Glycoscience

Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. This product has a 13C heavy-label and so can be used in applications such as metabolic tracing and quantitative mass spectrometry.

Food additive, applied in pharmaceuticals and beauty products.

(1S) -1- [(2S, 3R) - 3- Hydroxy- 1- (2-hydroxyethyl) - 2- azetidinyl] -1, 2- ethanediol is a carbohydrate that is modified by fluorination and methylation. This product is custom synthesized to your specifications. It has been shown to be effective in glycosylation reactions and click chemistry.

Hybrid Glycan, 2-AB labelled is a custom synthesis of a high purity glycosylation product. This synthetic oligosaccharide includes saccharides that are labelled with 2-AB. The modification is Click chemistry and provides a method for attaching the label to the sugar molecule. This product is not found in nature or existing in cells or organisms. It is used as a research tool in immunology, cell biology, and structural biology applications.

Applications 4,6-O-Benzylidene-N-acetyl-D-galactosamine (cas# 420118-03-2) is a compound useful in organic synthesis.

Stability Temperature Sensitive, Hygroscopic - Store Refridgerated
Applications An intermediate in the synthesis of PugNAc (Cat. No. A15725), an inhibitor of glucosamidase.
References Beer, D., et al.: Helv. Chim. Acta., 73, 1918 (1990), Horsch, M., et al.: Eur. J. Biochem., 197, 815 (1991), Horsch, M., et al.: J. Enzyme Inhib., 7, 47 (1993),Horsch, M., et al.: Eur. J. Biochem., 237, 476 (1996),

Applications Spiramycin Embonate is an antibiotic that is used in biological studies in the role of multidrug resistance of Strenotrophomonas maltophilia.
References Huang, Y., et al.: J. Antimicrob. Chemother., 68, 1987 (2013); Poole, K., et al.: Mol. Microbiol., 21, 713 (1996)

Impurity Capecitabine 3-O-BDR Impurity (USP)
Applications Capecitabine (C175650) impurity. Capecitabine 3-O-BDR Impurity (USP).

Applications Trigalacturonic Acid, is the product of polygalacturonic acid degradation. The mixture of Oligogalacturonic Acids has shown to have shoot growth in cockscomb (Celosia argentea L.) seedlings.
References Suzuki, T., et al.: J. Plant Growth Reg., 21, 209 (2003);

Stability Hygroscopic
Applications 3-O-(α-D-Galactopyranosyl)-D-galactose (cas# 13168-24-6) is a compound useful in organic synthesis.
References Abramenko, I.V., et al.: Tsitologiya, 35 (5), 91 (1993), Kelly, R.F., et al.: Mol. Microbiol., 10 (3), 615 (1993), Stortz, C.A., et al.: J. Carbohydr. Chem., 13 (2), 235 (1994), Neethling, F.A., et al.: Transplantation, 57 (6), 959 (1994)

Applications 2-Acetamido-2-deoxy-N-[N-(benzyloxycarbonyl)-ε-aminocaproyl]-β-D-glucopyranosylamine (cas# 56146-89-5) is a compound useful in organic synthesis.

Applications Propylene Glycol β-D-Glucopyranosiduronic Acid Benzyl Ester 2,3,4-Triacetate-d6 s an intermediate in the synthesis of Isotope labelled Propylene Glycol 2-Glucuronide which is a metabolite of propylene glycol, used in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds.
References Szczepankiewicz, B. et al.: J. Med. Chem., 49, 3563 (2006); Mateus, R. et al.: Int. J. Pharm., 444, 106 (2013);

Applications Intermediate used in the addition of protected Glucopyranuronic Acid.

An anhydro thio sugar

4-Hydroxypropofol 1-O-b-D-glucuronide is a metabolite of propofol that is found in human urine. It can be detected by chromatography and UV spectroscopy. 4-Hydroxypropofol 1-O-b-D-glucuronide has been shown to have radical scavenging activity and can be used as an analytical reagent for the validation of analytical methods. This compound has also been analysed for its cytotoxic and antiinflammatory effects on the cytosol of cultured cells, with promising results.

An anhydro thio sugar

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

The enzyme alcohol dehydrogenase, which is located in the cytosol of cells, catalyzes the conversion of ethanol to acetaldehyde. In this reaction, a hydrogen ion (H+) is abstracted from ethanol and two electrons (e-) are added to the molecule. The addition of these electrons results in the formation of a hydrogen bond between the alcohol and an electron-donating species such as water or octyl glucopyranoside. Octyl glucopyranoside is a detergent that has been used as a substrate for measuring rates of alcohol dehydrogenase. This detergent also has been shown to be effective at removing glycol ethers from biological samples.
The biochemical research on octyl glucopyranoside includes its use as an equilibrative nucleoside and its effect on bowel disease.