Flavonoids

<p>3,7,4-Trihydroxy-5-methoxy-8-prenylflavanone, (2R,3S), is a prenylated flavanone, which is a type of polyphenolic compound. This compound is typically derived from various plant sources, particularly those that produce flavonoids as secondary metabolites. Its structure is characterized by the presence of hydroxyl and methoxy groups, as well as a prenylated side chain, which contribute to its physicochemical properties.</p>

<p>(S)-Hesperetin is a flavonoid compound, which is a naturally occurring polyphenolic structure. It is predominantly derived from citrus fruits, including oranges and lemons, through the metabolic breakdown of its glycoside form, hesperidin. This transformation occurs in the human body, where hesperidin is hydrolyzed to release hesperetin and other metabolites.</p>

<p>Prunetin-4'-glucoside is a specialized flavonoid compound, categorized as a glucoside, which is derived from natural plant sources. This glycosylated form of prunetin is found in various plants and serves as part of the plant's defense mechanism. Its mode of action involves antioxidative properties that neutralize free radicals, thus protecting cellular structures from oxidative damage. This mechanism is crucial as oxidative stress is implicated in numerous diseases.</p>

<p>4'-O-Methyllicoflavanone is a flavonoid compound, which is a naturally occurring chemical typically found in various plants. It belongs to a class of secondary metabolites known for their wide array of biological activities. The source of 4'-O-Methyllicoflavanone is primarily from plant species, where it serves as a part of the plant’s defense mechanism against environmental stressors and pathogens.</p>

<p>8-Chloroflavanone is a synthetic flavonoid derivative, which is primarily obtained through chemical synthesis involving the chlorination of flavanone substrates. Its mode of action involves the modulation of various biological pathways, including potential inhibition of specific enzymes and interaction with receptor sites, which may influence cellular signaling mechanisms.</p>

<p>7-Hydroxy-5,8-dimethoxyflavanone is a naturally occurring flavanone, which is a subcategory of flavonoids commonly found in various plants. This compound is derived from plant sources, often isolated during phytochemical studies examining the secondary metabolites produced by flora. The mode of action of 7-Hydroxy-5,8-dimethoxyflavanone involves modulating various biochemical pathways, potentially influencing enzymatic activity and signal transduction mechanisms. This flavanone has garnered scientific interest due to its reported bioactive properties, such as antioxidant and anti-inflammatory effects. <br><br>Uses and applications of 7-Hydroxy-5,8-dimethoxyflavanone are primarily in research settings, where it is utilized to explore its potential therapeutic benefits. Scientists investigate its efficacy in cell culture and animal models to better understand its effects on human health. Research is ongoing to assess its potential applications in developing nutraceuticals or pharmaceuticals, particularly in areas concerning oxidative stress and inflammation-related disorders. The exploration of its pharmacokinetic properties, safety profile, and bioavailability remains an active area of scientific inquiry.</p>

<p>Carlinoside is a bioactive flavonoid glycoside, which is typically sourced from plants of the Astraceae family, specifically from the genus Carlina. As a natural phytochemical, its mode of action involves the modulation of various biochemical pathways, primarily through its antioxidant properties and potential to interact with cellular oxidative stress mechanisms.</p>

<p>Steppogenin is a metabolic modulator, which is derived from natural plant sources known for their enzymatic properties. Its mode of action involves the induction of cytochrome P450 enzymes, facilitating various oxidative reactions within biological systems. As an enzyme inducer, Steppogenin modulates metabolic pathways, making it invaluable for the study of drug metabolism and pharmacokinetics.</p>

<p>Limocitrin is a flavonoid compound, which is a naturally occurring plant secondary metabolite. Flavonoids are widely distributed in the plant kingdom and are known for their diverse biological activities. Limocitrin, specifically, has been isolated from various plant sources, including certain fruits and flowers. Its mode of action involves interacting with cellular signaling pathways, affecting processes such as oxidative stress response and gene expression regulation.</p>

<p>Glyasperin C is a bioactive compound derived from Glycyrrhiza uralensis, commonly known as liquorice. This product is a phytochemical isolated from the roots of the liquorice plant, a member of the Fabaceae family. Glycyrrhiza uralensis has been traditionally utilized in various medicinal practices, primarily due to its diverse range of biologically active constituents.</p>

<p>(S)-4',7-Dimethyl equol is an isoflavandiol, which is a metabolite of the soy isoflavone daidzein. It is produced in the human gut by bacterial metabolism, provided the individual has the appropriate intestinal microbiota capable of this transformation. The compound exhibits estrogenic activity, primarily due to its structural similarity to the endogenous hormone 17β-estradiol, allowing it to bind to estrogen receptors.</p>

<p>3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone, (2R,3S)- is a naturally occurring prenylated flavanone, which is primarily sourced from various plant species. This compound is part of the larger flavonoid family and is often found in certain medicinal plants known for their wide range of therapeutic properties. Its structure comprises a flavanone backbone, modified by hydroxyl, methoxy, and prenyl groups that contribute to its distinctive chemical profile.</p>

<p>(E)-Deschlorophenyl fluoxastrobin is a synthetic fungicide, which is derived from the strobilurin class of compounds, originally sourced from natural fungal metabolites. It functions by inhibiting mitochondrial respiration in fungal cells through disruption of the cytochrome bc1 complex, specifically at the Qo site. This mode of action effectively curtails the energy supply of the pathogen, leading to its death, and is integral in managing resistance issues known to occur with other fungicide groups.</p>

<p>6,2',4'-Trimethoxyflavone is a flavonoid compound, which is a type of phytochemical found in various plant species. It is derived from natural sources, including certain medicinal herbs and plants known for their bioactive properties. This specific flavone is characterized by its three methoxy groups attached at distinct positions on the flavonoid backbone, which confer unique chemical properties and biological activities.</p>

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<p>2-Hydroxynaringenin is a flavonoid compound, which is derived from the extraction and purification of various citrus fruits, particularly from the peel and pulp. It belongs to a class of secondary metabolites found predominantly in these plants, functioning as part of their natural defense mechanism.</p>

<p>5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavanone is a specialized flavanone derivative, which is a type of plant secondary metabolite found in various botanical sources. This compound originates primarily from citrus fruits and certain medicinal plants where it contributes to the plant’s defense mechanisms. As a flavonoid, its mode of action involves the modulation of enzyme activity, interaction with cell membranes, and potential antioxidant properties, allowing it to scavenge free radicals and reduce oxidative stress.</p>

<p>Bilobetin is a flavonoid compound, which is sourced from the leaves of the Ginkgo biloba tree. This compound primarily functions through its antioxidative properties, influencing a variety of neural pathways. Its mode of action involves the scavenging of reactive oxygen species and modulation of cellular signaling pathways that impact synaptic transmission and neuroplasticity.</p>

<p>2,3-Dihydrohinokiflavone is a natural bioflavonoid compound, which is typically derived from various plant sources, particularly those native to East Asia. This compound belongs to the broader flavonoid family, known for their antioxidant properties. Its mode of action involves modulating various signaling pathways, which can lead to anti-inflammatory and antioxidant effects. It achieves this by inhibiting the production of pro-inflammatory cytokines and scavenging free radicals, thus reducing oxidative stress in biological systems.</p>

<p>Kaempferol-3,7-di-O-glucoside is a naturally occurring flavonoid, which is commonly derived from various plant sources, including fruits, vegetables, and medicinal herbs. As a flavonoid, it appears predominantly in the form of glycosides, where kaempferol is conjugated with sugar moieties, enhancing its solubility and bioavailability.</p>

<p>(2R)-5,7-Dimethoxyflavanone is a natural flavonoid, which is a type of polyphenolic compound. It is derived from various plant sources, commonly found in fruits, vegetables, and certain medicinal herbs. Its structure includes a flavanone backbone with methoxy groups at specific positions, which modulate its biological activity.</p>

<p>6-Methoxykaempferol 3-O-rutinoside is a flavonoid glucoside, which is derived from various plants, particularly those belonging to the Leguminosae family. This compound is of significant interest due to its potential biological activities and natural occurrence. The mode of action of 6-Methoxykaempferol 3-O-rutinoside primarily involves its antioxidant properties, which may help in neutralizing free radicals and reducing oxidative stress in biological systems.</p>

<p>Protogenkwanin 4'-glucoside is a flavonoid glucoside, which is a naturally occurring compound derived from various plant sources, particularly known to be present in certain medicinal herbs used in traditional medicine. As a flavonoid glucoside, it interacts with biological systems primarily through its antioxidant properties, which help in scavenging free radicals and reducing oxidative stress. This mode of action is crucial in mitigating cell damage and inflammation.</p>

<p>Homoferreirin is a biochemical siderophore, which is a low-molecular-weight iron-chelating compound derived from plant sources. Its mechanism of action involves binding ferric iron (Fe^3+) ions with high affinity, forming a stable complex. This complex aids in the solubilization and transport of iron across cellular membranes, which is crucial in environments where iron availability is limited, such as in soil and certain biological niches.</p>

<p>2',7-Dihydroxy-5,8-dimethoxyflavanone is a natural flavanone, which is a type of polyphenolic compound. It is derived from various plant sources where flavonoids are commonly found, such as fruits, vegetables, and certain herbs. This particular flavanone exhibits a unique chemical structure characterized by dihydroxy and dimethoxy functional groups, which contribute to its biological activity.</p>

<p>3,5,7,2',6'-Pentahydroxyflavanone is a flavonoid derivative, which is a type of polyphenolic compound known for its potential health benefits. Typically sourced from various plants, flavonoids like 3,5,7,2',6'-Pentahydroxyflavanone are abundant in fruits, vegetables, and certain medicinal herbs. The mode of action of this compound primarily involves its ability to exert antioxidant and anti-inflammatory effects. It achieves this by scavenging free radicals and modulating pathways associated with oxidative stress and inflammation.</p>

<p>Genistein 7,4'-di-O-glucoside is a naturally occurring isoflavone glucoside, which is derived from plant sources such as soybeans and other legumes. As an isoflavone, it belongs to a class of phytoestrogens, compounds that are structurally similar to estrogens but are derived from plants. The mode of action of Genistein 7,4'-di-O-glucoside primarily involves its ability to interact with estrogen receptors in the body, exhibiting both estrogenic and anti-estrogenic effects depending on the physiological context. This interaction can modulate various signaling pathways, potentially impacting cellular growth, apoptosis, and differentiation.</p>

<p>Leucoside is a biochemical compound, which is derived from activated human leucocytes. This product is obtained through a meticulous extraction process that isolates specific bioactive molecules. Its mode of action involves the modulation of immune responses, potentially by influencing cytokine signaling pathways. Leucoside interacts with immune cells, potentially enhancing or dampening specific activities to achieve desired immunomodulatory effects.</p>

<p>Licoflavonol is a bioactive compound that serves as an antioxidant, which is derived from plant sources, particularly flavonoid-rich species. Its mode of action involves scavenging free radicals and modulating pathways involved in oxidative stress and inflammation. By reducing oxidative damage, Licoflavonol can stabilize cellular environments and protect macromolecules such as DNA, proteins, and lipids from degenerative changes.</p>

<p>Sophoraflavanone C is a flavonoid compound, which is derived from the root of the Sophora flavescens plant. This natural product is categorized as a prenylated flavonoid, a group known for diverse biological activities. Sophoraflavanone C exerts its effects through multiple modes of action, including the inhibition of microbial growth and anti-inflammatory pathways. Its antimicrobial properties are attributed to the disruption of bacterial cell walls and inhibition of critical microbial enzymes. Additionally, its anti-inflammatory effects are mediated by the suppression of pro-inflammatory cytokines and inhibition of key signaling pathways such as NF-kB.</p>

<p>7,4'-Dibenzyl daidzein is a synthetic isoflavonoid, derived from the modification of natural isoflavones commonly found in soy products. These isoflavones are known for their estrogenic activity and potential therapeutic benefits. The source of inspiration for this compound lies in natural phytoestrogens, which exhibit significant interaction with human estrogen receptors. This synthetic analog is designed to enhance specific bioactivities beyond those of its natural counterparts.</p>

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<p>Enhances TRAIL-induced apoptosis in MOLT-4- cells</p>

<p>R,S equol 4'-sulfate sodium salt is a synthetic derivative of equol, which is a type of flavonoid metabolite. This compound is primarily sourced from the biotransformation of the isoflavone daidzein through gut microbiota activity. As a sulfate salt, it is more soluble in aqueous environments, which may facilitate its use in various biological contexts.</p>

<p>7,4'-Dihydroxyhomoisoflavanone is a naturally occurring compound, classified as a homoisoflavanone, which is a type of polyphenolic compound. It is primarily sourced from plants, specifically found in certain species of the Fabaceae family. The compound is characterized by its unique structural configuration, which contributes to its bioactivity.</p>

<p>6-Methoxy-3,5,7,4'-tetrahydroxyflavone is a natural flavonoid derivative, which is primarily sourced from various plants known for their high polyphenolic content. It plays a significant role in the plant's defense mechanism due to its ability to scavenge free radicals and protect against oxidative stress. This compound exerts its mode of action through its potent antioxidant and anti-inflammatory capabilities, primarily by modulating signaling pathways and inhibiting the activity of enzymes involved in inflammation.</p>

<p>Maackiaflavanone is a specialized flavanone, which is a type of natural compound. It is derived from the Maackia plant species, particularly found in temperate regions and known for its rich phytochemical profile. The flavanone exhibits its activity primarily through its interaction with cellular pathways associated with oxidative stress and inflammation, modulating various biochemical signals that can influence cell behavior.</p>

<p>Lupinalbin B is a bioactive compound, specifically classified as an alkaloid, which is derived from the seeds of the Lupinus plant species. These plants, commonly known as lupins, are a part of the legume family and are cultivated primarily for their seeds that contain high protein content. The presence of alkaloids like Lupinalbin B in lupin seeds is a result of the plant's secondary metabolism, which serves various ecological functions, including defense against herbivores.</p>

<p>5,6,7,2'-Tetrahydroxyflavone is a naturally occurring flavonoid, which is commonly found in various plants. As a bioactive compound, it is typically derived from the leaves, stems, or fruits of these plants, where it plays a crucial role in plant defense. The mode of action of 5,6,7,2'-Tetrahydroxyflavone is primarily through its potent antioxidant activity. It scavenges free radicals and reduces oxidative stress, thereby contributing to cellular protection and stability.</p>

<p>Osajin is a natural flavonoid compound, which is derived from the fruit of Maclura pomifera, also known as the Osage orange. This compound is characterized by its distinctive isoflavone structure, which is central to its biological activity. The mode of action of Osajin involves modulation of various biochemical pathways, predominantly exhibiting antioxidant properties. It acts by scavenging free radicals and enhancing cellular defense mechanisms against oxidative stress, thereby contributing to its potential therapeutic efficacy.</p>

<p>5-Hydroxy-7,8-dimethoxyflavone is a naturally occurring flavonoid compound, which is typically isolated from plant sources, most notably citrus fruits. The compound functions primarily as a modulator of various biological pathways through its interaction with enzyme systems and receptor sites. This includes the modulation of signaling pathways involved in inflammation, oxidative stress, and cellular apoptosis.</p>

<p>Euchrestaflavanone A is a naturally occurring flavanone, which is a type of polyphenolic compound. It is sourced from plants, specifically derived from the roots of Euchresta formosana, a species used traditionally in herbal medicine. The mode of action of Euchrestaflavanone A involves its interaction with various molecular pathways, influencing antioxidant activity and modulating enzyme function. It exhibits bioactive properties, including anti-inflammatory, antioxidant, and potential anticancer effects.</p>

<p>Europetin is a flavonoid, a type of naturally occurring compound, which is derived from various plant sources. The compound functions as an anti-inflammatory agent by modulating signaling pathways involved in inflammatory responses, such as the NF-kB pathway. Its efficacy in reducing inflammatory mediators makes it a subject of interest for exploring therapeutic interventions.</p>

<p>Biochanin A-7-O-glucoside is a naturally occurring isoflavone glucoside, which is derived from various plants, particularly red clover and soy. It is a secondary metabolite, commonly found in legumes and other related species. The mode of action of Biochanin A-7-O-glucoside involves its structural ability to act as an antioxidant, scavenging free radicals and mitigating oxidative stress. This biochemical property allows it to influence various molecular pathways related to cell signaling and gene expression.</p>

<p>Plantanone B is a naturally-derived compound, which is an anti-inflammatory agent sourced from the Plantago species. It is known for its distinct bioactive properties attributed to its unique phytochemical structure. The compound primarily functions by modulating inflammatory pathways, specifically targeting the downregulation of pro-inflammatory cytokines and inhibiting the production of reactive oxygen species. This mode of action underscores its potential in addressing inflammation-associated cellular processes.</p>

<p>Podospicatin is a type of natural compound, which is derived from fungal sources. This unique compound is isolated from specific fungal species known for their ability to produce bioactive secondary metabolites. Podospicatin is characterized by its distinctive molecular structure, which contributes to its potential bioactivity.</p>

<p>Datiscin is a flavonoid glycoside, which is a type of naturally occurring compound found in plants. It is derived from various botanical sources, notably within the Datisca genus. These compounds are characterized by a flavonoid core structure bonded to sugar moieties. The mode of action of Datiscin primarily involves its interaction with free radicals and reactive oxygen species, suggesting potential antioxidative properties. This mechanism can help mitigate oxidative stress within biological systems.</p>

<p>5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-o-beta-D-glucopyranoside is a flavanone glycoside, which is a type of naturally occurring polyphenolic compound. This compound is typically derived from various plant sources, particularly those used in traditional medicine.</p>

<p>Pinobanksin acetate is a flavonoid compound, which is naturally sourced from bee propolis. Propolis, a resinous substance collected by bees from tree buds, is renowned for its complex chemical composition integrated from various botanical sources. Pinobanksin acetate is one of the active polyphenolic constituents identified within propolis, exhibiting intriguing bioactive properties.</p>

<p>Aromadendrin 7-O-methyl ether is a flavonoid compound, which is a type of bioactive molecule. It is sourced primarily from plant materials, where it occurs naturally as a secondary metabolite. The mode of action of Aromadendrin 7-O-methyl ether involves interaction with various biological pathways, potentially affecting enzyme activity and cell signaling mechanisms. Such interactions may contribute to its reported antioxidant and anti-inflammatory properties.</p>