Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 835 products of "Antifungals"
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R406
CAS:<p>Applications R406 is a potent Syk inhibitor which affects Dectin-1-mediated signalling in mammilian cells. R406 thus acts an anti-fungal agent. Also a potential anti-leukemia agent, through modulation of sphingosine-1 phosphate receptor 1 (S1PR1).<br>References Borge, M. et al.: J. Immunol., 193, 3165 (2014); Kimura, Y. et al.: J. Biol. Chem., 289, 31565 (2014);<br></p>Formula:C22H23FN6O5·(C6H6O3S)Color and Shape:Light BrownMolecular weight:470.45 + (158.18)4-(Bromomethyl)-1-chloro-2-methoxybenzene
CAS:Controlled ProductFormula:C8H8BrClOColor and Shape:NeatMolecular weight:235.51Methyl N-Hydroxy-2-methylphenylcarbamate
CAS:Controlled ProductFormula:C9H11NO3Color and Shape:NeatMolecular weight:181.191,4-Dimethyl-5-phenyl-1H-pyrazol-3-ol
CAS:Controlled ProductFormula:C11H12N2OColor and Shape:NeatMolecular weight:188.232-[(6-Chloro-4-pyrimidinyl)oxy]-α-(dimethoxymethyl)benzeneacetic Acid Methyl Ester
CAS:Controlled Product<p>Applications 2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(dimethoxymethyl)benzeneacetic Acid Methyl Ester is an impurity of Azoxystrobin (A965150), an strobilurin fungicide.<br>References Liu H.J., et al.: J. Chin. Chem. Soc., 60, 27 (2013);<br></p>Formula:C16H17ClN2O5Color and Shape:NeatMolecular weight:352.77Mandestrobin 2-Demethyl
CAS:Controlled Product<p>Applications 2-Demethyl Mandestrobin is an intermediate used in the synthesis of Mandestrobin (M162555), which is a novel fungicide having a methoxyacetamid structure. Mandestrobin also shows safer profiles for human health and the environment.<br>References Hirotomi, D., & Kiguchi, S.: PCT Int. Appl., WO 2017026526 A1 20170216 (2017)<br></p>Formula:C18H21NO3Color and Shape:NeatMolecular weight:299.36Methyl 2-[2-[(2,5-Dimethylphenoxy)methyl]phenyl]-2-(hydroxy)acetic Acid Ester
CAS:Controlled Product<p>Applications Methyl 2-[2-[(2,5-Dimethylphenoxy)methyl]phenyl]-2-(hydroxy)acetic Acid Ester is an intermediate used in the synthesis of Mandestrobin (M162555), which is a novel fungicide having a methoxyacetamid structure. Mandestrobin also shows safer profiles for human health and the environment.<br>References Hirotomi, D., & Kiguchi, S.: PCT Int. Appl., WO 2017026526 A1 20170216 (2017)<br></p>Formula:C18H20O4Color and Shape:NeatMolecular weight:300.35Propiolic Acid Sodium Salt (90%)
CAS:Controlled Product<p>Applications A bactericidal and fungicidal.<br>References Schoppelrei, J., et al.: J. Phys. Chem., 100, 14343 (1996), Kolb, H., et al.: Drug Discovery Today, 8, 1128 (2003),<br></p>Formula:C3HNaO2Purity:90%Color and Shape:NeatMolecular weight:92.031-(4-Chloro-3-methoxyphenyl)-4,4-dimethylpentan-3-one
CAS:Controlled ProductFormula:C14H19ClO2Color and Shape:NeatMolecular weight:254.75(5E)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one
CAS:Controlled Product<p>Applications (5E)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).<br></p>Formula:C18H15BrOColor and Shape:NeatMolecular weight:327.22Antifungal agent 76
CAS:<p>Antifungal agent 76 has broad-spectrum antifungal activity with a MIC value of 0.25-16 μg/mL.Antifungal agent 76 may act by disrupting fungal cell membranes and can be used to study fungal infections.</p>Formula:C17H20O2Purity:97.34%Color and Shape:SoildMolecular weight:256.34Benzyl 2-hydroxy-6-methoxybenzoate
CAS:<p>Benzyl 2-hydroxy-6-methoxybenzoate exhibits potent antifungal activity, demonstrating an IC 50 of 25–26 μg/mL against fungal strains.</p>Formula:C15H14O4Color and Shape:SolidMolecular weight:258.273Amphotericin X1
CAS:<p>Amphotericin X1, Amphotericin B derivative, has potent antifungal effects against various fungi (MICs: 1-8 μg/mL).</p>Formula:C48H75NO17Purity:98%Color and Shape:SolidMolecular weight:938.118Dicloran
CAS:<p>Dicloran is an aromatic fungicide that delays spore germination and inhibits hyphal growth, effective against Botrytis, Monilinia, Rhizopus, Sclerotinia.</p>Formula:C6H4Cl2N2O2Purity:99.47%Color and Shape:Yellow Needles From Alcohol And Acetic Acid Water But Often Formulated As A Wettable Powder (Easily Dispersed In Water)Molecular weight:207.01Butenafine
CAS:<p>Butenafine hydrochloride, a squalene epoxidase inhibitor, disrupts ergosterol synthesis, increasing cell membrane permeability.</p>Formula:C23H27NPurity:98%Color and Shape:SolidMolecular weight:317.47Antifungal agent 20
CAS:<p>Antifungal agent 20 effectively combats various fungi, like Colletotrichum spp., Rhizoctonia, Phytophthora, Diplodia, and Fusarium.</p>Formula:C11H19N3SColor and Shape:SolidMolecular weight:225.35Tecnazene
CAS:<p>Tecnazene is a giant myofibrillar protein. It also presents in invertebrate striated muscle.</p>Formula:C6HCl4NO2Color and Shape:SolidMolecular weight:260.89Abafungin
CAS:<p>Abafungin is an antifungal agent and is used for treating fungal infections.</p>Formula:C21H22N4OSPurity:Min. 95%Color and Shape:PowderMolecular weight:378.49 g/molLanoconazole
CAS:<p>Anti-fungal; sterol demethylase inhibitor</p>Formula:C14H10ClN3S2Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:319.83 g/molLuliconazole
CAS:<p>Broad spectrum imidazole antifungal</p>Formula:C14H9Cl2N3S2Purity:Min. 95%Color and Shape:Off-White To Yellow SolidMolecular weight:352.9615Bitertanol
CAS:<p>Bitertanol (KWG 0599) is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis.</p>Formula:C20H23N3O2Purity:99.88%Color and Shape:Clear Browm Clear LiquidMolecular weight:337.42(+)-Xylariamide A
CAS:<p>(+)-Xylariamide A is a probe used for mycobacterial and fungal carbonic anhydrase.</p>Formula:C14H14ClNO6Color and Shape:SolidMolecular weight:327.72Pyrifenox
CAS:<p>Pyrifenox is a pesticide and azole inhibitor.</p>Formula:C14H12Cl2N2OColor and Shape:SolidMolecular weight:295.16Enoxastrobin
CAS:<p>Enoxastrobin is a reagent biochemical.</p>Formula:C22H22ClNO4Purity:98%Color and Shape:SolidMolecular weight:399.87Prothioconazole
CAS:<p>Prothioconazole (Proline 480 SC Fungicide) is a chiral triazole fungicide in plant pathogen control.</p>Formula:C14H15Cl2N3OSPurity:99.77%Color and Shape:Un3077 9/Pg 3Molecular weight:344.26Flusilazole
CAS:<p>Flusilazole (DPX6573) is an organosilicon fungicide with broad spectrum antifungal effects.</p>Formula:C16H15F2N3SiPurity:99.56% - 99.64%Color and Shape:White SolidMolecular weight:315.39Demethoxyencecalin
CAS:<p>Demethoxyencecalin is extracted from Helianthus annuus with antifungal activities.</p>Formula:C13H14O2Purity:98.77%Color and Shape:Colorless Transparent Liquid Or White SolidMolecular weight:202.25Triforine
CAS:<p>Triforine is an agent of biochemical.</p>Formula:C10H14Cl6N4O2Purity:98%Color and Shape:SolidMolecular weight:434.96Butoconazole
CAS:<p>Butoconazole (1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole) is an imidazole antifungal agent</p>Formula:C19H17Cl3N2SPurity:99.33% - 99.65%Color and Shape:SolidMolecular weight:411.78(5-Methyl-3-trifluoromethylpyrazol-1-yl)acetic Acid
CAS:Controlled Product<p>Applications [5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid (cas# 345637-71-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C7H7N2O2F3Color and Shape:NeatMolecular weight:208.141,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole
Controlled Product<p>Applications 1,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole is derived from 5-([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazole (B397925), which is a structural isomer of Bifonazole (B383400) that is an anti-fungal agent used in the treatment of skin diseases. Bifonazole causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Formula:C41H32N2Color and Shape:NeatMolecular weight:552.715,6-Dehydromethysticin
CAS:Controlled Product<p>Applications 5,6-Dehydromethysticin is a proposed intermediate in the synthesis of 3-Hydroxyhispidin (H943133), a derivative of Hispidin. Hispidin (H436450) is a naturally occuring precursor to fungal luciferin responsible for luminosity in mushrooms.<br>References Lee, Y. et al.: Biol. Pharm. Bull., 31, 10 (1968); Purtov, K. et al.: Angew. Chem. Int. Ed., 54, 8124 (2014);<br></p>Formula:C15H12O5Color and Shape:NeatMolecular weight:272.253Ethyl 1-methyl-4-nitroimidazole-2-carboxylate
CAS:Controlled Product<p>Applications Ethyl 1-methyl-4-nitroimidazole-2-carboxylate<br></p>Formula:C7H9N3O4Color and Shape:NeatMolecular weight:199.16Benzyl Triflusulfuron
Controlled ProductFormula:C23H23F3N6O6SColor and Shape:NeatMolecular weight:568.525Dictamnine
CAS:Controlled Product<p>Applications Dictamnine is an herbal extract from the root of Dictamnus dasycarpus, and exhibits anti-microbial activity against bacteria and fungi. Phytotoxic agent.<br>References Guo, N. et al.: Yeast., 25, 631 (2008); Schempp, C. et al.: Planta. Med., 72, 941 (2006);<br></p>Formula:C12H9NO2Color and Shape:NeatMolecular weight:199.212-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-2-oxoacetic Acid Methyl Ester
CAS:Controlled Product<p>Applications 2-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-2-oxoacetic Acid Methyl Ester is an intermediate in the synthesis of (Z)-Azoxystrobin (A965155), a fungicide that inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1<br>References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),<br></p>Formula:C20H13N3O5Color and Shape:NeatMolecular weight:375.33Methyl DL-Mandelate
CAS:Controlled Product<p>Applications Methyl DL-Mandelate is a substrate for lipase B from Candida antarctica.<br>References Santos, J.C.S., et. al.: Enzyme Microb. Tech., 77, 1 (2015)<br></p>Formula:C9H10O3Color and Shape:NeatMolecular weight:166.17Cupric Nonylphenolsulfonate
CAS:Controlled ProductFormula:C30H46CuO8S2Color and Shape:NeatMolecular weight:662.3571-Methoxy-1-oxopropan-2-yl N-(2,6-Dimethylphenyl)-N-(2-methoxyacetyl)alaninate
Controlled Product<p>Applications 1-Methoxy-1-oxopropan-2-yl N-(2,6-Dimethylphenyl)-N-(2-methoxyacetyl)alaninate is a useful intermediate for organic synthesis processes. Potentially useful as a phytofungicide.<br>References Fr. Demande (1980), FR 2455574 A1<br></p>Formula:C18H25NO6Color and Shape:NeatMolecular weight:351.394(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS:Controlled ProductFormula:C13H15F2N3O4SColor and Shape:NeatMolecular weight:347.34Curvulin
CAS:Controlled Product<p>Applications Curvulin is a phototoxin that inhibits microtuble assembly.<br></p>Formula:C12H14O5Color and Shape:Off-WhiteMolecular weight:238.24p-(Allyloxy)benzyl Alcohol
CAS:Controlled Product<p>Applications p-(Allyloxy)benzyl Alcohol is an intermediate in the synthesis of 2-amino-nicotinic acid benzyl ester derivatives as agrochemical fungicides.<br>References Jpn. Kokai Tokkyo Koho (2015), JP 2015089883 A 20150511.<br></p>Formula:C10H12O2Color and Shape:NeatMolecular weight:164.23-Methylbenzenesulfonic Acid Monohydrate
CAS:Controlled ProductFormula:C7H8O3S·H2OColor and Shape:Light BrownMolecular weight:172.20 + (18.02)Benzyl 2-(Chlorosulfonyl)-3-methylbenzoate
CAS:Controlled ProductFormula:C15H13ClO4SColor and Shape:NeatMolecular weight:324.779Benzotriazol-1-ylacetic Acid
CAS:Controlled Product<p>Applications Benzotriazol-1-ylacetic Acid is used as a reagent in the synthesis of benzotriazole imidazoline compounds which are used as metal corrosion inhibitors. Benzotriazol-1-ylacetic Acid is also a reagent in the synthesis of N-(benzo[1,2,3]triazol-1-yl)-N-((benzyl)acetamido)phenyl carboxamides which are used as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors.<br>References Turlington, M., et al.: Bioorg, Med. Chem. Lett., 23, 6172 (2013); Chen, Y., et al.: Faming Zhuanli Shenqing. CN 103664902 A 20140326. Mar 26, 2014<br></p>Formula:C8H7N3O2Color and Shape:NeatMolecular weight:177.161-[(4R,5R)-N2-(10,12-Dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0
CAS:Controlled Product<p>Applications 1-[(4R,5R)-N2-(10,12-Dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall.<br>References Leonard, W. R., et al.: J. Org. Chem., 72, 2335 (2007);<br></p>Formula:C56H84N8O16SColor and Shape:Off-WhiteMolecular weight:1157.38N-Chloro-2,2,6,6-tetramethyl-4-piperidyl Methacrylate
CAS:Controlled Product<p>Applications A new N-halamine monomer was synthesized and used to prepare water-based polymeric N-halamines by emulsion polymn. Also, the compound was tested for antibacterial activity against Candida albicans, Staphylococcus aureus, and Escherichia coli.<br>References Kohl, H., et al.: J. Pharm. Sci., 69, 1292 (1980), Greenberger, P., et al.: Clin. Allergy Immunol., 16, 449 (2002), Gant, V., et al.: J. Antimicrob. Chemother., 60, 294 (2007), Pestka, J., et al.: Toxicol. Sci., 104, 4 (2008),<br></p>Formula:C13H22ClNO2Color and Shape:NeatMolecular weight:259.77(p-Nitrobenzylidene)malonic Acid Diethyl Ester
CAS:Controlled Product<p>Applications (p-Nitrobenzylidene)malonic Acid Diethyl Ester is an potential intermediate in the preparation of fungicides that are derived from modification of Diethyl-2-benzylidenemalonate, and is potentially used for agricultural purposes.<br>References Sidhu, A., et al.: Pesticide. Res. J., 21, 38 (2009);<br></p>Formula:C14H15NO6Color and Shape:NeatMolecular weight:293.27N,N-Bis(4-methoxybenzyl)amine
CAS:Controlled Product<p>Applications N,N-Bis(4-methoxybenzyl)amine acts as a reagent for the synthesis and biological evaluation of pentanedioc acid derivatives as farnesyltransferase inhibitors. Also used in the preparation of (heteroarylamino)triazolamines as antiviral agents useful in the treatment of HCV infection.<br>References Yang, L., et al.: MedChemComm, 6, 671 (2015); Chen, Z., et al.: PCT Int. Appl. (2014), WO 2014135483 A1 20140912<br></p>Formula:C16H19NO2Color and Shape:White To Off-WhiteMolecular weight:257.33
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