Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine
CAS:3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine is an antiviral drug. It is a modified nucleoside with phosphoramidite and azido groups. This product can be used as an activator for DNA synthesis, in anticancer drug development, as well as in the treatment of HIV. 3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine has been shown to inhibit the growth of human tumor cells by inhibiting protein synthesis and enhancing the production of reactive oxygen species (ROS). It also inhibits the activity of ribonucleotide reductase, which is a critical enzyme for DNA synthesis.Purity:Min. 95%3’-deoxy-3’-fluorosangivamycin
CAS:3’-deoxy-3’-fluorosangivamycin is a modified deoxyribonucleoside with antiviral and anticancer properties. It is an activator of DNA polymerase. 3’-deoxy-3’-fluorosangivamycin has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) in the calf thymus DNA system. This drug is also effective against other viruses, such as herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and influenza A virus. 3′-deoxy-3′-fluorosangivamycin binds to viral DNA and inhibits nucleotide incorporation, leading to inhibition of viral RNA synthesis and protein synthesis.Purity:Min. 95%2,3'-Anhydrouridine 5'-CE phosphoramidite
2,3'-Anhydrouridine 5'-CE phosphoramidite is a novel modified phosphoramidite that can be used in the synthesis of ribonucleosides and DNA. It has antiviral activity, and is being studied as an anticancer drug. 2,3'-Anhydrouridine 5'-CE phosphoramidite has been shown to inhibit the replication of HIV-1 and herpes simplex virus type 1 (HSV-1). The nucleoside analogs are being studied for their potential use in chemotherapy.Formula:C18H27N4O6PPurity:Min. 95%Molecular weight:426.41 g/mol3’-β-Azido-2’,3’-dideoxy-5-fluorouridine
CAS:Please enquire for more information about 3’-beta-Azido-2’,3’-dideoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Purity:Min. 95%1-(2'-Deoxy-2'-fluoro-a-L-arabinofuranosyl)-thymine
CAS:1-(2'-Deoxy-2'-fluoro-α-L-arabinofuranosyl)-thymine (commonly abbreviated as L-FMAU) is a nucleoside analog. It contains an α-L-arabinofuranose sugar instead of the natural β-D-deoxyribose found in DNA. A fluorine (F) substitution at the 2'-position enhances stability and resistance to enzymatic degradation. The thymine nucleobase allows it to mimic natural thymidine, potentially incorporating into DNA synthesis pathways. It can be research for its potential antiviral activity.Formula:C10H13FN2O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:260.22 g/mol6-Amino-3-iodo-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS:6-Amino-3-iodo-4-methoxy-1-(beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and can be used to synthesize DNA and RNA. 6AIOMP binds to the ribonucleotide reductases in cells and inhibits their activity. This prevents the conversion of ribonucleotides into deoxyribonucleotides, which are essential for DNA synthesis.Purity:Min. 95%9-(b-D-Arabinofuranosyl)adenine
CAS:9-(b-D-Arabinofuranosyl)adenine is a nucleoside that is used as an antiviral agent. It binds to viral RNA and inhibits viral replication. 9-(b-D-Arabinofuranosyl)adenine has been shown to have potent side-effect profiles, including myocardial infarct, neuronal death, and immunological reactions. These effects are due to its ability to inhibit the synthesis of guanine nucleotides in the heart and brain cells, which are essential for energy production and neurotransmitter release respectively. 9-(b-D-Arabinofuranosyl)adenine also binds to toll-like receptors (TLRs), which are proteins found on the surface of cells that recognize invading microbes or foreign substances. This binding leads to activation of immune response pathways.Formula:C10H13N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:267.24 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It is synthesized from 5'-O-trityluridine and 2'-deoxyribonucleosides. This nucleoside has antiviral and anticancer properties, which are due to the fact that it inhibits viral replication by inhibiting DNA polymerase and prevents cell proliferation. 2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a high purity, high quality product that can be used in DNA synthesis and cancer treatment.Formula:C43H57N4O7PSiPurity:Min. 95%Molecular weight:801.02 g/mol1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-ethyluracil
CAS:1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-ethyluracil is a nucleoside analog with modifications to alter its biological activity. It contains a β-D-arabinofuranose sugar instead of the standard β-D-deoxyribose in natural nucleosides and the fluorine (F) at the 2'-position increases resistance to enzymatic degradation and alters its biological activity. The 5-ethyl modification on the uracil ring enhances its interaction with viral polymerases.Formula:C11H15FN2O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:274.25 g/mol3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
CAS:3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine is a novel synthetic nucleoside that has been shown to have anticancer and antiviral activities. The compound is an activator of the immune system, which may be due to its ability to stimulate the production of interferon and other cytokines. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine can also inhibit viral DNA polymerases. This nucleoside has been shown to inhibit the growth of leukemia cells in culture by inhibiting ribonucleotide reductase activity.Formula:C16H29N3O5SiPurity:Min. 95%Molecular weight:371.51 g/molN4-Benzoyl-5'-O-DMT-5-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-5-methylcytidine is a deoxyribonucleoside that has been modified to make it resistant to nucleases. N4-Benzoyl-5'-O-DMT-5-methylcytidine is an antiviral agent, which inhibits the synthesis of viral DNA by inhibiting the activity of viral DNA polymerase. It also acts as an activator for cellular DNA polymerases and phosphoramidites. The drug can be used in the treatment of HIV and other retroviruses, herpes viruses, and certain types of cancer.Formula:C38H37N3O8Purity:Min. 95%Color and Shape:White SolidMolecular weight:663.73 g/molGuanosine 5'-O-(2-thiodiphosphate) trilithium salt
CAS:Guanosine 5'-O-(2-thiodiphosphate) trilithium salt (GTPTS) is a membrane-permeable molecule that hyperpolarizes cells by inhibiting the movement of ions through the cell membrane. GTPTS is activated by extracellular calcium and potassium ions, which are involved in signal transduction pathways. It has been shown to inhibit the release of neurotransmitters, such as acetylcholine, dopamine, serotonin, and norepinephrine. GTPTS also blocks voltage-gated sodium channels, which leads to a reduction in neuronal excitability. The drug has been shown to have analgesic effects in animal models of pain and can be used to treat chronic pain due to nerve damage.Formula:C10H12Li3N5O10P2SPurity:Min. 85 Area-%Color and Shape:PowderMolecular weight:477.06 g/mol7-Deaza-2'-deoxyxanthosine
CAS:7-Deaza-2'-deoxyxanthosine is an oligodeoxynucleotide that is a substrate for the enzyme dUTPase. The allyl group on 7-deaza-2'-deoxyxanthosine is used to attach it to the 3' end of DNA, where it acts as a competitive inhibitor of RNA synthesis. The ethyl group at the end of the molecule is used to attach it to the 5' end of DNA, where it inhibits transcription and replication by binding with RNA polymerase. 7-Deaza-2'-deoxyxanthosine has been shown to be effective in preventing stenosis following coronary bypass surgery, as well as in treating heart disease by reducing levels of xanthosine.
Formula:C11H13N3O5Purity:Min. 95%Color and Shape:Beige PowderMolecular weight:267.24 g/mol3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine
3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is a nucleoside analog and activator that inhibits the replication of DNA. It is a novel antiviral drug that has antiproliferative properties and may be useful in the treatment of cancer. 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is synthesized by reacting an activated phosphoramidite with 2',3'-dideoxyadenosine monophosphate to produce 3',5' dideoxythymidine 5'-monophosphate, which is then converted to 3',5' dideoxyuridine 5'-monophosphate. The last step involves the conversion of 3',5' dideoxyuridine 5'-monophosphate to 3' azidouridine 5'-monophFormula:C38H34N8O5Purity:Min. 95%Molecular weight:682.73 g/molN2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine
N2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine is a monophosphate analog of guanine. It is a novel antiviral agent that inhibits the DNA polymerase and RNA polymerase activities of human immunodeficiency virus (HIV). The drug has a high purity and is available in large quantities.
Formula:C14H19N5O6Purity:Min. 95%Color and Shape:PowderMolecular weight:353.33 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside and deoxyribonucleoside that has been synthesized by the chemical modification of cytidine. It is an anticancer drug and antiviral agent, which has been shown to activate DNA polymerase, inhibit RNA synthesis and have antiviral activities against HIV, HSV, CMV, and VZV. N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite has high purity with low impurities (0.1% DMSO), making it a valuable nucleoside for use in synthesis of ribonucleotide analogues.Formula:C42H52N5O8PPurity:Min. 97 Area-%Color and Shape:White Off-White PowderMolecular weight:785.86 g/molN4-Benzoyl-2'-deoxy-2'-fluorocytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-deoxy-2'-fluorocytidine 3'-CE phosphoramidite is a novel DNA phosphoramidite monomer that has been modified to include an N4-benzoyl group at the 2'-position of the sugar. It is synthesized from 4,5-diaminopyrimidine, 1,3-bis(2-chloroethyl)carbodiimide hydrochloride (EDC), and 4-(N,N-dimethylamino)benzoic acid. The benzoyl group allows for the incorporation of this monomer into DNA in place of deoxycytidine. This product is designed to be used in oligonucleotide synthesis as an activator.Formula:C46H51FN5O8PPurity:Min. 95%Molecular weight:851.9 g/mol1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione is a nucleoside that is a novel anticancer drug. It has been shown to have potent antineoplastic activity in vitro and in vivo. This compound is an activator of the p53 tumor suppressor gene and may also act as a transcriptional inhibitor of NF-κB.Purity:Min. 95%Kinetin riboside
CAS:Kinetin is a plant hormone that regulates cell proliferation and differentiation. Kinetin riboside is a derivative of kinetin in which the ribose moiety has been converted to ribosyl-ribitol. Kinetin riboside has shown the ability to inhibit cancer cells by inducing apoptosis, which may be related to its ability to inhibit cyclin D2 and mitochondrial membrane potential. In addition, kinetin riboside has been shown to protect against oxidative stress and decrease mitochondrial function in cells. This compound may have therapeutic potential for cancer treatment and other diseases caused by oxidative stress or mitochondrial dysfunction.Formula:C15H17N5O5Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:347.33 g/mol10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite
CAS:10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite is a cholesterol-conjugated phosphoramidite. The cholesteryl group is a lipophilic moiety which can be used to enhance cellular uptake of oligonucleotides.Formula:C46H82N3O7PPurity:(31P-Nmr) Min. 95 Area-%Color and Shape:Colorless PowderMolecular weight:820.13 g/mol3’-Deoxy-5-fluoro-3’-methyluridine
CAS:3’-Deoxy-5-fluoro-3’-methyluridine is a nucleoside that has antiviral and anticancer properties. It is synthesized from 5-fluorouracil, which is a prodrug that is activated by 3’-deoxy-5-fluoro-3’-methyl uridine to produce 5′,6′ difluorodeoxyadenosine. This compound can be used in the treatment of hepatitis B virus and hepatitis C virus infections. 3’-Deoxy-5-fluoro-3’ methyluridine has also been shown to inhibit the growth of cancer cells in vitro.Purity:Min. 95%5-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.Formula:C10H18N3O14P3·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:497.18 g/molN4-Acetyl-2'-deoxy-5'-O-tritylcytidine
CAS:N4-Acetyl-2'-deoxy-5'-O-tritylcytidine is a novel nucleoside that is synthesized by modifying cytidine to form an acetylated nucleotide. It has been found to be an effective inhibitor of DNA synthesis and antiviral agent.Formula:C30H29N3O5Purity:Min. 95%Molecular weight:511.57 g/mol1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)adenine
CAS:1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)adenine is an important compound in the field of nucleoside chemistry and has potential applications in researchFormula:C11H13N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:279.25 g/mol2'-O-Acetyl-3'-deoxy-3-deaza-3'-fluoro-5'-O-toluoyluridine
CAS:2'-O-Acetyl-3'-deoxy-3-deaza-3'-fluoro-5'-O-toluoyluridine is an antiviral agent that has been shown to be active against a number of viruses, including HIV. It is a novel nucleoside analog that has been modified with the addition of acetyl and toluoyl moieties at the 2' position. The compound exhibits high antiviral potency in vitro and in vivo, and has an excellent safety profile. This novel anticancer agent also inhibits DNA synthesis by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase activity.Purity:Min. 95%2',3',5'-Tri-O-acetylguanosine
CAS:2',3',5'-Tri-O-acetylguanosine is a protected form of the nucleoside guanosine which has potential application as a synthetic intermediate in nucleic acid and nucleoside chemistry.Formula:C16H19N5O8Purity:Min. 95%Color and Shape:White PowderMolecular weight:409.35 g/molCytarabine hydrochloride
CAS:Anti-viral; anti-neoplasticFormula:C9H13N3O5·HClPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:279.68 g/mol5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite
5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a nucleoside which is an activator for DNA synthesis. It is synthesized from the natural substance thymidine, and it can be modified to have various properties by changing the chemical group that attaches to the 3' carbon. 5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a novel nucleoside that has been shown to be anticancerous in vitro. This compound may also play a role in treating viral infections due to its antiviral properties.Formula:C25H45N4O6PSiPurity:Min. 95%Molecular weight:556.72 g/mol3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyuridine
CAS:3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyuridine is a novel nucleoside analog with antiviral and anticancer activities. It is an activator that binds to the ribonucleotide reductase enzyme, which is essential for the production of RNA and DNA. This compound has been shown to inhibit the growth of several cancer cells in vitro.Purity:Min. 95%5'-O-p-Anisoyl-2'-deoxyuridine 3'-CE phosphoramidite
5'-O-p-Anisoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer nucleoside analog that inhibits viral replication. It is a modified nucleoside with a 5' anisoyl group and a 2' deoxyuridine moiety. This compound is synthesized by reacting the 5'-O-p-anisoyl-2'-deoxyuridine 3'-cyclohexylphosphate with phosphorus oxychloride to form the 5'-O-p-anisoyl-2'-deoxyuridine 3'-cyanoethyl phosphoramidite, which can be used for the synthesis of DNA or RNA. The phosphoramidite can also be used as an activator in polymerase chain reactions (PCR).Formula:C26H35N4O8PPurity:Min. 95%Molecular weight:562.55 g/mol2'-Deoxy-5-formylcytidine
CAS:2'-Deoxy-5-formylcytidine is a nucleoside analog that is used as a chemotherapeutic agent. It is cytotoxic to cells by binding to DNA and preventing the synthesis of DNA, RNA, and protein. The drug has been shown to induce cellular senescence in human fibroblasts, which can be reversed by the addition of deuterium. 2'-Deoxy-5-formylcytidine also inhibits the production of reactive oxygen species (ROS) by inducing the expression of antioxidant enzymes such as superoxide dismutase 2 and glutathione peroxidase 1. The oxidation products are misincorporated into DNA strands, leading to intramolecular hydrogen bonds with cytosine bases. These modifications lead to denaturation of DNA and inhibition of transcription and replication. 2'-Deoxy-5-formylcytidine also interacts with oligodeoxynucleotides, which leads to misincFormula:C10H13N3O5Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:255.23 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine
CAS:This is a nucleoside analog that has antiviral properties. It is a monophosphate derivative of 2'-deoxy-5'-O-DMT-2'-fluoro-5-methyluridine and has been shown to be an activator of RNA polymerase II transcription in vitro. This compound is also a novel, high quality, high purity reagent for the synthesis of phosphoramidites. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is CAS No. 133324-02-4 and can be used as a diphosphate or DNA nucleoside analog with antiviral properties. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is synthesized by reacting 5' deoxyribose phosphate with the corresponding 2',3' or 4' fluoro amidite in the presence of a base. The ribonucleFormula:C31H31FN2O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:562.59 g/molS-Adenosyl-L-methionine p-toluenesulfonate
CAS:Methyl donor and a cofactor for enzyme-catalyzed methylationsFormula:C15H23N6O5S•C7H7O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:570.64 g/mol5'-O-p-Anisoyl-3'-azido-2',3'-dideoxyuridine
5'-O-p-Anisoyl-3'-azido-2',3'-dideoxyuridine is a compound that inhibits DNA synthesis and viral replication. It is an antiviral agent that inhibits the activation of virus by blocking the incorporation of deoxyribonucleotide triphosphates into viral DNA chains. This compound also has anticancer activity, which may be due to its ability to inhibit RNA synthesis in tumor cells.Formula:C17H17N5O6Purity:Min. 95%Molecular weight:387.35 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.Formula:C38H37N3O8Purity:Min. 95%Color and Shape:PowderMolecular weight:663.72 g/mol6-O-Methyl-2'-deoxyinosine
CAS:6-O-Methyl-2'-deoxyinosine is a modified nucleoside that inhibits the synthesis of DNA and RNA. It is also an anticancer agent, inhibiting the growth of tumor cells by arresting the cell cycle at the G1 phase. 6-O-Methyl-2'-deoxyinosine is a phosphoramidite for use in solid phase synthesis of oligodeoxynucleotides (ODN). This product has high purity, good quality, novel structures and excellent stability.
6-O-Methyl-2'-deoxyinosine can be used to inhibit viral replication by preventing viral DNA from being replicated into double stranded DNA. The antiviral activity of 6-O-methyl 2'-deoxyinosine against HIV has been demonstrated in vitro and in vivo using monophosphate forms.Purity:Min. 95%8-Bromoinosine
CAS:8-Bromoinosine is a potent chemical probe that can be used to study the molecular mechanism of cGMP-dependent protein kinase (PKG). 8-Bromoinosine reacts with the acceptor site in PKG, which is located at the base of the active site cleft. Electrons from hydrogen bond donor sites on 8-bromoadenosine are transferred to chloride ion and the resulting 8-bromoinosine chloride complex is an effective inhibitor of PKG. It has been shown that stereoselectivity plays a role in this reaction mechanism.
Formula:C10H11BrN4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:347.13 g/mol2'-Deoxy-2'-fluoroadenosine
CAS:2’-Deoxy-2’-fluoro nucleosides and nucleotides have been shown to demonstrate anti-viral activity against influenza, SARS and HIV. More specifically the phosphonate of 2'-Deoxy-2'-fluoroadenosine has been evaluated as an inhibitor of Hepacivirus C (HCV).Formula:C10H12FN5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:269.24 g/molN4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite is an activator and antiviral agent that inhibits viral DNA synthesis by terminating the elongation step of viral DNA chain extension. N4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite has a novel structure and is synthesized by modified chemical reactions. It can be used in the synthesis of oligonucleotides or as a building block for the synthesis of other nucleosides.Formula:C44H52N5O9PPurity:Min. 95%Molecular weight:825.89 g/mol5-Methyl-2-thiouridine
CAS:5-Methyl-2-thiouridine is a nucleotide that is found in the type strain of Escherichia coli. It has been shown to be an effective inhibitor of protein synthesis, with optimum concentration at 0.1 mM. 5-Methyl-2-thiouridine binds to the ribosome and inhibits its activity. 5-Methyl-2-thiouridine also interacts with human mitochondrial RNA and alters its structure, leading to an antibody response that protects against infection by the bacteria in question. This nucleotide has also been shown to inhibit bacterial growth in wastewater treatment plants. The chemical structures of 5-methyluridine are similar to those of uridine except for a methyl group on the second carbon atom (5 position). The presence of this methyl group confers increased water permeability and decreased kinetic energy on the molecule, which can be detected using nuclear magnetic resonance spectroscopy.
Formula:C10H14N2O5SPurity:Min. 95%Color and Shape:White PowderMolecular weight:274.29 g/molN6-Benzyladenosine 5'-monophosphate sodium salt monohydrate
CAS:N6-Benzyladenosine 5'-monophosphate sodium salt is a nucleoside that is not identified. It has been shown to be metabolized by adenosine deaminase and may have antitumor activity. N6-Benzyladenosine 5'-monophosphate sodium salt is also a radioactively labeled adenine analog that has been used in the study of metabolic pathways.
Formula:C17H18N5Na2O7P·H2OPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:499.32 g/molN3-Methyl-2’-O-(2-methoxyethyl)uridine
CAS:N3-Methyl-2’-O-(2-methoxyethyl)uridine is a modified nucleoside that is synthesized from deoxyribonucleosides and ribonucleosides. It has antiviral, anticancer, and antifungal properties. N3-Methyl-2’-O-(2-methoxyethyl)uridine has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. This drug also inhibits the growth of human cancer cells in vitro and has been shown to be active against breast cancer cells. N3-Methyl-2’-O-(2-methoxyethyl)uridine is phosphorylated by cellular enzymes to form its active form, which binds to the viral reverse transcriptase enzyme and prevents DNA synthesis.Formula:C13H20N2O7Purity:Min. 95%Molecular weight:316.31 g/mol4-7H-Chloro-5-iodo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
CAS:4-7H-Chloro-5-iodo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine is a modified nucleoside that has been shown to have antiviral, anticancer and activator properties. This compound is synthesized by the reaction of 4,7H chloro 5 Iodo 7 (2 C methyl b D ribofuranosyl) 7 H pyrrolo[2,3 d]pyrimidine with 2 C methyl b D ribofuranosyl in aqueous solution at neutral pH. 4 - 7 H Chloro 5 Iodo 7 (2 C methyl b D ribofuranosyl) 7 H pyrrolo [2,3 d] pyrimidine reacts with 2 C methyl b D ribofuranosyl to form 4 - 7 H ChlorPurity:Min. 95%Cytidyl-3'-5'-guanosine ammonium
CAS:Cytidyl-3'-5'-guanosine ammonium salt is a modified nucleoside that has antiviral and anticancer properties. It is synthetically made by modifying the phosphate groups of cytidine and guanosine with phosphoramidites. Cytidyl-3'-5'-guanosine ammonium salt has been shown to activate protein kinase C, which may be related to its anticancer activity.Formula:C19H25N8O12PPurity:Min. 95%Color and Shape:PowderMolecular weight:588.42 g/molN4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine
N4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine is a modified nucleoside that is used as an antiviral agent. It inhibits the activity of reverse transcriptase, which is an enzyme that catalyzes the conversion of RNA into DNA. This nucleoside inhibits viral replication and prevents the production of new viruses in cells infected by HIV. N4-Benzoyl-2’,3’-di-O -tert -butyldimethylsilyl -5’ -O -DMT -N4 methylcytidine also inhibits DNA synthesis by inhibiting the activity of DNA polymerases. This drug has been shown to be effective against cancer cells and may have anticancer properties.Purity:Min. 95%5-Carbamoylmethyluridine
CAS:5-Carbamoylmethyluridine is a nucleoside that is structurally related to uridine. It is synthesized from uridine by methyl esterification with carbamic acid and methoxycarbonyl chloride. 5-Carbamoylmethyluridine interacts with actin filaments and has been shown to alter the expression of messenger RNA in eukaryotes. 5-Carbamoylmethyluridine also acts as a competitive inhibitor of the formation of a ternary complex, which includes ATP, GTP, and UTP, at the level of ribonucleotide reductase. This inhibition leads to decreased synthesis of messenger RNA in cells.Formula:C11H15N3O7Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:301.25 g/mol3'-O-Aminoacetoxythymidine
Amino functionalised thymidineFormula:C13H21N4O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:297.33 g/molAdenosine 5'-phosphosulfate sodium salt, 10 mM in water
CAS:Adenosine 5′-phosphosulfate sodium salt has been used quantify pyrophosphate and in enzyme-linked bioluminescence assay for adenosine triphosphate (ATP).Product provided as 10 mM solution in water.Formula:C10H14N5O10PSPurity:Min. 90.0 Area-%Molecular weight:427.28 g/mol9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine
CAS:9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine is a modified nucleoside with anticancer activity. It has been shown to be an effective activator of DNA, RNA, and protein synthesis in vitro. This drug has also been shown to have antiviral properties against herpes simplex virus type 1 (HSV1) and influenza A virus. 9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine is an analog of the natural purine metabolite hypoxanthine that can be synthesized in high purity.Purity:Min. 95%1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D- ribo-hex-5-enofu ranosyl]uracil
5-Deoxy-2'-O-methylcytidine is a phosphoramidite nucleoside that has antiviral, anticancer, and antifungal properties. It is used as an activator in the synthesis of oligonucleotides and as a reagent for the synthesis of other nucleotide analogues. 5-Deoxy-2'-O-methylcytidine has been shown to have a novel mechanism of action, which targets DNA polymerase alpha and inhibits replication. This drug also has antiangiogenic activity, which may be due to its ability to inhibit the production of VEGF.Purity:Min. 95%N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS:N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine (BDF) is a novel phosphoramidate prodrug of cytosine that has been synthesized for use in antiviral therapy. It is a DNA chain terminator and inhibits viral replication by inhibiting the synthesis of viral DNA. BDF is activated to cytosine monophosphate (CMP) by phosphodiesterase enzymes and then converted to cytosine diphosphate (CDP), which inhibits DNA synthesis. The synthesis of viral RNA is also inhibited, leading to inhibition of protein synthesis and cell death.Formula:C37H34FN3O7Purity:Min. 95%Color and Shape:White solid.Molecular weight:651.7 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-inosine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-inosine 3'-CE phosphoramidite is a modified ribonucleoside with antiviral and anticancer properties. Its DNA synthesis inhibitory activity has been shown in vitro. It is capable of inhibiting the growth of cells infected with influenza A virus, herpes simplex virus type 2, and human lymphocytic leukemia cells. This compound can also be used to produce synthetic oligonucleotides for research purposes. SELECTIVE: The following description should only be used for products that are specifically designed for one gender or age group:Formula:C46H61N6O8PSiPurity:Min. 96 Area-%Color and Shape:PowderMolecular weight:885.07 g/mol5-(Azidomethyl)-2’-deoxyuridine
CAS:5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.
Formula:C10H13N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:283.24 g/mol2',3'-Dideoxycytidine
CAS:Anti-viral; reverse transcriptase inhibitorFormula:C9H13N3O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:211.22 g/mol3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate
CAS:3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is an antiviral and anticancer agent that is used for the synthesis of DNA and RNA. It is a novel nucleoside analog that has been modified to be activated by phosphoramidite chemistry. 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is synthesized from 2,6-diisopropylaniline, methyl 3-(aminomethyl)-1H-pyrrole-2,4-dicarboxylate, and propylamine in cyclohexane at reflux.Formula:C13H22N3O14P3Purity:Min. 95%Molecular weight:537.25 g/mol5'-O-Pixylthymidine
5'-O-Pixylthymidine is a modified nucleoside that has been shown to have anticancer and antiviral activity. It is an analog of thymidine, which is a deoxynucleoside. 5'-O-Pixylthymidine can be converted into diphosphate form by addition of phosphoramidites or ribonucleosides. This nucleotide can also be used as a building block for the synthesis of oligonucleotides, which are synthetic DNA molecules with therapeutic applications.Formula:C29H26N2O6Purity:Min. 95%Molecular weight:498.53 g/mol3’-b-C-Methyladenosine
CAS:3’-b-C-Methyladenosine is a novel antiviral and anticancer agent that is synthetically derived from deoxyribonucleosides. 3’-b-C-Methyladenosine has been shown to have antiviral activity against HIV, influenza, herpes simplex virus type 1 and type 2, and vaccinia virus. It also has anticancer activity against leukemia cells. 3’-b-C-Methyladenosine can be used as a phosphoramidite in the synthesis of oligonucleotides. It may be useful as an activator for nucleophilic substitution reactions with phosphorus halides.Purity:Min. 95%Adenosine 2',3'-cyclic monophosphate sodium
CAS:Adenosine 2',3'-cyclic monophosphate sodium (AMP-Na) is a chemical compound that is found in Streptomyces coelicolor. It has been shown to have an active role in the biotechnology industry for research and development. AMP-Na inhibits the synthesis of carbohydrates by binding to enzymes such as adenosyl-l-methionine peroxidase, which is involved in the metabolism of carbohydrates. Adenosine 2',3'-cyclic monophosphate sodium also has a long half-life, which makes it useful for therapeutic purposes.Formula:C10H11N5NaO6PPurity:Min. 95%Color and Shape:PowderMolecular weight:351.19 g/mol5-b-D-Glucopyranosyl-5-thio-thymine
5-b-D-Glucopyranosyl-5-thio-thymine is a novel, synthetic nucleoside that has antiviral activity. It is deoxyribonucleosides and ribonucleosides, which are the building blocks of DNA and RNA respectively. 5-b-D-Glucopyranosyl-5-thio-thymine can be used as an activator for phosphoramidites, which are used in the synthesis of DNA and RNA. This modified nucleotide also has anti cancer properties as it inhibits the growth of tumor cells.Purity:Min. 95%5-Methoxycarbonylmethyl-2-thiouridine
CAS:Nucleoside functionalised on the baseFormula:C12H16N2O7SPurity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:332.33 g/mol2'-O-Methyladenosine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:2'-O-Methyladenosine-5'-triphosphate sodium salt is a novel nucleoside phosphoramidite. It is an activator and it can be used in the synthesis of DNA and RNA. The compound has antiviral properties and has been shown to inhibit DNA replication, protein synthesis, and RNA transcription. The compound also inhibits the growth of cancer cells by inducing apoptosis.Formula:C11H18N5O13P3·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:521.21 g/mol4,6-Diamino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS:4,6-Diamino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a novel antiviral, modified nucleoside monophosphate. It is an inhibitor of the RNA polymerase and is active against both DNA and RNA viruses. 4,6-Diamino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine has been shown to have anticancer properties in vitro and in vivo. It also has been shown to be an activator of the enzyme diphosphate kinase.Purity:Min. 95%1-(α-D-Ribofuranosyl)uracil
CAS:1-(α-D-Ribofuranosyl)uracil is a nucleoside analog made up of a uracil attached to a ribose sugar at the 1-position, with the sugar in the α configuration. This compound is of interest in biochemistry research and nucleoside chemistry, especially when studying stereochemistry or synthesizing analogs.Formula:C9H12N2O6Purity:(¹H-Nmr) Min. 95 Area-%Color and Shape:PowderMolecular weight:244.2 g/mol2'-Deoxy-5-fluoro-N-methylcytidine
CAS:2'-Deoxy-5-fluoro-N-methylcytidine is a phosphoramidite that belongs to the group of deoxyribonucleosides. It is used as an antiviral agent, with high purity and high quality. 2'-Deoxy-5-fluoro-N-methylcytidine has been shown to inhibit the growth of cancer cells and is also a novel nucleoside with anticancer activity.Formula:C10H14FN3O4Purity:Min. 95%Molecular weight:259.23 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine
CAS:2'-Deoxy-5'-O-DMT-2'-fluorouridine is a medicament that belongs to the group of antineoplastic agents and is used in cancer treatment. It inhibits the synthesis of DNA by inhibiting the enzyme thymidylate synthetase, which is required for the formation of thymine nucleotides. This drug has been shown to be effective against some cancer cells in vitro and in vivo, but not all. 2'-Deoxy-5'-O-DMT-2'-fluorouridine can also inhibit terminal growth phases and induce programmed cell death. Solid phase synthesis has been used to synthesize this molecule as a phosphoramidite.Formula:C30H29FN2O7Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:548.57 g/mol3’-deoxy-3’-fluorotoyocamycin
CAS:3’-deoxy-3’-fluorotoyocamycin is a nucleoside, ribonucleoside and antiviral agent. It inhibits the replication of DNA viruses by inhibiting the viral enzyme RNA polymerase. This drug also has anticancer activity and can be used to treat leukemia and other cancers. 3’-deoxy-3’-fluorotoyocamycin can be used as a monophosphate or diphosphate activator for phosphoramidites in the synthesis of modified DNA. It is also a novel drug that has been modified to contain an additional phosphate group at position 3' on the sugar moiety. The CAS number for this compound is 847649-44-9.Purity:Min. 95%2'-Deoxy-5'-O-DMT-N4-isobutyryl-5-methylcytidine
CAS:The chemical compound 2'-deoxy-5'-O-dimethyltryptophan 4-isobutyryl-5-methylcytidine is an antiviral and anticancer agent. It is a nucleoside analog that inhibits the synthesis of DNA, RNA, and proteins by inhibiting the activity of various enzymes in the cell. This agent also acts as an activator that binds to DNA, preventing transcription of genes. The modified nucleotide has been used in research to study the effects on cancer cells and HIV cells.Purity:Min. 95%5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine
CAS:5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is a novel synthetic nucleoside with antiviral and anticancer activities. It is a phosphoramidite that can be used to synthesize oligonucleotides of any sequence. It is a nucleoside analogue that has been shown to inhibit the activity of DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is also an activator of viral transcription and replication. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine has been shown to be active against methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although it is not active against acid fast bacteria suchFormula:C40H39N5O8Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:717.77 g/molN6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine
CAS:N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral compound that inhibits the synthesis of DNA and RNA. It is a synthetic, modified nucleoside with antiviral properties. The compound has been shown to be active against both animal and human tumor cells, as well as being effective in the treatment of viral infections.N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is water soluble and biologically stable.Purity:Min. 95%3'-O-Benzoyl-2'-deoxyuridine
CAS:3'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. 3'-O-Benzoyl-2'-deoxyuridine is also an antiviral agent that has shown efficacy against HIV, HSV, and influenza virus. 3'-O-Benzoyl-2'-deoxyuridine is a phosphoramidite monophosphate that can be used as a building block for DNA or RNA synthesis. It is also a diphosphate that can be used to synthesize modified nucleosides. This product has novel properties and high purity, making it suitable for research purposes.Formula:C16H16N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:332.31 g/molN4-Benzoyl-3'-deoxycytidine
CAS:N4-Benzoyl-3'-deoxycytidine is a novel antiviral agent that has shown activity against DNA and RNA viruses. It is an activator of DNA polymerase, which is essential for replication of viral nucleic acids. The compound is a modified nucleoside with a benzoyl group at the 4' position of the ribose moiety. It also has phosphoramidite, monophosphate, and diphosphate analogues. N4-Benzoyl-3'-deoxycytidine binds to the enzyme DNA polymerase, thereby inhibiting its ability to synthesize deoxyribonucleotides from ribonucleotides. This results in inhibition of viral DNA synthesis and subsequent inhibition of viral replication.Formula:C16H17N3O5Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:331.32 g/mol2'-Deoxy-7-deazaisoguanosine triphosphate
CAS:2'-Deoxy-7-deazaisoguanosine triphosphate is a nucleotide analogue that is used as an antiviral agent in the treatment of HIV. It has potent activity against HIV and other retroviruses, including SIV, FIV, and HTLV-1. 2'-Deoxy-7-deazaisoguanosine triphosphate has been shown to act as an activator of DNA polymerase by enhancing the incorporation of deoxynucleotide triphosphates into DNA. It also inhibits the synthesis of viral DNA by inhibiting the activity of reverse transcriptase enzymes. 2'-Deoxy-7-deazaisoguanosine triphosphate can be synthesized from diphosphates and phosphoramidites through a modified phosphoramidite approach that allows for high quality and purity with high yield.Formula:C11H17N4O13P3Purity:Min. 95%Molecular weight:506.19 g/mol2'-O-(2-Methoxyethyl)guanosine
CAS:2'-O-(2-Methoxyethyl)guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. This compound has been shown to react with aromatic hydrocarbons to form a reagent that is useful for the alkylation of nucleophilic groups in organic synthesis.Formula:C13H19N5O6Purity:Min. 95%Color and Shape:PowderMolecular weight:341.32 g/mol7-Deaza 2-C-methyl-N6-methyladenosine
CAS:7-Deaza 2-C-methyl-N6-methyladenosine is a nucleoside that is modified with a methyl group at the 7 position of the deoxyribose ring. It has antiviral and anticancer properties. 7-Deaza 2-C-methyl-N6-methyladenosine is an activator of phosphoramidites, which are compounds that can be used to synthesize DNA or RNA.Formula:C13H18N4O4Purity:Min. 95 Area-%Molecular weight:294.31 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose
CAS:Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.Formula:C9H14N4O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:258.23 g/molN3-Methylcytidine
CAS:N3-Methylcytidine is a synthetic analog of uridine. It is used for the treatment of syncytial virus infection, which is a group of diseases caused by viruses that have an RNA genome and replicate by forming syncytia—large groups of infected cells. N3-Methylcytidine inhibits the synthesis of proteins in cells and inhibits the growth of bacteria. This drug has been shown to inhibit actin polymerization and prevents cell spreading. N3-Methylcytidine also binds to RNA polymerase II and blocks its interaction with DNA, inhibiting protein synthesis at the ribosome level. N3-Methylcytidine is metabolized in vivo into methylated cytidine, which can be detected in urine samples using chemical biology methods or fluorescence resonance energy transfer (FRET) analysis. Synonyms: N3-methyluridine; 3-methyluridineFormula:C10H15N3O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:257.24 g/molAdenosine 3',5'-bisphosphate triethylammonium salt - 10mM aqueous solution
CAS:Adenosine 3',5'-bisphosphate triethylammonium salt is a metabolite of adenosine and an ester of triethylamine. The conjugate acid has been isolated from mouse urine. It is a metabolite of adenosine in the liver and is hydrolyzed to adenosine monophosphate and bisphosphate. Adenosine 3',5'-bisphosphate triethylammonium salt is used to study the metabolism of adenosine in mice. It has also been shown that this metabolite can inhibit the growth of E. coli (a bacterium) and mouse erythrocyte mitochondria by blocking ATP synthesis at the level of substrate-level phosphorylation.Formula:C10H15N5O10P2•(C6H15N)xPurity:Min. 95%Molecular weight:427.2 g/mol5,6-Dihydro-5-azacytidine acetate
5,6-Dihydro-5-azacytidine acetate is a monophosphate nucleoside that is used in the synthesis of DNA and RNA. It is an antiviral agent that inhibits the synthesis of DNA by preventing the conversion of deoxyribonucleotides to diphosphates. 5,6-Dihydro-5-azacytidine acetate has been found to have anticancer properties and is used in cancer treatment. This chemical also has a high purity and quality, making it a suitable reagent for use in phosphoramidite coupling reactions for oligonucleotide synthesis. 5,6-Dihydro-5-azacytidine acetate has been shown to be active against a variety of human tumor cell lines, including leukemia cells.Formula:C10H17N4O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:305.26 g/mol3'-Deoxy-3'-fluoro-isocytidine
3'-Deoxy-3'-fluoro-isocytidine is a nucleoside that belongs to the class of Deoxyribonucleosides. It is a novel nucleoside that has antiviral and anticancer properties. 3'-Deoxy-3'-fluoro-isocytidine inhibits viral replication by inhibiting the action of DNA polymerase. It also inhibits cancer cell proliferation through inhibition of DNA synthesis and protein synthesis, as well as induction of apoptosis. 3'-Deoxy-3'-fluoro-isocytidine is phosphorylated by ribonucleotide reductase in the erythrocyte to yield its active form, deoxycytidine monophosphate (dCMP).Purity:Min. 95%5-Bromo-2'-deoxy-2'-fluorouridine
CAS:5-Bromo-2'-deoxy-2'-fluorouridine is a phosphoramidite that can be used as an anticancer, antiviral, and antimalarial agent. It is modified form of nucleosides with a high purity and quality. It has been shown to have antiviral activity against HIV type 1 and influenza A virus in vitro. 5-Bromo-2'-deoxy-2'-fluorouridine is a novel synthetic nucleoside that binds to the ribonucleotide reductase enzyme and inhibits its activity, which prevents the production of RNA. This drug also has anticancer properties due to its ability to inhibit DNA synthesis by binding to DNA polymerase and blocking the incorporation of deoxythymidylate into DNA. It also has been shown to cause cancer cell death by inhibiting protein synthesis.Purity:Min. 95%4-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-5-carboxamide
CAS:4-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-5-carboxamide is a synthetic compound that inhibits protein synthesis by binding to the 50S ribosomal subunit. It also prevents viral replication by inhibiting the incorporation of amino acids into proteins. 4-Amino-7-(2-deoxy-b-Dribofuranosyl)-7H pyrrolo[2,3 d]pyrimidin 5 carboxamide binds to the 50S ribosomal subunit and blocks tRNA entry into the A site of the ribosome. This binding prevents translation and transcription of mRNA, effectively inhibiting protein synthesis. It has been shown to be effective against murine leukemia virus (MLV), influenza A virus, and herpes simplex virus type 1 (HSV1) in cell cultureFormula:C12H15N5O4Purity:Min. 95%Molecular weight:293.28 g/mol5'-Azido-2',5'-dideoxy-2'-fluorouridine
CAS:5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.Formula:C9H10FN5O4Purity:Min. 95%Molecular weight:271.21 g/molN4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite
N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite is a novel nucleoside analog that has shown anticancer and antiviral activity. It is a monophosphate, modified nucleoside that inhibits the deoxyribonucleotide biosynthetic pathway in cells. N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite can be used as an activator of ribonuclease S1 and ribonuclease T1, which are enzymes involved in the process of DNA replication. In addition to its use as a therapeutic agent, this compound is also used for research purposes.Formula:C52H66N5O9PSiPurity:Min. 95%Molecular weight:964.17 g/mol5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite
CAS:5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite is a monophosphate, Synthetic, DNA Activator, Anticancer, Modified, Novel, Nucleosides. It has the CAS No. 929904-98-3 and is High purity.Formula:C46H53N6O9PPurity:Min. 95%Molecular weight:864.92 g/mol1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine
CAS:1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine is a cytosine analog that is structurally similar to the antiviral drug tenofovir. It has been shown to be active against human serum and logarithmic growth phase cells, as well as cancer cell lines. 1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine inhibits HIV infection in vitro by binding to the viral reverse transcriptase enzyme, blocking its activity and preventing DNA synthesis. This drug also inhibits the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in cell culture.Formula:C9H12FN3O3Purity:Min. 95%Molecular weight:229.21 g/mol3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one
CAS:3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a phosphoramidite that can be used for the synthesis of DNA. It has antiviral activity and has been shown to inhibit the growth of cancer cells. 3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a novel nucleoside that is modified with a fluoroquinolone moiety. This modification inhibits viral replication by interfering with viral DNA polymerase. The novel nucleoside has also been shown to have anticancer activity in vitro and in vivo.Formula:C15H15N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:333 g/molAdenosine 5'-monophosphate disodium salt
CAS:Adenosine 5'-monophosphate disodium salt (AMP-Na2) is a chemical compound that has been used in the study of metabolic disorders. It belongs to the class of ethylene diamines and has been shown to increase the glomerular filtration rate. Ammonium adenosine 5'-monophosphate disodium salt has also been shown to increase the activity of glutamate decarboxylase, which converts glutamate into GABA, an inhibitory neurotransmitter. The neutral pH optimum for AMP-Na2 is 6.5-7.5, which may be due to its lysine residues. AMP-Na2 has a carbonyl group that can be oxidized by reactive oxygen species and cause oxidative injury to cells in vivo and in vitro. This damage was found mainly in microglia cells, which are responsible for removing dead or damaged neurons from the central nervous system (CNS). AMP-Na2 also activates adFormula:C10H12N5Na2O7PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:391.19 g/mol8-(Benzyloxy)guanosine
CAS:8-(Benzyloxy)guanosine is a novel nucleoside analog that is an activator of ribonucleotide reductase. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo, as well as inhibit the production of diphosphate from ATP. This compound also has antiviral activity against herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1). 8-(Benzyloxy)guanosine is synthesized by reacting the 8-hydroxy group on guanosine with benzaldehyde, followed by phosphorylation with diphosphate. This compound has CAS No. 3868-36-8 and can be used for research purposes only.Formula:C17H19N5O6Purity:Min. 95 Area-%Color and Shape:White To Off-White SolidMolecular weight:389.36 g/mol5'-O-(4,4'-Dimethoxytrityl)adenosine
CAS:5'-O-(4,4'-Dimethoxytrityl)adenosine is a phosphoramidite that can be used as an activator for the synthesis of DNA. It is also used in the preparation of modified nucleosides and has anticancer activity. 5'-O-(4,4'-Dimethoxytrityl)adenosine is a modified ribonucleoside with high quality and high purity. This product has been shown to have antiviral activity against HIV-1.
Formula:C31H31N5O6Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:569.61 g/mol2'-Deoxy-5-hydroxyuridine
CAS:2'-Deoxy-5-hydroxyuridine is a hydrated form of uracil that is used in the synthesis of nucleic acids. It is also a substrate for DNA polymerases and has been shown to inhibit the replication of herpes simplex virus. 2'-Deoxy-5-hydroxyuridine has been shown to have biological properties, such as inhibition of radiation-induced transformation, inhibition of cancer cell growth, and antiviral activity. The mechanism by which 2'-deoxy-5-hydroxyuridine inhibits the replication of herpes simplex virus is unclear but may be due to its ability to inhibit cellular metabolism.Formula:C9H12N2O6Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:244.21 g/mol2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil
CAS:2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a novel and high purity anticancer and antiviral agent. It is an activator that has been shown to exhibit antineoplastic activity in vitro. The compound also inhibits the formation of RNA and DNA, which are necessary for the replication of cells. 2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a modified nucleoside that has been synthesized by phosphoramidite chemistry. This product can be used for research purposes and as a starting material for the synthesis of other compounds with similar structures.Formula:C11H12N2O7Purity:Min. 95%Molecular weight:284.22 g/mol2-Chloro-6-O-methylinosine
CAS:2-Chloro-6-O-methylinosine is a modified nucleoside analog. Its structure is based on inosine and at position 2 a chlorine atom replaces the hydrogen. At position 6, the keto oxygen (normally part of the purine ring) is O-methylated, forming a methoxy group (-OCH₃)Formula:C11H13ClN4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:316.7 g/molInosine 5'-triphosphate disodium
CAS:Inosine 5'-triphosphate disodium salt is a phosphoramidite that can be used as an activator for DNA synthesis. It also has antiviral and anticancer properties. Inosine 5'-triphosphate disodium salt is used in the synthesis of deoxyribonucleosides and other nucleotides.Formula:C10H13N4O14P3•Na2Purity:Min. 95%Color and Shape:PowderMolecular weight:552.13 g/mol5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine
CAS:5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine is a novel nucleoside analogue that is an activator of the innate immune system. It is used for the treatment of cancer and viral infections. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has been shown to have anticancer activity against pancreatic, lung, breast, prostate, colon, and leukemia cells in vitro. This drug also inhibits influenza virus A/WSN/33 replication in cell culture by blocking the RNA polymerase complex at the initiation stage. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has also been shown to be active against herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1).Purity:Min. 95%N6-Isobutyryl-2'-O-methyladenosine
N6-Isobutyryl-2'-O-methyladenosine is a nucleoside that has antiviral, anticancer, and anti-inflammatory properties. It is an analog of adenosine that is used in the synthesis of DNA and RNA. It is modified by the incorporation of an iso-butyl group at the 2' position on the ribose ring. N6-Isobutyryl-2'-O-methyladenosine was first synthesized in 1962 and has been extensively studied due to its novel properties. The phosphoramidites are activated with tetrazole or triazole, which are both strong activators. This nucleoside can be synthesized in high purity (>98%) through a modification of the conventional phosphorylation process.Formula:C15H21N5O5Purity:Min. 95%Molecular weight:351.36 g/mol2-Amino-2'-deoxyadenosine
CAS:2-Amino-2'-deoxyadenosine is a modified nucleoside, closely related to adenosine in which the 2'-hydroxyl group is replaced by an amino group. This compound has potential research applicationsFormula:C10H14N6O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:266.26 g/mol5’-O-Benzoyl-3’-O-(4-methoxybenzoyl)-2’-O,4’-C- methyleneuridine
5'-O-Benzoyl-3'-O-(4-methoxybenzoyl)-2'-O,4'-C-methyleneuridine is a nucleoside that is synthesized from 5'-O-benzoyl-2'-deoxyadenosine and 4'-methoxybenzoyl chloride. It has antiviral and anticancer properties. 5' - O - benzoyl - 3' - O - (4-methoxybenzoyl) - 2' - O,4' - C methyleneuridine is a novel nucleoside with anti-cancer and antiviral effects. It can also be used as an activator for the synthesis of oligonucleotides or as a ribonucleotide phosphoramidite. The chemical name for this compound is 5’ – O – benzoyl – 3’ – O – (4 methoxybenzoyl) – 2Purity:Min. 95%9-Deazaguanosine
CAS:9-Deazaguanosine is a naturally occurring purine, which has been shown to inhibit the binding of adenosine deaminase enzyme. This enzyme is responsible for the conversion of adenosine to inosine, and plays a role in the replication of viruses. 9-Deazaguanosine has also been shown to have an inhibitory effect on trichomonas vaginalis, benzyl groups, and anomers. The hydroxyl group on 9-Deazaguanosine interacts with mammalian cells which may be related to its inhibitory effect on leishmania and hepatitis.
Formula:C11H14N4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:282.25 g/mol2’,3’-Bis-O-tert-butyldimethylsilyluridine
CAS:2’,3’-Bis-O-tert-butyldimethylsilyluridine is a modified nucleoside that is used as an antiviral and anticancer agent. It inhibits the RNA polymerase of human immunodeficiency virus (HIV) and prevents the synthesis of viral DNA. It also inhibits tumor growth by inhibiting the enzyme ribonucleotide reductase. 2’,3’-Bis-O-tert-butyldimethylsilyluridine is synthesized by reacting 2′,3′-dideoxyribonucleosides with tertiary butyl dimethylchlorosilane in aqueous media.Purity:Min. 95%N4,N4,2’-O-Trimethylcytidine
CAS:N4,N4,2’-O-Trimethylcytidine is a novel nucleoside that has been shown to be an anticancer drug. It inhibits the growth of cells by selectively inhibiting their DNA synthesis. N4,N4,2’-O-Trimethylcytidine is also active against viruses and is able to inhibit viral replication by blocking the synthesis of deoxyribonucleosides and phosphoramidites. This compound has been synthesized in high purity and quality with CAS No. 34218-81-0.Formula:C12H19N3O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.3 g/mol
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