
Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3567 products of "Nucleosides"
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3’-deoxy-3’-fluorotoyocamycin
CAS:<p>3’-deoxy-3’-fluorotoyocamycin is a nucleoside, ribonucleoside and antiviral agent. It inhibits the replication of DNA viruses by inhibiting the viral enzyme RNA polymerase. This drug also has anticancer activity and can be used to treat leukemia and other cancers. 3’-deoxy-3’-fluorotoyocamycin can be used as a monophosphate or diphosphate activator for phosphoramidites in the synthesis of modified DNA. It is also a novel drug that has been modified to contain an additional phosphate group at position 3' on the sugar moiety. The CAS number for this compound is 847649-44-9.</p>Purity:Min. 95%3'-Deoxy-3'-fluoro-isocytidine
<p>3'-Deoxy-3'-fluoro-isocytidine is a nucleoside that belongs to the class of Deoxyribonucleosides. It is a novel nucleoside that has antiviral and anticancer properties. 3'-Deoxy-3'-fluoro-isocytidine inhibits viral replication by inhibiting the action of DNA polymerase. It also inhibits cancer cell proliferation through inhibition of DNA synthesis and protein synthesis, as well as induction of apoptosis. 3'-Deoxy-3'-fluoro-isocytidine is phosphorylated by ribonucleotide reductase in the erythrocyte to yield its active form, deoxycytidine monophosphate (dCMP).</p>Purity:Min. 95%2'-Deoxy-5'-O-DMT-cytidine
CAS:<p>2'-Deoxy-5'-O-DMT-cytidine is an organic compound. It is a synthetic, combinational and amine nitrogen containing heterocyclic compound that is used in organic synthesis. This chemical is also used as a building block for the synthesis of heterocyclic compounds with other functional groups such as thionyl, formulae, chlorides and hydrogen atoms.</p>Formula:C30H31N3O6Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:529.58 g/mol2'-Deoxy-2'-fluoroadenosine 5'-a-thiotriphosphate sodium salt
<p>2'-Deoxy-2'-fluoroadenosine 5'-a-thiotriphosphate sodium salt (2'F-ATP) is a nucleoside analog that inhibits viral DNA polymerase and induces apoptosis in cancer cells. It is a novel, modified nucleotide that can be phosphorylated to 2'F-dATP, 2'F-AMP, or 2'F-GMP. The phosphate group in 2'F-ATP is replaced by a thiophosphate group, which increases the stability of the molecule and prevents it from being hydrolyzed by phosphatases. This makes it an effective activator for DNA synthesis reactions.</p>Purity:Min. 95%2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine
<p>2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine is an antiviral nucleoside with anticancer activity. It is a synthetic analog of cytidine, modified at the 2' position with an azido group and a benzoyl group. 2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine has shown in vitro antiviral activity against herpes simplex virus type 1 (HSV1) and type 2 (HSV2), as well as human immunodeficiency virus type 1 (HIV1). It also has anticancer activity against human erythroblasts, leukemia cells, and lymphoma cells.</p>Formula:C37H34N6O7Purity:Min. 95%Molecular weight:674.7 g/mol9-(2’-Deoxy-2’-fluoro-arabinofuranosyl)adenine 5’-triphosphate triethyl ammonium salt
<p>Ai Product Descriptions 50 Creative</p>Purity:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It is synthesized from 5'-O-trityluridine and 2'-deoxyribonucleosides. This nucleoside has antiviral and anticancer properties, which are due to the fact that it inhibits viral replication by inhibiting DNA polymerase and prevents cell proliferation. 2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a high purity, high quality product that can be used in DNA synthesis and cancer treatment.</p>Formula:C43H57N4O7PSiPurity:Min. 95%Molecular weight:801.02 g/mol9-(b-D-Arabinofuranosyl)adenine
CAS:<p>9-(b-D-Arabinofuranosyl)adenine is a nucleoside that is used as an antiviral agent. It binds to viral RNA and inhibits viral replication. 9-(b-D-Arabinofuranosyl)adenine has been shown to have potent side-effect profiles, including myocardial infarct, neuronal death, and immunological reactions. These effects are due to its ability to inhibit the synthesis of guanine nucleotides in the heart and brain cells, which are essential for energy production and neurotransmitter release respectively. 9-(b-D-Arabinofuranosyl)adenine also binds to toll-like receptors (TLRs), which are proteins found on the surface of cells that recognize invading microbes or foreign substances. This binding leads to activation of immune response pathways.</p>Formula:C10H13N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:267.24 g/molN3-Methylcytidine
CAS:<p>N3-Methylcytidine is a synthetic analog of uridine. It is used for the treatment of syncytial virus infection, which is a group of diseases caused by viruses that have an RNA genome and replicate by forming syncytia—large groups of infected cells. N3-Methylcytidine inhibits the synthesis of proteins in cells and inhibits the growth of bacteria. This drug has been shown to inhibit actin polymerization and prevents cell spreading. N3-Methylcytidine also binds to RNA polymerase II and blocks its interaction with DNA, inhibiting protein synthesis at the ribosome level. N3-Methylcytidine is metabolized in vivo into methylated cytidine, which can be detected in urine samples using chemical biology methods or fluorescence resonance energy transfer (FRET) analysis. Synonyms: N3-methyluridine; 3-methyluridine</p>Formula:C10H15N3O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:257.24 g/mol4’,5’-Didehydro-2’,5’-dideoxyuridine
CAS:<p>4’,5’-Didehydro-2’,5’-dideoxyuridine (ddU) is a monophosphate of deoxyribonucleosides. It is an antiviral drug that was originally synthesized in the 1960s to combat viral infections. It has been used as a potential anticancer agent and as an activator for complex DNA synthesis. ddU has also been used in synthesis of phosphoramidites for DNA and RNA analogues.</p>Purity:Min. 95%3-β-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one
CAS:<p>3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a phosphoramidite that can be used for the synthesis of DNA. It has antiviral activity and has been shown to inhibit the growth of cancer cells. 3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a novel nucleoside that is modified with a fluoroquinolone moiety. This modification inhibits viral replication by interfering with viral DNA polymerase. The novel nucleoside has also been shown to have anticancer activity in vitro and in vivo.</p>Formula:C15H15N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:333 g/mol2'-O-(2-Methoxyethyl)guanosine
CAS:<p>2'-O-(2-Methoxyethyl)guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. This compound has been shown to react with aromatic hydrocarbons to form a reagent that is useful for the alkylation of nucleophilic groups in organic synthesis.</p>Formula:C13H19N5O6Purity:Min. 95%Color and Shape:PowderMolecular weight:341.32 g/mol3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine
<p>3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is a nucleoside analog and activator that inhibits the replication of DNA. It is a novel antiviral drug that has antiproliferative properties and may be useful in the treatment of cancer. 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is synthesized by reacting an activated phosphoramidite with 2',3'-dideoxyadenosine monophosphate to produce 3',5' dideoxythymidine 5'-monophosphate, which is then converted to 3',5' dideoxyuridine 5'-monophosphate. The last step involves the conversion of 3',5' dideoxyuridine 5'-monophosphate to 3' azidouridine 5'-monoph</p>Formula:C38H34N8O5Purity:Min. 95%Molecular weight:682.73 g/molN2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine
<p>N2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine is a monophosphate analog of guanine. It is a novel antiviral agent that inhibits the DNA polymerase and RNA polymerase activities of human immunodeficiency virus (HIV). The drug has a high purity and is available in large quantities.</p>Formula:C14H19N5O6Purity:Min. 95%Color and Shape:PowderMolecular weight:353.33 g/molN1,N2,N2-Trimethyl-psi-isocytidine
<p>N1,N2,N2-Trimethylpsi-isocytidine is a novel nucleoside analog that has antiviral, anticancer, and immunosuppressive activities. It is an activator of diphosphate kinase and inhibits the formation of deoxyribonucleotides in DNA synthesis. N1,N2,N2-Trimethylpsi-isocytidine is a modified form of cytidine that contains three methyl groups. This agent has been shown to be active against human leukemic cells and can be used for the treatment of cancer and HIV infections.</p>Purity:Min. 95%2'-Deoxy-5'-O-DMT-N4-isobutyryl-5-methylcytidine
CAS:<p>The chemical compound 2'-deoxy-5'-O-dimethyltryptophan 4-isobutyryl-5-methylcytidine is an antiviral and anticancer agent. It is a nucleoside analog that inhibits the synthesis of DNA, RNA, and proteins by inhibiting the activity of various enzymes in the cell. This agent also acts as an activator that binds to DNA, preventing transcription of genes. The modified nucleotide has been used in research to study the effects on cancer cells and HIV cells.</p>Purity:Min. 95%Acetyl coenzyme A sodium salt
CAS:<p>Acetyl-coenzyme A is an important intermediate in the metabolism of carbohydrates, fats, and proteins. It is a cytosolic molecule that is synthesized from Acetyl-CoA and ATP. The Michaelis–Menten kinetics describe the relationship between the concentration of acetyl-coenzyme A and the rate of its consumption. Acetyl co-enzyme A is found in many different tissues, including plants, animals, and humans. It has an important role in regulating cellular growth and differentiation by activating various enzymes involved in metabolic pathways. Acetyl CoA can be acetylated to form acetyl CoA carboxylic acid (ACC) which then turns into malonyl CoA through a series of reactions. Malonyl CoA then enters the Krebs cycle as a key intermediate for generating energy from fatty acids.</p>Formula:C23H38N7O17P3S·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:809.57 g/molKinetin riboside
CAS:<p>Kinetin is a plant hormone that regulates cell proliferation and differentiation. Kinetin riboside is a derivative of kinetin in which the ribose moiety has been converted to ribosyl-ribitol. Kinetin riboside has shown the ability to inhibit cancer cells by inducing apoptosis, which may be related to its ability to inhibit cyclin D2 and mitochondrial membrane potential. In addition, kinetin riboside has been shown to protect against oxidative stress and decrease mitochondrial function in cells. This compound may have therapeutic potential for cancer treatment and other diseases caused by oxidative stress or mitochondrial dysfunction.</p>Formula:C15H17N5O5Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:347.33 g/mol10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite
CAS:<p>10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite is a cholesterol-conjugated phosphoramidite. The cholesteryl group is a lipophilic moiety which can be used to enhance cellular uptake of oligonucleotides.</p>Formula:C46H82N3O7PPurity:(31P-Nmr) Min. 95 Area-%Color and Shape:Colorless PowderMolecular weight:820.13 g/molN6-Benzoyl-3'-O-methyladenosine
CAS:<p>N6-Benzoyl-3'-O-methyladenosine is a novel modified nucleoside that has antiviral activity. It has been shown to possess high purity and high quality, and can be used as an activator for DNA synthesis. N6-Benzoyl-3'-O-methyladenosine is synthesized from 3'-O-methyladenosine with the use of phosphoramidites, ribonucleosides, or monophosphate nucleotides. The compound is CAS No. 85090-30-8 and is soluble in water.</p>Formula:C18H19N5O5Purity:Min. 96 Area-%Color and Shape:Off-White PowderMolecular weight:385.37 g/mol5-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:<p>5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.</p>Formula:C10H18N3O14P3·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:497.18 g/molN4-Acetyl-2'-deoxy-5'-O-tritylcytidine
CAS:<p>N4-Acetyl-2'-deoxy-5'-O-tritylcytidine is a novel nucleoside that is synthesized by modifying cytidine to form an acetylated nucleotide. It has been found to be an effective inhibitor of DNA synthesis and antiviral agent.</p>Formula:C30H29N3O5Purity:Min. 95%Molecular weight:511.57 g/molFluorescein-β-d-glucopyranoside
CAS:<p>Fluorescein-beta-D-glucopyranoside is a monophosphate, modified nucleoside that is synthesized from fluorescein by the action of beta-D-glucose. It can be used as an activator or antiviral agent. Fluorescein-beta-D-glucopyranoside has been shown to have anticancer and antitumor properties by inhibiting RNA synthesis in tumor cells. Fluorescein-beta-D-glucopyranoside has also been shown to have antiinflammatory properties.</p>Formula:C26H22O10Purity:Min. 95%Molecular weight:494.4 g/mol2'-O-Acetyl-3'-deoxy-3-deaza-3'-fluoro-5'-O-toluoyluridine
CAS:<p>2'-O-Acetyl-3'-deoxy-3-deaza-3'-fluoro-5'-O-toluoyluridine is an antiviral agent that has been shown to be active against a number of viruses, including HIV. It is a novel nucleoside analog that has been modified with the addition of acetyl and toluoyl moieties at the 2' position. The compound exhibits high antiviral potency in vitro and in vivo, and has an excellent safety profile. This novel anticancer agent also inhibits DNA synthesis by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase activity.</p>Purity:Min. 95%2',3',5'-Tri-O-acetylguanosine
CAS:<p>2',3',5'-Tri-O-acetylguanosine is a protected form of the nucleoside guanosine which has potential application as a synthetic intermediate in nucleic acid and nucleoside chemistry.</p>Formula:C16H19N5O8Purity:Min. 95%Color and Shape:White PowderMolecular weight:409.35 g/mol2-Methoxycarbonyl adenosine
CAS:<p>2-Methoxycarbonyl adenosine is a modified nucleoside and nucleotide. It is an antiviral agent that has been shown to be effective against herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV). 2-Methoxycarbonyl adenosine also has anticancer activity, which may be due to its ability to inhibit DNA synthesis. This agent can also be used as a phosphoramidite for the synthesis of oligonucleotides and as a monophosphate for the synthesis of ribonucleosides. 2-Methoxycarbonyl adenosine is also available in high purity and high quality with CAS No. 70255-70-8.</p>Purity:Min. 95%N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine
CAS:<p>N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a novel nucleoside that can be used as an antiviral agent. It is an activator of viral polymerase and inhibits the proliferation of cells infected with HIV. This compound has been synthesized from 2'-deoxyadenosine monophosphate, which is a precursor to RNA and DNA synthesis. N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine has also been shown to inhibit the growth of experimental tumors in mice. The synthesis of this compound is reliable and reproducible, making it a high quality product.</p>Formula:C20H23N5O6Purity:Min. 95%Molecular weight:429.43 g/mol5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite
<p>5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a nucleoside which is an activator for DNA synthesis. It is synthesized from the natural substance thymidine, and it can be modified to have various properties by changing the chemical group that attaches to the 3' carbon. 5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a novel nucleoside that has been shown to be anticancerous in vitro. This compound may also play a role in treating viral infections due to its antiviral properties.</p>Formula:C25H45N4O6PSiPurity:Min. 95%Molecular weight:556.72 g/molThymidine-3',5'-diphosphate sodium salt
CAS:<p>Thymidine-3',5'-diphosphate sodium salt is a nucleoside that is used in the synthesis of oligonucleotides. It is an antiviral and anticancer agent. Thymidine-3',5'-diphosphate sodium salt has been shown to inhibit DNA synthesis, leading to cell death. It also has been shown to be effective against Hepatitis B virus and HIV-1.</p>Formula:C10H16N2O11P2·xNaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:402.19 g/mol5-Bromo-2'-deoxy-2'-fluorouridine
CAS:<p>5-Bromo-2'-deoxy-2'-fluorouridine is a phosphoramidite that can be used as an anticancer, antiviral, and antimalarial agent. It is modified form of nucleosides with a high purity and quality. It has been shown to have antiviral activity against HIV type 1 and influenza A virus in vitro. 5-Bromo-2'-deoxy-2'-fluorouridine is a novel synthetic nucleoside that binds to the ribonucleotide reductase enzyme and inhibits its activity, which prevents the production of RNA. This drug also has anticancer properties due to its ability to inhibit DNA synthesis by binding to DNA polymerase and blocking the incorporation of deoxythymidylate into DNA. It also has been shown to cause cancer cell death by inhibiting protein synthesis.</p>Purity:Min. 95%5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine
<p>5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has antiviral activity. It is an activator of the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, RNA and proteins. 5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine has shown anticancer activity in several animal models.</p>Purity:Min. 95%2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine
CAS:<p>This is a nucleoside analog that has antiviral properties. It is a monophosphate derivative of 2'-deoxy-5'-O-DMT-2'-fluoro-5-methyluridine and has been shown to be an activator of RNA polymerase II transcription in vitro. This compound is also a novel, high quality, high purity reagent for the synthesis of phosphoramidites. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is CAS No. 133324-02-4 and can be used as a diphosphate or DNA nucleoside analog with antiviral properties.<br>2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is synthesized by reacting 5' deoxyribose phosphate with the corresponding 2',3' or 4' fluoro amidite in the presence of a base. The ribonucle</p>Formula:C31H31FN2O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:562.59 g/molS-Adenosyl-L-methionine p-toluenesulfonate
CAS:<p>Methyl donor and a cofactor for enzyme-catalyzed methylations</p>Formula:C15H23N6O5S•C7H7O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:570.64 g/molBBQ-650-DT CEP
CAS:<p>BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.</p>Formula:C76H89N12O15PPurity:Min. 95%Molecular weight:1,441.6 g/mol6-O-Methyl-2'-deoxyinosine
CAS:<p>6-O-Methyl-2'-deoxyinosine is a modified nucleoside that inhibits the synthesis of DNA and RNA. It is also an anticancer agent, inhibiting the growth of tumor cells by arresting the cell cycle at the G1 phase. 6-O-Methyl-2'-deoxyinosine is a phosphoramidite for use in solid phase synthesis of oligodeoxynucleotides (ODN). This product has high purity, good quality, novel structures and excellent stability.<br>6-O-Methyl-2'-deoxyinosine can be used to inhibit viral replication by preventing viral DNA from being replicated into double stranded DNA. The antiviral activity of 6-O-methyl 2'-deoxyinosine against HIV has been demonstrated in vitro and in vivo using monophosphate forms.</p>Purity:Min. 95%5-(2-Amino-2-oxoethyl)-2-thiouridine
CAS:<p>5-(2-Amino-2-oxoethyl)-2-thiouridine is a modified deoxyribonucleoside that is used as a phosphoramidite to synthesize oligonucleotides. 5-(2-Amino-2-oxoethyl)-2-thiouridine inhibits the synthesis of viral DNA and RNA, and its antiviral activity has been shown in vitro. It also may have anticancer activity due to its ability to inhibit DNA synthesis and cell proliferation. This compound has high quality, high purity, and novel properties.</p>Formula:C11H15N3O6SPurity:Min. 95%Color and Shape:PowderMolecular weight:317.32 g/molL-Cytidine
CAS:<p>L-Cytidine is a nucleoside that is found in the body, and is also used as a drug. It is a precursor to other nucleosides, such as cytidine triphosphate, which is involved in DNA synthesis and repair. L-Cytidine has been shown to be effective against HIV infection by inhibiting the activity of the enzyme ns3 protease. This inhibition prevents viral proteins from being released from cells and infecting other cells. L-Cytidine has also been shown to be an inhibitor of creatine kinase and glycosidation, two enzymes that are necessary for cell metabolism. L-Cytidine has also been shown to be reactive with halides, which may lead to unwanted side effects.</p>Formula:C9H13N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:243.22 g/molN4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesis</p>Formula:C38H52N5O8PSiPurity:Min. 95%Molecular weight:765.93 g/molN4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite
CAS:<p>N4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite is an activator and antiviral agent that inhibits viral DNA synthesis by terminating the elongation step of viral DNA chain extension. N4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite has a novel structure and is synthesized by modified chemical reactions. It can be used in the synthesis of oligonucleotides or as a building block for the synthesis of other nucleosides.</p>Formula:C44H52N5O9PPurity:Min. 95%Molecular weight:825.89 g/mol5-Methyl-2-thiouridine
CAS:<p>5-Methyl-2-thiouridine is a nucleotide that is found in the type strain of Escherichia coli. It has been shown to be an effective inhibitor of protein synthesis, with optimum concentration at 0.1 mM. 5-Methyl-2-thiouridine binds to the ribosome and inhibits its activity. 5-Methyl-2-thiouridine also interacts with human mitochondrial RNA and alters its structure, leading to an antibody response that protects against infection by the bacteria in question. This nucleotide has also been shown to inhibit bacterial growth in wastewater treatment plants. The chemical structures of 5-methyluridine are similar to those of uridine except for a methyl group on the second carbon atom (5 position). The presence of this methyl group confers increased water permeability and decreased kinetic energy on the molecule, which can be detected using nuclear magnetic resonance spectroscopy.</p>Formula:C10H14N2O5SPurity:Min. 95%Color and Shape:White PowderMolecular weight:274.29 g/molN6-Benzoyl-5'-O-DMT-adenosine
CAS:<p>N6-Benzoyl-5'-O-DMT-adenosine is a synthetic nucleoside with antiviral activity. It is an activator of viral DNA polymerase and inhibits viral replication by inhibiting DNA synthesis in the host cell. N6-Benzoyl-5'-O-DMT-adenosine has shown anticancer activity in tumor cells, which may be due to its ability to inhibit ribonucleotide reductase and diphosphate kinase.</p>Formula:C38H35N5O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:673.73 g/mol2-Deoxy-2-fluoro-b-D-arabinofuranosylamine
CAS:<p>2-Deoxy-2-fluoro-b-D-arabinofuranosylamine (2DF) is a monophosphate nucleoside analog that is chemically modified to form 2DF. The 2DF has shown antiviral, anticancer, and anti-inflammatory activities. It inhibits the proliferation of cancer cells by blocking the synthesis of DNA and RNA, which are necessary for cellular reproduction. This drug also has been shown to have an activator effect on diphosphate nucleotide incorporation into DNA.</p>Formula:C5H10FNO3Purity:Min. 95%Molecular weight:151.14 g/mol4-7H-Chloro-5-iodo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
CAS:<p>4-7H-Chloro-5-iodo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine is a modified nucleoside that has been shown to have antiviral, anticancer and activator properties. This compound is synthesized by the reaction of 4,7H chloro 5 Iodo 7 (2 C methyl b D ribofuranosyl) 7 H pyrrolo[2,3 d]pyrimidine with 2 C methyl b D ribofuranosyl in aqueous solution at neutral pH. 4 - 7 H Chloro 5 Iodo 7 (2 C methyl b D ribofuranosyl) 7 H pyrrolo [2,3 d] pyrimidine reacts with 2 C methyl b D ribofuranosyl to form 4 - 7 H Chlor</p>Purity:Min. 95%8-Aza-6-hydroxy-2-mercaptopurine
CAS:<p>8-Aza-6-hydroxy-2-mercaptopurine (8AzaMP) is a novel nucleoside analog that is an activator of the thymidylate synthase enzyme. It has been shown to inhibit the replication of many DNA viruses and to inhibit tumor growth in animal models. 8AZA MP has been evaluated in Phase I and II clinical trials for the treatment of various cancers, including malignant melanoma, renal cell carcinoma, and chronic lymphocytic leukemia. This drug has also shown promise as a chemotherapeutic agent for AIDS patients with HIV infection or AIDS-related complex.</p>Formula:C4H3N5OSPurity:Min. 95%Color and Shape:PowderMolecular weight:169.17 g/mol2'-Deoxyisocytidine
CAS:<p>2'-deoxyisocytidine is a nucleoside that is used in biochemical research. It can be synthesized by two methods: solid-phase synthesis and depyrimidination. 2'-deoxyisocytidine has been shown to be more efficient than other fluorescent nucleosides when used with the excimer laser technique. The stability of this compound has also been shown to be greater than other fluorescein-based compounds, which makes it an appropriate substitute when using phosphoramidite chemistry.</p>Formula:C9H13N3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:227.22 g/mol3'-O-Methyl-5-methylcytidine
CAS:<p>3'-O-Methyl-5-methylcytidine is a nucleoside with antiviral and anticancer properties. It has been shown to be an activator of RNA polymerase, the enzyme that catalyzes the transcription of DNA into RNA. 3'-O-Methyl-5-methylcytidine binds to the active site of RNA polymerase and is able to stimulate transcription in vitro. This drug has also been shown to have high purity and high quality.</p>Formula:C11H17N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:271.27 g/mol3'-O, N4-Diacetyl-2'-deoxycytidine
<p>3'-O, N4-Diacetyl-2'-deoxycytidine is a modified nucleoside that has anticancer and antiviral activities. It inhibits the synthesis of DNA by preventing the formation of deoxyribonucleotide triphosphates. 3'-O, N4-Diacetyl-2'-deoxycytidine is a novel nucleoside with high purity and high quality. The CAS number for this product is 61428-37-5. This product can be used as starting material in the synthesis of phosphoramidites or modified oligonucleotides.</p>Formula:C13H17N3O6Purity:Min. 95%Molecular weight:311.29 g/mol2'-Deoxy-2'-fluoroadenosine
CAS:<p>2’-Deoxy-2’-fluoro nucleosides and nucleotides have been shown to demonstrate anti-viral activity against influenza, SARS and HIV. More specifically the phosphonate of 2'-Deoxy-2'-fluoroadenosine has been evaluated as an inhibitor of Hepacivirus C (HCV).</p>Formula:C10H12FN5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:269.24 g/molCytarabine hydrochloride
CAS:<p>Anti-viral; anti-neoplastic</p>Formula:C9H13N3O5·HClPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:279.68 g/molCyclopentenyl cytosine 5'-triphosphate sodium salt
<p>Cyclopentenyl cytosine 5'-triphosphate sodium salt is a synthetic, activator diphosphate. It is used as a phosphoramidite in the synthesis of DNA and RNA. Cyclopentenyl cytosine 5'-triphosphate sodium salt has been shown to have anticancer and antiviral properties.</p>Purity:Min. 95%N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine (BDF) is a novel phosphoramidate prodrug of cytosine that has been synthesized for use in antiviral therapy. It is a DNA chain terminator and inhibits viral replication by inhibiting the synthesis of viral DNA. BDF is activated to cytosine monophosphate (CMP) by phosphodiesterase enzymes and then converted to cytosine diphosphate (CDP), which inhibits DNA synthesis. The synthesis of viral RNA is also inhibited, leading to inhibition of protein synthesis and cell death.</p>Formula:C37H34FN3O7Purity:Min. 95%Color and Shape:White solid.Molecular weight:651.7 g/mol2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate
CAS:<p>2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate is a chemical substance that is used as an anticancer and antiviral agent. It has been demonstrated to inhibit the proliferation of tumor cells in vitro and in vivo, and to deplete tumor cell lines of the enzyme ribonucleotide reductase, which is essential for DNA synthesis. The compound also inhibits the synthesis of viral nucleic acid. 2MMAP has a novel chemical structure that includes a methyl group attached to one nitrogen atom. This modification increases its affinity for DNA and RNA molecules by binding to the phosphate groups on these molecules.</p>Formula:C5H7N3OS·H2OPurity:Min. 95%Color and Shape:PowderMolecular weight:175.21 g/molAdenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution
<p>Adenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution is a novel nucleoside that is synthesized from the corresponding phosphoramidites. This compound is an activator of DNA synthesis in mammalian cells and a potent inhibitor of viral replication. It has antiviral activity against HIV, herpes, and influenza viruses. The molecule can be modified to include different substituents such as fluoro, bromo, or chloro groups and has been shown to have anticancer activity.</p>Formula:C24H27BF2N8Na3O13P3SPurity:Min. 95%Molecular weight:878.28 g/mol2',3'-Dideoxycytidine
CAS:<p>Anti-viral; reverse transcriptase inhibitor</p>Formula:C9H13N3O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:211.22 g/molN4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer potential. It is a modified nucleoside that contains an acetyl group at the 4' position. The 3'-OH group has been replaced by a tertiary butyldimethylsilyl group, which renders the compound resistant to deamination by nucleases. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite also shows high purity and high quality.</p>Formula:C47H64N5O9PSiPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:902.11 g/mol5'-O-DMT-2'-O-methyl-5-methyluridine
CAS:<p>5'-O-DMT-2'-O-methyl-5-methyluridine is a modified nucleoside that is used in the synthesis of DNA. It is an anticancer drug and antiviral agent. 5'-O-DMT-2'-O-methyl-5-methyluridine has been shown to inhibit the growth of leukemia cells, even when they are resistant to other drugs. It also inhibits certain viruses, such as herpes simplex virus type 1 (HSV1), by preventing viral replication and inhibiting protein synthesis. This nucleoside is synthesized from 5'-O-DMT and 2'-O-methylcytosine.</p>Formula:C32H34N2O8Purity:Min. 95%Color and Shape:PowderMolecular weight:574.64 g/mol5'-(Furan-2-yl)-2’-O-methyluridine
CAS:<p>5'-(Furan-2-yl)-2’-O-methyluridine is a modified nucleoside that is used as an antiviral agent. It is a monophosphate nucleotide analog and has been shown to be active against HIV, herpes simplex virus, cytomegalovirus, and Epstein Barr virus. 5'-(Furan-2-yl)-2’-O-methyluridine is synthesized by the phosphoramidite method and has high purity and quality. The CAS number for this compound is 2095417-32-4.</p>Purity:Min. 95%4,6-Diamino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS:<p>4,6-Diamino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a novel antiviral, modified nucleoside monophosphate. It is an inhibitor of the RNA polymerase and is active against both DNA and RNA viruses. 4,6-Diamino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine has been shown to have anticancer properties in vitro and in vivo. It also has been shown to be an activator of the enzyme diphosphate kinase.</p>Purity:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.</p>Purity:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine is a novel antiviral drug that has been synthesized for the treatment of cancer and viral infections. This compound has been modified to increase its antiviral activity, which is due to its ability to inhibit DNA synthesis. The antiviral activity of N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine was shown in vitro using human and mouse cells infected with herpes simplex virus (HSV) type 1 and 2.</p>Purity:Min. 95%Kinetin riboside-5'-diphosphate sodium salt
<p>Kinetin riboside-5'-diphosphate sodium salt is a synthetically modified nucleoside that is used as an activator for DNA synthesis and in the treatment of cancer. Kinetin riboside-5'-diphosphate sodium salt has been shown to have antiviral and anticancer effects, as well as being able to modify the activity of natural substances such as kinetin. This compound has been shown to inhibit tumor growth and reduce the size of some types of tumors in mice. It also inhibits viral replication by blocking viral RNA polymerase activity and inhibiting viral protein synthesis.</p>Purity:Min. 95%2'-O-Methyladenosine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:<p>2'-O-Methyladenosine-5'-triphosphate sodium salt is a novel nucleoside phosphoramidite. It is an activator and it can be used in the synthesis of DNA and RNA. The compound has antiviral properties and has been shown to inhibit DNA replication, protein synthesis, and RNA transcription. The compound also inhibits the growth of cancer cells by inducing apoptosis.</p>Formula:C11H18N5O13P3·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:521.21 g/molN4-Acetylcytidine
CAS:<p>N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.</p>Formula:C11H15N3O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.25 g/molN6-Benzoyl-5'-O-benzoyl-2'-deoxyadenosine
CAS:<p>N6-Benzoyl-5'-O-benzoyl-2'-deoxyadenosine is an antiviral and anticancer compound. It has been shown to be active against a number of viruses, including human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 1, and influenza A virus. It also inhibits DNA polymerase α and β by competitive inhibition, preventing the incorporation of ribonucleotides into DNA. This compound may be used for the treatment of AIDS or as a cytostatic agent for the treatment of leukemia or lymphoma.</p>Formula:C24H21N5O5Purity:Min. 95%Molecular weight:459.47 g/mol8-Hydrazinoadenosine
CAS:<p>8-Hydrazinoadenosine is an inhibitor of phosphodiesterase, which is a key enzyme in the regulation of cellular processes. 8-Hydrazinoadenosine binds to the active site of the enzyme and inhibits its function. This binding prevents hydrolysis of the phosphate bond between two nucleotides and so prevents the formation of a new nucleotide from a nucleoside and a phosphate molecule. 8-Hydrazinoadenosine has been shown to inhibit phosphodiesterases in vitro and in animals, including rat brain and mouse lung. Strategies for 8-hydrazinoadenosine commercialization have been investigated, including attaching it to other molecules that are more easily absorbed by cells or using irradiation to produce 8-aminoadenosine, which can be converted into 8-hydrazinoadenosine.</p>Purity:Min. 95%8-Chloroadenosine
CAS:<p>8-Chloroadenosine is a potent inhibitor of apoptosis, which is the process by which cells die. It has been shown to inhibit cell growth in murine hepatoma cells and synergize with other cytotoxic agents. 8-Chloroadenosine inhibits the activity of bcl-2 protein and thus blocks the release of cytochrome c from mitochondria. This causes DNA damage by inhibiting DNA synthesis and protein synthesis, leading to apoptosis. 8-Chloroadenosine has also been shown to be an active inhibitor of cancer cells, especially myeloma cell lines. The response element for 8-chloroadenosine is located in the promoter region of the gene encoding cyclooxygenase 2 (COX-2), which encodes a protein that produces prostaglandins involved in inflammation and tumor growth. The concentration of camp in cancer tissues determines whether these cells will respond favorably or unfavorably to this drug.</p>Formula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/molDenufosol tetrasodium
CAS:<p>A P2Y2 receptor agonist that has been studied in cystic fibrosis and retinal diseases such as retinal detachment. Denufosol was studied as an inhaled drug for cystic fibrosis, due to its ability to activate an alternative chloride channel and avoiding the defective CFTR chloride channel. This enhances hydration of the lung mucosa and improves mucociliary clearance. The drug did not progress from phase III clinical trials. Denufosol resulted in subretinal fluid reabsorption in in vivo model of retinal detachment.</p>Formula:C18H23N5Na4O21P4Purity:Min. 90 Area-%Color and Shape:PowderMolecular weight:861.25 g/molPolyinosinic acid-polycytidylic acid, homopolymer (1:1)
CAS:<p>Polyinosinic acid-polycytidylic acid (Poly I:C), an agonist of TLR3 toll-like receptors, is a synthetic double-stranded RNA analog, consisting of polyinosinic acid (poly I) paired with polycytidylic acid (poly C), forming a stable duplex structure.PolyI:C stimulates the secretion of pro-inflammatory cytokines and type I interferon through its interaction with endosomal Toll-like receptor 3 (TLR-3) and the cytoplasmic receptors melanoma differentiation-associated gene 5 (MDA-5) and retinoic acid-inducible gene I (RIG-I). This immunostimulant activity makes Poly I:C a useful vaccine adjuvant and is used in vaccine formulations. Poly I:C and its stabilized analogs (e.g., poly-ICLC) are also being actively researched for their dual role in oncology: directly targeting tumors and acting as immune potentiators. For example Poly I:C can induce apoptosis in tumor cells and stimulate immunogenic cell death and is therefore being explored alongside chemotherapy, radiotherapy, and checkpoint inhibitors, helping to overcome resistance mechanisms and strengthen treatment outcomes.We can supply PolyI:C to all stages of your project - from R&D and preclinical phases right up to GMP commercial manufacture. Contact our team for custom Poly I:C products.<br>For more on poly I:C read out blog 'Poly I:C: A Vaccine Adjuvant With Oncological Potential.'</p>Formula:(C10H13N4O8P)x•(C9H14N3O8P)xColor and Shape:PowderN6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine
CAS:<p>N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral compound that inhibits the synthesis of DNA and RNA. It is a synthetic, modified nucleoside with antiviral properties. The compound has been shown to be active against both animal and human tumor cells, as well as being effective in the treatment of viral infections.N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is water soluble and biologically stable.</p>Purity:Min. 95%3'-O-Benzoyl-2'-deoxyuridine
CAS:<p>3'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. 3'-O-Benzoyl-2'-deoxyuridine is also an antiviral agent that has shown efficacy against HIV, HSV, and influenza virus. 3'-O-Benzoyl-2'-deoxyuridine is a phosphoramidite monophosphate that can be used as a building block for DNA or RNA synthesis. It is also a diphosphate that can be used to synthesize modified nucleosides. This product has novel properties and high purity, making it suitable for research purposes.</p>Formula:C16H16N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:332.31 g/molN4-Benzoyl-3'-deoxycytidine
CAS:<p>N4-Benzoyl-3'-deoxycytidine is a novel antiviral agent that has shown activity against DNA and RNA viruses. It is an activator of DNA polymerase, which is essential for replication of viral nucleic acids. The compound is a modified nucleoside with a benzoyl group at the 4' position of the ribose moiety. It also has phosphoramidite, monophosphate, and diphosphate analogues. N4-Benzoyl-3'-deoxycytidine binds to the enzyme DNA polymerase, thereby inhibiting its ability to synthesize deoxyribonucleotides from ribonucleotides. This results in inhibition of viral DNA synthesis and subsequent inhibition of viral replication.</p>Formula:C16H17N3O5Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:331.32 g/mol2'-Deoxy-7-deazaisoguanosine triphosphate
CAS:<p>2'-Deoxy-7-deazaisoguanosine triphosphate is a nucleotide analogue that is used as an antiviral agent in the treatment of HIV. It has potent activity against HIV and other retroviruses, including SIV, FIV, and HTLV-1. 2'-Deoxy-7-deazaisoguanosine triphosphate has been shown to act as an activator of DNA polymerase by enhancing the incorporation of deoxynucleotide triphosphates into DNA. It also inhibits the synthesis of viral DNA by inhibiting the activity of reverse transcriptase enzymes.<br>2'-Deoxy-7-deazaisoguanosine triphosphate can be synthesized from diphosphates and phosphoramidites through a modified phosphoramidite approach that allows for high quality and purity with high yield.</p>Formula:C11H17N4O13P3Purity:Min. 95%Molecular weight:506.19 g/mol2'-C-Methylcytidine
CAS:<p>Broad-spectrum anti-viral; inhibitor of HCV NS5B RNA polymerase</p>Formula:C10H15N3O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:257.25 g/mol7-Deaza 2-C-methyl-N6-methyladenosine
CAS:<p>7-Deaza 2-C-methyl-N6-methyladenosine is a nucleoside that is modified with a methyl group at the 7 position of the deoxyribose ring. It has antiviral and anticancer properties. 7-Deaza 2-C-methyl-N6-methyladenosine is an activator of phosphoramidites, which are compounds that can be used to synthesize DNA or RNA.</p>Formula:C13H18N4O4Purity:Min. 95 Area-%Molecular weight:294.31 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose
CAS:<p>Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.</p>Formula:C9H14N4O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:258.23 g/mol5’(R)-C-Methyl-5-methyluridine
CAS:<p>5’(R)-C-Methyl-5-methyluridine is an nucleoside and a ribonucleoside. It has antiviral, anticancer, and DNA modifying properties. This product is used in research to make phosphoramidites, diphosphates, and deoxyribonucleosides. 5’(R)-C-Methyl-5-methyluridine is also used in the production of modified oligonucleotides as well as other novel DNA compounds.</p>Purity:Min. 95%Adenosine 3',5'-bisphosphate triethylammonium salt - 10mM aqueous solution
CAS:<p>Adenosine 3',5'-bisphosphate triethylammonium salt is a metabolite of adenosine and an ester of triethylamine. The conjugate acid has been isolated from mouse urine. It is a metabolite of adenosine in the liver and is hydrolyzed to adenosine monophosphate and bisphosphate. Adenosine 3',5'-bisphosphate triethylammonium salt is used to study the metabolism of adenosine in mice. It has also been shown that this metabolite can inhibit the growth of E. coli (a bacterium) and mouse erythrocyte mitochondria by blocking ATP synthesis at the level of substrate-level phosphorylation.</p>Formula:C10H15N5O10P2•(C6H15N)xPurity:Min. 95%Molecular weight:427.2 g/molAcetoacetyl coenzyme A lithium salt
CAS:<p>Acetoacetyl coenzyme A lithium salt is a novel phosphoramidite building block. It's a modified nucleoside that can be used in the synthesis of oligonucleotides and DNA. Acetoacetyl coenzyme A lithium salt has antiviral, anticancer, and antifungal activities.</p>Formula:C25H36N7O18P3SLi4·5H2OPurity:Min. 96 Area-%Color and Shape:PowderMolecular weight:965.42 g/molN4,N4,2’-O-Trimethylcytidine
CAS:<p>N4,N4,2’-O-Trimethylcytidine is a novel nucleoside that has been shown to be an anticancer drug. It inhibits the growth of cells by selectively inhibiting their DNA synthesis. N4,N4,2’-O-Trimethylcytidine is also active against viruses and is able to inhibit viral replication by blocking the synthesis of deoxyribonucleosides and phosphoramidites. This compound has been synthesized in high purity and quality with CAS No. 34218-81-0.</p>Formula:C12H19N3O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.3 g/mol5'-Azido-2',5'-dideoxy-2'-fluorouridine
CAS:<p>5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.</p>Formula:C9H10FN5O4Purity:Min. 95%Molecular weight:271.21 g/mol4-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-5-carboxamide
CAS:<p>4-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-5-carboxamide is a synthetic compound that inhibits protein synthesis by binding to the 50S ribosomal subunit. It also prevents viral replication by inhibiting the incorporation of amino acids into proteins. 4-Amino-7-(2-deoxy-b-Dribofuranosyl)-7H pyrrolo[2,3 d]pyrimidin 5 carboxamide binds to the 50S ribosomal subunit and blocks tRNA entry into the A site of the ribosome. This binding prevents translation and transcription of mRNA, effectively inhibiting protein synthesis. It has been shown to be effective against murine leukemia virus (MLV), influenza A virus, and herpes simplex virus type 1 (HSV1) in cell culture</p>Formula:C12H15N5O4Purity:Min. 95%Molecular weight:293.28 g/mol2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:<p>2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is a nucleoside that is used in the synthesis of DNA. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is an antiviral, antineoplastic, and anticancer agent. It has been shown to be active against some strains of HIV and herpes viruses. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt also inhibits DNA polymerase and RNA polymerase, preventing viral replication and transcription.<br>The phosphate group on the 5' end of this molecule can be modified to produce phosphoramidites, diphosphates, or triphosphates.</p>Formula:C9H11FN3O13P3·Li4Purity:Min. 95%Molecular weight:508.88 g/molN4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite
<p>N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite is a novel nucleoside analog that has shown anticancer and antiviral activity. It is a monophosphate, modified nucleoside that inhibits the deoxyribonucleotide biosynthetic pathway in cells. N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite can be used as an activator of ribonuclease S1 and ribonuclease T1, which are enzymes involved in the process of DNA replication. In addition to its use as a therapeutic agent, this compound is also used for research purposes.</p>Formula:C52H66N5O9PSiPurity:Min. 95%Molecular weight:964.17 g/mol5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite
CAS:<p>5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite is a monophosphate, Synthetic, DNA Activator, Anticancer, Modified, Novel, Nucleosides. It has the CAS No. 929904-98-3 and is High purity.</p>Formula:C46H53N6O9PPurity:Min. 95%Molecular weight:864.92 g/mol1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine
CAS:<p>1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine is a cytosine analog that is structurally similar to the antiviral drug tenofovir. It has been shown to be active against human serum and logarithmic growth phase cells, as well as cancer cell lines. 1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine inhibits HIV infection in vitro by binding to the viral reverse transcriptase enzyme, blocking its activity and preventing DNA synthesis. This drug also inhibits the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in cell culture.</p>Formula:C9H12FN3O3Purity:Min. 95%Molecular weight:229.21 g/mol2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil
CAS:<p>2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a novel and high purity anticancer and antiviral agent. It is an activator that has been shown to exhibit antineoplastic activity in vitro. The compound also inhibits the formation of RNA and DNA, which are necessary for the replication of cells. 2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a modified nucleoside that has been synthesized by phosphoramidite chemistry. This product can be used for research purposes and as a starting material for the synthesis of other compounds with similar structures.</p>Formula:C11H12N2O7Purity:Min. 95%Molecular weight:284.22 g/molAdenosine 5'-monophosphate disodium salt
CAS:<p>Adenosine 5'-monophosphate disodium salt (AMP-Na2) is a chemical compound that has been used in the study of metabolic disorders. It belongs to the class of ethylene diamines and has been shown to increase the glomerular filtration rate. Ammonium adenosine 5'-monophosphate disodium salt has also been shown to increase the activity of glutamate decarboxylase, which converts glutamate into GABA, an inhibitory neurotransmitter. The neutral pH optimum for AMP-Na2 is 6.5-7.5, which may be due to its lysine residues. AMP-Na2 has a carbonyl group that can be oxidized by reactive oxygen species and cause oxidative injury to cells in vivo and in vitro. This damage was found mainly in microglia cells, which are responsible for removing dead or damaged neurons from the central nervous system (CNS). AMP-Na2 also activates ad</p>Formula:C10H12N5Na2O7PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:391.19 g/mol8-(Benzyloxy)guanosine
CAS:<p>8-(Benzyloxy)guanosine is a novel nucleoside analog that is an activator of ribonucleotide reductase. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo, as well as inhibit the production of diphosphate from ATP. This compound also has antiviral activity against herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1). 8-(Benzyloxy)guanosine is synthesized by reacting the 8-hydroxy group on guanosine with benzaldehyde, followed by phosphorylation with diphosphate. This compound has CAS No. 3868-36-8 and can be used for research purposes only.</p>Formula:C17H19N5O6Purity:Min. 95 Area-%Color and Shape:White To Off-White SolidMolecular weight:389.36 g/mol5'-O-(4,4'-Dimethoxytrityl)adenosine
CAS:<p>5'-O-(4,4'-Dimethoxytrityl)adenosine is a phosphoramidite that can be used as an activator for the synthesis of DNA. It is also used in the preparation of modified nucleosides and has anticancer activity. 5'-O-(4,4'-Dimethoxytrityl)adenosine is a modified ribonucleoside with high quality and high purity. This product has been shown to have antiviral activity against HIV-1.</p>Formula:C31H31N5O6Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:569.61 g/mol2'-Deoxy-5-hydroxyuridine
CAS:<p>2'-Deoxy-5-hydroxyuridine is a hydrated form of uracil that is used in the synthesis of nucleic acids. It is also a substrate for DNA polymerases and has been shown to inhibit the replication of herpes simplex virus. 2'-Deoxy-5-hydroxyuridine has been shown to have biological properties, such as inhibition of radiation-induced transformation, inhibition of cancer cell growth, and antiviral activity. The mechanism by which 2'-deoxy-5-hydroxyuridine inhibits the replication of herpes simplex virus is unclear but may be due to its ability to inhibit cellular metabolism.</p>Formula:C9H12N2O6Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:244.21 g/mol2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine
<p>2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine is a modified nucleoside that inhibits the proliferation of cancer cells. It has been shown to be effective against HIV, Hepatitis B and C, influenza, herpes simplex virus type 1 and 2, and human cytomegalovirus. This drug is synthesized by phosphoramidite chemistry and is used as a DNA activator in the synthesis of oligonucleotides. 2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine is a novel compound that exhibits high quality with high purity.</p>Purity:Min. 95%N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
CAS:<p>N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.</p>Formula:C38H37N3O8Purity:Min. 95%Color and Shape:PowderMolecular weight:663.72 g/molInosine 5'-triphosphate disodium
CAS:<p>Inosine 5'-triphosphate disodium salt is a phosphoramidite that can be used as an activator for DNA synthesis. It also has antiviral and anticancer properties. Inosine 5'-triphosphate disodium salt is used in the synthesis of deoxyribonucleosides and other nucleotides.</p>Formula:C10H13N4O14P3•Na2Purity:Min. 95%Color and Shape:PowderMolecular weight:552.13 g/mol5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine
CAS:<p>5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine is a novel nucleoside analogue that is an activator of the innate immune system. It is used for the treatment of cancer and viral infections. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has been shown to have anticancer activity against pancreatic, lung, breast, prostate, colon, and leukemia cells in vitro. This drug also inhibits influenza virus A/WSN/33 replication in cell culture by blocking the RNA polymerase complex at the initiation stage. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has also been shown to be active against herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1).</p>Purity:Min. 95%N6-Isobutyryl-2'-O-methyladenosine
<p>N6-Isobutyryl-2'-O-methyladenosine is a nucleoside that has antiviral, anticancer, and anti-inflammatory properties. It is an analog of adenosine that is used in the synthesis of DNA and RNA. It is modified by the incorporation of an iso-butyl group at the 2' position on the ribose ring. N6-Isobutyryl-2'-O-methyladenosine was first synthesized in 1962 and has been extensively studied due to its novel properties. The phosphoramidites are activated with tetrazole or triazole, which are both strong activators. This nucleoside can be synthesized in high purity (>98%) through a modification of the conventional phosphorylation process.</p>Formula:C15H21N5O5Purity:Min. 95%Molecular weight:351.36 g/mol2-Amino-2'-deoxyadenosine
CAS:<p>2-Amino-2'-deoxyadenosine is a modified nucleoside, closely related to adenosine in which the 2'-hydroxyl group is replaced by an amino group. This compound has potential research applications</p>Formula:C10H14N6O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:266.26 g/mol5’-O-Benzoyl-3’-O-(4-methoxybenzoyl)-2’-O,4’-C- methyleneuridine
<p>5'-O-Benzoyl-3'-O-(4-methoxybenzoyl)-2'-O,4'-C-methyleneuridine is a nucleoside that is synthesized from 5'-O-benzoyl-2'-deoxyadenosine and 4'-methoxybenzoyl chloride. It has antiviral and anticancer properties. 5' - O - benzoyl - 3' - O - (4-methoxybenzoyl) - 2' - O,4' - C methyleneuridine is a novel nucleoside with anti-cancer and antiviral effects. It can also be used as an activator for the synthesis of oligonucleotides or as a ribonucleotide phosphoramidite. The chemical name for this compound is 5’ – O – benzoyl – 3’ – O – (4 methoxybenzoyl) – 2</p>Purity:Min. 95%9-Deazaguanosine
CAS:<p>9-Deazaguanosine is a naturally occurring purine, which has been shown to inhibit the binding of adenosine deaminase enzyme. This enzyme is responsible for the conversion of adenosine to inosine, and plays a role in the replication of viruses. 9-Deazaguanosine has also been shown to have an inhibitory effect on trichomonas vaginalis, benzyl groups, and anomers. The hydroxyl group on 9-Deazaguanosine interacts with mammalian cells which may be related to its inhibitory effect on leishmania and hepatitis.</p>Formula:C11H14N4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:282.25 g/mol2’,3’-Bis-O-tert-butyldimethylsilyluridine
CAS:<p>2’,3’-Bis-O-tert-butyldimethylsilyluridine is a modified nucleoside that is used as an antiviral and anticancer agent. It inhibits the RNA polymerase of human immunodeficiency virus (HIV) and prevents the synthesis of viral DNA. It also inhibits tumor growth by inhibiting the enzyme ribonucleotide reductase. 2’,3’-Bis-O-tert-butyldimethylsilyluridine is synthesized by reacting 2′,3′-dideoxyribonucleosides with tertiary butyl dimethylchlorosilane in aqueous media.</p>Purity:Min. 95%N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
<p>N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is an antiviral, anticancer and nucleoside phosphoramidite. It is a novel DNA building block with antiviral activity against HIV and Hepatitis C. The synthesis of N4-acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is based on the reaction of cytosine monophosphate with 2,4,6,-trimethoxybenzoyl chloride. This compound has also been shown to inhibit the proliferation of leukemia cells in vitro and has potential as a chemotherapeutic agent for cancer treatment.</p>Formula:C43H54N5O9PPurity:Min. 95%Molecular weight:815.89 g/mol
