Antivirals
Found 767 products of "Antivirals"
Rupintrivir
CAS:Rupintrivir is a peptidomimetic antiviral with action on rhinovirus 3C protease to inhibit viral replication and is used for research on rhinovirus and other viral infections.
Formula:C31H39FN4O7Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:598.28028Velpatasvir
CAS:Antiviral; Hepatitis C virus NS5A antagonistFormula:C49H54N8O8Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:883 g/molRemdesivir
CAS:GS 5734, also known as remdesivir is a nucleoside prodrug with broad spectrum antiviral activity against RNA viruses. As remdesivir / GS 5734 is a prodrug, it requires to be triphosphorylated by cellular kinases in order to compete with ATP for incorporation in newly replicated viral RNA. A major benefit of remdesivir in comparison with other antiviral nucleoside analogs is its resistance to proofreading exonucleases, which occur in coronaviruses. This means remdesivir can overcome the repair mechanism and preserve its antiviral activity. Remdesivir was reported to have a therapeutic as well as prophylactic efficacy in a mouse model infected with SARS-CoV-1.
Formula:C27H35N6O8PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:602.58 g/molNelfinavir mesylate
CAS:Anti-viral; HIV protease inhibitorFormula:C33H49N3O7S2Color and Shape:White PowderMolecular weight:663.89 g/molDarunavir Ethanolate
CAS:Darunavir is a HIV-1 protease inhibitor used orally in the treatment of patients with multi-drug resistant HIV-1 infection (Ghosh, 2007). It has also been shown to be effective against other infectious diseases such as hepatitis C virus and SARS coronavirus. Metabolized by cytochrome P450 3A (CYP3A) isoenzymes, darunavir is often administered together with ritonavir that prolongs its bioavaiability, giving a terminal elimination half-life (t1/2) of 15 hours (Back, 2008). The effect of darunavir on natural compounds such as matrix proteins and toll-like receptor activity has also been studied via high performance liquid chromatography (HPLC) experiments.
Formula:C27H37N3O7S·C2H6OPurity:Min. 95%Color and Shape:White PowderMolecular weight:593.73 g/molMaraviroc
CAS:CCR-5 chemokine receptor antagonist; inhibits HIV entry via gp120 protein
Formula:C29H41F2N5OPurity:Min. 95%Color and Shape:PowderMolecular weight:513.67 g/molOseltamivir acid
CAS:Inhibitor of viral neuraminidase enzyme, effective against influenza A and B viruses. This antiviral compound inhibits neuraminidase-mediated cleavage of host cell sialic acids, which interact with newly synthesised virions from the host cell. This prevents virion budding from the host, resulting in inhibition of virion release and viral infection overall.Formula:C14H24N2O4Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:284.35 g/molMolnupiravir
CAS:Controlled ProductEIDD 2801 is an orally bioavailable prodrug of β-D-N4-hydroxycytidine and was shown to inhibit SARS-CoV-2 replication in human airway epithelial cells. EIDD 2801 was also tested in mice infected with SARS-CoV and MERS-CoV viruses. EIDD 2801 targets the RNA-dependent RNA polymerase (RdRp) and reduces virus titer and improved pulmonary function in experimental animals when used in prophylactic and therapeutic regime.Formula:C13H19N3O7Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:329.31 g/molEfavirenz - Bio-X ™
CAS:Efavirenz is a non-nucleoside-based reverse transcriptase inhibitor (NNRTI) of the reverse transcriptase of HIV-1. It inhibits the viral enzyme reverse transcriptase by binding to its active site. In certain cell culture assays, Efavirenz showed great efficiency when inhibiting wild-type HIV-1 replication. In the treatment of HIV, Efavirenz has been studied in combination with Emtricitabine and Tenofovir disoproxil fumarate for ease of administration in some clinical studies. Recent in vitro cell studies indicated Efavirenz is a potential treatment for pancreatic, prostate and triple-negative breast cancers due to its cytotoxicity against cancer cells.Efavirenz is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C14H9ClF3NO2Purity:Min. 95%Color and Shape:PowderMolecular weight:315.67 g/molDarunavir ethanolate- Bio-X ™
CAS:Darunavir is an HIV protease inhibitor that is used in the treatment of HIV-1 infection. This drug inhibits HIV-1 protease from binding and catalyzing by attaching to the enzyme and preventing HIV replication.Formula:C27H37N3O7S·C2H6OPurity:Min. 99 Area-%Color and Shape:PowderMolecular weight:593.73 g/molCabotegravir
CAS:Anti-viral; HIV integrase inhibitorFormula:C19H17F2N3O5Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:405.35 g/molSaquinavir - Bio-X ™
CAS:Saquinavir is a HIV protease inhibitor drug that is used with other antiretroviral drugs for the treatment of HIV-1. As this drug prevents HIV protease activity, it prevents the proteolysis of the Gag polyprotein and thus results in non-infectious virus particles.
Formula:C38H50N6O5Purity:Min. 95%Color and Shape:PowderMolecular weight:670.84 g/molGS 331007
CAS:Anti-viral; RNA polymerase inhibitor; sofosbuvir metaboliteFormula:C10H13FN2O5Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:260.22 g/molRimantadine HCl - Bio-X ™
CAS:Rimantadine is an anti-viral drug that is used for the prevention of influenza A infection. This drug is an RNA synthesis inhibitor and exerts its effects on the viral replication cycle. Although not fully understood, it is said that the M2 gene may play a role in Rimantadine susceptibility.Formula:C12H22ClNPurity:Min. 95%Color and Shape:PowderMolecular weight:215.76 g/molSofosbuvir
CAS:Potent inhibitor of viral RNA polymerase called non-structural protein 5B (NS5B). This nucleotide analog is effective against Hepatitis C virus (HCV) infection since it inhibits viral RNA replication. Sofosbuvir is a prodrug and gets triphosphorylated in the liver cells, generating biologically active compound with anti-viral activity.Formula:C22H29FN3O9PPurity:Min. 95%Color and Shape:Off-White PowderMolecular weight:529.45 g/molZalcitabine - Bio-X ™
CAS:Zalcitabine (also known as dideoxycytidine or ddC) is a nucleoside analogue reverse transcriptase inhibitor (NRTI) medication used in the treatment of human immunodeficiency virus (HIV) infections. It works by blocking reverse transcriptase, an enzyme essential for replication of the HIV virus, thereby preventing the virus from multiplying and spreading. Zalcitabine is often used in combination with other antiretroviral drugs to effectively treat HIV/AIDS.Formula:C9H13N3O3Purity:Min. 95%Color and Shape:PowderMolecular weight:211.22 g/molAtazanavir sulfate
CAS:Anti-viral; HIV protease inhibitor
Formula:C38H52N6O7·H2SO4Purity:Min. 95%Color and Shape:PowderMolecular weight:802.94 g/molL-Valacyclovir HCl - Bio-X ™
CAS:Valacyclovir is a guanine nucleoside antiviral drug that is used to treat herpes exacerbations. This drug inhibits DNA polymerase and prevents viral DNA synthesis. Valacyclovir is the L-valine ester of acyclovir.Formula:C13H20N6O4·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:360.8 g/molBMS 806
CAS:BMS 806 is an antiretroviral agent and is used for the treatment of HIV. It inhibits the fusion of the HIV virus with the host cell membrane.Formula:C22H22N4O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:406.43 g/molPenciclovir - Bio-X ™
CAS:Penciclovir is an antiviral agent and acyclic guanine derivative that has proven efficient in the treatment of Herpes Simplex type 1 and 2 (HSV1 and HSV2) infection. Penciclovir is transformed by the virus into an active derivative able to block the deoxyguanosine triphosphate substrate binding site of the HSV polymerase.
Formula:C10H15N5O3Purity:Min. 95%Color and Shape:PowderMolecular weight:253.26 g/mol
