G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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3-CPMT
CAS:14008-79-8
3-CPMT (FC-1) is a dopamine uptake inhibitor and a potent long-acting antihistaminic agent.
Formula:
C21H25Cl2NO
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
378.33
Ref: TM-T22508
| 1mg | 44.00 € | ||
| 1ml | 91.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 220.00 € | ||
| 50mg | 417.00 € | ||
| 100mg | 616.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
5-O-Demethylnobiletin
CAS:2174-59-6
5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.
Formula:
C20H20O8
Purity:
98% - 99.83%
Color and Shape:
Solid
Molecular weight:
388.37
Ref: TM-T5714
| 1mg | 64.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 357.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 739.00 € | ||
| 500mg | 1,613.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
JMS-17-2
CAS:1380392-05-1
JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).
Formula:
C25H26ClN3O
Purity:
98.70% - ≥98%
Color and Shape:
Solid
Molecular weight:
419.95
Ref: TM-T5849
| 1mg | 40.00 € | ||
| 1ml | 96.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 218.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 500.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
5-HT1A modulator 2 hydrochloride
CAS:3880-76-0
5-HT1A modulator 2 hydrochloride is a modulator of 5-HT1A showing an affinity of 53 nM …
Formula:
C11H16ClNO
Purity:
97%
Color and Shape:
Solid
Molecular weight:
213.7
Ref: TM-T37197
| 1ml | 50.00 € | ||
| 50mg | 34.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Tetrahydroberberine
CAS:522-97-4
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for …
Formula:
C20H21NO4
Purity:
96.65% - 99.89%
Color and Shape:
Solid
Molecular weight:
339.39
Ref: TM-T2874
| 1ml | 57.00 € | ||
| 5mg | 47.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 134.00 € | ||
| 100mg | 184.00 € | ||
| 500mg | 477.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Danirixin
CAS:954126-98-8
Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: …
Formula:
C19H21ClFN3O4S
Purity:
98% - 99.78%
Color and Shape:
Solid
Molecular weight:
441.9
Ref: TM-T5193
| 1mg | 60.00 € | ||
| 1ml | 133.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 736.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Fosaprepitant dimeglumine
CAS:265121-04-8
Fosaprepitant dimeglumine (MK-0517) is a soluble prodrug of aprepitant, which prevents nausea by blocking NK1 …
Formula:
C37H56F7N6O16P
Purity:
97.39% - 98.75%
Color and Shape:
Solid
Molecular weight:
1004.83
Ref: TM-T1790
| 5mg | 49.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 208.00 € | ||
| 100mg | 343.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
L-765314
CAS:189349-50-6
L-765314: potent α1B adrenergic receptor antagonist, used for blood pressure research.
Formula:
C27H34N6O5
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
522.6
Ref: TM-T5511
| 1ml | 64.00 € | ||
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 203.00 € | ||
| 100mg | 300.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Decloxizine dihydrochloride
CAS:13073-96-6
Decloxizine dihydrochloride (UCB 1402 dihydrochloride) is a histamine 1 receptor antagonist.
Formula:
C21H28N2O2·2ClH
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
413.39
Ref: TM-T5495
| 1ml | 95.00 € | ||
| 10mg | 45.00 € | ||
| 25mg | 67.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 131.00 € | ||
| 500mg | 462.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
ML221
CAS:877636-42-5
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s …
Formula:
C17H11N3O6S
Purity:
97.74%
Color and Shape:
Solid
Molecular weight:
385.35
Ref: TM-T4390
| 1ml | 55.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 240.00 € | ||
| 100mg | 435.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
BAR502
CAS:1612191-86-2
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
Formula:
C25H44O3
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
392.62
Ref: TM-TQ0252
| 1mg | 68.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 598.00 € | ||
| 100mg | 813.00 € | ||
| 200mg | 1,089.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
![[Sar9,Met(O2)11]-Substance P](https://static.cymitquimica.com/products/TM/thumb/T7828.jpg)
[Sar9,Met(O2)11]-Substance P
CAS:110880-55-2
[Sar9,Met(O2)11]-Substance P (NA) is an agonist of NK1 receptor.
Formula:
C64H100N18O15S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
1393.66
Ref: TM-T7828
| 1mg | 83.00 € | ||
| 5mg | 267.00 € | ||
| 10mg | 480.00 € | ||
| 25mg | 783.00 € | ||
| 50mg | 1,084.00 € | ||
| 100mg | 1,457.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Clebopride malate
CAS:57645-91-7
Clebopride malate is a dopamine antagonist drug Used to treat functional gastrointestinal disorders such as …
Formula:
C24H30ClN3O7
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
507.96
Ref: TM-T7569
| 1ml | 37.00 € | ||
| 5mg | 35.00 € | ||
| 10mg | 46.00 € | ||
| 25mg | 68.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 141.00 € | ||
| 200mg | 203.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Exendin-4 acetate
CAS:914454-01-6
Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 …
Formula:
C186H286N50O62S
Purity:
98.65%
Color and Shape:
Solid
Molecular weight:
4247
Ref: TM-T8748
| 1mg | 67.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 193.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 412.00 € | ||
| 100mg | 607.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Nastorazepide
CAS:209219-38-5
Nastorazepide is a selective, orally available antagonist of gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic …
Formula:
C29H36N4O5
Purity:
99.60%
Color and Shape:
Solid
Molecular weight:
520.62
Ref: TM-TQ0062
| 1mg | 52.00 € | ||
| 1ml | 121.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 516.00 € | ||
| 100mg | 744.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Relugolix
CAS:737789-87-6
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) …
Formula:
C29H27F2N7O5S
Purity:
98.64% - 99.67%
Color and Shape:
Solid
Molecular weight:
623.63
Ref: TM-T3630
| 1mg | 36.00 € | ||
| 1ml | 95.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 195.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 500.00 € | ||
| 500mg | 1,075.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
JNJ-37822681
CAS:935776-74-2
JNJ-37822681 is a novel, highly selective dopamine D₂ receptor antagonist characterized by a rapid dissociation …
Formula:
C17H17F5N4
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
372.34
Ref: TM-T27677
| 1mg | 94.00 € | ||
| 2mg | 120.00 € | ||
| 5mg | 181.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 446.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Clomipramine
CAS:303-49-1
Clomipramine treats OCD, depression, chronic pain, and may lower suicide risk in seniors; works by …
Formula:
C19H23ClN2
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
314.85
Ref: TM-T21013
| 1ml | 87.00 € | ||
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 398.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Obestatin (rat) acetate
Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39).
Formula:
C114H174N34O31
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
2516.81
Ref: TM-TP2279L
| 1mg | 74.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 217.00 € | ||
| 25mg | 362.00 € | ||
| 50mg | 515.00 € | ||
| 100mg | 703.00 € | ||
| 200mg | 903.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Spexin acetate(1370290-58-6 free base)
Spexin acetate: GAL2/GAL3 agonist. EC50: 45.7/112.2 nM. Inactive at GAL1. Reduces appetite, fat uptake, and …
Formula:
C76H117N19O22S
Purity:
95.43%
Color and Shape:
Solid
Molecular weight:
1680.94
Ref: TM-TP1930L1
| 1mg | 110.00 € | ||
| 5mg | 246.00 € | ||
| 10mg | 362.00 € | ||
| 25mg | 543.00 € | ||
| 50mg | 759.00 € | ||
| 100mg | 1,035.00 € | ||
| 200mg | 1,392.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
