G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Safotibant
CAS:633698-99-4
Safotibant (LF-22-0542) is a bradykinin B1 receptor antagonist with anti-inflammatory and analgesic activity for the …
Formula:
C25H34N4O5S
Purity:
99% - 99.53%
Color and Shape:
Solid
Molecular weight:
502.63
Ref: TM-T34485
| 1mg | 141.00 € | ||
| 5mg | 326.00 € | ||
| 10mg | 492.00 € | ||
| 25mg | 803.00 € | ||
| 50mg | 1,103.00 € | ||
| 100mg | 1,476.00 € | ||
| 500mg | 2,974.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Evodenoson
CAS:844873-47-8
Evodenoson (ATL313), a potent A2aR agonist, treats eye diseases, tumors, and immune disorders; potential for …
Formula:
C23H29N7O6
Purity:
100% - 99.74%
Color and Shape:
Solid
Molecular weight:
499.52
Ref: TM-T31731
| 1mg | 233.00 € | ||
| 5mg | 585.00 € | ||
| 10mg | 886.00 € | ||
| 25mg | 1,697.00 € | ||
| 50mg | 2,298.00 € | ||
| 100mg | 3,475.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
MK-0686
CAS:1159193-97-1
MK-0686 is an orally available bradykinin B1 receptor antagonist with potential anti-inflammatory activity.
Formula:
C22H19ClF4N2O4
Purity:
99.56%
Color and Shape:
Liquid
Molecular weight:
486.84
Ref: TM-T33421
| 1mg | 178.00 € | ||
| 5mg | 437.00 € | ||
| 10mg | 644.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,364.00 € | ||
| 100mg | 1,819.00 € | ||
| 500mg | 3,650.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Piclozotan
CAS:182415-09-4
Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral …
Formula:
C23H24ClN3O2
Purity:
99%
Color and Shape:
Solid
Molecular weight:
409.91
Ref: TM-T28414
| 25mg | 1,410.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,320.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
BMS-470539 dihydrochloride
CAS:2341796-82-3
BMS-470539 dihydrochloride is a MC-1 R agonist with anti-inflammatory activity.
Formula:
C32H43Cl2N5O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
632.62
Ref: TM-T10568
| 1mg | 55.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 678.00 € | ||
| 100mg | 1,074.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Glutaminyl Cyclase Inhibitor 1
CAS:2110449-60-8
Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be …
Formula:
C21H24FN3O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
369.43
Ref: TM-T11424
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 552.00 € | ||
| 100mg | 929.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
DOV-216,303 Free Base
CAS:66504-40-3
DOV-216,303 inhibits serotonin, norepinephrine, dopamine reuptake (IC50s: 14, 20, 78 nM) with antidepressant properties.
Formula:
C11H11Cl2N
Purity:
96.7%
Color and Shape:
Solid
Molecular weight:
228.12
Ref: TM-T11087
| 2mg | 45.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 332.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Cyclazosin HCl
CAS:146929-33-1
Cyclazosin HCl is an α-adrenergic receptor antagonist that can be used to study non-arteritic ischemic …
Formula:
C23H28ClN5O4
Purity:
99.44%
Color and Shape:
Liquid
Molecular weight:
473.95
Ref: TM-T70585
| 1mg | 267.00 € | ||
| 5mg | 657.00 € | ||
| 10mg | 898.00 € | ||
| 25mg | 1,397.00 € | ||
| 50mg | 1,820.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
L-694,247
CAS:137403-12-4
L-694,247 is a 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E …
Formula:
C20H21N5O3S
Purity:
98%
Color and Shape:
White Solid
Molecular weight:
411.48
Ref: TM-T19701
| 1mg | 83.00 € | ||
| 5mg | 264.00 € | ||
| 10mg | 451.00 € | ||
| 25mg | 722.00 € | ||
| 50mg | 1,010.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
NUCC-390
CAS:1060524-97-1
NUCC-390, a novel small-molecule CXCR4 receptor agonist, selectively induces CXCR4 receptor internalization while acting antagonistically …
Formula:
C23H33N5O
Purity:
98.18%
Color and Shape:
Solid
Molecular weight:
395.54
Ref: TM-T12269
| 1mg | 147.00 € | ||
| 5mg | 299.00 € | ||
| 10mg | 467.00 € | ||
| 25mg | 762.00 € | ||
| 50mg | 1,060.00 € | ||
| 100mg | 1,426.00 € | ||
| 500mg | 2,759.00 € | ||
| 1mL*10mM (DMSO) | 354.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Eplivanserin
CAS:130579-75-8
Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of …
Formula:
C19H21FN2O2
Purity:
97.04%
Color and Shape:
Solid
Molecular weight:
328.38
Ref: TM-T11217
| 1mg | 182.00 € | ||
| 5mg | 406.00 € | ||
| 10mg | 600.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,281.00 € | ||
| 1mL*10mM (DMSO) | 419.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Endomorphin 1 acetate
CAS:1276123-71-7
Endomorphin 1 acetate is a μ-opioid receptor agonist with antinociceptive and analgesic effects and can …
Formula:
C36H42N6O7
Color and Shape:
Liquid
Molecular weight:
670.75
Ref: TM-T72423
| 2mg | 43.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
GPR35 agonist 2
CAS:494191-73-0
GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist …
Formula:
C17H11FN2O3S
Purity:
97.18% - 98.40%
Color and Shape:
Solid
Molecular weight:
342.34
Ref: TM-T23434
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 786.00 € | ||
| 500mg | 1,606.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
TASP0390325
CAS:1642187-96-9
TASP0390325, a potent and orally active V1B receptor antagonist, has antidepressant and anxiolytic activities in …
Formula:
C25H30Cl2FN5O4
Purity:
98.62%
Color and Shape:
Solid
Molecular weight:
554.44
Ref: TM-T28926
| 1mg | 57.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 743.00 € | ||
| 100mg | 1,208.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
6-Chloromelatonin
CAS:63762-74-3
6-Chloromelatonin: potent, stable melatonin agonist; binds MT2 receptors (pKi=9.77); could help research sleep disorders.
Formula:
C13H15ClN2O2
Purity:
97.90% - 99.36%
Color and Shape:
Solid
Molecular weight:
266.72
Ref: TM-T22530
| 1mg | 325.00 € | ||
| 5mg | 774.00 € | ||
| 10mg | 1,050.00 € | ||
| 25mg | 1,477.00 € | ||
| 50mg | 1,839.00 € | ||
| 100mg | 2,322.00 € | ||
| 500mg | 4,551.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
CJ 033466
CAS:519148-48-2
CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with …
Formula:
C19H28ClN5O
Purity:
98.41%
Color and Shape:
Solid
Molecular weight:
377.91
Ref: TM-T22671
| 1mg | 74.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 277.00 € | ||
| 25mg | 441.00 € | ||
| 50mg | 630.00 € | ||
| 100mg | 847.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 253.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Torbafylline
CAS:105102-21-4
Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, …
Formula:
C16H26N4O4
Purity:
98% - 99%
Color and Shape:
Soild
Molecular weight:
338.4
Ref: TM-T67965
| 1mg | 125.00 € | ||
| 5mg | 299.00 € | ||
| 10mg | 448.00 € | ||
| 25mg | 730.00 € | ||
| 50mg | 1,003.00 € | ||
| 100mg | 1,374.00 € | ||
| 500mg | 2,747.00 € | ||
| 1mL*10mM (DMSO) | 312.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Viloxazine
CAS:46817-91-8
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and …
Formula:
C13H19NO3
Purity:
99.8%
Color and Shape:
Liquid
Molecular weight:
237.29
Ref: TM-T60325
| 1mg | 181.00 € | ||
| 5mg | 409.00 € | ||
| 10mg | 602.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,299.00 € | ||
| 100mg | 1,743.00 € | ||
| 500mg | 3,477.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
GW438014A
CAS:469861-49-2
GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and …
Formula:
C23H23N3O4S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
437.51
Ref: TM-T24121
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 548.00 € | ||
| 500mg | 1,179.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
NRA-0160
CAS:204718-47-8
NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM)
Formula:
C24H23F2N3OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
439.52
Ref: TM-T12252
| 25mg | 1,410.00 € | ||
| 50mg | 1,852.00 € | ||
| 100mg | 2,338.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
