Antimicrobials

Applications ​[5-​[(3aS,​4S,​6aR)​-​Hexahydro-​2-​oxo-​1H-​thieno[3,​4-​d]​imidazol-​4-​yl]​-​1-​oxopentyl]​-​3-​(2-​pyridinyldithio)​-L-alanine is an intermediate in the synthesis of Biotinyl Pyridinyldithio N-Hydroxysuccinimide Alanine Ester (B397300), which is an antimicrobial bisulfide prodrug.
References Ponpipom, et al.: J. Med. Chem., 24, 1388 (1981), Hausch, F., et al.: Bioconjug. Chem., 8, 885 (1997), Seelig, B., et al.: Chem. Biol., 6, 167 (1999),

Applications 2,7-Dibromonapthalene acts as a reagent for the expedient synthesis of aminopropoxy-functionalized bis(aryltriazoly) arylenes via click chemistry and their antimicrobial and hemolytic activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fu, T., et al.: ACS Med. Chem. Lett., 4, 841 (2013)

Applications 2,2'-Methylenebis(4-bromophenol) can be derived from bromophenols from the red alga Odonthalia corymbifera and display potential antimicrobial activity. It is used as an intermediate in the synthesis of Albuterol Dimer (A514515) which is an impurity of the drug Albuterol used to treat asthma.
References Oh, K., et al.: Bioorg. Med. Chem. Lett., 18, 104 (2008); Haddad, N., et al.: Tetrahedron Lett., 43, 1135 (2002);

Stability moisture sensitive
Applications 4,7-Difluoro-1,3-isobenzofurandione is used in the synthesis of phthalic compounds, phthalazines, and quinones with antimicrobial activity.
References Cardia, M. et al.: J. Hetero. Chem., 40, 1011 (2003); Krohn, K.. et al.: Sci. Synth., 28, 367 (2006); Vina, D. et al.: Tetrahedron, 65, 1574 (2009);

Ceftiofur is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating bacterial infections in veterinary medicine.

Kitasamycin is a macrolide antibiotic with a mode of action that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It is used for treating bacterial infections in veterinary medicine.

Gentamicin C2a is an aminoglycoside antibiotic, which is a complex of compounds derived from the fermentation of the bacterium *Micromonospora purpurea*. Its mode of action involves binding to the bacterial 30S ribosomal subunit, thereby inhibiting protein synthesis and resulting in the bactericidal effect on susceptible strains. The disruption of protein synthesis prevents the growth and replication of bacteria, effectively killing them.

Dibekacin sulfate is an aminoglycoside antibiotic with action on bacterial protein synthesis inhibition and is used for treating severe gram-negative bacterial infections.

ester of Monensin.  Monensin is a polyether antibiotic isolated from Streptomyces cinnamonensis.  It is widely used in ruminant animal feeds.

Applications 2,3-Dichloro-6-nitroaniline is used as a reagent in the synthesis of 3-alkyl-, 3-halomethyl- and 3-carboxyethylquinoxaline-2-ones which have potential antimicrobial activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Carta, A., et al.: Farmaco, 58, 1251 (2003)

Applications 4,7-Dichloro-2-phenyl-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of phthalic compounds, phthalazines, and quinones with antimicrobial activity.
References Marriott, G. J., et al.: J. Chem. Soc., 134 (1939); Katayama, H., et al.: Tetrahedron., 63, 6642 (2007);

Stability Hygroscopic
Applications Berberrubine Chloride is a novel alkaloid with novel nitric-oxide donating activity. Antitumor and an antimicrobial agent.
References Chen, J. et al.: Eur. J. Med. Chem., 132, 173 (2017); Jeyakkumar, P. et al.: Bioorg. Med. Chem. Lett., 27, 1737 (2017);

Applications Benzyltriphenylphosphonium Chloride was used as a reagent in the organic synthesis of several compounds including that of stabilised phosphonium ylides containing saturated oxygen heterocycles. Also used in the synthesis of novel substituted cis-stilbene derivatives which display antimicrobial activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Aitken, R., et al.: Org. Biomol. Chem., 14, 1794 (2016); Jain, D., et al.: World J. Pharm. Sci., 4, 1473 (2015);

Applications A 6-substituted 8-quinolinecarboxylic acid as antimicrobial and genotoxic agent.
References Weyer, R., et al.: Arzneim.-Forsch., 24, 269 (1974),

Applications 1,14-Tetradecanediol is a bioactive component of Hybanthus enneaspermus with anti-microbial activity against microbes.
References Anand, T., et al.: Int. J. Pharm. Pharm. Sci., 4, 646 (2012)

Applications (1R,2S,3R)-1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is an intermediate in the synthesis of 2-Quinoxalinecarboxylic Acid (Q765265), a residue of Carbadox (C175825) which is an antimicrobial drug.
References Harms, A.E., et al.: Org. Proc. Res. Develop., 8, 666 (2004);

Stability Air Sensitive
Applications Pentadecanal is found in the essential oil of verbascum thapsus. L, a species of mullein that is native to europe and is known to possess antimicrobial activitiy.
References Morteza-Semnani, K., et al.: J. Essential. Oil. Plants., 15, 373 (2012); Silva, R., et al.: Food. Chem. Toxicol., 53, 240 (2013);

Applications Silver Bromide is used in the spectroscopic study of silver halides in montmorillonite and their antibacterial activity, also used in the antimicrobial compositions for use in wound care products.
References Sohrabnezhad, S., et al.: J. Photochem. Photobiol., 163, 150 (2016); Adams, L. L., et al.: From U.S. Pat. Appl. Publ. (2016), US 20160220728 A1 20160804

Applications An epimer of L-Fructose that is a potential inhibitor of microbial activity in bovine lactoperoxidase system. A metabolite of Allitol.
References Al,-Baari, A.N. et al.: J. Food Prod., 74, 134 (2011); Carr, J.G. et al.: Phytochem., 7, 1 (1968);

Applications (Z)​-​Ethyl 2-​chloro-​2-​(2-​(4-​chlorophenyl)​hydrazono)​acetate is a reagent used in the preparation of pyrimidine and pyrimidinone-based compounds for their use as antimicrobials.
References Abbas, I et al.: J. Hetero. Chem., 54, 3447 (2017);

Stability Volatile
Applications 2,3-Dihydropyran is used in the synthesis of potent and selective myeloperoxidase inhibitors useful as antimicrobial oxidants. Also is used to synthesize novel and selective σ1 receptor ligands.
References Soubhye, J. et al.: J. Med. Chem., 56, 3943 (2013); Diaz, J. et al.: J. Med. Chem., 56, 3656 (2013);

Stability Hygroscopic
Applications α,α'-Dilaurin is a possible antimicrobial agent against gram-posistive organisms.
References Kabara, J., et al.; Antimicrob. Agents Chemother., 2, 23 (1972); Conley, A., et al.: Antimicrob. Agents Chemother., 4, 501 (1973)

Stability Moisture Sensitive
Applications 3,6-Dichlorophthalic Anhydride is an intermediate in the synthesis of phthalic compounds, phthalazines, and quinones with antimicrobial activity.
References Hansongnern, K., et al. Appl. Magnetic. Resonance., 23, 333 (2003);

Stability Light Sensitive
Applications Di-2-(Hydroxyphenyl)acetamido Cefprozil is an impurity in the synthesis of Cefprozil (C243910), semisynthetic oral cephalosporin consisting of approx. 90:10 Z/E isomeric mixture. Antibacterial.
References Jones, R.N., et al.: Diagn. Microb. Infect. Dis., 9, 11 (1988), Barbhaiya, R.H., et al.: Antimicrob. Agents Chemother., 34, 1204 (1990)

Applications 4-Chlorocinnamic Acid is a derivative of Cinnamic Acid (C442030) and plays an important role in the development of plants. 4-Chlorocinnamic Acid may also show potential antimicrobial, antioxidant, anti-inflammatory, and antitumoral activity.
References Jitareanu, A., et al.: Not. Bot. Horti. Agrobo., 39, 130 (2011)