
Lipids
Subcategories of "Lipids"
- Fatty Acids and Derivatives(3,302 products)
- Glycerolipids(97 products)
- Glycerophospholipids / Phospholipids(383 products)
- Isoprenes / Phenyl Lipids(544 products)
- Physiologically Active Lipids(3,416 products)
- Polyketides(533 products)
- Sphingolipids(225 products)
- Sterols(198 products)
Found 1428 products of "Lipids"
7-Keto-3alpha,12-alpha-dihydroxycholanic Acid
CAS:Controlled ProductFormula:C24H38O5Color and Shape:Off White SolidMolecular weight:406.56(S)-(-)-Canadine
CAS:Applications (S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.
References Sun, H. et al.: Bioorg. Med. Chem., 21, 856 (2013); Deeb, O., et al.: Chem. Biol. Drug Des., 76, 255 (2010); Sun., et al.: Br. J. Pharmcol., 158, 1302 (2009); Duchowicz, P., et al.: Bioorg. Med. Chem., 14, 5876 (2006); Yamahara, J. et al.: Chem. Pharm. Bull., 24, 1909 (1976)Formula:C20H21NO4Color and Shape:NeatMolecular weight:339.38Glycoursodeoxycholic Acid
CAS:Applications A metabolite of Ursodeoxycholic Acid, which is used as an anticholelithogenic.
Formula:C26H43NO5Color and Shape:White To Off-WhiteMolecular weight:449.62(R)-Butyryl Carnitine Chloride
CAS:Controlled ProductStability Hygroscopic
Applications (R)-Butyryl Carnitine is a potential prodrug of Carnitine, used for treating seizure disorders.
References Fei, Y., et al.: J. Biol. Chem., 275, 23707 (2000), Duran, J., et al.: J. Membr. Biol., 185, 65 (2002), Brown, A., et al.: J. Biol. Chem., 278, 11312 (2003), Gupta, N., et al.: Life Sci., 78, 2419 (2006),Formula:C11H22NO4·ClColor and Shape:NeatMolecular weight:267.75Glyceryl Trinonadecanoate
CAS:Controlled ProductApplications Glyceryl Trinonadecanoate is used in the study of Polymorphism and transformation energetics of saturated monoacid triglycerides.
References Hagemann, J., et al.: JAOCS, 60, 1123 (1983)Formula:C60H116O6Color and Shape:White To Off-WhiteMolecular weight:933.559(R)-3-Hydroxy Myristic Acid
CAS:Controlled ProductApplications One of two major component of bacterial Lipid A .
References Jenske, R., et al.: J. Agric. Food Chem., 56, 11578 (2008), Six, D., et al.: Biochem., 47, 8623 (2008),Formula:C14H28O3Color and Shape:NeatMolecular weight:244.37(2a,3b)-2,3-Dihydroxy-urs-12-en-28-oic Acid
CAS:Controlled ProductApplications (2α,3β)-2,3-Dihydroxy-urs-12-en-28-oic Acid influences inflammatory gene expression regarding inflammatory bowel disease. In addition, its extracted from the plants Gentiana farreri and shows anti-tumor activity
References Mueller, D. et al.: Food Chem., 139, 339 (2013); Thilakarathna, S. et al.: Food Chem., 138, 463 (2013); Yang, A. et al.: Adv. Mat. Res., 554, 1682 (2012);Formula:C30H48O4Color and Shape:NeatMolecular weight:472.7(3β,5β)-3-Hydroxycholan-24-oic acid
CAS:Applications (3β,5β)-3-Hydroxycholan-24-oic acid has been used for the study of the activation of β1 subunit-containing BK channels with respect to the structure of monohydroxylated bile acids.
References Bukiya, A.N., ey al.: J. Lipid. Res., 49, 2441-2451 (2008)Formula:C24H40O3Color and Shape:NeatMolecular weight:376.578-Dehydrocholesterol
CAS:Applications 8-Dehydrocholesterol is an intermediate in the synthesis of Zymostenol, which is the derivative of Zymosterol (Z701520), an sterol intermediate in the biosynthesis of cholesterol (C432501).
References Roland, E.D., et al.: J. Am. Chem. Soc., 111, 278 (1989); Echevarria, F., et al.: J. Biol. Chem., 265, 8484 (1990); Baranovskii, A.V., et al.: Russian. J. Bioorg. Chem., 28, 250 (2002); Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934);Formula:C27H44OColor and Shape:NeatMolecular weight:384.64Sodium Oleate
CAS:Controlled ProductApplications Sodium oleate (cas# 143-19-1) is a useful research chemical.
Formula:C18H33NaO2Color and Shape:NeatMolecular weight:304.44C24:1 Ceramide
CAS:Controlled ProductApplications Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of phospholipase C, appropriately named sphingomyelinase.
References Gu, Q, et al.: Anal. Biochem., 244, 347 (1997), Perry, D.K., et al.: Trends Cardiovasc. Med., 6, 158 (1996), Clayton, R.B., et al.: J. Lipid Res., 15, 557 (1974),Formula:C42H81NO3Color and Shape:NeatMolecular weight:648.13b,5a,6b-Trihydroxycholestane
CAS:Applications Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity.
References Watson, K., et al.: J. Clin. Invest., 93, 2106 (1994), Wada, T., et al.: Circ. Res., 84, 166 (1999), Engelse, M., et al.: Cardiovasc. Res., 52, 281 (2001), Landis, M., et al.: J. Biol. Chem., 277, 4713 (2002),Formula:C27H48O3Color and Shape:NeatMolecular weight:420.67D-erythro-Sphingosylphosphorylcholine (Synthetic)
CAS:Controlled ProductApplications Involved in cell regulation, and transmembrane signaling. A putative lipid second messenger, connected via Protein Kinase C to the phosphatidylinositol-derived second messengers for signal transduction.
References Kratzer, B. and Schmidt, R.R.: Liebigs Ann., 955-963 (1995)Formula:C23H49N2O5PColor and Shape:NeatMolecular weight:464.62(11Z)-11-Eicosenoic Acid
CAS:Applications (11Z)-11-Eicosenoic Acid, is a monostaturated fatty acid. The combined C20:1 isomers constitute 70% of the total fatty acid pool in jojoba seed oil isolated from plants in the Arizona desert.
References Miwa, T.K. et al.: J. Am. Chem. Soc. 48(6), 259-264 (1971).;Formula:C20H38O2Color and Shape:White To Off-WhiteMolecular weight:310.5112-Hydroxystearic Acid
CAS:Controlled ProductApplications 12-Hydroxystearic Acid is used in edible vegetable oils and organogels.
References Rogers, M. et al.: Soft. Matt., 4, 1483 (2008); Hughes, N. et al.: Trends. Food. Sci. Tech., 20, 470 (2009);Formula:C18H36O3Color and Shape:White To BeigeMolecular weight:300.48C6 Ceramide
CAS:Controlled ProductApplications A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.
References Liu, Z., et al.: J. Neurochem., 106, 2463 (2008), Heakal, Y., et al.: Mol. Cancer Res., 7, 724 (2009), Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009), Mahdy, A., et al.: Mol. Ther., 17, 430 (2009),Formula:C24H47NO3Color and Shape:White To Off-WhiteMolecular weight:397.63β-Sitosterol-d7 (mixture of diasteromers)
CAS:Controlled ProductApplications Labelled Sitosterol (S497050). A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma.
References Tanaka, et al.: J. Biochem., 17, 483 (1933), Nigro, N.D., et al.: J. Natl. Cancer Inst., 69, 103 (1982),Formula:C29D7H43OColor and Shape:NeatMolecular weight:421.75Allolithocholic acid
CAS:Controlled ProductApplications Allolithocholic acid is used as steroid compound as T regulatory lymphocyte modulators and uses for treatment of inflammatory or autoimmune disorders.
References Littman, D. R., et al.: PCT Int. Appl. 160pp. (2020)Formula:C24H40O3Color and Shape:NeatMolecular weight:376.58(-)-Thujopsene (>85%)
CAS:Controlled ProductFormula:C15H24Purity:>85%Color and Shape:ColourlessMolecular weight:204.35(R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole
CAS:Controlled ProductApplications (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole (THI) inhibits sphinogosine-1-phosphate (S1P) lyase for treatment of autoimmune disorders.
References Zhang, H., et al.: Tetrahedron, 69, 4041 (2013); Bagdanoff, J.T., et al.: J. Med. Chem., 53, 8650 (2010); Bagdanoff, J.T., et al.: J. Med. Chem., 52, 3941 (2009)Formula:C9H14N2O5Color and Shape:White To Light BrownMolecular weight:230.22(1S,4S)-N-Desmethyl Sertraline Hydrochloride
CAS:Formula:C16H15Cl2N·ClHColor and Shape:White SolidMolecular weight:328.66Glycocholic Acid
CAS:Applications Glycocholic Acid (cas# 475-31-0) is a useful research chemical.
Formula:C26H43NO6Color and Shape:Off-WhiteMolecular weight:465.62Stearoyl L-a-Lysolecithin
CAS:Stability Hygroscopic, moisture sensitive
Applications Stearoyl L-α-Lysolecithin is an bioactive lysophosphatidylcholine derived compound found to be released by bronchial epithelial cells. Stearoyl L-α-Lysolecithin have also been utilized in the development of liposomes and michelles by drug transdermal delivery devices.
References Zhuge, Y., et al.: Allergy Asthma Immunol Res., 6, 66 (2014)Formula:C26H54NO7PColor and Shape:NeatMolecular weight:523.68Decanoyl-L-carnitine Chloride
CAS:Controlled ProductStability Hygroscopic
Applications Decanoyl-L-carnitine Chloride is a metabolite of L-Carnitine (C184110); an essential cofactor of fatty acid metabolism. Also required for the transport of fatty acids through the inner mitochondrial membrane.
References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978); Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001); Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002); Karlic, H., et al.: Nutrition, 20, 709 (2004)Formula:C17H34ClNO4Color and Shape:NeatMolecular weight:351.91Lithocholic Acid-d4
CAS:Controlled ProductApplications A labelled cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.
References Brindle, J., et al.: Nat. Med., 12, 1439 (2002), Lindon, J., et al.: Biomarkers, 9, 1 (2004), Holmes, E., et al.: Cell, 134, 714 (2008),Formula:C242H4H36O3Color and Shape:Off-WhiteMolecular weight:380.6Phytantriol
CAS:Controlled ProductApplications Phytantriol 74563-64-7 (cas# 74563-64-7) is a useful research chemical.
Formula:C20H42O3Color and Shape:NeatMolecular weight:330.55(5Z)-5-Dodecenoic Acid
CAS:Controlled ProductStability Light Sensitive
Applications (5Z)-5-Dodecenoic acid is a fatty acid and a component of the essential oils of certain plants, such as Paeonia lactiflora Pall., and is used as biofuel.
References Liu, P.; et al.: Industrial Crops and Products, 107, 260 (2017); Xu, L.; et al.: Renewable Energy, 130, 910 (2019).Formula:C12H22O2Color and Shape:NeatMolecular weight:198.321-Deoxy Cortisone
CAS:Controlled ProductApplications A Cortisone derivative, a glucocorticoid.
References Mickelson, K., et al.: Biochemistry, 20, 6211 (1981), Westphal, U., et al.: J. Steroid Biochem., 19, 1 (1983),Formula:C21H28O4Color and Shape:NeatMolecular weight:344.44Lithocholic Sulfate Disodium Salt
CAS:Controlled ProductFormula:C24H38Na2O6SColor and Shape:NeatMolecular weight:500.6(-)-Maackiain
CAS:Controlled ProductApplications (-)-Maackiain (CAS# 2035-15-6) is a useful research chemical compound.
Formula:C16H12O5Color and Shape:White To Off-WhiteMolecular weight:284.2619-Hydroxy Cholesterol
CAS:Applications A metabolite of Cholesterol. Cholesterol oxidation product having cytotoxicity effects.
References Higley, N., et al.: Food Chem. Toxicol., 22, 983 (1984), Emanuel, H., et al.: J. Food Sci., 56, 843 (1991), Kilsdonk, E., et al.: J. Lipid Res., 36, 505 (1995), Cantwell, H., et al.: Cell Biol. Toxicol., 14, 401 (1998),Formula:C27H46O2Color and Shape:NeatMolecular weight:402.6510-Hydroxydecanoic Acid
CAS:Applications 10-Hydroxydecanoic Acid plays a crucial role in the cellular signal transduction in immune responses. Modulates innate immune response affecting the toll-like receptors (TLRs) which play a crucial role in the immunity and recognizing pathogen associated molecular patterns.
References Takahashi, K. et al.: Biomed. Res., 34, 205 (2013); O'Connor, S. et al.: Biomat., 34, 2710 (2013);Formula:C10H20O3Color and Shape:NeatMolecular weight:188.264Isodeoxycholic Acid
CAS:Controlled ProductApplications Isodeoxycholic Acid is used for comprehensive bile acid profiling in hereditary intrahepatic cholestasis.
References Liu, T., et al.: Liver Int. 38, 1676 (2018)Formula:C24H40O4Color and Shape:White To Off-WhiteMolecular weight:392.58Oleanolic Acid
CAS:Applications A triterpenoid known for its anti-inflammatory properties, is commonly present in several medicinal plants. Inhibits secretory phospholipase A2.
References Andrikopoulos, N., et al.: J. Med. Food, 5, 1 (2002), Lanteri, S., et al.: Food Chem., 76, 501 (2002), Rodriguez-Rodriguez, R., et al.: Br. J. Pharmacol., 155, 535 (2008), Sotiroudis, T., et al.: Eur. J. Nutr, 47, 69 (2008),Formula:C30H48O3Color and Shape:White To Off-WhiteMolecular weight:456.75b-Cholanic Acid-3a,6b-diol
CAS:Controlled ProductApplications 5β-Cholanic Acid-3α, 6β-Diol is a cholesterol derivative; Plasma lipophilic biomarkers in rats. Also, it is one of two major metabolites from the hydroxylation of hepatic lithocholic acid catalyzed by Cyp3a/Cyp3a11 enzymes in mice.
References Mayengbam, S., et al.: Eur. J. Nutr., 55, 1213-1223 (2016); Hrycay, E., et al.: Mol. Cell. Biochem., 389, 119-132 (2014)Formula:C24H40O4Color and Shape:White To Off-WhiteMolecular weight:392.587ß-Hydroxycholesterol-d7
CAS:Controlled ProductApplications 7ß-Hydroxycholesterol-d7 is a standard used in the simultaneous measurement of F2-isoprostane, hydroxyoctadecadienoic acid, hydroxyeicosatetraenoic acid, and hydroxycholesterols in plasma and liver of hepatitis patients.
References Yoshida, Yasukazu., Analytical Biochemistry, 379, 105-115, (2008)Formula:C272H7H39O2Color and Shape:NeatMolecular weight:409.7Brassicasterol
CAS:Applications A phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway.
References Bishop, G.J., et al.: Plant Cell Physiol. 42, 114, (2001), Fernandez, C., et al., Biochem. J. 366, 109 (2002),Formula:C28H46OColor and Shape:WhiteMolecular weight:398.661,2-Dioleoyl-3-linoleoyl-rac-glycerol
CAS:Formula:C57H102O6Purity:>90%Color and Shape:NeatMolecular weight:883.42(±)-Tuberonic Acid (~90%)
CAS:Controlled ProductApplications (±)-Tuberonic Acid can be used in biological activity and study for structure-activity relations of substituted, deleted or stereospecifically altered jasmonic acid in gene expression of barley leaves. It can be used and tested to find the structural requirements which induce the expression of jasmonate-responsive genes in barley.
References Miersch, O., et al.: Phytochemistry, 50, 353-361 (1998)Formula:C12H18O4Purity:~90%Color and Shape:NeatMolecular weight:226.271-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
CAS:Controlled ProductApplications 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one is an antioxidant and also has anti cancer effects on human breast cancer MCF-7 cells and Hep3B human hepatocellular carcinoma cells.
References Choi, Eun Jeong, et al.: Mol. Med. Rep., 9(1), 328-332 (2014);Choi, Eun Jeong, et al.: Onco.Lett., 6(6), 1784-1788 (2013);Choi, Eun Jeong, et al.: Inter. J.of Mol. Med., 31(3), 726-730 (2013)Formula:C15H14O4Color and Shape:NeatMolecular weight:258.27Glycolithocholic Acid Sodium Salt
CAS:Applications Glycolithocholic Acid Sodium Salt is a bile salt and may induce calcium uptake in human erythrocytes.
References Oelberg, D.G., et al.: Hepatology, 7 245-52 (1987);Formula:C26H42NNaO4Color and Shape:NeatMolecular weight:455.61(25R)-26-Hydroxy-cholest-4-en-3-one
CAS:Controlled ProductApplications (25R)-26-Hydroxy-cholest-4-en-3-one is an oxygenated sterol which has many important biological activities. (25R)-26-Hydroxy-cholest-4-en-3-one has been used as a reactant for the synthesis of other sterols.
References Li, S., et. al.: Chem. Phys. Lipids, 99, 33 (1999); Khripach, V., et. al.: Steroids, 70, 551 (2005)Formula:C27H44O2Color and Shape:NeatMolecular weight:400.6424(R/S)-Hydroxycholesterol-d7
CAS:Controlled ProductApplications 24(R/S)-Hydroxycholesterol-d7 is used in the study of biochemical methods for quantitative detection of steroids containing quantitative charge tags and oxidizing agents and using mass spectroscopy for detection.
References Groffoths, Williams., US 20150233953, (2015)Formula:C272H7H39O2Color and Shape:NeatMolecular weight:409.7(+/-)-N-3-Benzylnirvanol
CAS:Controlled ProductApplications It is a potent and selective human CYP2C19 inhibitor.
References Suzuki, H., et al.: Drug Metab. Dispos., 30, 235 (2002), Robert, L., et al.: Drug Metab. Dispos., 31, 343 (2003),Formula:C18H18N2O2Color and Shape:NeatMolecular weight:294.35Desmosterol-d6
CAS:Controlled ProductApplications A labelled metabolite of Cholesterol (C432501).
References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),Formula:C272H6H38OColor and Shape:NeatMolecular weight:390.67Ursocholic Acid
CAS:Controlled ProductImpurity Ursodeoxycholic Acid EP Impurity D
Applications Ursocholic Acid (Ursodeoxycholic Acid EP Impurity D) is an Ursodeoxycholic Acid (U850000) impurity.
References Ward, A., et al.: Drugs, 1984, 27, 95 (1984), Sama, C., et al.: Clin. Drug Invest., 13, 192 (1997), Nobilis, M., et al.: J. Pharm. Biomed. Anal., 24, 937 (2001),Formula:C24H40O5Color and Shape:White To BeigeMolecular weight:408.57alpha-Phellandrene (Technical Grade)
CAS:Formula:C10H16Color and Shape:ColourlessMolecular weight:136.23Chenodeoxycholic acid
CAS:Controlled ProductImpurity Ursodeoxycholic Acid EP Impurity A
Applications Chenodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity A) is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Facilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.
References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986),Formula:C24H40O4Color and Shape:BeigeMolecular weight:392.57Glycidol
CAS:Controlled ProductApplications Stabilizer in manufacturing of vinyl polymers; intermediate in synthesis of glycerol, glycidyl ethers, and amines; additive for oil and synthetic hydraulic fluids; epoxy resin diluent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hiles, R.A., et al.: Food Cosmet. Toxicol., 19, 347 (1981); Thompson, E.D., et al.: Food Chem. Toxicol., 22, 665 (1984);Formula:C3H6O2Color and Shape:ColourlessMolecular weight:74.08(E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)acrylaldehyde
CAS:Stability Air Sensitive
Applications (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)acrylaldehyde (cas# 4206-58-0) is a useful research chemical.Formula:C11H12O4Color and Shape:NeatMolecular weight:208.211,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) (Sodium Salt)
CAS:Controlled ProductApplications 1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) (Sodium Salt), is used in the production of micelles, liposomes, and other type of artificial membranes.
References Rodrigues, C., et al.: Biophys. Chem, 94, 97 (2001); Van Dijck, P.W., et al.: Biochim. Biophys. Acta., 406, 465 (1975)Formula:C34H66O10P·NaColor and Shape:NeatMolecular weight:688.85Cholesterol 5alpha,6alpha-Epoxide
CAS:Controlled ProductApplications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.
References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)Formula:C27H46O2Color and Shape:NeatMolecular weight:402.65(E,E)-Farnesol 11,11,11,12,12,12-d6
CAS:Controlled ProductFormula:C15H20D6OColor and Shape:NeatMolecular weight:228.424-Epicerebrosterol
CAS:Controlled ProductFormula:C27H46O2Color and Shape:NeatMolecular weight:402.6517alpha-Estradiol
CAS:Controlled ProductImpurity Estradiol 17?-Hydroxy Impurity; Estradiol EP Impurity B; Ethinylestradiol EP Impurity L
Applications Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain(1,2). 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke(3).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
References 1. Lievertz, R. et al.: J. Obstet. Gynecol. 1987 May;156(5):1289-932. Kuhnz, W. et al.: Arzneimittelforschung. 1993 Sep;43(9):966-73.3. Toran-Allerand, C. et al.: Endocrinology. 2005 Sep;146(9):3843-50.Formula:C18H24O2Color and Shape:WhiteMolecular weight:272.381,2-Distearoyl-3-oleoyl-rac-glycerol
CAS:Applications 1,2-Distearoyl-3-oleoyl-rac-glycerol is used in the study of leptin resistance at the blood-brain barrier.
References Banks, W., et al.: Diabetes, 53, 1253 (2004);Formula:C57H108O6Color and Shape:NeatMolecular weight:889.46(-)-Norgestrel-d6
CAS:Controlled ProductApplications Labelled (-)-Norgestrel, an emergency contraceptive. Levonorgestrel is safe, tolerated and effective in emergency contraception in woman.
References Fotherby, K., et al.: J. Steroid Biochem., 19(1C), 817 (1983), Stanczyk, F. Z., et al.: Contraception, 42, 67 (1990), Bednarek, P., et al.: Drugs, 67, 2478 (2007),Formula:C21D6H22O2Color and Shape:NeatMolecular weight:318.48Trichloronate 10 µg/mL in Cyclohexane
CAS:Applications A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.
References Chyou, P., et al.: Age Ageing, 29, 69 (2000), Schatz, I., et al.: Lancet, 358, 351 (2001), Bjorkman, M., et al.: Eur. J. Endocrinol., 158, 749 (2008),Formula:C27H46OColor and Shape:White To Off-WhiteMolecular weight:386.65(+)-cis-Diltiazem-d3 HCl (acetoxy-d3)
CAS:Controlled ProductApplications (+)-cis-Diltiazem-d3 HCl (acetoxy-d3) (CAS# 1217860-13-3) is a useful isotopically labeled research compound.
Formula:C22D3H23N2O4S·ClHColor and Shape:NeatMolecular weight:454.0(25R)-26-Hydroxycholesterol
CAS:Controlled ProductApplications (25R)-26-Hydroxycholesterol is a desmosterol metabolite that is found in the brain. 26-Hydroxycholesterol has been used as a biomarker for carbon cycling in the northwestern Mediterranean Sea.
References Meljon, A., et. al.: J. Lipid Res., 53, 2469 (2012); Christodoulou, S., et. al.: Marine Chem., 113, 25 (2009)Formula:C27H46O2Color and Shape:NeatMolecular weight:402.652(S)-Equol
CAS:Controlled ProductApplications (S)-Equol and R-Equol are metabolites of the soy isoflavones Daidzein (D103500) and Genistein. Both have significant biological actions.
References Heinonen, S., et al.: Anal. Biochem., 274, 211 (1999), Setchell, K., et al.: J. Nutr., 132, 3577 (2002), Thigpen, J., et al.: Comp. Med., 53, 607 (2003), Yee, S., et al.: Food Chem. Toxicol., 46, 2713 (2008),Formula:C15H14O3Color and Shape:WhiteMolecular weight:242.2720(S)-Ginsenoside Rh1
CAS:Controlled ProductApplications 20(S)-Ginsenoside Rh1 is an anti-cancer agent found in the leaves of ginseng.
References Zheng, M. et al.: Biomed. Res., 26, 646 (2015);Formula:C36H62O9Color and Shape:NeatMolecular weight:638.87(+)-20-Hydroxyecdysone
CAS:Applications (+)-20-Hydroxyecdysone regulates gene transcription via a genomic pathway through a transcription complex that is formed.
References Liu, W. et al.: Endocrinol., 155, 1738 (2014); Wang, Q. et al.: Plant Physiol. Biochem., 84, 1 (2014);Formula:C27H44O7Color and Shape:White To Off-WhiteMolecular weight:480.63a-Terpinene (~90%)
CAS:Controlled ProductFormula:C10H16Purity:~90%Color and Shape:ColourlessMolecular weight:136.23sn-Glycero-3-phosphocholine-d9
CAS:Controlled ProductStability Hygroscopic
Applications sn-Glycero-3-phosphocholine-d9 is an isotope labelled analog of sn-Glycero-3-phosphocholine (G598700); a phospholipid and precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in the catabolic pathway of phosphatidylcholine and is used as an nootropic.
References Schmidt, G., et al.: J. Biol. Chem., 161, 523 (1945); Frattola, L., et al.: Curr. Ther. Res., 49, 683 (1991); Olson, D., et al.: Science, 270, 1967 (1995)Formula:C8H11D9NO6PColor and Shape:Colourless To Light YellowMolecular weight:266.285a-Cholesta-7,24-diene-3b-ol
CAS:Applications 5α-Cholesta-7,24-diene-3β-ol, is the derivative of Zymosterol (Z701520). It can also be used for identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology.
References Sato, Y., et al.: J. Lipid Res., 53, 567 (2012); Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934);Formula:C27H44OColor and Shape:Off-WhiteMolecular weight:384.64(2S)-2-Hydroxyglutaric Acid Disodium Salt
CAS:Controlled ProductApplications A potential inhibitor of glutamate carboxypeptidase.
References Wolcott, T.G., et al.: Biochem. Biophys. Res. Commun., 57, 709 (1974), Knowles, P.F., et al.: Eur. J. Biochem., 114, 139 (1981),Formula:C5H6O5·2NaColor and Shape:NeatMolecular weight:192.083β,5α,6β-Trihydroxycholestane-d7
CAS:Controlled ProductFormula:C27H41D7O3Color and Shape:NeatMolecular weight:427.711,2-Dipalmitoyl-sn-glycero-3-phosphocholine (Colfosceril Palmitate)
CAS:Controlled ProductStability Hygroscopic
Applications Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
References Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),Formula:C40H80NO8PColor and Shape:NeatMolecular weight:734.0414,15-Epoxyeicosatrienoic Acid
CAS:Controlled ProductApplications Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,N'-dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore.Also, it is derived from Arachidonic Acid >97% (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.
References Zhao, X., et al.: J. Am. Soc. Nephrol., 15, 1244 (2004); Fang, X., et al.: J. Biol. Chem., 276, 14867 (2001); Kurosawa, T., et al.: J. Cell. Physiol., 219, 606 (2009); Mazalli, M., et al.: J. Agric. Food Chem., 57, 5028 (2009);Formula:C20H32O3Color and Shape:NeatMolecular weight:320.466PazePC (>90%)
CAS:Controlled ProductFormula:C33H64NO10PPurity:>90%Color and Shape:NeatMolecular weight:665.8417-Desacetyl Norgestimate
CAS:Controlled ProductApplications A metabolite of Norgestimate. Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.
References Phillips, A., et al.: Steroids, 55, 373 (1990)Formula:C21H29NO2Color and Shape:White To BeigeMolecular weight:327.461-Palmitoyl-rac-glycerol
CAS:Applications 1-Palmitoyl-rac-glycerol is a biomarker of metabolic responses to hepatotoxicants and carcinogens.
References Broadhurst, D., et al.: Metabolomics, 2, 171 (2006), Shi, J., et al.: Nat. Biotechnol., 25, 930 (2007),Formula:C19H38O4Color and Shape:NeatMolecular weight:330.517β-Estradiol 3-O-Sulfate Sodium
CAS:Controlled ProductStability Hygroscopic
Applications 17β-Estradiol 3-O-Sulfate is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.
References Li, W.J., et al.: J. Pharmacol. Exp. Therp., 323, 236 (2007); Schneider, C., et al.: Steroids., 69, 245 (2004);Formula:C18H23O5S·NaColor and Shape:NeatMolecular weight:374.43Cholesterol 3-Sulfate Sodium Salt
CAS:Controlled ProductFormula:C27H45O4S·NaColor and Shape:White PowderMolecular weight:488.717-(3-Pyridinyl)-androsta-4,16-dien-3-one
CAS:Controlled ProductFormula:C24H29NOColor and Shape:NeatMolecular weight:347.492-Palmitoyl-rac-glycerol
CAS:Applications A biomarker of metabolic responses to hepatotoxicants and carcinogens.
References Broadhurst, D., et al.: Metabolomics, 2, 171 (2006), Shi, J., et al.: Nat. Biotechnol., 25, 930 (2007),Formula:C19H38O4Color and Shape:NeatMolecular weight:330.51-Arachidoyl-sn-glycero-3-phosphocholine
CAS:Controlled ProductApplications 1-Arachidoyl-sn-glycero-3-phosphocholine is a derivative of sn-Glycero-3-phosphocholine (G598700) and can be used as a biomarker in biological studies.
References Tang, C.,et al.: J. Chromatogr. B, 879, 2095 (2011)Formula:C28H58NO7PColor and Shape:NeatMolecular weight:551.73611Beta-Hydroxy Progesterone
CAS:Controlled ProductApplications 11beta-Hydroxyprogesterone (CAS# 600-57-7) is a useful research chemical compound.
Formula:C21H30O3Color and Shape:White To Off-WhiteMolecular weight:330.46POPE
CAS:Controlled ProductStability Light Sensitive, Moisture Sensitive
Applications POPE is a component of E. Coli bacteria cell membrane.
References Tu, Y., et al.: Nature Nanotechnology, 8, 594 (2013).Formula:C39H76NO8PColor and Shape:NeatMolecular weight:718.0(2S,3R,4E)-2-Amino-4-tetradecene-1,3-diol
CAS:Controlled ProductApplications Sphingosine base present in crayfish and drosophila, contributing to muscle degeneration
References Kita, K., et al.: Eur. J. Biochem., 268, 592 (2001), Fyrst, H., et al.: J. Lipid Res., 49, 597 (2008),Formula:C14H29NO2Color and Shape:NeatMolecular weight:243.3913-Oxyingenol Dodecanoate
CAS:Controlled ProductApplications 13-Oxyingenol Dodecanoate is a diterpene compound with antinematodal activity. Derivative of Ingenol (I655795), the analogue of Ingenol 3-Angelate (I655800), which has anti-tumor activity when used topically for the treatment of actinic keratosis.
References Shi, J. et al.: Z. Naturforsch. C: J. Biosci., 63, 59 (2008); Ogbourne, S.M., et al.: Cancer. Res., 64, 2833 (2004); Zayed, S.M., et al.: J. Cancer. Res. Clin. Oncol., 127, 40 (2001);Formula:C32H50O7Color and Shape:NeatMolecular weight:546.74Isoallolithocholic Acid
CAS:Controlled ProductApplications Isoallolithocholic Acid is used as a steroid compound as T regulatory lymphocyte modulators and uses for treatment of inflammatory or autoimmune disorders.
References Littman, D. R., et al.: PCT Int. Appl. 160pp. (2020)Formula:C24H40O3Color and Shape:White To Off-WhiteMolecular weight:376.58(R)-Propionyl Carnitine Chloride
CAS:Controlled ProductStability Hygroscopic
Applications L-Propionyl carnitine has been shown to improve the heart's mechanical recovery and other metabolic parameters after ischemia-reperfusion.
References Reznick, A.Z., et al.: Arch. Biochem Biophys., 296, 394 (1992),Formula:C10H20NO4·ClColor and Shape:NeatMolecular weight:253.72(-)-8-Prenylnaringenin
CAS:Applications (-)-8-Prenylnaringin is a prenylflavonoid, a class on non-steroidal phytoestrogen that mimicks and/or modulating endogenous estrogens via estrogen receptor binding.
References Miyamoto, M. et al.: Planta Med., 64, 516 (1998); Kim, H.J. et al.: Arch. Pharm. Res., 31, 1241 (2008); Zierau, O. et al.: Mol. Cell. Endocrinol., 294, 92 (2008);Formula:C20H20O5Color and Shape:NeatMolecular weight:340.371,3-Dioleoyl-2-palmitoylglycerol
CAS:Controlled ProductApplications A triglyceride for use in making human milk replacements.
References Nakaya, H., et al.: Biotechnology Techniques, 12, 881 (1998), Chen, M., et al.: J. Am. Oil Chemists’ Society, 91, 525 (2004),Formula:C55H102O6Color and Shape:Colourless To Off-WhiteMolecular weight:859.3912Beta-Hydroxyisocholic Acid
CAS:Stability Hygroscopic
Applications 12β-Hydroxyisocholic Acid is a bile acid.
References Batta, A.K., et. al.: J. Lipid Res., 32, 977 (1991)Formula:C24H40O5Color and Shape:Off White SolidMolecular weight:408.571,2-Dioleoyl-sn-glycero-3-phosphocholine
CAS:Controlled ProductStability Hygroscopic, Light Sensitive
Applications 1,2-Dioleoyl-sn-glycero-3-phosphocholine is used in the generation of micelles and liposomes.
References Høyrup, P., et al.: Biochim. Biophys. Acta, 1515, 133 (2001); Heberle, F., et al.: Cold Spring Harb Perspect Biol., 3, 1 (2011)Formula:C44H84NO8PColor and Shape:NeatMolecular weight:786.114beta-Hydroxy Cholesterol-d7
CAS:Controlled ProductApplications 4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),Formula:C27H39D7O2Color and Shape:Off WhiteMolecular weight:409.712-Hydroxylauric Acid
CAS:Controlled ProductApplications 12-Hydroxylauric Acid is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum.
References Kubienova, L., et. al.: Biochimie, 95, 889 (2013)Formula:C12H24O3Color and Shape:NeatMolecular weight:216.32Stigmasterol
CAS:Applications Plant sterol, used as a precursor in the synthesis of progesterone.
References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009), Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009), Huang, C., et al.: Plant Physiol., 150, 1192 (2009),Formula:C29H48OColor and Shape:White To Off-WhiteMolecular weight:412.69Cholesteryl Palmitate
CAS:Controlled ProductFormula:C43H76O2Color and Shape:NeatMolecular weight:625.06n-Dodecyl beta-D-Maltoside
CAS:Controlled ProductApplications n-Dodecyl β-D-Maltoside is a widely used detergent to solubilize membrane proteins.
References Hildebrandt, E., et. al.: BBA-Biomembranes, 1838, 2825 (2014)Formula:C24H46O11Color and Shape:NeatMolecular weight:510.62

