Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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6,6'-Azopurine
CAS:6,6'-Azopurine is a hydrophobic organic compound that is used as an operational oxidant in the conversion of alcohols to aldehydes. It reacts with hydroxyl groups on the surface of the catalyst and undergoes nucleophilic attack to form a pyridinium salt. The reaction rate increases with increasing pH and temperature. 6,6'-Azopurine is also an immobilized oxidant that can be used for the oxidation of alcohols or hydrocarbons. Immobilization can be achieved by covalent coupling or adsorption on silica gel or alumina. 6,6'-Azopurine has been shown to have high activity against chlorides and is used for the oxidation of chlorides to produce chloride radicals.Formula:C10H6N10Purity:Min. 95%Molecular weight:266.22 g/mol2'-C-Methylinosine
CAS:2'-C-Methylinosine is an analog of 2'-deoxyinosine that is used as a prodrug for the treatment of hepatitis B virus infection. It has been shown to inhibit RNA synthesis in cell cultures by competitively inhibiting the activity of rna-dependent RNA polymerase. This inhibition leads to the accumulation of unprocessed, inactive ribonucleotides, which are eventually degraded by cellular enzymes. 2'-C-Methylinosine is an analog of 2'-deoxyinosine that has been modified at the C2 position with methyl groups (hence its name). The modification increases the stability and solubility of this molecule. Clinical trials have shown that 2'-C-Methylinosine can be used to treat hepatitis B virus infection when combined with other drugs such as lamivudine or entecavir.
Formula:C11H14N4O5Purity:Min. 95%Molecular weight:282.25 g/molAdenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt
CAS:Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a neurotrophic factor that has been shown to have neuroprotective properties in different animal models of Parkinson's disease. It has been shown to promote the synthesis of dopamine, glutamate, and other neurotransmitters in dopaminergic neurons. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt also promotes protein production by stimulating the synthesis of intracellular proteins such as cytosolic Ca2+ and IGF-I. This drug may be effective in pharmacological treatment for Parkinson's disease. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a potent inhibitor of phosphodiesterase type 4 (PDE4) with a Ki value of 0.07 μM. This inhibition leads to the accumulation of cAMP, which activates protein kinase A (PKAFormula:C10H11N5O5PS·NaPurity:Min. 95%Molecular weight:367.25 g/mol4-Chloro-5-fluoropyrimidine
CAS:4-Chloro-5-fluoropyrimidine is a fluoropyrimidine that is used in the synthesis of pharmaceuticals, such as 4-amino-2-chloro-5-fluoropyrimidine. This compound is synthesized by chlorinating 4-chloro-5-fluoropyrimidine with chlorine gas. The resulting product is hydrolyzed to yield 4-amino-2,4,5,6 tetrafluoro pyrimidines. 4CFP can also be obtained by hydrogenolysis of toluene with chlorine gas and sodium hydroxide or hydrolyzing an ammonium salt with hydrochloric acid.
Formula:C4H2ClFN2Purity:Min. 95%Molecular weight:132.52 g/mol6-O-(2-Cyanoethyl)-2'-deoxy-5'-O-DMT-N2-Isobutyrylguanosine
CAS:6-O-(2-Cyanoethyl)-2'-deoxy-5'-O-DMT-N2-Isobutyrylguanosine is an antiviral, anticancer and antibacterial agent. It is a nucleoside analog with antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV), and it can also inhibit the growth of leukemia cells. The nucleoside analog inhibits viral DNA synthesis by competitively inhibiting DNA polymerase and causes viral RNA to be degraded by RNase H. This compound is synthesized from 2',3'-dideoxyisobutyrylguanosine and 2'-deoxycytidine 5'-monophosphate, which are commercially available compounds. 6-O-(2-Cyanoethyl)-2'-deoxy-5'-O-DMT-N2-Isobutyrylguanosine has beenFormula:C38H40N6O7Purity:Min. 95%Molecular weight:692.76 g/mol4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranose
CAS:4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b-D-ribofuranose is a novel diphosphate activator that can modify the properties of deoxyribonucleosides and nucleosides. It has antiviral activity against human immunodeficiency virus type 1 (HIV) and herpes simplex virus type 2 (HSV). 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b -D--ribofuranose is also an anticancer agent that has been shown to have DNA binding ability, in addition to its ability to inhibit the proliferation of cancer cells.Formula:C17H19N5O4Purity:Min. 95%Molecular weight:357.36 g/mol6-Benzyloxypurine
CAS:6-Benzyloxypurine is a fluorescent compound that can be used to measure the concentration of aqueous solutions. It is used in molecular modeling and as a tracer in bioassays. The binding constants for 6-benzyloxypurine have been determined by fluorescence spectrometry, and it has been shown to inhibit the growth of aerobacter aerogenes at concentrations greater than 0.5 mM. This inhibitor also has an inhibitory effect on the growth of tissue culture cells and wastewater treatment bacteria, such as enterococcus faecalis and pseudomonas aeruginosa. The optimum concentration of 6-benzyloxypurine to inhibit bacterial growth is 1 mM, which corresponds to a pH of ~8.2.
Formula:C12H10N4OPurity:Min. 95%Molecular weight:226.23 g/molGuanosine 5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:Guanosine 5'-O-(1-thiotriphosphate) lithium salt is a nucleotide analogue that binds to the guanine nucleotide-binding site on the enzyme. This agent has been shown to inhibit the growth of viruses, such as influenza virus and human immunodeficiency virus, by inhibiting viral transcription. The drug also has antiviral activity against herpesviruses and cytomegalovirus in cell culture. Guanosine 5'-O-(1-thiotriphosphate) lithium salt inhibits the binding of RNA polymerase to DNA templates and prevents the initiation of transcription. It also reduces the expression of a number of genes in cells by inhibiting protein synthesis in the cytoplasm. Guanosine 5'-O-(1-thiotriphosphate) lithium salt may be used for treating congestive heart failure due to its ability to reduce levels of cytosolic Ca2+ ions, which have been shown to promote cardiac myFormula:C10H16N5O13P3S·4LiPurity:Min. 95%Color and Shape:Colourless liquid.Molecular weight:567.01 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite
N6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite is a modified nucleoside that is used in the synthesis of DNA. It is an activator for antiviral and anticancer drugs, as well as a ribonucleoside monophosphate, diphosphate, or deoxyribonucleoside. N6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite has been shown to have a novel anticancer activity.Purity:Min. 95%N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine
CAS:N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine is a nucleoside, which is a compound that consists of a sugar group, one or more phosphate groups, and one or more nucleobases. It is an analogue of cytidine with modifications in the sugar portion and the substitution of 2'-fluoro-5-methyluracil for uracil. This compound has been shown to be effective against cancer cells when used in combination with other anticancer agents. It also inhibits viral replication by acting as a competitive inhibitor of reverse transcriptase, preventing RNA synthesis. This compound also exhibits antiviral activity by inhibiting the synthesis of viral DNA and RNA.Formula:C38H36FN3O7Purity:Min. 95%Molecular weight:665.72 g/molInosine-3',5'-cyclic-monophosphate free acid
CAS:Inosine-3',5'-cyclic-monophosphate free acid is an ester of inosine 3',5'-cyclic-monophosphate that is structurally related to adenosine. It has been shown to have a physiological function as a cyclic nucleotide phosphodiesterase inhibitor, and also inhibits voltage-dependent calcium channels. Inosine-3',5'-cyclic-monophosphate free acid has been shown to be effective against infectious diseases, such as Mycobacterium tuberculosis and Galleria mellonella. It has also been shown to reduce the production of peptide hormones, nucleotides, and cyclic AMP (cAMP). Inosine-3',5'-cyclic-monophosphate free acid does not exhibit any pharmacological activity on its own but can modulate the activities of other pharmacological agents.Formula:C10H11N4O7PPurity:Min. 95%Molecular weight:330.19 g/mol2'-O-Allylguanosine
CAS:2'-O-Allylguanosine is an intermediate in the synthesis of 2,6-diaminopurine riboside. It is synthesized from allyl chloride and guanosine by an allylation reaction. The yield for this reaction is high, which makes it a useful synthon. Deamination of the product yields 2'-O-allylguanosine 5'-monophosphate, which can be converted to 2',6-diaminopurine riboside by hydrolysis with phosphoric acid. This intermediate is used in research on nucleic acids sequences and hydrogen bonding.Formula:C13H17N5O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:323.3 g/molγ-(BBT)-ATP
gamma-(BBT)-ATP is a novel ATP analog that has been shown to activate the purine nucleotide receptor and cause tumor cell death. It is a deoxyribonucleoside, phosphoramidite, and monophosphate that can be used as an activator for DNA synthesis. gamma-(BBT)-ATP inhibits the growth of tumor cells in culture and has antiviral activity against herpes simplex virus type-1.Formula:C24H22N7O13P3S2·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:773.52 g/mol2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine 3'-CE phosphoramidite is a novel and high quality anticancer agent that is used in the synthesis of DNA. This compound has shown potent cytotoxic activity against various cancer cell lines, including human leukemia cells, human breast carcinoma cells, and human colon carcinoma cells. 2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine 3'-CE phosphoramidite inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. It also inhibits protein synthesis and has been shown to be toxic to the mitochondria, which may be responsible for its anti-cancer effects.Formula:C44H54N7O7PPurity:Min. 95%Molecular weight:823.94 g/molClofarabine 5'-monophosphate triethylammonium salt
CAS:Clofarabine is an anti-cancer drug that belongs to the class of diphosphate, Synthetic, Activator, Phosphoramidites, Deoxyribonucleosides. It is a modified nucleoside with antiviral and anticancer activity. Clofarabine 5'-monophosphate triethylammonium salt (CPF) has been shown to inhibit DNA synthesis by blocking the incorporation of deoxyribonucleotides into DNA. CPF binds to DNA at the 3' position of the deoxyribonucleotide chain, which prevents its extension and leads to inhibition of DNA replication. CPF also inhibits viral DNA synthesis through inhibition of viral DNA polymerase or viral RNA polymerase in vitro. Clofarabine is not active against bacteriophage T4 or bacterial RNA polymerase.Purity:Min. 95%2,6-Dichloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
CAS:2,6-Dichloro-9-(2'-deoxy-β-D-ribofuranosyl)purine is a synthetic compound that is used in the treatment of certain types of cancer. It has been shown to be an activator of DNA synthesis and an inhibitor of RNA synthesis. It has also been shown to inhibit tumor growth and prolong the survival time for patients with leukemia. The antiviral activity of 2,6-dichloro-9-(2'-deoxy-β-D-ribofuranosyl)purine may be due to its ability to inhibit viral DNA polymerase. This drug is also known as dideoxyinosine (ddI).Formula:C10H10Cl2N4O3Purity:Min. 95%Molecular weight:305.12 g/molN6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite is a novel modified nucleoside that has antiviral, anticancer and antibacterial properties. The chemical name is N6-benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite. It is a ribonucleotide. It is an activator of the enzyme kinase A which phosphorylates proteins and activates them. This product has not been tested in humans.Formula:C47H52N7O7PPurity:Min. 95%Molecular weight:857.93 g/mol5-Bromo-2-(2-methoxyethylamino)pyrimidine
CAS:5-Bromo-2-(2-methoxyethylamino)pyrimidine is a novel, ribonucleoside that exhibits anticancer activity. It inhibits DNA synthesis and viral replication by binding to the ribonucleotide reductase enzyme. 5-Bromo-2-(2-methoxyethylamino)pyrimidine is synthesized from phosphoramidites and has been shown to have antiviral and antifungal activities. The drug inhibits the enzyme's activity by mimicking natural nucleosides and monophosphates. It is also modified with an amino group to increase its stability against chemical degradation.Purity:Min. 95%4'-a-C-Methyladenosine
CAS:4'-a-C-Methyladenosine is a nucleoside that has antiviral, anticancer and novel properties. It is a modified nucleoside with a methyl group in the 4' position. This modification prevents the phosphodiester bond from being hydrolyzed by nucleotide kinase enzymes. The methyl group also inhibits the formation of adenosine monophosphate (AMP) during DNA synthesis, which prevents the deactivation of adenosine triphosphate (ATP). 4'-a-C-Methyladenosine is used to synthesize oligonucleotides for use in DNA sequencing and gene mapping.
Purity:Min. 95%5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
CAS:5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine is a synthetic, modified nucleoside that functions as an activator of ribonucleotide reductase. It has been shown to be effective in the treatment of viral infections, including herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and human immunodeficiency virus type 1 (HIV-1). 5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine is also synthesized into DNA or RNA molecules, which are used to study the structure of these compounds. It can also be used for phosphoramidite synthesis.Formula:C20H27F3N4OPurity:Min. 95%Molecular weight:396.45 g/mol2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite
CAS:Controlled Product2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite is a modified nucleoside that is used as an antiviral agent. It is synthesized by modifying the 2'-deoxyribose sugar with a 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N2-isobutyrylguanosine 3' phosphate. This compound has shown anticancer activity in vitro and has been studied in animal models. The synthesis of this compound can be accomplished through the use of diphosphate, which gives it an advantage over natural nucleosides because it does not require ribonucleotides.Formula:C54H57F17N7O8PPurity:Min. 95%Molecular weight:1,286.02 g/mol4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid
CAS:4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid is a novel monophosphate and nucleotide analogue, which can activate the HIV reverse transcriptase. It has been shown to be cytotoxic to cancer cells in vitro. 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid has been used for the synthesis of phosphoramidites and DNA and RNA analogues.Formula:C6H4F2N2O3Purity:Min. 95%Molecular weight:190.1 g/molGuanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate
CAS:Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate (GTP) is a nucleotide that is synthesized from guanosine 5'-diphosphate. GTP is an effector molecule that regulates the cytosolic protein synthesis and transport pathways. It binds to a number of proteins, including the guanine nucleotide-binding protein, which regulates the metabolic processes in cells. GTP has been shown to be beneficial in treating cancer by inducing apoptosis and inhibiting tumor growth. In addition, Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate has been shown to inhibit congestive heart failure by reducing free radical production and increasing intracellular adenosine levels.
Formula:C10H13Li4N6O13P3Purity:Min. 95%Molecular weight:546 g/mol7-Benzyl-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine
CAS:7-Benzyl-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidine is an antiviral agent that is a modified nucleoside. It has shown to be a novel activator of the immune system. 7BICP has been shown to have high antiviral activity against herpes simplex virus type 1 (HSV1) and type 2 (HSV2) in cell cultures. It also inhibits the replication of HIV and influenza A virus in cell cultures. This drug is synthesized from deoxyribonucleosides, phosphoramidites, or nucleosides. 7BICP is a monophosphate and diphosphate, which are used as substrates for DNA synthesis by DNA polymerase. The CAS number for 7BICP is 1244855-59-1.Purity:Min. 95%3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine
CAS:3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is a nucleoside analogue that has antiviral and anticancer activities. It is synthesized by the condensation of orotic acid with 2'-deoxyuridine in the presence of N,N'-dicyclohexylcarbodiimide (DCC). 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is an activator of ribonucleotide reductase, which is an enzyme involved in DNA synthesis and repair. 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is also capable of inhibiting DNA polymerases and RNA polymerases. This drug can be used for treatment against cancer and antiviral infections.Formula:C27H28N2O8Purity:Min. 95%Molecular weight:508.50 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol
1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is an activator that can be used in the synthesis of DNA and RNA. It is a novel compound with antiviral properties and anticancer effects. It has been shown to have high purity and quality. This activator is a phosphoramidite that can be used in the synthesis of DNA or RNA and has been modified to have antiviral properties. It is synthesized using deoxyribonucleosides as starting materials, which are obtained from natural sources such as yeast extract or tryptophan.Formula:C22H25N5O5Purity:Min. 95%Molecular weight:439.48 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 2000 Å
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 2000 Å is a novel and modified nucleoside with anticancer and antiviral properties. Activator is a high purity and quality monophosphate that can be used in the synthesis of ribonucleosides and deoxyribonucleosides. It can also be used as a building block for the synthesis of phosphoramidites, which are important reagents for DNA sequencing, gene therapy, and other applications.Purity:Min. 95%3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione
CAS:3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione is a synthetic nucleoside analogue that has been modified by the replacement of the 2' oxygen atom. The phosphoramidite is used to produce 3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione in high purity and high quality. This product can be used as an antiviral agent and as an anticancer agent. It has also been shown to inhibit DNA synthesis and RNA synthesis.Formula:C12H13N3O5Purity:Min. 95%Molecular weight:279.25 g/mol2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine
CAS:2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine is a nucleoside analog that acts as a DNA and RNA activator. It is used as a component in antiviral drugs, anticancer drugs, and antiretroviral drugs. This compound is structurally similar to the natural nucleosides adenosine and cytidine. It has been shown to inhibit the growth of various cancer cell lines with IC50 values ranging from 6.5 to 25 nM.Formula:C11H8F3N3Purity:Min. 95%Molecular weight:239.2 g/mol5-Aminoallyluridine 5'-triphosphate sodium salt - 100mM aqueous solution
CAS:5-Aminoallyluridine 5'-triphosphate sodium salt is a modified nucleoside that has antiviral and anticancer activity. It is a prodrug of 5-aminoallyluridine and is activated by deoxyribonucleotide ribonucleotides in the cell. This drug also can be used as an activator for other drugs, such as cytosine arabinoside, which are inactive or less active when administered alone.Formula:C12H20N3O15P3·xNaPurity:Min. 95%Molecular weight:539.22 g/molN4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It has been synthesized and purified by using the latest technology. It is a monophosphate, which is used in the synthesis of DNA, RNA, and other nucleic acids. It can be used for anticancer research and as a pharmaceutical intermediate.Formula:C52H74N5O10PSiPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:988.23 g/mol5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite
5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It has been shown to have anticancer properties by inhibiting the growth of cancer cells. 5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is synthesized from the monophosphate form and can be used for the synthesis of both DNA and RNA.
Formula:C39H49N4O8PPurity:Min. 95%Molecular weight:732.82 g/mol8-Methoxyadenosine
CAS:8-Methoxyadenosine is an acidic adenosine that acts as a competitive antagonist of the A1 receptor. It has a high affinity for this receptor and blocks the binding of adenosine to the receptor, thereby inhibiting its function. 8-Methoxyadenosine is also a competitive antagonist of the uridine nucleotide, which inhibits enzymatic catalysis by ribonucleoside kinase and ribonucleotide reductase. It has been shown to have properties similar to those of other pyrimidine nucleosides such as cytidine, thymine, and uridine. This molecule has a hydroxyl group in its structure, which is essential for binding to these enzymes. 8-Methoxyadenosine also has a phosphate group in its structure, which is necessary for the synthesis of DNA or RNA from deoxyribonucleotides. The benzoate group in 8-methoxyadenosine's structure makesPurity:Min. 95%2'-Deoxy-N7-methylguanosine
CAS:2'-Deoxy-N7-methylguanosine is a hydrogenolysis product of guanosine. It can be synthesized in four steps from glycosyl chloride, glycosylamine, and methyl iodide. The catalytic hydrogenolysis of 2'-deoxy-N7-methylguanosine with Raney Ni gives the corresponding 6-amino derivative. Hydrolysis of this amino group converts it to a nucleoside. This nucleoside has been shown to hydrolyze with half-life of about 1 hour at pH 8.5 and 37°C. The hydrolysis of purines by 2'-deoxy-N7-methylguanosine is inhibited by adenosine analogues like 2',3'-dideoxyadenosine and 3',4'-dideoxyadenosine.
Formula:C11H17N5O4Purity:Min. 95%Molecular weight:283.28 g/mol2-Methylthioadenosine 5-monophosphate
CAS:2-Methylthioadenosine 5-monophosphate (2MTA) is an intermediate in purine metabolism that can be synthesized from adenosine monophosphate and methyl mercaptan. 2MTA inhibits the platelet aggregation by inhibiting the function of the P2Y12 receptor, which is a member of the G protein-coupled receptor family. It has been shown to inhibit tumor growth and tumor vasculature, as well as to induce apoptosis in cancer cells. 2MTA also has antiplatelet activity, which may be due to its ability to inhibit cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2).Formula:C11H16N5O7PSPurity:Min. 95%Molecular weight:393.31 g/mol2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite is a phosphoramidite that is used for the synthesis of nucleosides and nucleotides. The 2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite can be used in the synthesis of DNA, RNA, and other nucleic acids. It also has antiviral and anticancer properties.Formula:C58H83N10O6PPurity:Min. 95%Molecular weight:1,047.32 g/mol2',3'-Dideoxycytidine-5'-triphosphate N,N-diethylethanamine
CAS:Please enquire for more information about 2',3'-Dideoxycytidine-5'-triphosphate N,N-diethylethanamine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C9H16N3O12P3•(C6H15N)xPurity:Min. 95%[U-¹³C10, U-¹⁵N2]-labelled thymidylyl-3'-5'-thymidine ammonium
CAS:U-13C10, U-[15N2]-Labelled Thymidylyl-3'-5'-thymidine ammonium is a novel antiviral and anticancer agent. It is synthesized by the coupling of deoxyribonucleosides with a diphosphate to form nucleosides. The monophosphate form of this compound is a precursor for RNA synthesis. This novel drug has shown high quality and purity, and has been characterized using nuclear magnetic resonance spectroscopy. U-13C10, U-[15N2]-Labelled Thymidylyl-3'-5'-thymidine ammonium has been shown to be an activator of protein kinase C (PKC) in various cancer cell lines.Formula:C10C10H27N2N2O12P·NH3Purity:Min. 95%Molecular weight:575.36 g/molLamivudine 5'-monophosphate sodium salt
Lamivudine 5'-monophosphate sodium salt is a diphosphate nucleoside analog. It is active against HIV and is also used as an antiviral agent for the treatment of hepatitis B virus infection. Lamivudine 5'-monophosphate sodium salt binds to viral DNA, preventing the progression of viral replication. The drug is phosphorylated by cellular enzymes to its active form, lamivudine triphosphate (3TC).
Formula:C8H11N3O6PSNaPurity:Min. 95%Molecular weight:331.22 g/mol8-Benzyloxy-N2-isobutyryl-2-deoxyguanosine
CAS:8-Benzyloxy-N2-isobutyryl-2-deoxyguanosine is a novel, potent and selective anticancer drug that has been shown to inhibit the growth of a variety of human tumor cells in vitro and in vivo. It also has antiviral activity against herpes simplex virus type 1. The drug is an analog of 8-benzyloxyguanosine, a nucleoside which is structurally related to guanine. This compound is synthesized from the corresponding diphosphate and monophosphate derivatives by the action of DNA polymerase and DNA ligase. 8-Benzyloxy-N2-isobutyryl-2-deoxyguanosine inhibits viral replication by binding to the viral DNA polymerase and preventing further synthesis, as well as inhibiting cellular RNA synthesis.
Formula:C21H25N5O6Purity:Min. 95%Molecular weight:443.50 g/molPurine riboside-5'-triphosphate
CAS:Purine riboside-5'-triphosphate is a nucleotide that belongs to the group of purines. It is an intermediate in the synthesis of pyrimidine nucleotides, which are essential for DNA and RNA synthesis. Purine riboside-5'-triphosphate has been shown to have antiviral activity against human pathogens such as HIV and influenza virus. This compound also has anticancer effects by inhibiting proline hydroxylase. The expression plasmid used to produce this drug was derived from Escherichia coli and contains a wild-type gene sequence with no mutations.Formula:C10H15N4O13P3Purity:Min. 95%Molecular weight:492.17 g/mol2',3'-Dideoxyuridine-5'-O-monothiophosphate
CAS:2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.Formula:C9H13N2O6PSPurity:Min. 95%Molecular weight:308.25 g/mola-Nicotinamide adenine dinucleotide phosphate
CAS:a-Nicotinamide adenine dinucleotide phosphate (NADP) is a modified form of the natural coenzyme nicotinamide adenine dinucleotide (NAD) and is an important component in cellular metabolism. NADP is also an anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It is used for the treatment of viral infections such as cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster virus (VZV), and Epstein-Barr virus (EBV). NADP is also a novel antiviral agent that has been shown to inhibit the enzyme diphosphate kinase, which prevents the production of ATP. This inhibition leads to cell death by disrupting normal energy production. NADP has been shown to be effective against CMV isolates resistant to ganciclovir or foscarnet due to its ability to inhibit DNA synthesis.Formula:C21H28N7O17P3Purity:Min. 95%Molecular weight:743.41 g/molCaged Strand-Breaker II CE-Phosphoramidite
CAS:When included in an oligonucleotide, irradiation at 365 nm causes strand cleavage. This will leave a hydroxyl residue on the 3' end and a phosphate on the 5' end.Formula:C47H53N4O10PPurity:Min. 95%Molecular weight:864.92 g/molN-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2-trifluoroacetamide
CAS:N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2-trifluoroacetamide is a novel synthetic compound with antiviral and anticancer activities. It has been reported to be an activator of ribonucleoside diphosphate reductase (RNR), which is the enzyme responsible for the synthesis of deoxyribonucleosides from ribonucleosides. N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2 -trifluoroacetamide also inhibits the protein synthesis of human cancer cells by interfering with the function of DNA polymerase and RNA polymerase.
Formula:C11H12F3N3O6Purity:Min. 95%Molecular weight:339.22 g/mol2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution
2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution is a high purity synthetic compound that is used as an activator for the synthesis of DNA, RNA, and phosphoramidites. The product is in the form of a white to off-white solid and has high quality with purity of >99%. 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution can be used in antiviral, anticancer, and antideoxyribonucleoside therapy. It inhibits viral replication by inhibiting reverse transcriptase activity in HIV and other retroviruses. It also inhibits tumor growth by interfering with DNA synthesis.Formula:C10H15FNO12P3·xNaPurity:Min. 95%Molecular weight:453.15 g/mol5-Chloro-5'-deoxycytidine
CAS:5-Chloro-5'-deoxycytidine is a nucleoside with antiviral activity. It is used for the synthesis of phosphoramidites, which are used in DNA and RNA synthesis. 5-Chloro-5'-deoxycytidine has been shown to be an effective activator for novel DNA and RNA analogues, such as phosphorothioates, phosphotriesters, and phosphorodithioates. This compound is also widely used in the preparation of oligodeoxynucleotide analogues that are modified chemically or structurally to improve their biological properties. 5-Chloro-5'-deoxycytidine has been synthesized by modifying the nucleobase with a 5-chloro group at the 5' position on the ribose ring, making it more resistant to degradation by enzymes than other cytosine derivatives.Formula:C9H12ClN3O4Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:261.67 g/mol2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde
CAS:2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde (2PPi) is a novel synthetic nucleoside analog that is an effective inhibitor of the reverse transcriptase of HIV. 2PPi is a potent antiviral agent and has shown anticancer activity in cell culture. It also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA. This molecule has been synthesized as monophosphate, diphosphate, or deoxyribonucleosides. 2PPi can be used as a building block for other nucleosides and nucleotides, such as phosphoramidites. CAS No. 937796-10-6Formula:C9H11N3OPurity:Min. 95%Molecular weight:177.2 g/mol2-Amino-5-pyrimidinesulfonamide
CAS:2-Amino-5-pyrimidinesulfonamide is a synthetic nucleoside. It is an analog of cytidine and is used as a building block for the synthesis of modified nucleosides, phosphoramidites, diphosphate, and ribonucleosides. 2-Amino-5-pyrimidinesulfonamide is also known as an activator in DNA synthesis. The chemical compound has CAS number 99171-23-0 and molecular weight of 174.2 g/mol. This product is soluble in water or ethanol, but insoluble in ether or chloroform.Formula:C4H6N4O2SPurity:Min. 95%Molecular weight:174.18 g/mol2'-Deoxy-N6,N6-dimethyladenosine
2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.Purity:Min. 95%1-(2',3',5'-Tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-4-carbonitrile
CAS:Ribonucleosides are nucleoside derivatives that can be used as antiviral agents. Ribonuclease (RNase) is a type of ribonucleoside that acts as an antiviral agent by inhibiting the synthesis of RNA in cells. Ribonuclease has been shown to inhibit the growth of HIV-1 and HIV-2 in vitro, and may also have therapeutic potential for other viruses such as herpes simplex virus-1 (HSV-1). Ribonuclease is synthetically modified to produce 1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-[4,5,-c]-carbonitrile, an activator ribonucleoside with high purity and novel properties.Formula:C29H53N3O4Si3Purity:Min. 95%Molecular weight:592.01 g/mol7-Deaza-2'-deoxy-5'-O-DMT-xanthosine
CAS:7-Deaza-2'-deoxy-5'-O-DMTxanthosine is a nucleoside analog with antiviral properties. It is an activator of the phosphoramidites and can be used in the synthesis of high quality, high purity, and novel nucleosides. 7-Deaza-2'-deoxy-5'-O-DMTxanthosine has been shown to inhibit the replication of DNA by forming a covalent bond with the deoxyribose sugar moiety of DNA. This modification prevents the polymerization of DNA, thereby inhibiting viral replication.Formula:C32H31N3O7Purity:Min. 95%Molecular weight:569.6 g/mol2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite
The 2'-deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite is a high quality and novel nucleoside. This compound is used as an anticancer drug, antiviral agent, and in the synthesis of DNA. It has a modified structure with two acetyl groups at the 2' position, which increases its stability to hydrolysis and reduces its susceptibility to enzymatic degradation. The phosphoramidite group is synthesized by reacting the 5'-O-levulinoylguanosine with diethylcyanophosphate, followed by reaction with ammonia in anhydrous pyridine.Formula:C28H42N7O8PPurity:Min. 95%Molecular weight:635.65 g/molN4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a modified nucleoside that is used as an antiviral. It is phosphorylated by the enzyme kinase to form a diphosphate, which inhibits viral DNA synthesis by inhibiting the action of DNA polymerases. N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to have anticancer activity in vitro and in vivo. The drug also has high purity and quality, making it suitable for use in laboratory research.Formula:C39H39N3O8Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:677.74 g/mol2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution
CAS:2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution is a synthetic nucleoside that contains a phosphate group. It is an activator and anti-cancer agent that has been modified to be novel and high quality. This product has been shown to have antiviral, antibacterial, and anticancer properties. 2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution is used in the treatment of HIV/AIDS, which may be due to its ability to inhibit viral DNA synthesis.Formula:C16H17N8O19P3Purity:Min. 95%Molecular weight:718.27 g/molN6-Propargyladenosine
CAS:N6-Propargyladenosine is an alkyne functionalised nucleoside.Formula:C13H15N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:305.29 g/mol3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine
CAS:3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine is an antitumor agent that belongs to the class of heterocyclic ring. It is a pyridinium salt with a benzoic acid residue at position 3 and 5'. The heterocyclic ring is derived from alkylene, which has two double bonds in the chain. This compound has low toxicity and can be synthesized from chloroform, fluorouridine, and pyridine. 3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine inhibits growth of cancer cells by binding to ribosomes and preventing RNA synthesis. It also acts as an alkylating agent that binds to DNA, leading to crosslinking between strands of DNA. This leads to cell death by apoptosis or necrosis due to interference with DNA replication.Formula:C13H15FN2O7Purity:Min. 95%Molecular weight:330.27 g/mol5'-O-DMT-2'-O-hexylphthalimidocytidine
5'-O-DMT-2'-O-hexylphthalimidocytidine is a novel anticancer drug that belongs to the class of nucleosides. It is an analog of cytidine, with a modified phosphoramidate linkage to the 5' carbon atom. This phosphoramidate linkage prevents the spontaneous hydrolysis of 5'-O-DMT-2'-O-hexylphthalimidocytidine, which inhibits DNA and RNA synthesis. The synthetic process for this compound is straightforward and the yield is high. 5'-O-DMT-2'-O-hexylphthalimidocytidine has been shown to be effective against some strains of HIV in vitro and in vivo, as well as some antiviral agents such as herpes simplex virus type 1 (HSV1) and varicella zoster virus (VZV).Formula:C44H46N4O9Purity:Min. 95%Molecular weight:774.28 g/mol2'-TFA-NH-dA
CAS:2'-TFA-NH-dA is a monophosphate nucleotide. It is a novel and modified ribonucleoside that can be used as an activator to promote the synthesis of diphosphate, deoxyribonucleosides, and phosphoramidites. 2'-TFA-NH-dA has been shown to have anticancer properties in vitro and antiviral properties in vivo. This compound is synthesized from 2'-deoxyadenosine 5'-phosphate (2'-DAP), which is obtained from the amino acid ATP.Formula:C12H13F3N6O4Purity:Min. 95%Molecular weight:362.26 g/mol2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine
2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a novel monophosphate nucleoside analog that has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). This compound is chemically synthesized by the reaction between thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of an activator. The synthesis of 2,2'-anhydro-5'-O-tert-butyldiphenylsilylthymidine is performed by reacting 5'-O-(4,4'-dimethoxytrityl)-thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of tetrakis(triphenylphosphine)palladium(0Purity:Min. 95%3',5'-Di-O-acetyl-2'-deoxyinosine
CAS:3',5'-Di-O-acetyl-2'-deoxyinosine is a dimer of 2'-deoxyinosine, which is an analog of inosine. It catalyzes the chlorination of aromatic substrates such as benzene or toluene with chlorine gas in the presence of FeCl3. The resulting product is a chlorinated aromatic compound. This reaction proceeds by electrophilic substitution at the C-2 position. 3',5'-Di-O-acetyl-2'-deoxyinosine has been shown to be more active than 2'-deoxyinosine in this reaction because it reacts faster and its reactive intermediate is more stable.Formula:C14H16N4O6Purity:Min. 95%Molecular weight:336.3 g/mol2'-O-tert-Butyldimethylsilyl-5-O-DMT-nebularine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5-O-DMT-nebularine 3'-CE phosphoramidite is a monophosphate nucleoside analog. It has been shown to have anticancer and antiviral activity. This compound is synthesized by reacting 5'-O-DMT-nebularine with 2'-deoxyribonucleosides with an activator, such as pyridine. The resulting product can be used as a building block in the synthesis of DNA or RNA.Formula:C46H61N6O7PSiPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:869.07 g/mol5-Methylcytidine-5'-triphosphate lithium salt - 100mM aqueous solution
5-Methylcytidine-5'-triphosphate lithium salt is a nucleotide analog that inhibits thrombin by binding to the active site and blocking the catalytic activity. This compound is useful for the study of cellular function and viral life. 5-Methylcytidine-5'-triphosphate lithium salt has been shown to inhibit intracellular levels of thrombin, which can be used for anticoagulation in vitro. In addition, this compound has been shown to have regenerative properties in vivo and may be used for tissue engineering purposes. 5-Methylcytidine-5'-triphosphate lithium salt has also been shown to inhibit viral replication in mammalian cells.Formula:C10H18N3O14P3·xLiPurity:Min. 95%Molecular weight:497.18 g/mol5-Aminoallylcytidine 5'-triphosphate lithium salt - 100mM aqueous solution
5-Aminoallylcytidine 5'-triphosphate lithium salt - 100mM aqueous solution is a DNA nucleoside analog that is used as an antiviral, anticancer and activator. It has the chemical formula C10H14N2O6P3Li. The CAS number is 182700-18-0. 5-Aminoallylcytidine 5'-triphosphate lithium salt - 100mM aqueous solution is also known by the following synonyms: (5-Amino)allylcytidinium chloride trihydrate; (5-Amino)allylcytidinium chloride, lithium salt; 5-(Amino)allyl cytidylic acid triphosphate lithium salt; 5-[(3-aminopropoxy)propyl]uracil triphosphate lithium salt; 5-[(3-aminopropoxyFormula:C12H21N4O14P3·xLiPurity:Min. 95%Molecular weight:538.23 g/mol2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine
CAS:2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine is a nucleoside that has antiviral and anticancer effects. It can be used as an activator for phosphoramidites and as a precursor for the synthesis of other nucleosides. 2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine is synthesized from 2,4,6-triisopropylbenzenesulfonyl chloride and 5-(N,N-dimethylamino)valeronitrile in the presence of triethylamine and potassium carbonate in acetonitrile with subsequent purification by silica gel chromatography. The resulting compound is then converted to its diphosphate form by treatment with dithiothreitol in dimethylformamide. This product has been shown to inhibit DNA replication andFormula:C25H23IN2O7Purity:Min. 95%Molecular weight:590.36 g/mol2'-Deoxy-2'-iodo-adenosine-5'-[(beta,gamma)-imido]triphosphate sodium salt - 10mM aqueous solution
CAS:2'-Deoxy-2'-iodo-adenosine-5'-[(beta,gamma)-imido]triphosphate sodium salt - 10mM aqueous solution is a nucleoside that has antiviral activity. It is also used as an anticancer agent and can be used as a monophosphate, diphosphate or activator of deoxyribonucleosides. 2'-Deoxy-2'-iodo-adenosine-5'-[(beta,gamma)-imido]triphosphate sodium salt - 10mM aqueous solution has been modified for use in DNA synthesis. This nucleoside is used to produce phosphoramidites for the synthesis of oligonucleotides and other modified nucleic acid derivatives.
Formula:C10H16N6O11P3IPurity:Min. 95%Molecular weight:616.09 g/molN4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine
N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine is a synthetic nucleoside that inhibits the enzyme ribonucleotide reductase. It has antiviral and anticancer activities.Purity:Min. 95%2'-CMethylcytidine 5'-monophosphate
2'-CMethylcytidine 5'-monophosphate (2'-C-5MP) is a synthetic nucleoside that is chemically modified to inhibit viral replication. 2'-C-5MP inhibits the synthesis of DNA by binding to the polymerase enzyme of the virus and preventing it from synthesizing new DNA strands. This prevents the virus from replicating, which in turn prevents it from spreading through the body. The antiviral activity of 2'-C-5MP has been demonstrated in vitro against herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), respiratory syncytial virus (RSV), and human immunodeficiency virus type 1 (HIV-1). It also has anticancer activity and can be used as an alternative to chemotherapy for treating cancer cells. 2'-C-5MP is a novel compound with high purity and high quality, as evidencedPurity:Min. 95%3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine
CAS:3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine is a novel nucleoside analogue that has been synthesized to inhibit the activity of DNA polymerase. This compound is also an activator of diphosphate and ribonucleoside monophosphate. 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine has been shown to inhibit the replication of herpes simplex virus type 1 in cell culture and the replication of human cytomegalovirus in cell culture. 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-- 2'-fluoroarabinocytidine does not have any antiviral activity against HIV.Purity:Min. 95%4-Amino-2-chloro-5-fluoropyrimidine
CAS:4-Amino-2-chloro-5-fluoropyrimidine is a chlorinating agent that is used in the synthesis of 4,5-dichloropyrimidine and 4,6-dichloropyrimidine. It is also used for the synthesis of oxychloride by reacting with phosphorus oxychloride or phosphorus.Purity:Min. 95%N4-Benzoyl-2'-deoxy-5-iodocytidine
CAS:N4-Benzoyl-2'-deoxy-5-iodocytidine is a nucleoside that is used as an activator for RNA synthesis and in the synthesis of phosphoramidites. It has antiviral and anticancer properties and is novel for its potential use as a therapeutic agent.Formula:C16H18IN3O4Purity:Min. 95%Molecular weight:443.24 g/mol2'-Deoxy-5'-O-DMT-uridine succinyl 3'-CPG
2'-Deoxy-5'-O-DMT-uridine succinyl 3'-CPG is a novel, synthetic, high purity, and high quality activator for oligonucleotide synthesis. It is a modified nucleoside with a 2' -deoxy-5'-O-dimethoxytrityl group attached to the sugar moiety. This product is used in monophosphate form and can be used as an anticancer agent. This product has antiviral activity, which may be due to its ability to inhibit viral DNA and RNA synthesis.Purity:Min. 95%antisense
Antisense is a type of experimental therapy that uses a single-stranded RNA molecule to bind to complementary RNA molecules, blocking their function. Antisense rna is often used in gene regulation and chromatin remodeling. It also regulates the transcription of mRNA by binding to the messenger RNA molecule as it leaves the nucleus. The main output of antisense is an increase in the production of one type of protein or a decrease in another. Antisense has been shown to be effective in regulating gene expression and can be used to treat diseases such as cancer and autoimmune disorders.Purity:Min. 95%2'-Deoxy-5'-O-DMT-guanosine-(iBu)-3'-succinyl CPG 2000 Å
2'-Deoxy-5'-O-DMT-guanosine-(iBu)-3'-succinyl CPG 2000 Å is a novel, high quality, and modified nucleoside that can be used in the synthesis of DNA and RNA. It is a phosphoramidite monophosphate that has antiviral and anticancer properties. It can also be used as an activator for the synthesis of oligonucleotides.
Purity:Min. 95%2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-H phosphonate triethylammonium salt
CAS:2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-H phosphonate triethylammonium salt is a novel nucleoside analog. It has been shown to be cytotoxic to cancer cells in vitro and in vivo. 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-H phosphonate triethylammonium salt inhibits viral replication, including herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1), by inhibiting DNA synthesis.Formula:C35H37N5O9PPurity:Min. 95%Molecular weight:804.89 g/mol2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt - 10mM aqueous solution
CAS:2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt - 10mM aqueous solution is an antiviral nucleoside phosphoramidite that is used in the synthesis of deoxyribonucleosides. It has been shown to be effective against some DNA viruses and has anticancer activity. 2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt - 10mM aqueous solution is synthesized from 2',3',4',5',6-pentakis(2-hydroxypropyl)carbamate and 2-deoxyuridine 5'-monophosphate.Formula:C9H16N3O13P3Purity:Min. 95%Color and Shape:liquid.Molecular weight:467.16 g/molEthynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite
CAS:Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite is a monophosphate nucleoside analog. The ethynyl group is attached to the 2'-hydroxyl group of the ribose sugar. This nucleotide analogue inhibits DNA and RNA synthesis by inhibiting DNA polymerase and RNA polymerase. Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite has antiviral activity against Herpes simplex virus type 1 (HSV1) and type 2 (HSV2) in vitro, as well as cytotoxic activity against human leukemia cells in vitro.Formula:C37H45N2O6PPurity:Min. 95%Molecular weight:644.74 g/mol3',5'-Di-o-acetyl-O6-phenyl-2'-deoxyinosine
CAS:3',5'-Di-O-acetyl-O6-phenyl-2'-deoxyinosine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the enzyme ribonucleotide reductase and has been shown to be effective against herpes simplex virus type 1 and 2, cytomegalovirus, Epstein Barr virus, human immunodeficiency virus type 1, and Kaposi sarcoma cells. 3',5'-Di-O-acetyl-O6-phenyl-2'-deoxyinosine also inhibits the production of tumor necrosis factor alpha (TNFα), which can cause inflammatory reactions in the body. This compound is a modified nucleoside with high purity and quality. It has CAS number 133471-06-4.Formula:C20H20N4O6Purity:Min. 95%Molecular weight:412.4 g/mol2-(Propylthio)pyrimidine-5-carbaldehyde
CAS:2-(Propylthio)pyrimidine-5-carbaldehyde (2-PSPCA) is a novel, modified ribonucleoside that has been shown to activate the DNA polymerase. 2-PSPCA has been used in the synthesis of deoxyribonucleosides and phosphoramidites for use in the research and development of antiviral agents and anticancer drugs. 2-PSPCA is a monophosphate with an IC50 of 0.6 mM against human leukemia cells.Formula:C8H10N2OSPurity:Min. 95%Molecular weight:182.24 g/mol3'-O-Aminoacetoxy-2'-deoxyadenosine 5'-O-triphosphate triethylammonium salt
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Formula:C13H21N6P3O12•NaxPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:546.26 g/mol6-Chloropurine riboside 5'-monophosphate disodium salt
CAS:6-Chloropurine riboside 5'-monophosphate disodium salt is a synthetic nucleoside that is used as an antiviral and anticancer agent. It is a DNA precursor that can be incorporated into DNA by the enzyme thymidylate synthase to form thymine and diphosphate. 6-Chloropurine riboside 5'-monophosphate disodium salt has been shown to inhibit the replication of some viruses, such as HIV, and also inhibits tumor growth in experimental models.Formula:C10H10ClN4Na2O7PH2OPurity:Min. 95%Molecular weight:428.63 g/mol3'-Deoxy-N2-DMF-5'-O-DMT-guanosine
CAS:3'-Deoxy-N2-DMF-5'-O-DMT-guanosine is a modified nucleoside that is phosphorylated to the 3'-deoxyribonucleotide form. It has antiviral and anticancer activities, as well as being an activator of DNA and RNA synthesis. This compound has been shown to inhibit the growth of several cancer cell lines in vitro and in vivo. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine is also effective against herpes simplex virus type 1 (HSV1) and HSV type 2 in cell culture, although it does not have any effect on HSV type 1 replication in animal models.Formula:C34H36N6O6Purity:Min. 95%Molecular weight:624.69 g/mol6-Pyrrolidino-7-deazapurine
CAS:6-Pyrrolidino-7-deazapurine is a monophosphate nucleoside, which is a synthetic nucleotide. It has been shown to activate DNA synthesis and inhibit the growth of tumor cells. 6-Pyrrolidino-7-deazapurine has also been shown to be active against viruses, such as herpes, by inhibiting their replication. This product is stable at room temperature for up to one year and can be stored at -20°C for up to three years. The purity of this product is >98% with no detectable impurities.
Formula:C10H12N4Purity:Min. 95%Molecular weight:188.23 g/mol4-Amino-6-methyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone
CAS:4-Amino-6-methyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone (4AMD) is an adenosine analog that is fluorescent. 4AMD is not hydrolyzed by adenosine deaminase and has a higher affinity for the A1 receptor than for the A2a receptor. This makes it a useful probe for the study of adenosine mediated, yields, and analogs. The fluorescence properties of 4AMD were studied in different solvents at various temperatures to monitor the interaction of 4AMD with catalysis. The monomeric form of 4AMD was used to measure its fluorescence properties.Formula:C12H15N5O4Purity:Min. 95%Molecular weight:293.28 g/mol5'-O-DMT-4-thiouridine
5'-O-DMT-4-thiouridine is a nucleoside analog that is used as a research tool in anticancer and antiviral studies. It is an activator of the phosphatase PP1 and has been shown to inhibit the growth of cultured human leukemia cells by inhibiting DNA synthesis. This compound has also been shown to be an inhibitor of HIV replication in vitro and in vivo, but it is not active against other viruses. 5'-O-DMT-4-thiouridine can be synthesized from uracil, 4-thiouracil, and DMT (dimethoxytrityl) using standard phosphoramidite chemistry. The purity of this compound is greater than 99%, and it can be obtained for use at a reasonable price.
Formula:C30H30N2O7SPurity:Min. 95%Molecular weight:562.64 g/mol2',3'-Dideoxy-3'-fluorocytidine
CAS:2',3'-Dideoxy-3'-fluorocytidine is a synthetic nucleoside analog that inhibits DNA synthesis by blocking the incorporation of deoxycytidine into DNA. It is used to treat lymphocytic leukemia, hepatitis, and virus infections. 2',3'-Dideoxy-3'-fluorocytidine has been shown to inhibit cell growth in solid tumours. The drug has also been shown to inhibit the production of immunodeficiency viruses such as human immunodeficiency virus type 1 (HIV-1) and human T-lymphotropic virus type I (HTLV-I), which causes acquired immune deficiency syndrome (AIDS). 2',3'-Dideoxy-3'-fluorocytidine inhibits viral replication by inhibiting the activity of the enzyme deaminase, which converts dATP to dTTP. This prevents DNA replication and transcription.Formula:C9H12FN3O3Purity:Min. 95%Molecular weight:229.21 g/mol4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine
CAS:4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine is a novel nucleoside analogue that has high purity and high quality. It is an activator of DNA synthesis, diphosphate and monophosphate of deoxyribonucleosides, ribonucleosides and analogues. 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine has been shown to have antiviral activities against herpes simplex virus type 1 (HSV1) in cell culture.Formula:C29H56N4O4Si3Purity:Min. 95%Molecular weight:609.04 g/mol2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite)
CAS:Please enquire for more information about 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C56H61N8O12PPurity:Min. 95%Molecular weight:1,069.1 g/mol7H-Pyrrolo[2,3d]pyrimidine
CAS:7H-Pyrrolo[2,3d]pyrimidine is a pyrimidine compound that has been shown to have potent antitumor activity. It inhibits the enzyme acyl-coenzyme A carboxylase (ACC) and blocks the production of malonyl-CoA, an intermediate in the metabolism of fatty acids. Malonyl-CoA is an allosteric activator of ACC, which is an important enzyme for regulating fatty acid synthesis. 7H-Pyrrolo[2,3d]pyrimidine also inhibits the expression of the gene encoding cb2 receptor, which is involved in inflammatory processes. The compound binds to a hydroxyl group on ACC to inhibit its activity. 7H-Pyrrolo[2,3d]pyrimidine has been shown to be effective against miapaca-2 cells and other cancer cell lines at concentrations as low as 1 nM. This compound also has aFormula:C6H5N3Purity:Min. 95%Molecular weight:119.12 g/mol2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine
CAS:2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine (ABT-888) is a nucleoside analog that inhibits DNA synthesis and RNA transcription. It has been shown to induce apoptosis in human cancer cells, including leukemia, lymphoma and breast cancer cells. ABT-888 also has antiviral activity against herpes simplex virus type 1 and 2, vaccinia virus, and vesicular stomatitis virus.Formula:C19H20N2O7Purity:Min. 95%Molecular weight:388.37 g/molN6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine
CAS:N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine is a novel nucleoside that has been shown to have anticancer and antiviral properties. It is a phosphoramidite of 7-iodoadenosine that has been modified to contain a benzoyl group at the 6 position. N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-(7)iodoadenosine can be used for the synthesis of oligonucleotides and DNA, as well as for the activation of latent HIV genes. This compound is also used in vitro to study the interactions between phosphoramidites and nucleosides.Formula:C24H31IN4O4SiPurity:Min. 95%Molecular weight:594.52 g/mol1-(a-D-Mannopyranosyl)thymine
CAS:1-(a-D-Mannopyranosyl)thymine is a phosphoramidite nucleoside with antiviral activity. It is an analog of thymine, in which the oxygen atom at the 5-position has been replaced by a mannose group and the hydroxyl group at the 4-position has been replaced by a methyl group. This compound has shown to have anticancer properties as well as inhibitory effects on HIV replication. Studies have also shown that 1-(a-D-mannopyranosyl)thymine inhibits proliferation and induces apoptosis in human cancer cell lines.Formula:C11H16N2O7Purity:Min. 95%Color and Shape:Light (Or Pale) Yellow SolidMolecular weight:288.75 g/molN4-Anisoyl-2'-deoxycytidine
CAS:N4-Anisoyl-2'-deoxycytidine is a nucleoside that contains a long chain of four carbon atoms. It is the cyclic form of N4-anisoyl-2'-deoxyadenosine. This compound has been shown to be synthesized in yields of up to 71% using acid anhydrides and diamino compounds. N4-Anisoyl-2'-deoxycytidine is a bifunctional reagent that can be used as a starting material for the synthesis of oligodeoxyribonucleotides. The compound has also been shown to function as an effective inhibitor of DNA synthesis, which may lead to anti-cancer effects.Formula:C17H19N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:361.35 g/mol5-Ethynylpyrimidine
CAS:5-Ethynylpyrimidine is a supramolecular alkynyl group that has been shown to inhibit tyrosine kinase activity, cross-coupling, and the synthesis of proteins. It also exhibits luminescent properties and can be used in supramolecular chemistry. 5-Ethynylpyrimidine is a pyrimidine nucleoside, which is an organic compound that is a component of RNA. Pyrimidine nucleosides are important for protein synthesis and are used as luminophores or fluorescent resonance quenchers in biochemical assays for enzyme activity; they have also been shown to inhibit herpes simplex virus (HSV) replication. 5-Ethynylpyrimidine has been found to be able to bind terminal alkynes with high affinity.Formula:C6H4N2Purity:Min. 95%Molecular weight:104.11 g/molAICAR 3',5'-cyclic phosphate
CAS:AICAR 3',5'-cyclic phosphate is an antiviral and anticancer agent that inhibits the production of DNA and RNA, which may be due to its ability to activate AMP-activated protein kinase. AICAR 3',5'-cyclic phosphate has been shown to inhibit the proliferation of human breast cancer cells in vitro. This drug also has anticancer activity against various types of cancers, including prostate cancer and melanoma. AICAR 3',5'-cyclic phosphate is a novel compound that can be used as a phosphoramidite reagent for the synthesis of oligonucleotides.
Formula:C9H13N4O7PPurity:Min. 95%Molecular weight:320.2 g/mol3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite
CAS:3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite is a nucleotide analogue that is used in the synthesis of DNA. It is a modified nucleoside that contains an amino group at the 5' position of the pentose sugar and a methyl group at the 2' position. 3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite inhibits viral replication and has shown anticancer activity. It also possesses antiviral activity against Herpes simplex virus types 1 and 2, cytomegalovirus, varicella zoster virus, Epstein Barr virus, influenza A virus type A/PR/8/34 (H1N1), and human immunodeficiency virus type 1 (HIV).Formula:C40H49N4O8PPurity:Min. 95%Molecular weight:744.81 g/mol7’-OH-N-trityl morpholino uracil
CAS:Please enquire for more information about 7’-OH-N-trityl morpholino uracil including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C28H27N3O4Molecular weight:469.53 g/mol5'-Azido-2',5'-dideoxyinosine
CAS:5'-Azido-2',5'-dideoxyinosine is a novel nucleoside which has been synthesized to investigate its anticancer and antiviral properties. 5'-Azido-2',5'-dideoxyinosine is an activator of ribonucleosides and deoxyribonucleosides, converting them into the corresponding monophosphate or diphosphate form. This product can be used as a building block for the synthesis of phosphoramidites and modified nucleosides. 5'-Azido-2',5'-dideoxyinosine has shown activity against cancer cells in vitro, in particular leukemia cell lines. It also has antiviral activity against HIV, herpes simplex virus type 1, and human cytomegalovirus (HCMV).Formula:C10H11N7O3Purity:Min. 95%Molecular weight:277.24 g/mol2',3'-Dideoxy-N2-isobutyrylguanosine
2',3'-Dideoxy-N2-isobutyrylguanosine is a monophosphate that inhibits viral replication by competing with the natural substrate, diphosphate. It is synthesized in high purity and quality by our company. 2',3'-Dideoxy-N2-isobutyrylguanosine has been used as an antiviral agent to inhibit the hepatitis B virus. This product is also of interest for its potential use in cancer treatment.
Formula:C14H19N5O4Purity:Min. 95%Molecular weight:321.34 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Q linker CPG 1000Å
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Q linker CPG 1000Å is a nucleoside analog that is used in the synthesis of DNA. It is a phosphoramidite that has been modified with an acetyl group at the 2' position and a Q linker at the 3' position. This product can be used as an antiviral or anticancer agent, as well as for other research purposes. The CAS number for this product is 62660-67-7, and it has been shown to be active against HIV and HCV.Purity:Min. 95%
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