G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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JTE-952
CAS:1255303-54-8
JTE-952: oral, selective Type II CSF-1R inhibitor, IC50 = 13 nM for CSF1R, 261 nM …
Formula:
C30H34N2O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
518.6
Ref: TM-T11729
| 25mg | 1,559.00 € | ||
| 50mg | 2,040.00 € | ||
| 100mg | 2,888.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
GW-803430
CAS:515141-51-2
GW-803430: potent MCH R1 antagonist, pIC50=9.3, orally effective against obesity in animals.
Formula:
C25H24ClN3O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
481.99
Ref: TM-T15450
| 1mg | 63.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 519.00 € | ||
| 50mg | 724.00 € | ||
| 100mg | 975.00 € | ||
| 200mg | 1,319.00 € | ||
| 1mL*10mM (DMSO) | 171.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
IIIM-8
CAS:1128053-62-2
IIIM-8 is a melanogenesis inhibitor that suppresses pigment production in both in vitro and in …
Formula:
C14H17NO4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
263.29
Ref: TM-T79378
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Feb 2025
Gastrin/CCK antagonist 1
CAS:162271-52-5
Gastrin/CCK antagonist 1 is a potent gastrin/CCK antagonist for the study of metabolic system-related diseases.
Formula:
C28H32FN5O4
Purity:
98.33%
Color and Shape:
Solid
Molecular weight:
521.58
Ref: TM-T13260
| 1mg | 650.00 € | ||
| 5mg | 1,671.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
MRS 1754
CAS:264622-58-4
MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a …
Formula:
C26H26N6O4
Purity:
96.12% - 97.48%
Color and Shape:
Solid
Molecular weight:
486.52
Ref: TM-T16140
| 1mg | 45.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 482.00 € | ||
| 100mg | 701.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
ABT-670
CAS:630119-43-6
ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and …
Formula:
C19H23N3O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
325.4
Ref: TM-T14088
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Uridine 5'-diphosphate
CAS:58-98-0
Uridine 5'-diphosphate acts as a P2Y6 receptor agonist, exhibiting an EC50 value of 0.013 μM …
Formula:
C9H14N2O12P2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
404.16
Ref: TM-T78583
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Feb 2025
Tradipitant
CAS:622370-35-8
Tradipitant (VLY-686) is an antagonist of neurokinin-1.
Formula:
C28H16ClF6N5O
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
587.9
Ref: TM-T17156
| 1mg | 59.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 323.00 € | ||
| 50mg | 479.00 € | ||
| 100mg | 684.00 € | ||
| 1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
(±)-Fabesetron hydrochloride
CAS:129299-81-6
FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
Formula:
C18H20ClN3O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
329.82
Ref: TM-T11293
| 25mg | 1,827.00 € | ||
| 50mg | 2,413.00 € | ||
| 100mg | 3,180.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
AEF0117
CAS:1610878-71-1
AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used …
Formula:
C29H40O3
Purity:
99.58%
Color and Shape:
Liquid
Molecular weight:
436.63
Ref: TM-T79909
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 502.00 € | ||
| 500mg | 1,072.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Cenerimod
CAS:1262414-04-9
Cenerimod (ACT-334441) is an S1P1 agonist used in the study of murine experimental autoimmune encephalomyelitis …
Formula:
C25H31N3O5
Purity:
97.43%
Color and Shape:
Solid
Molecular weight:
453.53
Ref: TM-T14924
| 2mg | 42.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 93.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
PAC1R antagonist 1
CAS:2305204-24-2
PAC1R antagonist 1 is a PAC1 receptor antagonist that inhibits the activation of peptides by …
Formula:
C17H17ClN6O2
Purity:
98.43%
Color and Shape:
Liquid
Molecular weight:
372.81
Ref: TM-T78105
| 1mg | 143.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
S1P1 agonist 6
CAS:2433782-42-2
Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting …
Formula:
C25H26F3NO3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
445.47
Ref: TM-T79816
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Feb 2025
Fosnetupitant chloride monohydrochloride
CAS:1643757-72-5
Fosnetupitant chloride monohydrochloride (Pro-netupitant chloride monohydrochloride) is a selective NK1 antagonist exhibiting high affinity for …
Formula:
C31H37Cl2F6N4O5P
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
761.52
Ref: TM-T78104
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Feb 2025
0990CL
CAS:511514-03-7
0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± …
Formula:
C21H21N5
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
343.42
Ref: TM-T13983
| 1mg | 198.00 € | ||
| 5mg | 500.00 € | ||
| 10mg | 723.00 € | ||
| 25mg | 1,096.00 € | ||
| 50mg | 1,505.00 € | ||
| 100mg | 2,024.00 € | ||
| 1mL*10mM (DMSO) | 532.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
NCGC00229600
CAS:1338824-20-6
NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.
Formula:
C30H29N3O3
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
479.57
Ref: TM-T12192
| 1mg | 62.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 205.00 € | ||
| 25mg | 360.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 819.00 € | ||
| 200mg | 1,082.00 € | ||
| 1mL*10mM (DMSO) | 148.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Azelaprag
CAS:2049980-18-7
Azelaprag (AMG 986) is an effective small-molecule apelin receptor agonist. Azelaprag can be used to …
Formula:
C25H29N7O4S
Purity:
97.71% - 99.60%
Color and Shape:
Solid
Molecular weight:
523.61
Ref: TM-T14390
| 1mg | 368.00 € | ||
| 5mg | 1,094.00 € | ||
| 10mg | 1,424.00 € | ||
| 25mg | 2,010.00 € | ||
| 50mg | 2,610.00 € | ||
| 1mL*10mM (DMSO) | 1,296.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Dibenamine hydrochloride
CAS:55-43-6
Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.
Formula:
C16H19Cl2N
Purity:
96.43%
Color and Shape:
Oily Liquid Solid
Molecular weight:
296.23
Ref: TM-T37906
| 500mg | 34.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
5-HT2C agonist-3 free base
CAS:2104810-17-3
5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), …
Formula:
C19H22FNO2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
315.38
Ref: TM-T79803
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Feb 2025
μ opioid receptor agonist 3
CAS:2378397-91-0
Compound 20, identified as μ opioid receptor agonist 3, is a potent µOR agonist that …
Formula:
C22H28N2O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
352.47
Ref: TM-T79430
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
