Antimicrobials

<p>Cefsulodin Sodium Salt Hydrate is an antibiotic compound, which is derived from synthetic chemical processes, specifically designed as a third-generation cephalosporin. It exhibits a mode of action by inhibiting bacterial cell wall synthesis, effectively targeting certain Gram-negative bacteria, particularly Pseudomonas aeruginosa, through the binding of penicillin-binding proteins. This binding disrupts the transpeptidation process essential for peptidoglycan cross-linking, compromising bacterial cell wall integrity and leading to cell lysis.</p>

<p>41-Oxo-rapamycin is a synthetic derivative of rapamycin, which is a macrocyclic lactone. It is derived from Streptomyces hygroscopicus, a gram-positive bacterium known for producing various bioactive compounds. The mode of action of 41-Oxo-rapamycin involves binding to the FK506-binding protein (FKBP12), forming a complex that subsequently inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition results in the suppression of T-cell proliferation and modulation of immune responses.</p>

<p>Aureothin is a bioactive compound, classified as a polyketide antibiotic, which is derived from the culture of the bacterium Streptomyces thioluteus. This compound operates primarily through the inhibition of protein synthesis by interfering with the aminoacylation of tRNA with specific amino acids. Its mode of action disrupts cellular protein synthesis, which is essential for cell growth and function, leading to its potent antibacterial and antifungal activities.</p>

<p>Pentabromopseudilin is a brominated natural product, which is isolated from marine bacteria, specifically the genus *Pseudomonas*. It operates by inhibiting the enoyl-acyl carrier protein reductase enzyme, interrupting fatty acid biosynthesis essential for bacterial and fungal cell membrane construction. As a halogenated phenol derivative, its unique mechanism of action makes it an interesting candidate for antimicrobial research.</p>

<p>Neomycin B is an aminoglycoside antibiotic, which is derived from the bacterium *Streptomyces fradiae*. It exerts its antibacterial effects by binding to the 30S subunit of bacterial ribosomes, leading to the inhibition of protein synthesis. This binding disrupts the translation process, thereby preventing the growth and proliferation of bacteria. Neomycin B is effective against a wide range of Gram-negative and some Gram-positive bacteria, making it a valuable tool in both medical and research settings.</p>

<p>GSK 3532795 is an investigational antiretroviral compound, which is a synthetic small molecule designed to inhibit HIV-1 capsid function. The source of this compound is GlaxoSmithKline, a pharmaceutical company actively engaged in the development of novel therapeutic agents. GSK 3532795 functions by disrupting the HIV-1 capsid, an essential protein shell that encases the viral RNA and associated enzymes. By targeting this structure, the compound interferes with numerous stages of the viral replication cycle, including disassembly, nuclear import, and encapsidation—thereby effectively inhibiting viral replication.</p>

<p>(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-((7-fluoro-1-hydroxy-1,3-dihydrobenzo[C][1,2]-oxaborol-6-yl)oxy)acetate is a novel antifungal compound derived from boron chemistry, representing a new class of therapeutic agents in the field of antifungal treatments. The compound primarily originates from the synthesis and refinement of boron-based molecular scaffolds, yielding a structure capable of disrupting fungal growth through a unique mode of action. It functions by inhibiting the fungal enzyme leucyl-tRNA synthetase, which is crucial in protein synthesis and thus vital for fungal cell survival and proliferation. By targeting this specific enzyme, the compound effectively halts the production of essential proteins, leading to the cessation of fungal growth and eventual cell death. The primary application of this compound is in the treatment of a range of fungal infections, particularly those that are resistant to conventional antifungal drugs, offering a potent alternative in clinical settings. The application of this compound spans both topical and systemic treatments, addressing a critical need for more effective antifungal therapies.</p>

<p>1,3,5-Triazine-2,4-diamine is a selective herbicide, which is synthesized from chemical feedstocks via a process involving triazine ring formation and chlorination. This compound operates by inhibiting photosynthesis in susceptible plants, specifically targeting the photosystem II complex. When absorbed through the roots and leaves, it disrupts the electron transport chain, leading to chlorophyll loss and subsequent plant death.</p>

<p>Panipenem is a carbapenem antibiotic, which is a type of beta-lactam antibiotic derived from thienamycin. It functions by inhibiting penicillin-binding proteins (PBPs), which are essential for bacterial cell wall synthesis. This inhibition disrupts the cell wall construction, leading to cell lysis and death, thereby demonstrating strong bactericidal activity.</p>

<p>Elsulfavirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI), which is derived from advanced medicinal chemistry efforts targeting specific interactions with the HIV-1 reverse transcriptase enzyme. The mode of action of Elsulfavirine involves the inhibition of reverse transcriptase activity by binding to an allosteric site on the enzyme, thereby preventing the transcription of viral RNA into DNA, a critical step in the HIV replication process.</p>

<p>Beauvericin is a cyclic peptide that is isolated from the fungus Fusarium. It has been shown to have antimicrobial activity against bacteria, as well as a variety of other biological properties. Beauvericin has been shown to inhibit mitochondrial membrane potential and induce toxicity in some animal models. Beauvericin also inhibits protein synthesis and causes cell death by inhibiting DNA polymerase activity. This compound is active against cancer cells, including HL-60 cells, which are derived from human lymphocytes and are used as a model for leukemia. Beauvericin can be extracted from an ETOA extract of the fungus Fusarium oxysporum; this extract has shown anti-cancer effects in vitro assays.</p>

<p>Fenaminostrobin is a broad-spectrum fungicide, which is synthesized chemically. It operates primarily through inhibition of mitochondrial respiration in fungal cells, targeting the bc1 complex, which disrupts ATP production and leads to the inhibition of spore germination and fungal growth. This mode of action makes Fenaminostrobin effective against a wide range of pathogenic fungi that affect various crops.</p>

<p>Zelkovamycin is a novel antibacterial compound isolated from endophytic microorganisms, specifically Streptomyces sp. Endophytes are bacteria or fungi that reside within plant tissues, forming symbiotic relationships and often producing bioactive metabolites. The mode of action of Zelkovamycin involves the inhibition of bacterial cell wall synthesis, interfering with the biosynthesis pathways essential for maintaining the structural integrity and function of bacterial cell walls, particularly in Gram-positive strains.</p>

<p>(3R,4R)-A2-32-01 is an innovative insecticide, which is a synthetic product derived from intensive research in entomology and organic chemistry. It operates by targeting the neurological pathways of specific insect pests, leading to rapid cessation of feeding and, ultimately, death. This mode of action is highly selective, affecting only targeted pest species while minimizing impact on non-target organisms such as beneficial pollinators.</p>

<p>Picoxystrobin metabolite M8 is a chemical metabolite, which is a derivative specifically originating from the degradation of the fungicide Picoxystrobin. It is generated through the metabolic pathways that occur after the application of Picoxystrobin on crops. As a strobilurin derivative, its mode of action is primarily related to its ability to disrupt mitochondrial respiration in fungi by inhibiting the electron transport chain at the cytochrome bc1 complex. This interruption leads to energy depletion and subsequent cell death in pathogenic fungi.</p>

<p>PNU 142300 is a non-peptidyl anticoagulant, which is a synthetically derived small molecule. This compound is sourced from advanced chemical synthesis techniques that focus on mimicking biological activity through non-biological materials. PNU 142300 acts by specifically inhibiting factor Xa, a crucial enzyme in the coagulation cascade responsible for the conversion of prothrombin to thrombin. By targeting this enzyme, it effectively prevents the formation of blood clots, thereby exhibiting potent anticoagulant properties.</p>

<p>Marbofloxacin hydrochloride is a synthetic, broad-spectrum antibacterial agent. It is derived from the fluoroquinolone class, which is known for its potent activity against a variety of bacterial pathogens. The mode of action of marbofloxacin hydrochloride involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication, transcription, and repair processes. This inhibition disrupts bacterial cell division and ultimately leads to cell death.</p>

<p>Heronapyrrole B is a naturally occurring marine-derived antibiotic, which is isolated from a species of marine-derived Streptomyces. This compound is a member of the pyrrole-2-aminoimidazole family, which is characterized by its unique structural framework that contributes to its biological activity. The mode of action of Heronapyrrole B involves disrupting bacterial cell membranes, thereby hindering cell growth and survival. This mechanism is particularly effective against a range of Gram-positive bacteria.</p>

<p>Nortadalafil-N-(2-hydroxy)propyl is a chemotherapeutic agent, which is synthesized through the chemical modification of tadalafil. It is characterized as a small-molecule inhibitor, derived from the structural alteration of the well-known phosphodiesterase type 5 (PDE5) inhibitor. The mechanism of action involves the attenuation of PDE5 activity, leading to increased levels of cyclic guanosine monophosphate (cGMP) within targeted cellular pathways. This elevation in cGMP concentration results in vasodilation and increased blood flow, primarily investigated within the context of vascular and erectile tissue.</p>

<p>Solithromycin is a novel macrolide antibiotic, which is derived from the compound ketolide. It functions by binding to the bacterial 50S ribosomal subunit, effectively inhibiting protein synthesis. This mechanism of action enables Solithromycin to exert its effects against a wide range of bacterial pathogens, including strains resistant to traditional macrolides. The unique binding capability to multiple sites on the ribosome enhances its potency and reduces the likelihood of resistance development.</p>

<p>Decoyinine is an antibiotic compound, which is derived from the bacterium *Streptomyces hygroscopicus*. Its mode of action involves the inhibition of guanine nucleotide synthesis. By targeting the biosynthesis pathway of nucleotides, Decoyinine effectively impedes the growth and proliferation of bacterial cells.</p>

<p>Sarecycline Hydrochloride is a narrow-spectrum tetracycline antibiotic with action on bacterial protein synthesis inhibition and is used for treating moderate to severe acne vulgaris.</p>

<p>2,6-Bis(2-ethylhexyl)-7a-methylhexahydro-1H-imidazo[1,5-c]imidazole, known as hexedine, is a synthetic compound, which is primarily utilized in industrial applications. It is derived from a chemical synthesis process involving imidazo-imidazole structures, allowing for specific modifications to yield its characteristic properties. Hexedine operates through a mechanism that enhances surface adhesion and stability when applied to various substrates. The compound’s molecular architecture enables it to form a durable, resistant layer, thereby improving the surface’s integrity and lifespan.</p>

<p>Deacetoxycephalothin is a cephalosporin antibiotic, which is derived from the fungus Acremonium. It functions by inhibiting bacterial cell wall synthesis. This bactericidal activity is primarily focused on gram-positive bacteria, where it interferes with the final transpeptidation step of peptidoglycan synthesis, an essential component of the bacterial cell wall structure. By doing so, deacetoxycephalothin compromises cell wall integrity, leading to the lysis and death of bacterial cells.</p>

<p>Sofosbuvir is an antiviral agent that is used for the treatment of hepatitis C infections and is used in combination with other antiviral agents. This drug is an inhibitor of viral RNA polymerase called non-structural protein 5B (NS5B). As a result, it inhibits viral RNA replication.</p>

<p>Stavudine sodium is an antiretroviral medication, which is a synthetic nucleoside analogue. It is primarily sourced from chemical synthesis processes, enabling precise control over its molecular structure to ensure efficacy in its intended application. The mode of action for stavudine sodium involves its incorporation into viral DNA through reverse transcription. Once integrated, it acts as a chain terminator, inhibiting the elongation of the viral DNA and thus effectively halting the replication of the human immunodeficiency virus type 1 (HIV-1).</p>

<p>Pristinamycin IA is a streptogramin antibiotic, which is a natural product derived from the bacterium *Streptomyces pristinaespiralis*. It operates by inhibiting bacterial protein synthesis through the disruption of ribosomal function, specifically targeting the 50S ribosomal subunit. This mode of action is effective in halting bacterial growth, making it particularly significant in combating resistant strains.</p>

<p>Paritaprevir is an antiviral medication, which is derived from chemical synthesis with its action targeting the hepatitis C virus (HCV). It operates primarily as a protease inhibitor, specifically targeting the NS3/4A protease, an essential enzyme for HCV replication. By inhibiting this protease, Paritaprevir effectively disrupts the viral life cycle, preventing the virus from maturing and proliferating within the host cells.</p>

<p>Finafloxacin is a fluoroquinolone antibacterial agent, which is a synthetic compound derived from the quinolone family. It functions through the inhibition of bacterial DNA gyrase and topoisomerase IV, crucial enzymes in the replication, transcription, and repair of bacterial DNA. This mechanism leads to the prevention of bacterial cell division and ultimately results in cell death.</p>

<p>Please enquire for more information about Isoflucypram including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-((3-(4-(1,1-Dioxidothiomorpholin-4-yl)-3,5-difluorophenyl)-2-oxo-1,3-oxazolidin-5-yl)methyl)acetamide is a synthetic compound, often considered within the realm of small-molecule pharmacology. This compound is derived through complex organic synthesis, involving the incorporation of dioxidothiomorpholine and oxazolidinone rings, as well as fluorination, which are critical for its biochemical properties.</p>

<p>Ribocil B is an analog of riboflavin, functioning as a synthetic antibiotic. It is derived from chemical synthesis, designed to mimic the structure of natural riboflavin analogs which are crucial for bacterial growth. Ribocil B acts by specifically inhibiting riboswitches, a type of non-coding RNA that regulates gene expression in response to small molecules. This inhibition disrupts RNA synthesis in bacteria by targeting the flavin mononucleotide (FMN) riboswitch.</p>

<p>Clofoctol is an antibacterial agent, which is derived from synthetic origins, specifically designed for therapeutic applications in bacterial infections. Its mode of action involves inhibiting bacterial protein synthesis, thereby preventing the growth and proliferation of harmful bacteria. This compound is particularly effective against Gram-positive bacteria.</p>

<p>Neoaureothin is a natural antibiotic product, which is derived from marine actinomycetes with a complex polyketide structure. Its mode of action involves the inhibition of bacterial protein synthesis by binding selectively to the ribosomal subunits, thereby obstructing the translation process in susceptible microbial strains. The specificity of its action allows it to target a broad spectrum of Gram-positive bacteria while presenting a lower risk of resistance development compared to traditional antibiotics.</p>

<p>Dimidazon is a synthetic herbicide, which is derived from chemical synthesis processes involving aromatic and heterocyclic compounds. It possesses a mode of action that primarily inhibits specific enzymatic pathways required for plant growth, targeting essential biosynthesis mechanisms within the plant's cellular structure. This disruption leads to the cessation of vital processes, eventually causing plant death.</p>

<p>Pentosan polysulfate is a semi-synthetic polysaccharide, which is derived from xylan, sourced from beechwood hemicellulose. It functions as a heparin-like compound with anticoagulant and fibrinolytic properties. Its sulfated polysaccharide form allows it to adhere to the urothelium of the bladder, forming a protective layer that can prevent irritating solutes in urine from reaching bladder cells. Through this mechanism, it mitigates the pain and discomfort associated with interstitial cystitis (IC), a chronic condition characterized by bladder pain and urinary urgency.</p>

<p>Polymyxin B nonapeptide hydrochloride is a potent antibiotic compound derived from the bacterium *Bacillus polymyxa*. As a cationic polypeptide, it exhibits its antibacterial activity by interacting with the lipopolysaccharides and phospholipids in the bacterial cell membrane, leading to increased permeability and ultimately causing cell lysis. The compound is specifically effective against a broad range of Gram-negative bacteria, making it crucial in studying antibiotic resistance mechanisms.</p>

<p>Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic, which is a synthetic derivative of the broad-spectrum quinolone class. Its origin can be traced to laboratory chemical synthesis, tailored specifically to target bacterial infections in ocular applications. The mode of action of besifloxacin involves the inhibition of bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes play crucial roles in bacterial DNA replication, transcription, repair, and recombination. By disrupting these processes, besifloxacin effectively impedes bacterial cell division, leading to the death of the bacterial cells.</p>

<p>Cefluprenam is a cephalosporin antibiotic, which is a synthetic derivative of the fungus Cephalosporium. It functions by inhibiting bacterial cell wall synthesis, effectively disrupting the peptidoglycan cross-linking process essential for bacterial structural integrity. This inhibition leads to cell lysis and ultimately bacterial death.</p>

<p>Cefoxitin EP impurity B is a chemical reference standard, which is derived from the synthesis and purification processes involved in producing Cefoxitin. As an impurity standard, its primary role is to serve as a benchmark for quality control in pharmaceutical formulations. The mode of action of Cefoxitin EP impurity B involves the structural analysis and quantification of impurity levels, ensuring that the primary pharmaceutical products meet necessary safety and efficacy criteria.</p>

<p>Spiro-oxanthromicin A is a novel antibiotic compound, which is derived from a rare species of actinomycete bacteria. The unique structure of Spiro-oxanthromicin A integrates spiroketal and oxanthrone moieties, facilitating its distinctive antimicrobial properties. It operates by selectively binding to bacterial ribosomal subunits, inhibiting protein synthesis and effectively curbing pathogenic proliferation.</p>

<p>Butirosin disulfate is an aminoglycoside antibiotic, which is derived from a strain of *Bacillus circulans*. Its primary mode of action involves binding to the 30S subunit of the bacterial ribosome, leading to the inhibition of protein synthesis. This interaction results in the misreading of mRNA, ultimately causing bactericidal effects.</p>

<p>Nigericin transports cations across the membrane of the cell and it is used to study anion transport. It can be used as a buffer to control pH value inside of the cell.</p>

<p>(2S)-2-[N-(Furan-2-carbonyl)-2,6-dimethylanilino]propanoic acid is a synthetic compound classified as a potentially bioactive molecule. It is derived through a series of organic synthesis steps that involve the coupling of furan-2-carbonyl chloride with 2,6-dimethylaniline, followed by modification with a chiral propanoic acid moiety.</p>

<p>Sulfamethazine Sodium Salt is a synthetic sulfonamide antibacterial agent derived from sulfanilamide compounds, characterized by its broad-spectrum efficacy against various bacterial pathogens. It operates by interfering with bacterial folic acid synthesis, specifically inhibiting the enzyme dihydropteroate synthase. This action results in the incapacitation of bacterial growth and replication, as folic acid is essential for nucleic acid formation and cell division.</p>

<p>Quinocarcin is an antitumor antibiotic, which is a potent chemical compound derived from the bacterium Streptomyces. This compound exhibits its mode of action through interaction with DNA, where it induces DNA cross-linking and inhibits DNA replication, ultimately leading to cell death. The mechanism makes it particularly effective as a cytotoxic agent against rapidly dividing cancer cells.</p>

<p>InteriotherinA is a bioactive compound, which is derived from specific strains of bacteria. It operates through a sophisticated mode of action that involves modulating the activity of nerve cells by binding to particular receptors on their membranes. This interaction can alter ion channel function, thereby influencing the electrochemical signaling within these cells.</p>

<p>Cefquinome is a broad-spectrum antibiotic, which is a fourth-generation cephalosporin. It is derived from the β-lactam class of antibiotics and is specifically designed for veterinary applications. Its mode of action involves the inhibition of bacterial cell wall synthesis, leading to cell lysis and death. This action is facilitated through the binding of cefquinome to penicillin-binding proteins, which undermines the structural integrity of bacterial cell walls, proving effective against both Gram-positive and Gram-negative bacteria.</p>

<p>ACX-362E is a novel antibacterial agent, which is a synthetic compound derived from small-molecule chemical libraries with selective action on bacterial pathogens. The mode of action of ACX-362E involves the inhibition of bacterial cell wall synthesis, specifically targeting essential enzymes involved in the peptidoglycan biosynthesis pathway. This interference disrupts cell wall integrity, leading to bacterial lysis and cell death.</p>

<p>Desmethyl doxorubicin oxalate is an anthracycline-type chemotherapeutic agent, which is derived from the naturally occurring antibiotic doxorubicin. This compound comprises a desmethylated form of doxorubicin combined with oxalate. Its mode of action involves intercalating DNA strands and inhibiting topoisomerase II, thereby disrupting DNA replication and transcription. This interference leads to the inhibition of cancer cell proliferation and induces apoptosis.</p>

<p>Nicotinamide is an amide form of vitamin B3, which is a water-soluble vitamin derived from dietary sources such as meat, fish, and yeast. In cellular biology, it functions as a precursor to nicotinamide adenine dinucleotide (NAD+), a critical coenzyme in redox reactions and energy production within the cells. Nicotinamide facilitates the transfer of electrons in metabolic processes, contributing to ATP production and cellular respiration. Moreover, it plays a pivotal role in DNA repair and cellular signaling through the regulation of sirtuins and poly(ADP-ribose) polymerases (PARPs).</p>

<p>N'-Desmethyl azithromycin is a semi-synthetic derivative antibiotic, which is derived from the chemical modification of azithromycin, a macrolide antibiotic sourced originally from the bacterium *Streptomyces erythreus*. It functions primarily by inhibiting bacterial protein synthesis, binding specifically to the 50S ribosomal subunit, which results in the prevention of transpeptidation and translocation processes during translation. This action effectively halts bacterial growth, rendering it bacteriostatic.</p>

<p>Sulfasymazine is a synthetic antibacterial agent, which is derived from sulfonamide compounds. These compounds originate from chemical synthesis processes involving the introduction of sulfonamide groups to aromatic amines, creating potent inhibitors of bacterial growth. Sulfasymazine functions by interfering with the synthesis of folic acid within bacterial cells. It inhibits the enzyme dihydropteroate synthase, which is crucial for the production of dihydrofolate, a precursor of folic acid. This disruption hampers nucleic acid synthesis, impeding bacterial proliferation.</p>

<p>Ceftaroline fosamil is an advanced antibiotic, which is a cephalosporin derived from synthetic sources with a broad spectrum of activity. It is a prodrug that, once metabolized, becomes active in the body, binding to penicillin-binding proteins (PBPs) of bacteria. This binding inhibits the proteins responsible for cell wall synthesis, leading to bacterial cell lysis and death.</p>

<p>Baumycin C1 is an anthracycline-type antibiotic, which is derived from the bacterium *Streptomyces coeruleorubidus*. The mode of action of Baumycin C1 involves intercalating into DNA strands, thereby disrupting the process of DNA synthesis and replication. This intercalation results in the inhibition of topoisomerase II, an enzyme crucial for DNA unwinding, leading to the generation of double-strand breaks and subsequent interruption of cellular proliferation.</p>

<p>1-Chloro-2,2-bis(4'-chlorophenyl)ethane is an organochlorine pesticide known for its agricultural applications. It is a synthetic product derived from chlorinated hydrocarbons. It functions primarily through its mode of action as an insecticide by interfering with the nervous system of insects. It disrupts normal nerve function by causing prolonged opening of sodium channels in nerve cells, leading to hyperexcitation and eventual paralysis of the target pests.</p>

<p>Balapiravir is an antiviral agent, which is a synthetic derivative based on natural compounds, specifically designed to inhibit the replication of various viral pathogens. The source of Balapiravir integrates bio-based elements with modifications to enhance its therapeutic efficacy.</p>

<p>Chlorsulfuron-5-hydroxy is a herbicide derivative, specifically an active metabolite of chlorsulfuron, which is a sulfonylurea herbicide. This compound is derived from synthetic chemistry processes that focus on altering the molecular structure of chlorsulfuron to enhance its properties or study its breakdown. The mode of action of Chlorsulfuron-5-hydroxy involves the inhibition of the enzyme acetolactate synthase (ALS), which plays a crucial role in the biosynthesis of branched-chain amino acids in plants such as valine, leucine, and isoleucine. This inhibition disrupts protein synthesis, leading to halted cell division and plant growth.</p>

<p>Please enquire for more information about Kanzonol C including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PK150 is a soil amendment product, which is derived from natural mineral sources with a specific focus on enhancing plant growth through optimized nutrient uptake efficiency. This product works by modifying the soil's physical and chemical properties, thereby improving the availability and mobility of essential nutrients like phosphorus (P) and potassium (K), which are crucial for the development and yield of plants.</p>

<p>2'-O-Acetylspiramycin I is a semi-synthetic derivative of spiramycin, which is a macrolide antibiotic originally sourced from the bacterium *Streptomyces ambofaciens*. The modification involves the acetylation at the 2'-hydroxyl group of spiramycin, enhancing certain pharmacokinetic properties.</p>

<p>Please enquire for more information about Fomidacillin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sultasin is a combination antibiotic product, which is derived from the synthesis of sulbactam, a β-lactamase inhibitor, and ampicillin, a β-lactam antibiotic. The mode of action of Sultasin involves the inhibition of bacterial cell wall synthesis. Ampicillin works by attaching to penicillin-binding proteins (PBPs) inside the bacterial cell wall, disrupting the final transpeptidation step of peptidoglycan synthesis, which leads to cell lysis. Sulbactam enhances the efficacy of ampicillin by inhibiting β-lactamase enzymes produced by resistant bacterial strains, thereby preventing the degradation of the antibiotic.</p>

<p>Mitomycin D is an antibiotic and chemotherapeutic agent known for its ability to inhibit DNA synthesis, making it a potent antitumor agent. It is derived from the bacterium *Streptomyces caespitosus*. Mitomycin D functions as a DNA crosslinking agent by alkylating the DNA strands, which interferes with DNA replication and transcription. This mechanism leads to the cessation of cellular division and ultimately induces apoptosis in rapidly dividing cells.</p>

<p>Please enquire for more information about BPH715 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Aclacinomycin HCl is a cytotoxic antibiotic that inhibits the growth of tumor cells. It has been shown to induce apoptosis in human leukemia cells by altering the transmembrane potential and inhibiting cell proliferation. Aclacinomycin HCl also induces DNA damage response, which leads to caspase activities and cell death. This drug is highly selective for tumor cells, with no effect on normal cells. It has been shown to be effective against primary liver cancer in animal models, as well as developmental disorders such as autism spectrum disorder (ASD).</p>

<p>Sarecycline is a tetracycline-class antibiotic, which is derived from naturally occurring tetracycline antibiotics. Its mode of action involves inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to nascent peptide chains. This specific mechanism disrupts bacterial growth, making Sarecycline effective against certain strains of bacteria implicated in dermatological conditions.</p>

<p>Violacein is a model system for studying the effects of hydroxyl groups on cell lysis. It is a fatty acid that contains nitrogen atoms and has antimicrobial properties. Violacein has been shown to cause the loss of mitochondrial membrane potential in HL-60 cells, which may be due to its ability to act as a multidrug efflux pump inhibitor. Violacein also exhibits antimicrobial activity against several bacterial strains, including MRSA and methicillin-sensitive Staphylococcus aureus (MSSA). In addition, violacein has been shown to induce cell lysis in vitro via the degradation of proteins and lipids in the cytoplasm.</p>

<p>Gatifloxacin hydrate is a fluoroquinolone antibiotic, which is synthesized chemically. It exerts its bactericidal effects primarily by inhibiting bacterial DNA gyrase and topoisomerase IV. These enzymes are crucial for bacterial DNA replication, transcription, and repair. By preventing these processes, gatifloxacin effectively halts bacterial cell division, ultimately leading to cell death.</p>

<p>CEF3 is a cephalosporin-based antibacterial agent, which is derived from the fermentation of Streptomyces species. This compound functions by inhibiting bacterial cell wall synthesis, specifically targeting the transpeptidase enzyme involved in the cross-linking of peptidoglycan layers. The disruption of this process results in weakened bacterial cell walls, leading to cell lysis and death, particularly affecting Gram-positive and some Gram-negative bacteria.</p>

<p>Tebufenozide-hydroxymethyl is an insect growth regulator, which is synthesized chemically to function as an agonist of the molting hormone, ecdysone, in target pest species. It operates by mimicking the effects of ecdysone, leading to premature and lethal molting in lepidopteran larvae. This disruption in the developmental cycle of the insects effectively suppresses their population by preventing them from reaching maturity and reproducing.</p>

<p>L-689502 is a synthetic compound that functions as a selective antagonist for neuropeptide Y1 receptors. It is derived from chemical synthesis processes specifically designed to target and modulate these receptors. As an antagonist, its primary mode of action involves binding to the neuropeptide Y1 receptors and inhibiting their activity, thereby blocking the effects of the naturally occurring ligand, neuropeptide Y (NPY).</p>

<p>Cycloxaprid is an insecticide, which is a chemical derived from natural compounds designed to manage pest populations. Its primary source is based on a modification of the neonicotinoids, a class of neuro-active insecticides modeled after nicotine. Cycloxaprid functions by acting on nicotinic acetylcholine receptors (nAChRs) within the insect’s nervous system. This mode of action involves binding to these receptors, leading to uncontrolled nerve firing and eventually, the insect’s death due to nervous system failure.</p>

<p>N-Acetyl glyphosate-13C2,15N is a stable isotope-labeled analog of the well-known herbicide glyphosate. This product is synthesized using isotopically enriched carbon and nitrogen sources. Its mode of action involves inhibiting the shikimate pathway by targeting the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), crucial for aromatic amino acid biosynthesis in plants. This pathway is not present in animals, making it a valuable target for selective herbicidal action.</p>

<p>Methyl N-[2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]carbamate is a selective insecticide, which is primarily pyrazole-based in nature. It is synthetically derived, allowing for precise structural control over its active components. The compound functions through a specific mode of action targeting the skeletal muscle function of insects by interfering with calcium ion channels. This disruption leads to impaired muscle contractions and eventual paralysis of the target pests.</p>

<p>Pikromycin is an antibiotic, which is derived from the bacterium *Streptomyces venezuelae*. It functions by specifically binding to the 50S ribosomal subunit, thereby inhibiting bacterial protein synthesis. This action effectively blocks peptide chain elongation, leading to the cessation of bacterial growth and proliferation. Pikromycin serves as an important model compound in antibiotic research, particularly in the study of macrolides and polyketides, due to its unique structure and biosynthetic pathway.</p>

<p>Cyclosporin L is an immunosuppressive agent, which is a cyclic polypeptide derived from the soil fungus Tolypocladium inflatum. It primarily functions by inhibiting the activity of calcineurin, a key phosphatase involved in the activation of T-cells. This inhibition prevents the transcription of interleukin-2 and other cytokines critical for T-cell proliferation.</p>

<p>4''-(p-Fluorobenzyl)tylosin A is a semi-synthetic derivative of tylosin, which is a macrolide antibiotic produced by fermentation of the bacterium *Streptomyces fradiae*. This compound demonstrates a modified structure by incorporating a p-Fluorobenzyl group at the 4'' position of tylosin, enhancing its pharmaceutical properties. The mode of action involves binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis and exerting its bacteriostatic effects against Gram-positive bacteria.</p>

<p>1H-Indene-2-carboxylic acid is an organic compound, which is primarily utilized in synthetic organic chemistry. This compound is a derivative of indene, a bicyclic hydrocarbon derived from the fusion of benzene and cyclopentene rings. It is most commonly sourced from petrochemical processes involving the polymerization or catalytic conversion of hydrocarbons.</p>

<p>Papyracillic acid is a bioactive compound, classified as a secondary metabolite, which is isolated from certain species of fungi. This compound originates from the natural metabolic processes of these microorganisms, often cultured on specific media to optimize production levels. Its mode of action involves disrupting essential bacterial cellular functions, primarily by inhibiting the synthesis of key structural components, leading to compromised integrity and function of bacterial cells.</p>

<p>Tromantadine hydrochloride is a synthetic antiviral compound, which is a derivative of adamantane. It originates from chemical synthesis, tailored specifically to target viral processes. Tromantadine hydrochloride primarily exerts its effects by inhibiting the penetration of virus particles into host cells and impeding the subsequent stages of viral replication. This mode of action effectively reduces the viral load and hinders the progression of the infection.</p>

<p>Ikarugamycin is a polycyclic nitrogenous antibiotic, which is derived from the fermentation of Streptomyces species, a genus of gram-positive bacteria. It acts primarily by inhibiting clathrin-mediated endocytosis, a cellular process involving the internalization of various macromolecules. This inhibition disrupts cellular uptake mechanisms, which has significant implications for its utility in biological research and therapeutic applications.</p>

<p>Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.</p>

<p>Azaconazole is a systemic fungicide, which is derived from synthetic chemical processes, specifically within the class of triazoles. This compound functions by interfering with the biosynthesis of ergosterol, a critical component of fungal cell membranes. By inhibiting the cytochrome P450 enzyme 14α-demethylase, azaconazole disrupts the production of ergosterol, thereby compromising membrane integrity and inhibiting fungal growth.</p>

<p>Aqabamycin D is a novel antibiotic compound, which is derived from marine bacteria, particularly from the genus Streptomyces collected from unique marine environments. This compound functions by interfering with bacterial cell wall synthesis, leading to the disruption of essential cellular processes. Aqabamycin D exhibits a broad spectrum of antibacterial activity, particularly against gram-positive bacteria, making it a valuable tool for tackling resistant bacterial strains.</p>

<p>Carbophenothion-methyl-sulfoxide is an organophosphate sulfoxide compound, which is synthesized as a sulfoxide derivative from other organophosphate precursors. It acts as an acetylcholinesterase inhibitor, disrupting the normal function of the enzyme acetylcholinesterase, which is critical for nerve signal transmission in insects. This disruption leads to an accumulation of acetylcholine and subsequent insect paralysis and death. Carbophenothion-methyl-sulfoxide is primarily used in agricultural settings to target a broad spectrum of insect pests that affect crops. Its application can significantly reduce pest populations, ensuring crop protection and yield preservation. Being a sulfoxide variant, it may possess distinctive physicochemical properties that confer specific environmental behavior and degradation pathways compared to its non-sulfoxide counterparts. Proper handling and application are essential to minimize potential ecological impacts, including non-target species effects and resistance development.</p>

<p>26-Oxofusidic acid is a derivative of fusidic acid, which is a potent antibacterial compound originally isolated from the fungus Fusidium coccineum. This compound exhibits a unique mode of action by inhibiting bacterial protein synthesis through interference with the elongation factor G (EF-G), a critical component in the translocation step of translation. By targeting this specific aspect of bacterial metabolism, 26-Oxofusidic acid effectively disrupts the growth of gram-positive bacteria, making it an invaluable tool in combating resistant bacterial strains.</p>

<p>Norvancomycin trifluoroacetate is an antibiotic compound, which is a glycopeptide derived from the bacterium Amycolatopsis orientalis. Its mode of action involves inhibiting bacterial cell wall synthesis. Specifically, Norvancomycin disrupts the cross-linking of peptidoglycan layers in the bacterial cell wall by binding to the D-alanyl-D-alanine terminus of cell wall precursors. This disruption weakens the bacterial cell wall, ultimately leading to cell lysis and death, thereby exerting a bactericidal effect.</p>

<p>Chlorhexidine acetate hydrate (1:2:X) is a chemical compound used as a disinfectant and antiseptic. It is derived from chlorhexidine, a well-known antimicrobial agent frequently used in both medical and laboratory settings. The compound functions by disrupting microbial cell membranes, resulting in leakage of cellular components and subsequent cell death. This action makes it particularly effective against a wide range of bacteria, fungi, and some viruses.</p>