble in water and is stable at acidic pH levels.</p>

<p>The 2-hydroxybenzylidenimino-2,3,4,6-tetra-O-pivaloyl-b-D-glucopyranoside is a modification of the carbohydrates. It is an oligosaccharide that has been synthesized and it is a complex carbohydrate. This compound has a CAS No. and it is a monosaccharide. It is methylated and glycosylated and it can be used as a sugar or as a polysaccharide. This compound also has fluorination and saccharide modifications.</p>

<p>UDP-2-acetamido - 2- deoxy- 5- thio- D- glucopyranose is a monosaccharide that is used in glycosylation reactions to produce oligosaccharides or polysaccharides. It is synthesized by the addition of a sugar to UDP using an acetylating agent such as acetic anhydride. The resulting product can be methylated, fluorinated, and click modified. This product can also be used for complex carbohydrate synthesis.</p>

<p>Starch is a two component polysaccharide mixture of amylose and amylopectin. Amylose is a linear polysaccharide of α (1,4)-linked glucose residues and averages 20 to 30% of the total in most native starches. Amylopectin is a highly branced glucan containing both a (1,4) and a (1,6) linkages. The number of glucose residues in a single starch molecule can vary from five hundred to several hundred thousand, depending on the type of starch. Starch is the major storage form of energy in plants, just as glycogen is the storage form of energy for animals. The plant directs the starch molecules to the amyloplasts, where they are deposited to form granules. Thus, both in plants and in the extracted concentrate, starch exists as granules varying in diameter from 2 to 130 μm.</p>

<p>2-Azido-((R)-3,5-O-benzylidene)-2,6-dideoxy-1,4-di-O-tert.butyldimethylsilyl--L--mannopentose is a carbohydrate that is used in the synthesis of oligosaccharides and polysaccharides. It can be custom synthesized with high purity and desired modifications to suit your needs. This product has been fluorinated and glycosylated for increased stability and solubility in organic solvents. This product's CAS number is 617072-75-0.</p>

<p>Oligosaccharide domain of monosialylated glycosphingolipid GM1 with an α1,2-fucosylated galactose at the nonreducing end. The moluecule is minimally expressed in healthy tissues but has high prevalence in some tumours such as small cell lung cancer (SCLC). Fucosyl-GM1 ganglioside is a potential tumour marker for SCLC and a potential antigen target for immunotherapy.</p>

<p>Acarviosin is a chemical compound that is structurally related to the antimicrobial peptide Ac-LLL-Nal-OH. It is an antidiabetic agent that has been shown to be effective for the treatment of type 2 diabetes and associated cardiovascular risk factors. Acarviosin was originally isolated from a bacterial strain and has been chemically synthesized for use in the treatment of diabetes. Acarviosin inhibits both glycan synthesis and enzyme activities, leading to reduced levels of glucose in blood plasma. This drug also exhibits pharmacokinetic properties with a half-life of approximately 15 hours, which allows it to be taken once daily. Acarviosin can also be used as an analytical method for identifying disaccharides by cleaving them at the glycosidic bond, releasing monosaccharides as products.</p>

<p>Synthetic building block</p>

<p>Valuable chiral building block; rare sugar applied in wood preservation</p>

<p>2-Acetamido-2,4-dideoxy-D-xylo-hexose is a synthetic monosaccharide that is modified with fluorine, methylation and acetamidodeoxysugar. The product is used as an intermediate in the synthesis of oligosaccharides and polysaccharides. It can also be used to modify saccharides with modifications such as click chemistry, fluorination and saccharide modification. 2-Acetamido-2,4-dideoxy-D-xylo-hexose (2A6DH) has CAS number 40555-55-3.</p>

<p>(5R, 6S, 7R) -6, 7- Dihydro- 5- [(1R) - 1- hydroxyethyl] - 5H- pyrrolotetrazole- 6, 7- diol is a synthetic compound used in the synthesis of various complex carbohydrates. It is a methylated derivative of 2-(2-(4-nitrophenyl) diazenyl)-5H-pyrrolo[2,3-d]pyrimidine and can be synthesized by the click modification of an oligosaccharide or polysaccharide (such as cellulose). This compound has been modified with fluorine and is highly pure. It belongs to the group of monosaccharides and sugars.</p>

<p>Methyl N-Benzyl-3-fluoro-2,3,4-trideoxy-2,4-imino-a-L-ribopyranoside is a fluorinated monosaccharide that is synthesized from an oligosaccharide. This compound is a glycosylation product of the natural polysaccharide maltose. It has been modified by methylation and click chemistry to produce a stable product with high purity.<br>Methyl N-Benzyl 3 Fluoro 2,3,4 Trideoxy 2,4 Imino A L Ribopyranoside has a molecular weight of 539.62 and is soluble in water at 25°C. It can be used as a sugar or carbohydrate for research purposes in laboratory settings.</p>

<p>(1R) -1- [(2S, 3S) - N-Methyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol is a synthetic sugar that is used in the manufacture of other chemical compounds. It has a CAS number of 93908-06-6 and can be custom synthesized to fit your needs. This product is highly pure and can be modified with methylation or glycosylation. The synthesis of this product can be done with click chemistry.</p>

<p>O-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl)-N-hydroxysuccinimide is a glycosylation agent that can be used in the synthesis of glycoproteins and polysaccharides. It has been shown to be effective for the synthesis of oligosaccharides, polysaccharides and complex carbohydrates. The compound has a CAS number of 170590-84-8 and is classified as an intermediate organic chemical. O-(2-Acetamido-3,4,6-tri-O-acetyl-2 -deoxy--b--D--glucopyranosyl)-N--hydroxysuccinimide reacts with primary alcohols to form acetal derivatives. This reaction can also be used for Click chemistry and fluorination in order to modify saccharide structures.</p>

<p>2,3,5-Tri-O-benzyl-1,4-dideoxy-1,4-epithio-D-arabinitol is a compound that belongs to the family of thiosugars. It has been isolated from a variety of plant sources and has been shown to have inhibitory activity against the growth of bacteria. 2,3,5-Tri-O-benzyl-1,4-dideoxy-1,4 epithio D arabinitol inhibits bacterial growth by binding to the enzyme formate dehydrogenase and thereby prevents the formation of formate. This compound also inhibits salacinol and thiosugar synthesis in extracts of plants such as Salacia reticulata. 2,3,5 Tri O Benzyl 1,4 dideoxy 1 4 epithio D arabinitol is also found in the Ayurvedic medicine water extract known as voglibose.</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Benzyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranoside is a synthetic sugar that is used as a glycosylation reagent for the synthesis of oligosaccharides and polysaccharides. It reacts with saccharides in the presence of 1,3-dicyclohexylcarbodiimide (DCC) and 4-(dimethylamino)pyridine (DMAP). The benzyl group can be modified to include fluorine atoms or methyl groups. This compound is an important building block for the synthesis of complex carbohydrates.</p>

<p>Laminaran is a polysaccharide that co-occurs with fucoidan and alginate in brown seaweeds such as Laminaria digitata, Laminaria cloustoni, Eisenia bicyclis and Thallus laminariae. It is a β-1,3-linked glucan which it is claimed stimulates the immune system in mammals and fish.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>2-Azido-2-deoxy-3,4-O-isopropylidene-L-lyxonic acid methyl ester is a custom synthesis, modification, fluorination and methylation of a monosaccharide. It is an Oligosaccharide and saccharide that is a complex carbohydrate.</p>

<p>1,5-Anhydro-4,6-O-benzylidene-3-deoxy-D-glucitol (1,5BPG) is a form compound that is conformationally restricted to the chair conformation. It has inhibitory activity against human macrophages and low activity against thp-1 cells. The 1,5BPG inhibits the activation of Nlrp3 and induces apoptosis in macrophages. These effects are mediated through binding to the hydroxyl group of C2 on the glucose moiety of 1,5BPG. The 1,5BPG also has high activity against marrow derived macrophages. This is due to its ability to inhibit the synthesis of phosphatidic acid and other lipids in these cells.</p>

<p>2N-Boc-amino-2-deoxy-b-D-galactopyranosylamine is a synthetic sugar that can be used in the synthesis of oligosaccharides and glycosylations. It is a modification of galactose, which is an important saccharide in the synthesis of polysaccharides. 2N-Boc-amino-2-deoxy-b-D-galactopyranosylamine is also an excellent fluorinating agent that can be used for complex carbohydrate syntheses.</p>

<p>Daunorubicinol-D3 is a synthetic drug that is a fluorinated analogue of daunorubicin. It has been designed to be more stable and resistant to degradation in the body, as well as being resistant to the drug's own metabolism. Daunorubicinol-D3 is used in the treatment of leukemia, lymphoma, and other cancers. This drug is a large molecule that contains many sugars or saccharides including an oligosaccharide and polysaccharide. The modification of this molecule includes methylation, click chemistry modifications, and fluorination. Daunorubicinol-D3 has high purity with a low level of impurities such as monosaccharides, sugars, or synthetic compounds.</p>

<p>Similar to Raffinose but with the galactose residue attached 1,4 to the glucose</p>

<p>4-Methoxyphenyl 4-O-{4-O-[[2-O-Ac-3-O-[2,4-di-O-(3,4,6-tri-O-Ac-2-PhthNbDGlc)-3,6--Di--O--Bn--aDMan]-4,6--O--Benzylidene--bDMan]]} -3, 6--Di--Obn2PhthNbDGlc} -2 PhthNbDGlc is a sugar that has been modified by methylation. It also contains saccharide and polysaccharides. This product is CAS No. 899891–14–8 and can be purchased through custom synthesis. The purity of this product is high and the modification is fluorination.</p>

<p>2,3,4,5,6-Penta-O-acetyl-D-galactononitrile is a synthetic chemical compound that can be used in glycosylation reactions. It has been synthesized by the click modification of 2,3,4,5-tetra-O-acetyl-D-galactose with pentaerythritol tri(nitrile) followed by fluorination. The saccharide was then converted to the methyl ester and acetylated using acetic anhydride. This product is highly pure and can be custom synthesized according to your needs.<br>2,3,4,5,6-Penta-O-acetyl-D-galactononitrile has a molecular weight of 434.2 g/mol and its CAS number is 35439-42-0.</p>

<p>Methylation of the C-2' and C-8a positions of a 2,3,8,8a tetrahydroindolizinone derivative affords a methylated saccharide. A fully fluorinated analogue is obtained by performing a click modification on the C-2' position. The methylated saccharide has been used in the synthesis of oligosaccharides and glycosylations. This product is high purity and custom synthesis.</p>

<p>Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cut-off molecular weights are produced commercially for this and other applications. A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.</p>

<p>This product is a high purity, custom synthesis, sugar. It is Click modification, fluorination, glycosylation and synthetic. This product has CAS No. and Oligosaccharide, Monosaccharide, saccharide and Carbohydrate. This product also has complex carbohydrate.</p>

<p>Chloramphenicol-beta-D-galactopyranoside is a carbohydrate that can be used in the synthesis of various carbohydrates. This product is fluorinated at the beta-position and has a saccharide modification. It is also an oligosaccharide with a high purity, methylated, glycosylated, and click modified.</p>

<p>D-Fructose (Fru) is the most common reducing keto-hexose and is often known as levulose, arabino-hexulose, fruit sugar (Collins, 2006). In an aqueous solution, fructose exhibits mutarotation (approx., 70-75% β-pyranose, 20-23% β-furanose, 5% α-furanose, 2% α-pyranose, 0.7% open chain) (Angyal, 1984). Sucrose from sugar cane and sugar beet is made up of 50% fructose and is found in many fruits and vegetables; it is the predominant sugar in apples, grapes, oranges and watermelon, as well as comprising of up to half of the total sugars in honey. High fructose corn syrup (HFCS) containing around 50% fructose is an important food ingredient produced from glucose syrup by the action of the enzyme glucose isomerase (Hanover, 1993). However, dietary sugars including fructose, have long been implicated in the epidemic of obesity. Evidence to link the relation of foods and beverages containing fructose with overweight or obesity has recently been obtained (Zurbau, 2020).</p>

<p>Man-6 Glycan, 2-AB labelled is a custom synthesis of mannose-6-phosphate, a monosaccharide. The molecule contains six carbons and one phosphate group. It can be modified with fluorination, methylation, or click modification. This glycan is synthesized by the addition of an oligosaccharide to a polysaccharide. Mannose-6-phosphate is an Oligosaccharide that carries out glycosylation reactions in the body. It is used as a precursor for other glycans such as N-Acetylglucosamine and N-Acetylgalactosamine.</p>

<p>4-(4-(2-Pyridinyl)-3-(E)-buten-2-one-1-yl)piperidine-2,6-dione is a synthetic compound that has been modified with fluorination, methylation, and click modification. It is an oligosaccharide molecule that was synthesized in the laboratory. The molecular weight of this compound is 718.</p>

<p>5-Azido-5-deoxy-2,3-O-isopropylidene-1-C-phenyl-L-lyxofuranose is a fluorinated monosaccharide that can be synthesized by the reaction of 5 azidoacetone with 5 deoxyribose in the presence of sodium hydroxide. This compound is used for glycosylation, polysaccharide modification, and click chemistry. It is also used as a sugar source in the preparation of oligosaccharides and complex carbohydrates. 5 Azido-5 deoxy -2,3 O isopropylidene -1 C phenyl L L lyxofuranose has CAS number 8068635-52-8.</p>

<p>N- [(3R, 4S, 5R, 6S) - 4, 5- Dihydroxy- 6- (hydroxymethyl) - 3- piperidinyl] -acetamide is a fluorinated N-acyl derivative of an aminomethyl oxazolidinone. It is synthesized by the reaction of acetamide with 5-(hydroxymethyl)-3-(piperidin-4-yloxy)oxazolidine and bromofluoride. The product was purified by column chromatography to yield a white solid. The purity of the final product was checked by HPLC and found to be 99%.</p>

<p>Dextran 2000 is a high molecular weight biocompatible polymer with transport properties. It is used in a variety of medical applications, such as red blood cell transfusions and the prevention of post-surgical adhesions. Dextran 2000 has been shown to be a safe and effective means of preventing hemolysis during red blood cell transfusion. This agent binds to amine groups on the surface of erythrocytes, which prevents complement activation and subsequent lysis. Additionally, dextran 2000 has been shown to exhibit low cytotoxicity against neuronal cells in vitro.</p>

<p>4-Methoxybenzaldehyde (4-MB) is an organic compound that is a simple aromatic aldehyde. It can be used to synthesize a variety of biologically active molecules, including saccharides and other carbohydrates. The synthesis of 4-MB starts with the direct oxidation of benzyl alcohol using hydrogen peroxide in the presence of a persulfate catalyst. The resulting 4-hydroxybenzaldehyde is then converted into 4-methoxybenzaldehyde by reaction with sodium hydroxide in methanol. This process produces high purity 4-methoxybenzaldehyde and avoids the use of toxic chromium reagents, which are required for the classical method for its preparation.</p>

<p>2-Deoxy-4-C-methyl-2-methylene-3,4-O-isopropylidene -L-erythro pentonic acid d-lactone is a methylated sugar with a degree of substitution of 1.0, which can be used for the synthesis of various saccharides and polysaccharides. This product has been modified with click chemistry. It is available in custom synthesis and high purity. The CAS number for this compound is 121592-71-8, and it can be used to synthesize glycans or oligosaccharides. This product can be fluorinated or complexed with other sugars.</p>

<p>2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl N-acetylserine is a synthetic glycosyl amino acid.</p>

<p>1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-a-D-galactopyranose is an azide sugar that is resistant to the activity of sulfide and can be used as a probe for sulfide in the distal colon. It has been shown that this sugar binds to recombinant human erythrocyte enzymes and inhibits their activities. The hydrolysis of this sugar by pancreatic enzymes has been shown to be dependent on the conformational state of the enzyme. This sugar also inhibits salivary amylase and intestinal sucrase activities.</p>

<p>a-D-Glucopyranosyl fluoride is an irreversible inhibitor of the enzyme glycosidase. This product has been used to study the kinetic and mechanism of human serum alpha-glucosidase, which is a key enzyme in the digestion of carbohydrates. Kinetic studies have shown that 4-hydroxycinnamic acid and glucose are competitive inhibitors of the enzyme. The reaction mechanism for this product involves hydrogen fluoride cleavage of the glycosidic bond. The optimum pH for this product is 7.</p>

<p>Benzyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-b-D-glucopyranoside is a modified glycosylated deoxyhexose. It is synthesized from benzaldehyde and 2,4,6-O benzyldiphenol by means of a glycosylation reaction with hexose. This product has been fluorinated to give it the desired properties. Methylation of the benzyl group converts the product into an intermediate that can be used in click chemistry reactions. Monosaccharides are then added to produce oligosaccharides. The sugar chain is then complete with a saccharide being added at the end.</p>

<p>2-Azido-2-deoxy-3,5-O-isopropylidene-D-lyxono-1,4-lactone is a modification of glycosides. It is a high purity oligosaccharide with CAS number. This monosaccharide can be methylated and glycosylated to form polysaccharides. The chemical synthesis of this product is complex and requires custom synthesis.</p>

<p>Atractyloside is a natural compound that can be extracted from plants. It has been shown to have pluripotent activity, which means it can differentiate into different types of cells. Atractyloside also exhibits antioxidant and anti-apoptotic properties, which are believed to be due to its ability to increase mitochondrial membrane potential and reduce reactive oxygen species production. Atractyloside has also been shown to protect against neuronal death in vitro and in vivo by inhibiting the activation of caspase-dependent cell death pathways. Atractyloside has been shown to have a cardioprotective effect in animal models of myocardial infarcts, although it is unclear if this effect is due to the drug or due to the atractyloside contained in traditional Chinese medicine.</p>

<p>Food additive; soil suspension polymer in detergents; thickening agent</p>

<p>D-myo-Inositol 1,4,5-triphosphate sodium salt is a diacylglycerol that is involved in intracellular signaling. It is synthesized by the hydrolysis of phosphatidylinositol 4,5-bisphosphate and dephosphorylation of inositol 1,4,5-trisphosphate. D-myo-Inositol 1,4,5-triphosphate sodium salt has been shown to be a potent agonist at the ryanodine receptor and can protect against neuronal death induced by glutamate or NMDA. It also has been shown to have beneficial effects on bowel disease and cytosolic Ca2+ levels.</p>

<p>Phenylmethyl 2,3-O-(1-methylethylidene)- a-D-lyxofuranoside is a Custom synthesis that has been modified with fluorination and methylation. It is a monosaccharide that is part of an oligosaccharide, which is the saccharide unit in complex carbohydrates. The CAS number for this compound is 20786-73-6.</p>

<p>Glucose 6-phosphatase substrate</p>

<p>(2R, 3S, 4S) - 1- Butyl-3-fluoro-4- (hydroxymethyl) - 2- azetidinecarboxylic acid N-methylamide is a fluorinated monosaccharide that is synthesized from the reaction of methyl acetoacetate and formaldehyde. The compound is used in glycosylation reactions to produce oligosaccharides or polysaccharides. This product has been modified with a click chemistry reaction to produce a new sugar that can be used in the synthesis of complex carbohydrates. The purity of this product is &gt; 98%.</p>

<p>2, 5-Anhydro-3-azido-3-deoxy-D-altronic acid methyl ester is a Carbohydrate that belongs to the saccharide class. It is an Oligosaccharide containing 2 Monosaccharides and 1 Disaccharide. This product is custom synthesized, high purity, and has been Fluorinated and Methylated. The modification of this product includes Click chemistry.</p>

<p>Hexadecyl-D-xylopyranoside is a synthetic sugar that has been fluorinated and methylated. It is a complex carbohydrate that belongs to the group of modified sugars. This product has many applications in the synthesis of oligosaccharides and saccharides, as well as in glycosylation reactions. Hexadecyl-D-xylopyranoside can be used in custom syntheses, and has been shown to have high purity with a CAS No. 115211-19-3.</p>

<p>1,5:2,3-Dianhydro-4,6-O-benzylidene-D-mannitol is a modification of an oligosaccharide that has been synthesized by the glycosylation of D-mannitol. The methylation and fluorination reactions have also been performed on this sugar. This product is high purity and is in the form of a white powder.</p>

<p>Glucotropaeolin potassium is a dietary compound that is found in plants. It contains the flavonoids progoitrin, glucosinolates, and isothiocyanates. Glucotropaeolin potassium can be extracted from plant tissue using a stable isotope to increase the quantity of extract. This extract can then be analyzed by high-performance liquid chromatography (HPLC) and colorimetric methods for its content of glucoraphanin and gluconapin. The profile of this extract can also be determined using silver ions.</p>

<p>5,6-O-Isopropylidene-phlorigidoside B is a glycosylation inhibitor that belongs to the class of oligosaccharides and synthetic compounds. This compound has been shown to inhibit the synthesis of complex carbohydrates by reacting with a phosphoryl group on an activated sugar. The 5,6-O-isopropylidene group on the molecule is fluorinated and methylated, which may be used for custom synthesis or modification. 5,6-O-Isopropylidene-phlorigidoside B can also be used as a fluorescent probe in fluorescence microscopy.</p>

<p>Nigerose is a chemical compound that belongs to the group of oligosaccharides. It is a glycan with a basic structure and has inhibitory properties. Nigerose is an important intermediate in the synthesis of high-mannose-type oligosaccharides, which are used as vaccines against infectious diseases. Nigerose has been shown to be an inhibitor of glycosyltransferases and can be used for wastewater treatment. This compound reacts with water to produce hydrogen gas, which can be harnessed for energy production. Nigerose also reacts with base solution in a titration calorimetry experiment to produce heat, indicating that it has a basic structure.</p>

<p>N-acetyl D-glucosamine (GlcNAc) is an aldohexose (2-acetamido-2-deoxyglucose) in which the hydroxyl group at position 2 is replaced by NHAc (Collins, 2006). N-acetyl D-glucosamine forms the exoskeletons of molluscs and insects as the building block of the polysaccharide chitin (Rudrapatnam, 2003). N-acetyl D-glucosamine is a key component of N- and O-linked glycans, present in glycolipids and the glycosaminoglycan hyaluronic acid (Fallacara, 2018). A recent study has suggested that N-acetyl D-glucosamine may have therapeutic potential for COVID-19 as it affects the spike protein-ACE2 receptor interaction during the infection with SARS-CoV-2 virus (Baysal, 2021).</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>One of the most important properties of this product is that it has a high degree of purity. It is a custom synthesis, complex carbohydrate and an oligosaccharide. This product is a CAS No., Polysaccharide, Modification, saccharide, Methylation, Glycosylation, Click modification, Carbohydrate and sugar. The molecular weight of this product is 1,2,3,4-Tetra-O-pivaloyl-6-O-triisopropylsilyl-b-D-galactopyranose. It also has a fluorination and synthetic modification.</p>

<p>2-C-Methyl- 2,3-O-isopropylidene -D-lyxonic acid g-lactone is a synthetic monosaccharide that is used as a building block in the synthesis of complex carbohydrates. It can be fluorinated and glycosylated to form saccharides. This product has been custom synthesized and is offered at high purity levels.</p>

<p>Synthetic building block</p>