G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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AC-099 hydrochloride
CAS:849335-07-5
AC-099 hydrochloride is a full agonist of neuropeptide FF2 receptor NPFF2R and a partial agonist …
Formula:
C9H9Cl2F3N4
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
301.1
Ref: TM-T83212
| 5mg | 48.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 127.00 € | ||
| 100mg | 198.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
SB 258719
CAS:195199-95-2
SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.
Formula:
C18H30N2O2S
Purity:
98.59%
Color and Shape:
Solid
Molecular weight:
338.51
Ref: TM-T12855
| 2mg | 35.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 514.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
CB1 inverse agonist 1
CAS:852315-00-5
MRL-650 is an oral, selective CB1 agonist; IC50: CB1=7.5 nM, CB2=4100 nM; anorexigenic effects noted.
Formula:
C25H18Cl3N3O3
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
514.79
Ref: TM-T10694
| 1mg | 113.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 552.00 € | ||
| 50mg | 772.00 € | ||
| 100mg | 1,053.00 € | ||
| 500mg | 2,115.00 € | ||
| 1mL*10mM (DMSO) | 310.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
RTI-13951-33
CAS:2244884-08-8
RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional …
Formula:
C28H33N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
459.58
Ref: TM-T12778L
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
(S)-Bexicaserin
CAS:2035818-21-2
(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and …
Formula:
C15H19F2N3O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
295.33
Ref: TM-T79838
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 27 Jan 2025
5-HT2A antagonist 1
CAS:204643-75-4
5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.
Formula:
C26H28N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
428.53
Ref: TM-T10498
| 25mg | 1,406.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Ogremorphin
CAS:352563-21-4
Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is …
Formula:
C21H17N3OS
Purity:
99.65% - 99.65%
Color and Shape:
Liquid
Molecular weight:
359.44
Ref: TM-T79209
| 1mg | 377.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
ST-1006
CAS:1196994-11-2
ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.
Formula:
C16H20Cl2N6
Purity:
98.31% - 99.56%
Color and Shape:
Solid
Molecular weight:
367.28
Ref: TM-T34709
| 1mg | 186.00 € | ||
| 2mg | 277.00 € | ||
| 5mg | 468.00 € | ||
| 10mg | 750.00 € | ||
| 25mg | 1,217.00 € | ||
| 50mg | 1,500.00 € | ||
| 100mg | 1,867.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
TG6-129
CAS:1164464-14-5
TG6-129 is an EP2 receptor antagonist, blocking PGE2 effects, reducing inflammatory markers with 1.6 µM …
Formula:
C20H18FN5O3S3
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
491.58
Ref: TM-T28958
| 1mg | 119.00 € | ||
| 5mg | 237.00 € | ||
| 10mg | 419.00 € | ||
| 25mg | 686.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,291.00 € | ||
| 500mg | 2,617.00 € | ||
| 1mL*10mM (DMSO) | 337.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
IIIM-8
CAS:1128053-62-2
IIIM-8 is a melanogenesis inhibitor that suppresses pigment production in both in vitro and in …
Formula:
C14H17NO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
263.29
Ref: TM-T79378
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 27 Jan 2025
5-HT2 agonist-1
CAS:2708279-78-9
Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values …
Formula:
C19H23ClN2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
346.85
Ref: TM-T79804
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 27 Jan 2025
RBC10
CAS:362503-73-9
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated …
Formula:
C24H25ClN2O2
Purity:
98.38%
Color and Shape:
Solid
Molecular weight:
408.92
Ref: TM-T24706
| 1mg | 34.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 361.00 € | ||
| 100mg | 525.00 € | ||
| 200mg | 712.00 € | ||
| 1mL*10mM (DMSO) | 83.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
LGD-6972
CAS:1207989-09-0
LGD-6972 is an antagonist of glucagon receptor.
Formula:
C43H46N2O5S
Purity:
98.8% - 99.33%
Color and Shape:
Solid
Molecular weight:
702.9
Ref: TM-T11845
| 1mg | 87.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 461.00 € | ||
| 50mg | 676.00 € | ||
| 100mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 276.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
Vasopressin
CAS:11000-17-2
Vasopressin receptor agonist; antidiuretic
Formula:
C46H65N15O12S2
Purity:
Min. 95%
Color and Shape:
White Powder
Molecular weight:
1,084.23 g/mol
Ref: 3D-FV40959
| 1g | 1,160.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 436.00 € | ||
| 250mg | 647.00 € | ||
| 500mg | 863.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
SB-616234-A
CAS:908601-49-0
SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant …
Formula:
C32H36ClN5O3
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
574.11
Ref: TM-T12847
| 1mg | 103.00 € | ||
| 5mg | 248.00 € | ||
| 10mg | 358.00 € | ||
| 25mg | 542.00 € | ||
| 50mg | 732.00 € | ||
| 100mg | 1,007.00 € | ||
| 200mg | 1,358.00 € | ||
| 1mL*10mM (DMSO) | 313.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
PSB 1115
CAS:152529-79-8
PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.
Formula:
C14H14N4O5S
Purity:
100% - 99.24%
Color and Shape:
Solid
Molecular weight:
350.35
Ref: TM-T23201
| 1mg | 66.00 € | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 10 Feb 2025
SR 142948
CAS:184162-64-9
SR 142948 is a neurotensin (NT) receptor antagonist.
Formula:
C39H51N5O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
685.85
Ref: TM-T23386
| 10mg | 878.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Lumateperone
CAS:313368-91-1
Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).
Formula:
C24H28FN3O
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
393.5
Ref: TM-T21069
| 10mg | 39.00 € | ||
| 25mg | 57.00 € | ||
| 50mg | 83.00 € | ||
| 100mg | 115.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
AMG 837 calcium hydrate
CAS:1259389-38-2
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM.
Formula:
C52H44CaF6O8
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
950.97
Ref: TM-TQ0020
| 2mg | 36.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 282.00 € | ||
| 100mg | 400.00 € | ||
| 200mg | 547.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
YGZ-331
CAS:1350113-04-0
YGZ-331, a sedative hypnotic, acts by elevating GABA levels as a derivative of the adenosine …
Formula:
C19H23N5O4
Color and Shape:
Liquid
Molecular weight:
385.42
Ref: TM-T200016
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 24 Feb 2025
