G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Aplindore Fumarate
CAS:189681-71-8
Aplindore Fumarate (DAB-452), a selective dopamine D2/D3 partial agonist, is used in Parkinson's and schizophrenia …
Formula:
C22H22N2O7
Purity:
100%
Color and Shape:
Solid
Molecular weight:
426.42
Ref: TM-T30098
| 1mg | 274.00 € | ||
| 5mg | 681.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,421.00 € | ||
| 50mg | 1,839.00 € | ||
| 100mg | 2,601.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
VA-K-14 hydrochloride
CAS:1171341-19-7
VA-K-14 hydrochloride(VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits …
Formula:
C18H16ClN3S
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
341.86
Ref: TM-T29087
| 1mg | 58.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 182.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 599.00 € | ||
| 100mg | 916.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Ricasetron
CAS:117086-68-7
Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysing properties and is used …
Formula:
C19H27N3O
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
313.44
Ref: TM-T28537
| 1mg | 214.00 € | ||
| 5mg | 543.00 € | ||
| 10mg | 771.00 € | ||
| 25mg | 1,199.00 € | ||
| 50mg | 1,621.00 € | ||
| 100mg | 2,183.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
ADR-851 free base
CAS:138559-56-5
ADR-851 free base is an antagonist of the HT3 receptor.
Formula:
C14H18ClN3O2
Purity:
97.88% - 98.32%
Color and Shape:
Solid
Molecular weight:
295.77
Ref: TM-T23642
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Pitolisant
CAS:362665-56-3
Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human …
Formula:
C17H26ClNO
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
295.85
Ref: TM-T60636
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 306.00 € | ||
| 500mg | 734.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Parogrelil Free Base
CAS:139145-27-0
Parogrelil Free Base is a phosphodiesterase inhibitor, improves claudication-limited exercise performance in patients with peripheral …
Formula:
C19H18BrClN4O2
Purity:
98.48% - 99%
Color and Shape:
Liquid
Molecular weight:
449.73
Ref: TM-T70793
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
5-HT3 antagonist 3
CAS:120635-47-4
5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 …
Formula:
C20H21N3O
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
319.4
Ref: TM-T10162
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 775.00 € | ||
| 100mg | 1,040.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Remoxipride hydrochloride
CAS:73220-03-8
Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, …
Formula:
C16H24BrClN2O3
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
407.73
Ref: TM-T23232
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 389.00 € | ||
| 100mg | 574.00 € | ||
| 500mg | 1,187.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
SKF83959
CAS:80751-85-5
SKF83959: dopamine D1 partial agonist, Ki: D1(1.18 nM), D5(7.56 nM), D2(920 nM), D3(399 nM); improves …
Formula:
C18H20ClNO2
Purity:
98.45%
Color and Shape:
Liquid
Molecular weight:
317.81
Ref: TM-T60835
| 1mg | 52.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 353.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 741.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
2-Methyl-5-HT hydrochloride
CAS:845861-49-6
2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
Formula:
C11H15ClN2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
226.7
Ref: TM-T10075L2
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
SB 218795
CAS:174635-53-1
SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM …
Formula:
C25H20N2O3
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
396.44
Ref: TM-T23316
| 1mg | 52.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 325.00 € | ||
| 50mg | 530.00 € | ||
| 100mg | 737.00 € | ||
| 500mg | 1,560.00 € | ||
| 1mL*10mM (DMSO) | 115.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Pavinetant
CAS:941690-55-7
Pavinetant (MLE-4901) is an orally available neurokinin-3 receptor (NK3R) antagonist used to improve menopausal symptoms.
Formula:
C26H25N3O3S
Purity:
99.60%
Color and Shape:
Solid
Molecular weight:
459.56
Ref: TM-T16114
| 1mg | 80.00 € | ||
| 2mg | 102.00 € | ||
| 5mg | 173.00 € | ||
| 10mg | 257.00 € | ||
| 25mg | 343.00 € | ||
| 50mg | 429.00 € | ||
| 100mg | 618.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Rezatomidine
CAS:847829-38-3
Rezatomidine (AGN203818) is a selective antagonist of α2-adrenergic receptor and can be used in studies …
Formula:
C13H16N2S
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
232.34
Ref: TM-T34308
| 1mg | 183.00 € | ||
| 2mg | 272.00 € | ||
| 5mg | 416.00 € | ||
| 10mg | 611.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,290.00 € | ||
| 100mg | 1,762.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
FRG8701
CAS:108498-50-6
FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to …
Formula:
C22H30N2O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
418.55
Ref: TM-T11324
| 25mg | 1,410.00 € | ||
| 50mg | 1,852.00 € | ||
| 100mg | 2,338.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
S 16924
CAS:734513-52-1
S 16924 is a 5-HT 1A agonist with potential anxiolytic effects and may be useful …
Formula:
C22H24FNO4
Purity:
98.23% - 99.45%
Color and Shape:
Solid
Molecular weight:
385.43
Ref: TM-T28638
| 1mg | 277.00 € | ||
| 5mg | 681.00 € | ||
| 10mg | 931.00 € | ||
| 25mg | 1,434.00 € | ||
| 50mg | 1,867.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
DL-071-IT
CAS:55104-39-7
DL-071-IT (Afurolol Hydrochloride) is a potent non-selective beta-adrenoceptor antagonist.
Formula:
C15H22ClNO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
315.79
Ref: TM-T5450
| 5mg | 187.00 € | ||
| 10mg | 280.00 € | ||
| 25mg | 504.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
PSB-CB5
CAS:1627710-30-8
PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study …
Formula:
C20H17ClN2O2S
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
384.88
Ref: TM-T27019
| 1mg | 89.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 308.00 € | ||
| 25mg | 515.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
PNU-96391
CAS:146798-66-5
PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 …
Formula:
C15H23NO2S
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
281.41
Ref: TM-T28435
| 1mg | 112.00 € | ||
| 5mg | 242.00 € | ||
| 10mg | 359.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 765.00 € | ||
| 100mg | 1,026.00 € | ||
| 200mg | 1,367.00 € | ||
| 1mL*10mM (DMSO) | 230.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
WAY-260022
CAS:850692-43-2
WAY-260022 is the norepinephrine transporter inhibitor.
Formula:
C21H31F3N2O2
Purity:
98.65% - 99.06%
Color and Shape:
Solid
Molecular weight:
400.48
Ref: TM-T23711
| 1mg | 273.00 € | ||
| 2mg | 407.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,415.00 € | ||
| 50mg | 1,832.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
Opigolix
CAS:912587-25-8
Opigolix is a Gonadotropin-releasing hormone receptor antagonist.
Formula:
C25H19F3N4O5S
Purity:
98.07% - 99.54%
Color and Shape:
Solid
Molecular weight:
544.5
Ref: TM-T17301
| 1mg | 273.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 930.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,599.00 € |
Estimated delivery in United States, on Tuesday 14 Jan 2025
