G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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Opaganib
CAS:915385-81-8
Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).
Formula:
C23H25ClN2O
Purity:
98.86% - 99.71%
Color and Shape:
Solid
Molecular weight:
380.91
Ref: TM-T6750
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 236.00 € | ||
| 50mg | 408.00 € | ||
| 100mg | 602.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Ditolylguanidine
CAS:97-39-2
Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).
Formula:
C15H17N3
Purity:
98.42%
Color and Shape:
White To Pinkish Solid Powder
Molecular weight:
239.32
Ref: TM-T5969
| 1g | 35.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Org 27569
CAS:868273-06-7
Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state …
Formula:
C24H28ClN3O
Purity:
100% - ≥95%
Color and Shape:
Solid
Molecular weight:
409.95
Ref: TM-T2635
| 2mg | 36.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 153.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 412.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Midodrine
CAS:42794-76-3
Midodrine ((±)-Midodrin), an adrenergic alpha-1 agonist, belongs to the class of medications known as vasopressors.
Formula:
C12H18N2O4
Purity:
98.57%
Color and Shape:
Solid
Molecular weight:
254.28
Ref: TM-T22369
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 148.00 € | ||
| 100mg | 214.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
5-O-Demethylnobiletin
CAS:2174-59-6
5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.
Formula:
C20H20O8
Purity:
99.83% - ≥95%
Color and Shape:
Solid
Molecular weight:
388.37
Ref: TM-T5714
| 1mg | 64.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 357.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 739.00 € | ||
| 500mg | 1,613.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Melitracen hydrochloride
CAS:10563-70-9
Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist …
Formula:
C21H26ClN
Purity:
99.82%
Color and Shape:
Crystalline Solid
Molecular weight:
327.9
Ref: TM-T4274
| 10mg | 46.00 € | ||
| 25mg | 67.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 114.00 € | ||
| 200mg | 167.00 € | ||
| 500mg | 272.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Loxiglumide
CAS:107097-80-3
Loxiglumide (CR-1505) is an antagonist of cholecystokinin (CCK-1) receptor.
Formula:
C21H30Cl2N2O5
Purity:
98% - 99.81%
Color and Shape:
Solid
Molecular weight:
461.38
Ref: TM-T2312
| 10mg | 40.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 120.00 € | ||
| 100mg | 196.00 € | ||
| 200mg | 337.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
γ-Mangostin
CAS:31271-07-5
Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an …
Formula:
C23H24O6
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
396.43
Ref: TM-T4S1637
| 1mg | 52.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 448.00 € | ||
| 100mg | 639.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
DORA-22
CAS:1088991-95-0
DORA-22 is a dual orexin receptor antagonist, improves mild stress-induced insomnia with minimal effect on …
Formula:
C23H22F2N4O2
Purity:
97.67%
Color and Shape:
Solid
Molecular weight:
424.44
Ref: TM-T5500
| 1mg | 129.00 € | ||
| 2mg | 184.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 421.00 € | ||
| 25mg | 697.00 € | ||
| 50mg | 976.00 € | ||
| 100mg | 1,319.00 € | ||
| 1mL*10mM (DMSO) | 330.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
NLX-204 hydrochloride(2170405-10-2 free base)
NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = …
Formula:
C20H23Cl2F2N3O2
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
446.32
Ref: TM-T22379L
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
CAY10526
CAS:938069-71-7
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB …
Formula:
C12H7BrO3S
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
311.15
Ref: TM-T23861
| 1mg | 59.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 209.00 € | ||
| 25mg | 419.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
APD668
CAS:832714-46-2
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for …
Formula:
C21H24FN5O5S
Purity:
99.45% - 99.97%
Color and Shape:
Solid
Molecular weight:
477.51
Ref: TM-T2088
| 1mg | 49.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 453.00 € | ||
| 100mg | 639.00 € | ||
| 1mL*10mM (DMSO) | 115.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
6-fluoro-DL-Tryptophan
CAS:7730-20-3
6-fluoro-DL-Tryptophan is an inhibitor of serotonin (5-HT) synthesis.
Formula:
C11H11FN2O2
Purity:
99.25%
Color and Shape:
Off-White Powder
Molecular weight:
222.22
Ref: TM-T7694
| 50mg | 48.00 € | ||
| 100mg | 71.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Pridopidine
CAS:346688-38-8
Pridopidine (FR310826), a low-affinity D2R antagonist, enhances motor skills and has neuroprotective effects in Huntington's …
Formula:
C15H23NO2S
Purity:
95.2% - 99.89%
Color and Shape:
Solid
Molecular weight:
281.41
Ref: TM-T7352
| 2mg | 40.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 322.00 € | ||
| 100mg | 467.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
AZ3451
CAS:2100284-59-9
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
Formula:
C30H27BrN4O3
Purity:
98.12%
Color and Shape:
Solid
Molecular weight:
571.46
Ref: TM-TQ0012
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 228.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 596.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
lumateperone Tosylate
CAS:1187020-80-9
lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist, a partial agonist of presynaptic D2 receptors …
Formula:
C31H36FN3O4S
Purity:
95.83% - 98.57%
Color and Shape:
Solid
Molecular weight:
565.7
Ref: TM-TQ0084
| 5mg | 51.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 334.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Adenosine receptor antagonist 4
CAS:133240-06-9
Adenosine receptor antagonist 4 is an adenosine receptor antagonist.
Formula:
C10H13N3
Purity:
98.59% - 99.58%
Color and Shape:
Off-White Powder
Molecular weight:
175.23
Ref: TM-T21620
| 25mg | 46.00 € | ||
| 50mg | 64.00 € | ||
| 100mg | 94.00 € | ||
| 200mg | 133.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Antalarmin
CAS:157284-96-3
Antalarmin is a CRHR1 antagonist that blocks adrenocorticotropin-releasing hormone-induced hypertension, blocks CRF activation.
Formula:
C24H34N4
Color and Shape:
Liquid
Molecular weight:
378.55
Ref: TM-T70433
| 25mg | 1,397.00 € | ||
| 50mg | 1,820.00 € | ||
| 100mg | 2,297.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
SB399885
CAS:402713-80-8
SB399885 is a potent, brain-penetrant, oral SR-6 antagonist with 200-fold selectivity for SR-6 receptors.
Formula:
C18H21Cl2N3O4S
Purity:
98.94%
Color and Shape:
Solid
Molecular weight:
446.35
Ref: TM-T19669
| 1mg | 94.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 244.00 € | ||
| 25mg | 402.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 762.00 € | ||
| 200mg | 1,025.00 € | ||
| 1mL*10mM (DMSO) | 200.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Bepotastine Besilate
CAS:190786-44-8
Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).
Formula:
C21H25ClN2O3·C6H6O3S
Purity:
99.83% - 99.90%
Color and Shape:
Brown Viscous Liquid
Molecular weight:
547.06
Ref: TM-T6405
| 100mg | 46.00 € | ||
| 500mg | 90.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
